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STARPHARMA HLDGS S/ADR - SPHRY STOCK NEWS

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Rhea-AI Summary

Starpharma has presented promising data on its DEP® cabazitaxel, a nanoparticle formulation of cabazitaxel for advanced prostate cancer (mCRPC), at ESMO 2022. Key findings include a >30% improvement in median progression-free survival (3.9 months vs. 2.9 months) and a 100% response rate among evaluable patients. Compared to standard cabazitaxel, DEP® showed significantly fewer severe treatment-related adverse events (7.5% vs. 39.7%) and no severe hypersensitivity reactions. These results indicate the potential of DEP® cabazitaxel to enhance patient outcomes.

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Starpharma, an Australian biotechnology firm, announced a new DEP® Research Agreement with MSD, the trade name of Merck Sharp & Dohme. This agreement aims to develop and evaluate additional DEP® Antibody Drug Conjugates (ADCs). This initiative follows a previous ADC agreement with MSD in February 2021 and a separate expanded agreement in June 2022 with another US biopharmaceutical company. This partnership is expected to enhance the clinical and commercial value of Starpharma's DEP® technology, which has shown promising results in preclinical studies.

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Starpharma, a Melbourne-based biotech firm, reported positive interim results from its phase 2 trial of DEP® cabazitaxel for prostate cancer. All evaluable patients (Stage IV) showed efficacy responses, with 100% demonstrating significant results. Key findings include:

  • 64% saw tumor size reductions for up to 36 weeks.
  • 90% exhibited a decrease in PSA levels.
  • 83% experienced no progression in secondary bone disease.
  • 56% responded positively across all measures.

These results highlight DEP® cabazitaxel's potential compared to conventional treatments.

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MELBOURNE, Australia, Sept. 15, 2021 /PRNewswire/ -- Starpharma's DEP® cabazitaxel, a nanoparticle version of cabazitaxel, shows enhanced safety with improved side effect profiles compared to Jevtana®. It is in late phase 2 clinical trials for solid tumors, including prostate cancer, with encouraging efficacy signals observed in multiple cancer types despite patients' extensive prior treatments. The US patent granted for DEP® cabazitaxel extends protection until 2039, supporting its unique drug delivery technology. The company plans to advance its clinical program and explore commercial licensing opportunities.

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Starpharma has published new data showing its Viraleze antiviral nasal spray reduces SARS-CoV-2 viral load by over 99.9% in animal models. Conducted at The Scripps Research Institute, the study supports Viraleze's effectiveness against COVID-19 and its variants, including the Delta variant. The findings, featured in Viruses, validate the product's potential as a complementary intervention for COVID-19. Currently, Viraleze is registered for sale in Europe and India, and available online.

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8.14%
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On February 11, 2021, Starpharma (OTCQX: SPHRY) announced a Research Agreement with MSD to evaluate dendrimer-based Antibody Drug Conjugates (ADCs) using their proprietary DEP® technology. This collaboration aims to enhance ADC characteristics, building on Starpharma's successful preclinical studies, including their DEP® HER-2 ADC, which demonstrated significant tumor regression and 100% survival in models. Starpharma already has four clinical-stage oncology products developed from the DEP® technology, one of which is in partnership with AstraZeneca.

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FAQ

What is the market cap of STARPHARMA HLDGS S/ADR (SPHRY)?

The market cap of STARPHARMA HLDGS S/ADR (SPHRY) is approximately 36.4M.
STARPHARMA HLDGS S/ADR

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36.38M
40.61M
Biotechnology
Healthcare
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United States of America
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