PureTech Health plc American Depositary Shares - PRTC STOCK NEWS

PureTech Health announced results from a Phase 2 study of LYT-100 (deupirfenidone) in patients with post-acute “Long” COVID, revealing no treatment effect. However, the study reaffirmed LYT-100's strong safety and tolerability profile. PureTech will not pursue further studies in this patient population but will focus on initiating registration-enabling studies for LYT-100 in idiopathic pulmonary fibrosis (IPF) later this month, leveraging previously established efficacy of pirfenidone. The study involved 177 patients and showed meaningful improvements in walking distance for both treatment and placebo groups.

Vedanta Biosciences, a clinical-stage company, announced that CEO Bernat Olle will speak at the JMP Securities Life Sciences Conference on June 16, 2022, at 11:30 a.m. ET in New York. The company focuses on developing a new category of oral therapies based on defined bacterial consortia from the human microbiome to treat conditions such as C. difficile infection and inflammatory bowel diseases. Vedanta controls a significant patent portfolio and boasts expertise in bacterial consortium design, with a belief in their pioneering research in this emerging field.

PureTech Health plc announced that Matt Franklin will join Akili Interactive Labs as President and Chief Operating Officer on June 21, 2022. Franklin, a life sciences expert with over 20 years of experience, has previously held significant roles at Exact Sciences, Thrive Earlier Detection Corp, and Foundation Medicine. His appointment aims to drive Akili's growth and prepare for the commercialization of its cognitive treatment product, EndeavorRx®, focusing on enhancing operational efficiency and strategic marketing.

PureTech Health (Nasdaq: PRTC, LSE: PRTC) announced participation in a fireside chat at the Jefferies Healthcare Conference on June 9, 2022, at 9:30 AM EDT in New York City. Presenters include Bharatt Chowrira, Ph.D., J.D., and Julie Krop, M.D. The discussion will cover the company’s innovative approaches to treating serious diseases, supported by a robust pipeline of 27 therapeutic candidates. A webcast of the presentation will be available through their investor website.

PureTech Health, in partnership with Roblox, aims to enhance patient experiences through innovative digital solutions. The collaboration introduces a Roblox rewards exchange linked to Akili’s EndeavorRx, the first FDA-cleared prescription video game for children with ADHD. This partnership seeks to integrate cognitive treatments into daily life, leveraging Roblox's vast user base of over 55 million players. Both companies focus on redefining patient engagement and improving cognitive health through interactive experiences.

PureTech Health (Nasdaq: PRTC, LSE: PRTC) announced new findings from its Founded Entity, Vedanta Biosciences, at the Digestive Disease Week 2022. Key data from the VE303 Phase 2 CONSORTIUM study showed VE303 effectively prevented Clostridioides difficile infection recurrence in high-risk patients, achieving a 31.7% absolute risk reduction. The VE303 high-dose group noted an 80% reduction in recurrence odds. Additionally, safety analyses of VE202 and VE818 indicated robust colonization and increased production of beneficial bile acids. These insights pave the way for future clinical trials.

Vedanta Biosciences presented key findings from multiple clinical studies on their defined bacterial consortia at Digestive Disease Week 2022. The Phase 2 CONSORTIUM study showed that VE303 significantly reduced recurrent Clostridioides difficile infections, achieving a 31.7% absolute risk reduction compared to placebo. Further analysis indicated that higher doses resulted in improved strain colonization and lower recurrence rates. Additionally, safety results for VE202 and VE818 from Phase 1 studies were promising, showing good tolerability and effective colonization in healthy volunteers.

PureTech Health plc (LSE:PRTC, Nasdaq:PRTC) has announced that CFO George Farmer, Ph.D., will present at the UBS Global Healthcare Conference on May 24, 2022, at 10:45am EDT. The presentation will be available via webcast on the company's investor relations website. PureTech is focused on developing biotherapeutics for serious diseases and has a pipeline of 27 therapeutics, including two with FDA clearance and European marketing authorization. The company emphasizes innovation in immunology and drug development.

PureTech Health presented new data on LYT-100 at the American Thoracic Society 2022 International Conference, highlighting its improved tolerability profile compared to pirfenidone. The Phase 1 study showed a 38% reduction in adverse events with LYT-100 in healthy older adults. This data supports upcoming registration studies in idiopathic pulmonary fibrosis (IPF), with topline results expected by the end of 2023. Using a 505(b)(2) pathway, PureTech aims to evaluate higher doses to enhance efficacy while retaining safety profiles.