Regencell Bioscience’s Investigational Liquid-Formula RGC-COV19TM Shows Effectiveness Through Its Enrolled Patients in Eliminating Mild to Moderate COVID-19 Symptoms within the 6-day Treatment Period in its EARTH Efficacy Trial
Regencell Bioscience Holdings Limited (NASDAQ: RGC) announced positive results from its EARTH efficacy trial evaluating RGC-COV19TM, a COVID-19 treatment. Of the 37 patients, 97.3% eliminated all symptoms, except for sensory dysfunction and occasional cough, within six days. Notably, 83.8% experienced symptom relief after just one dose. The trial indicated no adverse side effects, and no patients were hospitalized or died during the study. These findings highlight the potential of RGC-COV19TM for broader COVID-19 treatment applications.
- 97.3% of patients eliminated all symptoms within 6 days.
- 83.8% of patients reported symptom elimination after one dose.
- No adverse side effects reported during the trial.
- No patients were hospitalized or died during the study.
- None.
-
36 out of 37 COVID-19 patients treated in the trial, representing approximately
97.3% of the patients, reported they had all symptoms eliminated within the 6-day treatment period save for loss or reduced sense of taste and smell (“Sensory Dysfunction”) and occasional cough. The highest number of different symptoms reported for any one individual was 14. - 15 out of the 36 patients experienced Sensory Dysfunction prior to receiving treatment. Among those 15 patients, 5 recovered their sensory functions while the remaining 10 showed improvements at the end of the 6-day treatment period.
-
31 out of 37 COVID-19 patients, representing approximately
83.8% of patients, reported the elimination of one or more symptoms after taking 1 full dose of RGC-COV19TM (1 day of treatment) with the largest number of symptoms eliminated after 1 day of treatment being 7. - Out of the 37 patients, 9 patients experienced a combination of dyspnea (difficulty breathing) and persistent chest pain. 6 of these 9 patients no longer experienced difficulty breathing and/or persistent chest pain after 1 full dose of RGC-COV19TM.
- All 23 patients who started taking RGC-COV19TM within 3 days from symptoms onset took an average of approximately 3.2 days for the elimination of all symptoms, save for Sensory Dysfunction and occasional cough.
- All 14 patients who started taking RGC-COV19TM between 4 to 5 days from symptoms onset took an average of approximately 3.6 days for the elimination of all symptoms, save for Sensory Dysfunction and occasional cough.
“The results of EARTH mark an important journey for the Company in its goal to save and improve lives of patients all around the world. As COVID-19 cases continue to rise globally in 2022, there is an urgency to find a holistic approach towards treating COVID-19. By establishing Regencell Asia and through EARTH’s preliminary findings, we hope the process of finding an alternative, natural treatment for COVID-19 will be accelerated. These results highlight the potential of offering a natural and holistic treatment for COVID-19,” said
About EARTH Efficacy Trial
The primary objective of EARTH is to evaluate and assess the efficacy of Regencell Bioscience’s TCM – RGC-COV19TM (
EARTH was a non-blinded efficacy trial conducted from
Based on the above-mentioned criteria, patients who were asymptomatic were rejected and 37 random individuals eventually qualified for enrolment and were enrolled. The enrolled patients were between the ages of 5 to 61 and of different races, ethnic backgrounds and socioeconomic backgrounds. 23 individuals were based in
In conducting EARTH, Regencell Asia set a maximum of 6 days of treatment per patient. Enrolled patients were required to report their COVID-19 symptoms every day according to 3 severity categories (mild, moderate, severe) and the list contained symptoms such as fever, fatigue, cough, sore throat, runny nose, headache, nausea, feeling hot, chills, drowsy, shortness of breath, persistent chest pain or pressure, muscle ache and abdominal discomfort. Patients were also requested to identify any other symptoms that they were experiencing. Each patient received 2 days of treatment progressively while a reverse transcription polymerase chain reaction (RT-PCR) test for patients in
Whenever a patient’s RT-PCR test result turned negative or patients no longer had any COVID-19 symptoms (save for Sensory Dysfunction or occasional cough) within the 6-day treatment period, the treatment ended. While receiving the TCM treatment, 3 of them were not vaccinated, 3 were partially vaccinated and 31 were fully vaccinated. At the end of the treatment, the total number of patients whose symptoms were completely eliminated within the 6-day treatment period, save for Sensory Dysfunction and occasional cough, were recorded to determine the efficacy.
About EARTH’s Results
Efficacy of complete symptoms elimination within the 6-day treatment period
Out of the 37 COVID-19 patients, 36 patients had all symptoms eliminated, save for Sensory Dysfunction and occasional cough, within the 6-day treatment period. Our efficacy trial showed that after taking RGC-COV19TM,
Out of the 36 patients, the number of days it took for all symptoms to be eliminated, save for Sensory Dysfunction and occasional cough, within the 6-day treatment period, was 1 day = 6 patients, 2 days = 7 patients, 3 days = 5 patients, 4 days = 11 patients, 5 days = 4 patients, and 6 days = 3 patients.
Symptoms elimination after 1 full dose of RGC-COV19TM
31 out of 37 COVID-19 patients, representing approximately
Out of the 23 patients from
Taking the treatment within 3 days from symptoms onset vs within 4 to 5 days from symptoms onset
Further analysis showed that the 23 patients who started taking RGC-COV19TM within 3 days from symptoms onset took an average of approximately 3.2 days for the elimination of all symptoms, save for Sensory Dysfunction and occasional cough, whereby the maximum number of different symptoms reported by any one individual was 14 and the average number of different symptoms reported was 5.
The remaining 14 patients who started taking RGC-COV19TM between 4 to 5 days from symptoms onset took an average of approximately 3.6 days for the elimination of all symptoms, save for Sensory Dysfunction and occasional cough, whereby the maximum number of different symptoms reported by any one individual was 13 and the average number of symptoms reported was 7.
Vaccination status
The 3 patients who were not vaccinated reported an average of 3 symptoms each and all 3 patients took an average of approximately 2.3 days for symptoms to be eliminated. The 3 patients who were partially vaccinated reported an average of 3 symptoms each and took an average of approximately 3.3 days for all symptoms to be eliminated, save for Sensory Dysfunction. 1 of these 3 patients tested negative RT-PCR after 4 days of treatment. The remaining patients who were fully vaccinated reported an average number of 6 symptoms each and these patients took an average of approximately 3.5 days for all symptoms to be eliminated, save for Sensory Dysfunction and occasional cough. All patients who were vaccinated either received a single dose, double dose, or a combination of vaccine from Pfizer-BioNTech, Moderna, AstraZeneca, Sinovac-CoronaVac and/or Johnson & Johnson’s Janssen.
High-risk patients
Out of the 37 patients, 9 patients experienced a combination of dyspnea (difficulty breathing) and persistent chest pain. 6 of these 9 patients no longer experienced difficulty breathing and/or persistent chest pain after 1 full dose of RGC-COV19TM.
No adverse side effects
Based on the patients’ self-reported data, there were no worsening of symptoms during and after consuming RGC-COV19TM and none of the patients experienced any unknown adverse side effects.
No treatment emergent adverse events
Among the 3 patients with comorbidities such as systemic lupus erythematosus (SLE), asthma and cancer, there were no treatment emergent adverse events and no discontinuation of RGC-COV19TM due to adverse results.
Death/Hospitalization
At the end of the EARTH efficacy trial, none of the patients was hospitalized and there was no death. The efficacy of RGC-COV19TM was not affected by timing of symptom onset or underlying risk factor. Results were consistent across all ages, gender, races and ethnicity demographic among the enrolled patients.
More about EARTH
There are hundreds of millions of individuals who have been diagnosed with COVID-19 around the world, and some experience post-COVID symptoms such as extreme tiredness (fatigue), shortness of breath, problems with memory and concentration (brain fog), heart palpitations, dizziness, chest pain or tightness, joint pain which are now being classified as long-COVID symptoms.
As long-COVID symptoms have substantial effects on individuals’ quality of life and work capability, Regencell Asia is in the midst of conducting its studies for long-COVID patients using a natural and holistic formula - RGC-COV19TM (RGCA-LCV01).
About RGC-COV19TM
RGC-COV19TM (RGCA-CV01) is an investigational, natural, orally administered liquid formula which aims to reduce and eliminate COVID-19 symptoms.
RGC-COV19TM can be taken safely for two to three weeks. In conducting EARTH, the treatment was limited to 6 days in order to evaluate its efficacy in reducing and eliminating COVID-19 symptoms.
Regencell began its investigational approach towards COVID-19 treatment when a friend of Regencell contracted COVID-19 in
Study results showed that the treatment was effective. As Regencell has a goal to save lives, improve patients’ well-being and address unmet needs in the market, Regencell wants to make its natural and holistic treatment available to people in need.
From
RGC-COV19TM uses natural ingredients to stimulate the body’s own healing mechanism and the medicine effectively reduces COVID-19 symptoms such as fever, fatigue, cough, sore throat, runny nose, headache, nausea, chills, drowsiness, shortness of breath, persistent chest pain and muscle ache as the medicine works to (i) reduce and clear the mucus and phlegm from the upper respiratory system; (ii) dispel exterior viral pathogen via heavy sweats, urine and excrement; (iii) clear endogenous and liver heat; (iv) detox the liver; and (v) improving body circulation.
By applying the TCM Practitioner’s “Sik-Kee Au TCM Brain Theory®”, RGC-COV19TM removes blood clots from the brain hence restoring the patient's various brain functions.
RGC-COV19TM (RGCA-CV01) is administered at 1 dose of RGCA-CV01-1Na (approximately 230ml) and 1 dose of RGCA-CV01-2Da (approximately 230ml) each time, with 1 dose of RGCA-CV01-1Na to be taken starting from the night of the first day of treatment and 1 dose of RGCA-CV01-2Da to be taken after lunch the next day, until symptoms are eliminated.
About
For more than 30 years, the TCM Practitioner whom
Both
Since its listing,
Forward-looking Statements
This press release contains “forward‐looking statements” within the meaning of applicable laws, including
View source version on businesswire.com: https://www.businesswire.com/news/home/20220216005895/en/
Investor Relations
ir@rgcbio.com
+852 2155 0823
Source:
FAQ
What were the results of Regencell's EARTH trial for RGC-COV19?
How effective is RGC-COV19 after one dose?
Did the EARTH trial report any side effects from RGC-COV19 treatment?
What is the significance of the EARTH trial results for Regencell (RGC)?