Sunshine Biopharma Completes the Synthesis of Four Potential Inhibitors of Coronavirus Protease

Rhea-AI Summary

Sunshine Biopharma (OTC PINK:SBFM) has successfully synthesized four potential inhibitors targeting the Coronavirus protease, a crucial component for the virus's replication. This advancement stems from a recently filed patent for small molecules aimed at treating Coronavirus infections, including COVID-19. The next steps involve analyzing the binding affinity of these compounds to the SARS-CoV-2 papain-like protease, selecting a lead candidate for further development. Sunshine is also advancing its anticancer drug, Adva-27a, which has shown effectiveness against multidrug-resistant cancer cells.

Positive

• Completion of synthesis for four potential Coronavirus protease inhibitors.
• Advancement towards evaluating binding affinity for drug development.
• Potential treatment for COVID-19 could be commercially viable.

Negative

• None.

MONTREAL, QC / ACCESSWIRE / August 25, 2020 / Sunshine Biopharma Inc. (OTC PINK:SBFM), a pharmaceutical company focused on the research, development and commercialization of oncology and antiviral drugs today announced that it has completed the synthesis of four different potential inhibitors of Coronavirus protease. These compounds are based on the technology described in the Company's recently filed patent application covering small molecules which can be used to treat Coronavirus infections, including SARS-CoV-2 the causative agent of COVID-19. Next, Sunshine will evaluate the binding affinity of these molecules to the SARS-CoV-2 papain-like protease (PLpro), one of two virus encoded proteases essential for viral replication. In addition to cleaving the virus encoded polyprotein at three different sites to generate mature virus proteins, PLpro also cleaves certain host proteins resulting in suppression of the innate immune response thereby allowing the virus to multiply unhindered. Based on the binding affinity results, Sunshine will select a lead compound for further Anti-Coronavirus drug development.

About Sunshine Biopharma
Sunshine Biopharma is a pharmaceutical company focused on the research, development, and commercialization of oncology and antiviral drugs. In addition, to working on the development of a treatment for COVID-19, Sunshine biopharma is engaged in the development Adva-27a, a unique anticancer compound. Tests conducted to date have demonstrated the effectiveness of Adva-27a at destroying Multidrug Resistant Cancer Cells, including Pancreatic Cancer cells, Small-Cell Lung Cancer cells, Breast Cancer cells, and Uterine Sarcoma cells. Clinical trials for Pancreatic Cancer indication are planned to be conducted at McGill University's Jewish General Hospital in Montreal, Canada. Sunshine Biopharma is owner of all patents and intellectual property pertaining to Adva-27a and the Coronavirus protease inhibitors under development.

Safe Harbor Forward-Looking Statements
To the extent that statements in this press release are not strictly historical, including statements as to revenue projections, business strategy, outlook, objectives, future milestones, plans, intentions, goals, future financial conditions, future collaboration agreements, the success of the Company's development, events conditioned on stockholder or other approval, or otherwise as to future events, such statements are forward-looking, and are made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. The forward-looking statements contained in this release are subject to certain risks and uncertainties that could cause actual results to differ materially from the statements made.

For Additional Information:
Sunshine Biopharma, Inc.
Camille Sebaaly
CFO
Direct Line: 514-814-0464
camille.sebaaly@sunshinebiopharma.com
www.sunshinebiopharma.com

SOURCE: Sunshine Biopharma Inc.

View source version on accesswire.com:
https://www.accesswire.com/603154/Sunshine-Biopharma-Completes-the-Synthesis-of-Four-Potential-Inhibitors-of-Coronavirus-Protease

FAQ

What recent development has Sunshine Biopharma (SBFM) announced regarding COVID-19?

Sunshine Biopharma has completed the synthesis of four potential inhibitors of the Coronavirus protease.

How will Sunshine Biopharma evaluate its synthesized inhibitors?

The company will evaluate the binding affinity of these inhibitors to the SARS-CoV-2 papain-like protease.

What is Adva-27a and its significance for Sunshine Biopharma (SBFM)?

Adva-27a is an anticancer compound developed by Sunshine Biopharma, showing effectiveness against multidrug-resistant cancer cells.

What is the stock symbol for Sunshine Biopharma?

The stock symbol for Sunshine Biopharma is SBFM.

What future plans does Sunshine Biopharma have for its COVID-19 treatment?

Sunshine plans to select a lead compound for further anti-Coronavirus drug development based on binding results.