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Sangamo Therapeutics Inc - SGMO STOCK NEWS

Welcome to our dedicated page for Sangamo Therapeutics news (Ticker: SGMO), a resource for investors and traders seeking the latest updates and insights on Sangamo Therapeutics stock.

Overview

Sangamo Therapeutics Inc (SGMO) is a genomic medicine company that focuses on advancing gene-based therapeutic development through cutting-edge genomic technologies, in vivo genome editing, and rigorous clinical trials. The company is dedicated to generating transformative treatments for patients afflicted with serious genetic and neurological diseases by integrating breakthrough scientific research with practical clinical applications.

Scientific Innovation and Therapeutic Development

Sangamo leverages a deep expertise in gene editing and gene regulation to explore and develop innovative therapies. Its scientific approach emphasizes both discovery and translational medicine, allowing its research to rapidly move from laboratory innovation to clinical validation. At the heart of its operations is a commitment to precision medicine, using detailed genomic insights to target the molecular causes of disease. This methodical approach not only supports a diversified pipeline but also reinforces the company’s standing within the competitive field of biotechnological research.

Comprehensive Pipeline and Business Model

The company’s pipeline is structured across several therapeutic areas: a priority neurology pipeline addressing conditions such as chronic neuropathic pain and prion diseases; partnered programs which include areas like hemophilia A, oncology, and neurodegenerative disorders such as ALS/FTD and Huntington's Disease; and additional pipelines exploring treatments for conditions including Fabry disease, complications related to renal transplants, inflammatory bowel disease, and multiple sclerosis. This multi-pronged pipeline reflects a dynamic business model that combines internal innovation with strategic collaborations, ensuring that each stage of research and development adheres to strict clinical protocols.

Clinical Integration and Research Excellence

Sangamo’s robust integration of clinical trials with pioneering research underscores its commitment to both safety and efficacy in therapeutic development. By conducting comprehensive clinical studies, including the first in vivo human genome editing trials, the company validates its scientific hypotheses and refines its methodologies. This seamless transition from investigational research to clinical practice is a core strength that enhances its credibility and reliability within the biotech community.

Market Position and Competitive Landscape

Within the competitive biotechnology sector, Sangamo stands out due to its unique synthesis of advanced genomic research, clinical expertise, and strategic partner programs. It operates in a niche yet rapidly evolving market that demands both regulatory rigour and continuous innovation. The firm distinguishes itself by focusing on gene-based therapies that address unmet medical needs, thereby fostering a research environment where scientific precision meets practical application. This balanced approach positions Sangamo as a critical contributor to the fields of genomic medicine and therapeutic innovation.

Answering Key Investor and Research Queries

Sangamo’s strategic initiatives are driven by a clear focus on scientific rigor and therapeutic potential, making it an important subject for investors and researchers alike. The company’s model, which seamlessly integrates research with clinical practice, provides significant insights into the future of precision medicine. Stakeholders seeking a deeper understanding of its methodology will find that each research phase is meticulously designed to validate therapeutic efficacy while mitigating potential risks.

Conclusion and Key Highlights

  • Genomic Medicine Expertise: Specialized in gene-based therapeutic development and in vivo genome editing.
  • Diversified Clinical Pipeline: Encompasses both internally developed therapies and partnered programs across multiple therapeutic areas.
  • Innovative Research Integration: Merges breakthrough scientific innovations with robust clinical trials to ensure patient safety and treatment efficacy.
  • Strategic Market Position: Operates within a high-demand niche, maintaining a balance between research excellence and practical therapeutic applications.
Rhea-AI Summary

Sangamo Therapeutics announced positive preliminary data from its Phase 1/2 PRECIZN-1 study of SAR445136, a gene-edited cell therapy for sickle cell disease (SCD). All four treated patients showed increased total hemoglobin and fetal hemoglobin, with none requiring blood transfusions post-engraftment. The longest-treated patient was followed for 91 weeks. The safety profile was favorable, with no adverse events linked to SAR445136. These findings highlight the therapeutic potential of zinc finger nuclease technology in addressing unmet needs in SCD.

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Sangamo Therapeutics (Nasdaq: SGMO) announced its participation in several upcoming investor conferences. Management will present at the Barclays Gene Editing & Gene Therapy Summit on November 15 at 10:30 a.m. Eastern Time, followed by the Stifel 2021 Virtual Healthcare Conference on the same day at 3:20 p.m. Eastern Time. Additionally, they will participate in the Jefferies London Healthcare Conference on November 16 at 8:40 a.m. Eastern Time. Presentations will be webcasted live and available later on Sangamo's website.

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Sangamo Therapeutics (SGMO) reported its Q3 2021 financial results, revealing a net loss of $47.7 million or $0.33 per share, a significant increase from a loss of $1.6 million in Q3 2020. Revenue dropped to $28.6 million, down from $57.8 million, mainly due to reduced collaboration revenue with Pfizer. Key clinical updates include positive data from its Fabry disease and hemophilia A programs, with plans for a Phase 3 trial for Fabry disease. Additionally, preliminary results for its sickle cell disease therapy will be shared at the ASH meeting in December.

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Sangamo Therapeutics has announced promising preliminary results from the Phase 1/2 STAAR study of isaralgagene civaparvovec (ST-920), a gene therapy for Fabry disease. All four patients in the initial cohorts showed above-normal α-Gal A activity, maintained for up to one year. The company is planning a Phase 3 trial following these results, with one patient withdrawing from enzyme replacement therapy due to stable enzyme activity. There were no Grade 2 or higher adverse events reported.

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Sangamo Therapeutics, Inc. (NASDAQ: SGMO) has announced the release date for its third quarter 2021 financial results, set for November 4, 2021. Following the release, a conference call is scheduled at 9:15 a.m. ET, open to the public through telephone and webcast. Key details include dial-in numbers and a conference ID for participants. Sangamo is a clinical-stage biopharmaceutical firm focused on genomic medicines, leveraging proprietary technology to develop solutions for patients with unmet medical needs. For more information, visit sangamo.com.

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Sangamo Therapeutics (NASDAQ: SGMO) has announced its participation in upcoming investor conferences. The 2021 Virtual Wells Fargo Healthcare Conference is scheduled for September 10 at 3:20 p.m. ET. Next, at the H.C. Wainwright & Co. 23rd Annual Global Investment Conference, Sangamo will present on September 13 at 7:00 a.m. ET. Lastly, the Morgan Stanley 19th Annual Global Healthcare Conference will take place on September 15 at 10:15 a.m. ET. Presentations will be available for webcasting and later on Sangamo's website under Events and Presentations.

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Sangamo Therapeutics, Inc. (Nasdaq: SGMO) will participate in a fireside chat at the 2021 Wedbush PacGrow Healthcare Conference on August 11 at 2:55 PM Eastern Time. The virtual session will be webcast live, providing investors access to insights about the company's genomic medicines pipeline, which leverages zinc finger genome engineering technology. The presentation will be available for later viewing on Sangamo's website, ensuring that stakeholders can stay informed about its progress and strategies in the clinical-stage biopharmaceutical sector.

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Sangamo Therapeutics (SGMO) announced its Q2 2021 financial results, reporting a net loss of $47.2 million or $0.33 per share, up from a loss of $35.9 million in 2020. Q2 revenues reached $27.9 million, a $6.3 million increase year-over-year, attributed to collaboration agreements with Novartis and Biogen. Operating expenses rose to $76.6 million from $59.4 million in Q2 2020. As of June 30, 2021, cash and equivalents totaled $578.9 million. The company reiterated its 2021 expense guidance of $285 million to $305 million.

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Sangamo Therapeutics (Nasdaq: SGMO) announced the release of its second quarter 2021 financial results, scheduled for August 5, 2021, after market close. This will be followed by a conference call at 4:30 p.m. ET, open to the public via phone and webcast. During the call, the company will discuss its financial performance and provide updates on its business operations. Dial-in numbers are provided for domestic and international callers, and a replay will be available for one week post-call.

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Sangamo Therapeutics, Inc. (Nasdaq: SGMO) has appointed Prathyusha Duraibabu as Senior Vice President and Chief Financial Officer, effective June 1, 2021. Duraibabu, who previously served as Principal Accounting Officer, brings over 20 years of experience in financial strategy and operations. Her notable contributions include orchestrating a $140 million follow-on offering and aiding collaborations with Biogen and Novartis, raising an additional $425 million. CEO Sandy Macrae highlighted her leadership and experience in enhancing organizational efficiency.

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FAQ

What is the current stock price of Sangamo Therapeutics (SGMO)?

The current stock price of Sangamo Therapeutics (SGMO) is $0.6853 as of April 16, 2025.

What is the market cap of Sangamo Therapeutics (SGMO)?

The market cap of Sangamo Therapeutics (SGMO) is approximately 157.3M.

What is the core focus of Sangamo Therapeutics Inc?

The company is dedicated to advancing gene-based therapeutic development and in vivo genome editing to treat serious genetic and neurological diseases.

How does Sangamo generate clinical evidence?

Sangamo employs a rigorous integration of scientific research and clinical trials, including pioneering in vivo human genome editing studies, to validate its therapeutic approaches.

What are the main therapeutic areas in Sangamo's pipeline?

The company’s pipeline includes treatments in neurology, partnered programs in hemophilia A, oncology, neurodegenerative diseases, and additional research on conditions like Fabry disease and inflammatory disorders.

How does Sangamo integrate research and clinical development?

It seamlessly transitions innovative laboratory discoveries into clinical trials, ensuring each therapeutic candidate is rigorously evaluated for safety and efficacy.

What distinguishes Sangamo in the competitive biotech market?

Sangamo’s unique methodology of combining advanced genomic research with practical clinical validations, alongside strategic partnerships, sets it apart in the precision medicine field.

What kind of diseases does Sangamo target with its therapies?

The company targets complex genetic and neurological diseases, focusing on conditions that have traditionally been challenging to treat with conventional therapies.

How is Sangamo’s innovation reflected in its business model?

Its business model is built on a dual strategy of developing in-house therapies and collaborating with external partners to expand its pipeline, thereby integrating research excellence with scalable clinical applications.
Sangamo Therapeutics Inc

Nasdaq:SGMO

SGMO Rankings

SGMO Stock Data

157.32M
219.12M
2.17%
27.49%
12.7%
Biotechnology
Biological Products, (no Disgnostic Substances)
Link
United States
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