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Arcus Biosciences, Inc. (NASDAQ: RCUS) is a cutting-edge, clinical-stage biopharmaceutical company dedicated to developing innovative immunotherapies for cancer treatment. Founded in 2015 by experienced researchers from the biotechnology and pharmaceutical sectors, Arcus is based in the San Francisco Bay Area, a hub for biotechnological innovation.
Arcus Biosciences focuses on leveraging insights in immunology to create new cancer therapeutics. The company is particularly known for its work on the ATP-adenosine pathway, a significant driver of immunosuppression in the tumor microenvironment. Their aim is to optimize small-molecule immuno-oncology product candidates that could revolutionize cancer treatment.
Arcus has a robust product pipeline that includes several promising candidates such as Domvanalimab, Etrumadenant, AB598, and Casdatifan. These drugs target different aspects of the immune system to either modulate cellular processes in cancer or directly combat tumor growth.
Significant achievements include successful clinical trials for treating various types of cancers, including lung, colorectal, and pancreatic cancers. The company operates through a single segment focused on the development and commercialization of its immunotherapies.
Arcus prides itself on maintaining an internal team of highly skilled professionals rather than outsourcing its research and development efforts. This approach ensures the highest quality and innovation in their drug discovery process.
With ongoing partnerships and collaborations, notably with Gilead Sciences, Arcus is well-positioned to bring its innovative therapies to market, providing new hope for patients with cancer.
Arcus Biosciences (NYSE:RCUS) announced the granting of stock options to twelve new employees, totaling 180,200 shares at an exercise price of $30.90, the closing price on April 8, 2021. This action follows the guidelines of the 2020 Inducement Plan approved by the Board of Directors. Arcus is focused on developing innovative cancer therapies, with five molecules currently in clinical development targeting various cancers, including prostate and pancreatic. Notable candidates include Etrumadenant and AB680, which are in different stages of trials.
Arcus Biosciences (NYSE:RCUS) announced the grant of stock options to fourteen new employees, totaling 157,300 shares at an exercise price of $34.45, the closing price on March 23, 2021. This grant aligns with the Company’s 2020 Inducement Plan approved by the Board of Directors in January 2020. The Company is focused on developing innovative cancer therapies and has five molecules in clinical development, including Etrumadenant and Zimberelimab, addressing unmet medical needs in various cancer types.
Arcus Biosciences, Inc. (NYSE: RCUS) has granted stock options to five new employees, totaling 160,800 shares at an exercise price of $31.49, as per its 2020 Inducement Plan. This move follows NYSE guidelines and aims to incentivize new talent. The company focuses on developing innovative cancer therapies, with five molecules currently in clinical stages, including Etrumadenant, AB680, and Domvanalimab. These developments target significant unmet medical needs in various cancer types.
Arcus Biosciences, Inc. (NYSE:RCUS) has granted stock options for a total of 31,400 shares to four new employees at an exercise price of $33.28, based on the closing price from February 23, 2021. This grant is part of the Company's 2020 Inducement Plan, approved by the Board of Directors. Arcus specializes in oncology with five clinical-stage molecules, including Etrumadenant, AB680, and Domvanalimab. The company is focused on developing innovative therapies to address significant unmet needs in cancer treatment.
Arcus Biosciences (RCUS) reported a strong financial position with $735 million in cash and a recent $220 million equity investment from Gilead. The company is advancing its pipeline, including starting registrational trials for domvanalimab and expanding clinical studies for AB680. Collaboration revenues increased to $77.5 million in 2020 from $15 million in 2019. However, R&D expenses rose significantly to $159.3 million, contributing to a net loss of $122.9 million for the year. Despite losses, positive clinical developments and strategic partnerships position Arcus for future growth.
Arcus Biosciences (NYSE:RCUS) announced upcoming presentations at key virtual investor conferences. Management will present at the 10th Annual SVB Leerink Global Healthcare Conference on February 26, Cowen's 41st Annual Health Care Conference on March 2, and Barclays Global Healthcare Conference on March 10. Investors can access live audio webcasts on the Arcus website, with replays available for at least two weeks post-event. Arcus focuses on developing innovative cancer therapies, with multiple drug candidates in clinical trials addressing significant unmet needs.
Arcus Biosciences (NYSE:RCUS) announced the grant of stock options to five new employees, totaling 126,200 shares at an exercise price of $41.39, the closing price on February 8, 2021. This move is part of the Company’s 2020 Inducement Plan, aimed at attracting talent. Arcus is focused on developing cancer therapies, with four molecules in clinical trials, including Etrumadenant and AB680. The company emphasizes its commitment to addressing significant unmet needs in oncology while leveraging a robust pipeline of innovative treatments.
Arcus Biosciences (NYSE:RCUS) announced that Gilead Sciences will increase its ownership stake in the company from approximately 13% to 19.5% by purchasing 5,650,000 shares at $39.00 each. This investment highlights the partnership's strength and supports the acceleration of Arcus's clinical development plans for its four clinical-stage molecules, including AB680 for metastatic pancreatic cancer. Following this financing, Arcus expects to fund its operations through at least 2023. The ongoing collaboration is crucial for developing next-generation cancer therapies.
Arcus Biosciences (NYSE:RCUS) announced the grant of stock options to five new employees, totaling 165,300 shares at an exercise price of $38.19, based on the January 25, 2021 closing price. This grant was made under the 2020 Inducement Plan approved by the Board of Directors. The company focuses on developing innovative oncology therapies with four clinical-stage molecules, including Etrumadenant, AB680, Domvanalimab, and Zimberelimab, targeting various cancer types, illustrating its commitment to addressing significant unmet medical needs in oncology.
Arcus Biosciences (NYSE:RCUS) presented preliminary data from the ARC-8 Phase 1/1b study at ASCO 2021, focusing on the safety and efficacy of AB680, a small-molecule CD73 inhibitor, in metastatic pancreatic cancer. The study involved 19 patients receiving AB680, nab-paclitaxel, and gemcitabine. No significant additive toxicity was observed, although one patient experienced Grade 2 autoimmune hepatitis. Preliminary efficacy showed that 88% of patients had lesion shrinkage, with an overall response rate of 41%. AB680 was selected for expansion at 100mg every two weeks, showing potential for advancing treatment in this challenging cancer type.