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ReNeuron Group presented preclinical data revealing its CustomEx exosome platform's superior drug delivery capabilities compared to conventional HEK-derived exosomes. Key findings include a minimum 10-fold increase in cellular uptake across three cell types, with an 18-fold increase in endothelial cells. Notably, siRNA-loaded CustomEx exosomes achieved a 600% improvement in delivery to target cells. This technology positions ReNeuron favorably for potential partnerships and aligns with growth in the RNA therapeutic market.
ReNeuron announced the restart of its nine-patient Phase IIa extension study, previously halted due to an eye infection case. With five patients remaining, two are set for treatment this October. Initial data is expected by March 2022, crucial for potential partnerships. The company maintains a valuation of £190m, supported by cash reserves of £22.2m as of March 2021, projected to sustain operations through Q4 FY23. The management anticipates possible eye therapy deals and exosome collaborations that could cover pivotal trial costs.