Sunshine Biopharma Mice Study for COVID-19 Treatment Progressing as Planned

Rhea-AI Summary

Sunshine Biopharma (SBFM) announced progress in its COVID-19 study at the University of Georgia, focusing on two protease inhibitors aimed at preventing illness in transgenic mice exposed to SARS-CoV-2. Successful results may lead to FDA testing in human patients. The company is also developing Adva-27a, an anticancer drug effective against multidrug-resistant cancer cells, with clinical trials planned at McGill University. The ongoing projects highlight Sunshine Biopharma's commitment to advancing innovative treatment options amidst the COVID-19 pandemic.

Positive

• Progress in COVID-19 mice study with potential FDA submission for human trials.
• Development of Adva-27a shows promise against multidrug-resistant cancer cells.

Negative

• No guaranteed success in ongoing studies which may affect future revenue.
• Significant expenses incurred in research and development may not generate sufficient revenue.

MONTREAL, June 09, 2021 (GLOBE NEWSWIRE) -- Sunshine Biopharma Inc. (OTC PINK: “SBFM”), a pharmaceutical company focused on the research, development and commercialization of oncology and antiviral drugs, today confirmed that its COVID-19 mice study currently underway at the University of Georgia is progressing as planned. The study is assessing the efficacy of two protease inhibitors in preventing transgenic mice challenged with SARS-CoV-2 from progressing to illness and death. Should these studies prove successful, the Company plans to file the data with the FDA and request authorization to do testing in actual COVID-19 patients. Sunshine Biopharma’s protease inhibitor treatment is anticipated to be orally available making it possible for the treatment to be in tablet form which can be taken at home.

“We are moving the project forward as fast as possible, albeit within the constraints of science,” said Dr. Steve Slilaty, CEO of Sunshine Biopharma. “We are optimistic that our research efforts will culminate in a drug that will help turn the page on the pandemic,” he added.

About Sunshine Biopharma

Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) is the causative agent of the ongoing COVID-19 pandemic that has claimed the lives of over 3.7 million people worldwide since it first appeared in December 2019. There are currently no drugs that can effectively arrest replication of the virus in people who have contracted the illness. Sunshine Biopharma has completed the synthesis of four potential inhibitors of PLpro and subsequently identified a lead compound, SBFM-PL4. On February 1, 2021, Sunshine Biopharma entered into an exclusive license agreement with the University of Georgia for two Anti-Coronavirus compounds which the University of Georgia had previously developed and patented. The Company is currently advancing the development of these two compounds in parallel with its own SBFM-PL4 by conducting a transgenic mice study in collaboration with the University of Georgia, College of Pharmacy. The mice being used in the study have been genetically engineered to express the human angiotensin-converting enzyme 2 (hACE2) transmembrane protein in their lungs making them susceptible to lethal infection by SARS-CoV-2. The SARS-CoV-2 virus uses the hACE2 receptor to gain entry into human cells to replicate. The goal of the study is to determine if these protease inhibitors will protect the hACE2-transgenic mice from disease progression and death following infection with SARS-CoV-2. Should these mice studies prove successful, Sunshine Biopharma plans to submit the results to the FDA for authorization to conduct testing on actual COVID-19 patient volunteers in a Phase I clinical trial setting.

In addition, to working on the development of a treatment for COVID-19, Sunshine Biopharma is engaged in the development Adva-27a, a unique anticancer compound. Tests conducted to date have demonstrated the effectiveness of Adva-27a at destroying Multidrug Resistant Cancer Cells, including Pancreatic Cancer cells, Small-Cell Lung Cancer cells, Breast Cancer cells, and Uterine Sarcoma cells. Clinical trials for Pancreatic Cancer indication are planned to be conducted at McGill University’s Jewish General Hospital in Montreal, Canada. Sunshine Biopharma is owner of all patents and intellectual property pertaining to Adva-27a.

Safe Harbor Forward-Looking Statements

This press release may contain forward looking statements which are based on current expectations, forecasts, and assumptions that involve risks as well as uncertainties that could cause actual outcomes and results to differ materially from those anticipated or expected, including statements related to the amount and timing of expected revenues statements related to our financial performance, expected income, distributions, and future growth for upcoming quarterly and annual periods. These risks and uncertainties are further defined in filings and reports by the Company with the U.S. Securities and Exchange Commission (SEC). Actual results and the timing of certain events could differ materially from those projected in or contemplated by the forward-looking statements due to a number of factors detailed from time to time in our filings with the SEC. Among other matters, the Company may not be able to sustain growth or achieve profitability based upon many factors including but not limited to general stock market conditions. Reference is hereby made to cautionary statements set forth in the Company's most recent SEC filings. We have incurred and will continue to incur significant expenses in our expansion of our existing as well as new service lines noting there is no assurance that we will generate enough revenues to offset those costs in both the near and long term. Additional service offerings may expose us to additional legal and regulatory costs and unknown exposure(s) based upon the various geopolitical locations we will be providing services in, the impact of which cannot be predicted at this time.

For Additional Information Contact:
Camille Sebaaly, CFO
Sunshine Biopharma Inc.
Direct Line: 514-814-0464
camille.sebaaly@sunshinebiopharma.com
www.sunshinebiopharma.com

FAQ

What are the recent developments for Sunshine Biopharma (SBFM) in COVID-19 research?

Sunshine Biopharma is conducting a mice study to assess the efficacy of protease inhibitors against SARS-CoV-2, with potential plans to file for FDA approval for human testing.

What is the status of Adva-27a in cancer treatment by Sunshine Biopharma (SBFM)?

Adva-27a is being developed as an anticancer treatment, with effectiveness demonstrated against multidrug-resistant cancer cells. Clinical trials are planned at McGill University.

When did Sunshine Biopharma (SBFM) enter licensing agreements for anti-coronavirus compounds?

Sunshine Biopharma entered into an exclusive license agreement with the University of Georgia on February 1, 2021, for two anti-coronavirus compounds.

What challenges does Sunshine Biopharma (SBFM) face in its drug development?

The company faces significant expenses in research and development, with no assurance of generating enough revenue to offset these costs.