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Sangamo Therapeutics Inc - SGMO STOCK NEWS

Welcome to our dedicated page for Sangamo Therapeutics news (Ticker: SGMO), a resource for investors and traders seeking the latest updates and insights on Sangamo Therapeutics stock.

Overview

Sangamo Therapeutics Inc (SGMO) is a genomic medicine company that focuses on advancing gene-based therapeutic development through cutting-edge genomic technologies, in vivo genome editing, and rigorous clinical trials. The company is dedicated to generating transformative treatments for patients afflicted with serious genetic and neurological diseases by integrating breakthrough scientific research with practical clinical applications.

Scientific Innovation and Therapeutic Development

Sangamo leverages a deep expertise in gene editing and gene regulation to explore and develop innovative therapies. Its scientific approach emphasizes both discovery and translational medicine, allowing its research to rapidly move from laboratory innovation to clinical validation. At the heart of its operations is a commitment to precision medicine, using detailed genomic insights to target the molecular causes of disease. This methodical approach not only supports a diversified pipeline but also reinforces the company’s standing within the competitive field of biotechnological research.

Comprehensive Pipeline and Business Model

The company’s pipeline is structured across several therapeutic areas: a priority neurology pipeline addressing conditions such as chronic neuropathic pain and prion diseases; partnered programs which include areas like hemophilia A, oncology, and neurodegenerative disorders such as ALS/FTD and Huntington's Disease; and additional pipelines exploring treatments for conditions including Fabry disease, complications related to renal transplants, inflammatory bowel disease, and multiple sclerosis. This multi-pronged pipeline reflects a dynamic business model that combines internal innovation with strategic collaborations, ensuring that each stage of research and development adheres to strict clinical protocols.

Clinical Integration and Research Excellence

Sangamo’s robust integration of clinical trials with pioneering research underscores its commitment to both safety and efficacy in therapeutic development. By conducting comprehensive clinical studies, including the first in vivo human genome editing trials, the company validates its scientific hypotheses and refines its methodologies. This seamless transition from investigational research to clinical practice is a core strength that enhances its credibility and reliability within the biotech community.

Market Position and Competitive Landscape

Within the competitive biotechnology sector, Sangamo stands out due to its unique synthesis of advanced genomic research, clinical expertise, and strategic partner programs. It operates in a niche yet rapidly evolving market that demands both regulatory rigour and continuous innovation. The firm distinguishes itself by focusing on gene-based therapies that address unmet medical needs, thereby fostering a research environment where scientific precision meets practical application. This balanced approach positions Sangamo as a critical contributor to the fields of genomic medicine and therapeutic innovation.

Answering Key Investor and Research Queries

Sangamo’s strategic initiatives are driven by a clear focus on scientific rigor and therapeutic potential, making it an important subject for investors and researchers alike. The company’s model, which seamlessly integrates research with clinical practice, provides significant insights into the future of precision medicine. Stakeholders seeking a deeper understanding of its methodology will find that each research phase is meticulously designed to validate therapeutic efficacy while mitigating potential risks.

Conclusion and Key Highlights

  • Genomic Medicine Expertise: Specialized in gene-based therapeutic development and in vivo genome editing.
  • Diversified Clinical Pipeline: Encompasses both internally developed therapies and partnered programs across multiple therapeutic areas.
  • Innovative Research Integration: Merges breakthrough scientific innovations with robust clinical trials to ensure patient safety and treatment efficacy.
  • Strategic Market Position: Operates within a high-demand niche, maintaining a balance between research excellence and practical therapeutic applications.
Rhea-AI Summary

Sangamo Therapeutics (NASDAQ: SGMO) announced the release of its first quarter 2022 financial results, scheduled for May 5, 2022, after market close. A conference call will be held at 4:30 p.m. ET to discuss the results and provide business updates, accessible via telephone and webcast. Domestic callers can dial (877) 377-7553, while international participants may call (678) 894-3968, using conference ID 3090098. A replay will be available for one week following the event. For more information, visit the Sangamo Therapeutics website.

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Sangamo Therapeutics (Nasdaq: SGMO) announced participation in three upcoming investor conferences. The events are:

  • Bank of America Securities Conference on May 11 at 3:00 p.m. ET
  • RBC Global Healthcare Conference on May 18 at 3:05 p.m. ET
  • H.C. Wainwright Global Investment Conference on May 24 at 7:00 a.m. ET

Access to presentations will be available on the Sangamo Therapeutics website under the Investors and Media section.

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Sangamo Therapeutics (SGMO) announced the dosing of the first patient in its Phase 1/2 STEADFAST clinical study for TX200, an innovative CAR-Treg cell therapy aimed at preventing immune-mediated rejection in HLA-A2 mismatched kidney transplants. This represents a significant milestone in genomic medicine, with hopes of reducing the need for lifelong immunosuppressants. The study aims to assess TX200's safety and effectiveness, marking a potential breakthrough in treating patients receiving kidneys from living donors.

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Sangamo Therapeutics, a genomic medicine company (NASDAQ: SGMO), will participate in three upcoming investor conferences in March 2022. These include the Cowen 42nd Annual Health Care Conference on March 7 at 12:50 p.m. ET, the Barclays Global Healthcare Conference on March 17 at 9:00 a.m. ET, and the H.C. Wainwright & Co. Gene Editing and Therapy Conference on March 30 at 7:00 a.m. ET. Presentations will be accessible via the company’s website in the Investors and Media section post-event.

For more details about Sangamo's innovative genomic medicines pipeline, visit www.sangamo.com.

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Sangamo Therapeutics (SGMO) reported its financial results for Q4 and full year 2021, highlighting advances in genomic medicines across multiple therapeutic areas. The company noted ongoing developments in its gene therapy candidates for Fabry disease and sickle cell disease, alongside its hemophilia A collaboration with Pfizer. However, the firm reported a consolidated net loss of $178.3 million for 2021, compared to a loss of $121.1 million in 2020. Cash, cash equivalents, and marketable securities decreased to $464.7 million by year-end. 2022 operating expense guidance is set between $320 million and $350 million.

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Sangamo Therapeutics, Inc. (Nasdaq: SGMO) announced the release date for its fourth quarter and full year 2021 financial results, scheduled for February 24, 2022, after market close. Following this, a conference call will take place at 4:30 p.m. ET to discuss the results and provide business updates. The call can be accessed via telephone or webcast. Details for call-in numbers and a link to the live webcast are available on the company's website. Sangamo focuses on developing genomic medicines for diseases lacking adequate treatment options.

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Sangamo Therapeutics has reported updated results from the Phase 1/2 STAAR study of isaralgagene civaparvovec (ST-920), a gene therapy for Fabry disease. As of November 9, 2021, the treatment was well tolerated across five patients, with α-Gal A activity significantly elevated in four patients (3-15 times above normal). The fifth patient in the third cohort showed mean normal levels at week 2. Notably, there were no serious adverse events. Sangamo plans to advance to Phase 3 following the completion of the current study, with further results expected throughout 2022.

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Sangamo Therapeutics, Inc. announced that Sanofi will transition its rights for SAR445136, a gene-edited cell therapy for sickle cell disease, back to Sangamo in the first half of 2022. This change follows Sanofi's decision to terminate their collaboration, citing a shift in strategy. The Phase 1/2 PRECIZN-1 study of SAR445136 is expected to finish as planned, with final patient dosing anticipated in Q3 2022. Preliminary data showed no treatment-related adverse events, and treated patients did not require blood transfusions post-engraftment.

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Sangamo Therapeutics, Inc. (NASDAQ: SGMO) has announced that management will present at the H.C. Wainwright BIOCONNECT Virtual Conference on January 10 at 7:00 a.m. Eastern Time. The presentation can be accessed via the company's website in the Investors and Media section and will be available for viewing post-event. Sangamo focuses on genomic medicine using proprietary zinc finger genome engineering technologies to develop new treatments for diseases lacking adequate options.

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Pfizer (NYSE: PFE) and Sangamo Therapeutics (NASDAQ: SGMO) have released updated follow-up data from the Phase 1/2 Alta study of giroctocogene fitelparvovec, a gene therapy for severe hemophilia A. At 104 weeks, patients in the highest dose cohort exhibited a mean factor VIII activity of 25.4% with no annualized bleeding in the first year post-infusion. However, the Phase 3 AFFINE trial has encountered a clinical hold by the FDA following observations of elevated FVIII levels in treated patients. The ongoing studies aim to evaluate long-term efficacy and safety of this investigational therapy.

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FAQ

What is the current stock price of Sangamo Therapeutics (SGMO)?

The current stock price of Sangamo Therapeutics (SGMO) is $0.7056 as of April 18, 2025.

What is the market cap of Sangamo Therapeutics (SGMO)?

The market cap of Sangamo Therapeutics (SGMO) is approximately 161.5M.

What is the core focus of Sangamo Therapeutics Inc?

The company is dedicated to advancing gene-based therapeutic development and in vivo genome editing to treat serious genetic and neurological diseases.

How does Sangamo generate clinical evidence?

Sangamo employs a rigorous integration of scientific research and clinical trials, including pioneering in vivo human genome editing studies, to validate its therapeutic approaches.

What are the main therapeutic areas in Sangamo's pipeline?

The company’s pipeline includes treatments in neurology, partnered programs in hemophilia A, oncology, neurodegenerative diseases, and additional research on conditions like Fabry disease and inflammatory disorders.

How does Sangamo integrate research and clinical development?

It seamlessly transitions innovative laboratory discoveries into clinical trials, ensuring each therapeutic candidate is rigorously evaluated for safety and efficacy.

What distinguishes Sangamo in the competitive biotech market?

Sangamo’s unique methodology of combining advanced genomic research with practical clinical validations, alongside strategic partnerships, sets it apart in the precision medicine field.

What kind of diseases does Sangamo target with its therapies?

The company targets complex genetic and neurological diseases, focusing on conditions that have traditionally been challenging to treat with conventional therapies.

How is Sangamo’s innovation reflected in its business model?

Its business model is built on a dual strategy of developing in-house therapies and collaborating with external partners to expand its pipeline, thereby integrating research excellence with scalable clinical applications.
Sangamo Therapeutics Inc

Nasdaq:SGMO

SGMO Rankings

SGMO Stock Data

161.45M
219.12M
2.17%
27.49%
12.7%
Biotechnology
Biological Products, (no Disgnostic Substances)
Link
United States
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