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Repare Therapeutics Inc. Common Shares - RPTX STOCK NEWS

Welcome to our dedicated page for Repare Therapeutics Common Shares news (Ticker: RPTX), a resource for investors and traders seeking the latest updates and insights on Repare Therapeutics Common Shares stock.

Repare Therapeutics Inc. (RPTX) is a pioneering precision medicine oncology company dedicated to the advancement of synthetic lethality-based therapies for cancer patients. The company's mission is to develop innovative oncology drugs that specifically target the vulnerabilities of tumor cells in genetically defined patient populations.

Repare utilizes an integrated approach combining insights from multiple fields of cell biology, including DNA repair and synthetic lethality. Their proprietary platform employs a high-throughput, CRISPR-enabled gene editing target discovery method alongside high-resolution protein crystallography, computational biology, and clinical informatics.

Backed by prominent global healthcare investors such as Versant Ventures and MPM Capital, Repare Therapeutics is poised at the forefront of cancer treatment innovation. The company’s robust research and development pipeline is aimed at delivering groundbreaking treatments designed to improve patient outcomes.

Repare Therapeutics has made significant strides in the oncology field, participating in numerous clinical trials and forming strategic partnerships to expedite the delivery of effective cancer therapies. With a core focus on precision oncology, the company aims to address the unmet medical needs of cancer patients worldwide. The majority of its revenue is currently derived from its operations in Canada.

For more detailed information and the latest updates, you can visit their official website at www.reparerx.com.

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Repare Therapeutics presented promising results for its drug RP-3500 in a Phase 1/2 trial, demonstrating a 75% clinical benefit rate (CBR) in ovarian cancer patients, with a 25% overall response rate (ORR) and a median progression-free survival (mPFS) of 35 weeks. For solid tumors, a 43% CBR was noted, indicating robust activity across genotypes. The drug also showed favorable safety profiles, with manageable side effects. Further data on combination trials with PARP inhibitors are expected later this year, enhancing its development strategy.

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Repare Therapeutics Inc. (Nasdaq: RPTX) announced comprehensive Phase 1 monotherapy data from its ongoing Phase 1/2 TRESR trial for RP-3500, an ATR inhibitor, to be presented at the 2022 AACR Annual Meeting in New Orleans from April 8-13, 2022. An oral presentation is scheduled for April 11, 2022, at 3:05 PM CT, led by Dr. Timothy Yap. The company will host a conference call to discuss these findings on the same day at 6:30 PM ET. Repare aims to highlight RP-3500's therapeutic potential and ongoing development plans.

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Repare Therapeutics (NASDAQ: RPTX) announced that it will present clinical data from its Phase 1/2 TRESR trial of RP-3500 at the upcoming 2022 AACR Annual Meeting in New Orleans. The oral presentation, focusing on genomic determinants of response to RP-3500 in patients with DNA damage repair mutant tumors, is scheduled for April 11, 2022. Additionally, a poster will be presented on the SNiPDx panel, aimed at detecting DNA repair gene losses in tumor samples, on April 12, 2022. Repare’s SNIPRx® platform supports its precision therapeutics development.

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Repare Therapeutics Inc. announced positive findings from its Phase 1/2 TRESR clinical trial of RP-3500, a selective ATR inhibitor for treating solid tumors. Data presented at the ESMO TAT Congress confirmed that RP-3500 is well tolerated, with a recommended Phase 2 dose of 160mg 3 days on/4 days off. Anemia was the primary reported toxicity, impacting less than 25% of patients.

The company plans to share updated data from 120 patients in the first half of the year, reinforcing expectations for the therapeutic potential of RP-3500.

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Repare Therapeutics Inc. (RPTX) reported its financial results for Q4 and full year 2021, highlighting key advancements in its precision oncology pipeline. Notable progress includes the initiation of the RP-6306 program and the RP-3500 Phase 2 trial for solid tumors. By December 31, 2021, cash reserves stood at $341.9 million, sufficient for operations through 2023. R&D expenses surged to $90 million, reflecting increased development costs. The net loss was $106.9 million, or $2.83 per share, compared to $53.4 million, or $2.66 per share in 2020.

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Repare Therapeutics Inc. (NASDAQ: RPTX) announced participation in two virtual investor conferences in February 2022. The Guggenheim Oncology Conference is scheduled for February 10, 2022 at 2:00 p.m. ET, while the 11th Annual SVB Leerink Global Healthcare Conference will take place on February 18, 2022 at 3:00 p.m. ET. Live webcasts for both presentations will be available on the Company's website, with archiving for 90 days. Repare specializes in precision oncology, utilizing its SNIPRx® platform for targeted cancer therapies.

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Repare Therapeutics (RPTX) provided a corporate update, highlighting significant advancements in 2021 and expectations for 2022. The company reported positive Phase 1 data for RP-3500 and initiated patient enrollment for combination trials. Key milestones include the upcoming Phase 2 TRESR trial for RP-3500, data releases for RP-3500 and RP-6306, and IND-enabling studies for a Polθ inhibitor. Repare ended Q3 2021 with approximately $268.2 million in cash, facilitating operations through 2023. The company will present at the J.P. Morgan Healthcare Conference on January 12, 2022.

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Repare Therapeutics has appointed Philip Herman as its EVP Commercial & New Product Development, bringing over 20 years of experience in the pharmaceutical and biotech industries. The company is focused on advancing its lead products, RP-3500 and RP-6306, in the precision oncology space. Herman's prior role as CCO at Y-mAbs Therapeutics included launching DANYELZA®. The company aims for a significant transition from clinical stages to commercialization in 2022, enhancing their integrated product development and launch strategies.

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Repare Therapeutics Inc. (Nasdaq: RPTX), a clinical-stage precision oncology company, announced that Lloyd M. Segal, CEO, will present virtually at the 40th Annual J.P. Morgan Healthcare Conference on January 12, 2022 at 3:45 p.m. ET. The presentation will be accessible via the Company's website, with a replay available for 30 days. Repare's innovative Synthetic Lethality approach aims to develop targeted cancer therapies, including lead candidate RP-3500, currently in Phase 1/2 clinical development.

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Repare Therapeutics (NASDAQ: RPTX) has commenced its Phase 1 clinical trial for RP-6306, a pioneering small molecule targeting PKMYT1, combined with gemcitabine for treating advanced solid tumors. The trial, named MAGNETIC, aims to dose approximately 104 patients selected based on genomic alterations. The primary goals include determining the maximum tolerated dose and evaluating preliminary anti-tumor activity. This milestone follows ongoing developments in Repare's precision oncology pipeline, which features several innovative therapeutic candidates.

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FAQ

What is the current stock price of Repare Therapeutics Common Shares (RPTX)?

The current stock price of Repare Therapeutics Common Shares (RPTX) is $1.32 as of December 20, 2024.

What is the market cap of Repare Therapeutics Common Shares (RPTX)?

The market cap of Repare Therapeutics Common Shares (RPTX) is approximately 56.1M.

What does Repare Therapeutics Inc. specialize in?

Repare Therapeutics Inc. specializes in developing precision oncology drugs that target specific vulnerabilities in tumor cells using synthetic lethality-based therapies.

What unique technology does Repare Therapeutics use?

Repare Therapeutics employs a proprietary CRISPR-enabled gene editing target discovery method combined with high-resolution protein crystallography, computational biology, and clinical informatics.

Who are the major investors backing Repare Therapeutics?

Repare Therapeutics is supported by leading global healthcare investors, including Versant Ventures and MPM Capital.

Where does Repare Therapeutics derive its maximum revenue from?

The company derives the majority of its revenue from Canada.

What is the focus area of Repare Therapeutics' research and development?

Repare Therapeutics focuses its R&D on precision oncology, particularly targeting synthetic lethality-based therapies for cancer patients.

Where can I find more information about Repare Therapeutics?

More information can be found on their official website at www.reparerx.com.

How does Repare Therapeutics identify drug targets?

Repare identifies drug targets using their proprietary, high-throughput CRISPR-enabled gene editing platform.

What fields of cell biology does Repare Therapeutics integrate insights from?

Repare integrates insights from DNA repair and synthetic lethality in their research and development efforts.

What is the significance of synthetic lethality in Repare Therapeutics' approach?

Synthetic lethality allows Repare Therapeutics to develop drugs that target specific genetic vulnerabilities in tumor cells, making treatments more effective for genetically defined patient populations.

Is Repare Therapeutics involved in clinical trials?

Yes, Repare Therapeutics is actively participating in numerous clinical trials to expedite the delivery of effective cancer therapies.

Repare Therapeutics Inc. Common Shares

Nasdaq:RPTX

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56.11M
38.71M
0.95%
83.73%
1.43%
Biotechnology
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