PureTech Health plc American Depositary Shares - PRTC STOCK NEWS

PureTech Health plc (LSE: PRTC, Nasdaq: PRTC) is set to announce its half-yearly results for the six months ending June 30, 2022, on August 25, 2022. The Company will host a presentation and conference call for analysts and shareholders at 9:00 am EDT. PureTech is focused on developing innovative therapeutics for serious diseases, boasting a diverse pipeline of 27 therapeutic candidates, including two with FDA clearance and European marketing authorization.

PureTech Health's Founded Entity, Akili Interactive Labs, has launched a pivotal Phase 3 study of SDT-001, a digital treatment aimed at improving attention in children with ADHD in Japan. This trial follows a successful Phase 2 study showing enhanced attention compared to standard treatments. Approximately 150 participants aged 6-17 will enroll in multiple sites, with results expected in 2H2023. The treatment leverages video game technology designed to engage cognitive functions. Akili's products are already FDA-cleared and CE-marked in the U.S. and Europe for similar indications.

PureTech Health plc (Nasdaq: PRTC) reported positive results from a study of Akili's digital therapeutic AKL-T01 for cognitive dysfunction in patients with Systemic Lupus Erythematosus (SLE). Conducted with 60 participants, the study showed significant improvements in motor speed and executive functions. The EVO™ Monitor also demonstrated its potential for rapid mobile cognitive assessment. This technology could enhance treatment options for approximately 1.5 million SLE patients in the U.S., where cognitive dysfunction affects 20% to 80% of them.

PureTech Health (LSE: PRTC, Nasdaq: PRTC) announced nominees for the board of directors for its Founded Entity, Akili Interactive, following its merger with Social Capital Suvretta Holdings Corp. I (Nasdaq: DNAA). The board will include industry leaders such as BJ Jones, Christine Lemke, Ken Ehlert, and Chamath Palihapitiya, who bring extensive experience in biopharmaceuticals and healthcare. This move marks a significant step toward Akili’s goal of scaling digital therapeutics, particularly as it approaches market introduction of its first product.

Vedanta Biosciences, a clinical-stage biopharmaceutical company, has announced participation in two upcoming investor conferences: the William Blair Biotech Focus Conference on July 12-13, 2022, in New York, and the SVB Securities Biopharma Private Company Connect on July 20-21, 2022, offering virtual 1x1 meetings. The company specializes in pioneering oral therapies using defined bacterial consortia, targeting conditions such as C. difficile infection, inflammatory bowel diseases, and cancer. Vedanta boasts over 45 patents and a vast library of bacteria from the human microbiome.

PureTech Health plc has announced the initiation of a clinical study for LYT-100 (deupirfenidone), a potential treatment for idiopathic pulmonary fibrosis (IPF). This global, randomized study aims to assess the efficacy and tolerability of LYT-100 compared to pirfenidone and a placebo. Approximately 240 patients will participate, with topline results expected by the end of 2023. Additionally, the company is advancing its LYT-200 program for solid tumors, with plans to initiate a leukemia study by year-end 2022.

PureTech Health plc has announced the opening of a new large-scale CGMP facility by its Founded Entity, Vedanta Biosciences, to manufacture clinical and commercial supplies for its microbiome therapies. This facility will support the planned Phase 3 clinical trial and potential commercial launch of VE303, targeted at high-risk Clostridioides difficile infection. With established capabilities to produce defined bacterial consortia in compliance with global standards, Vedanta aims to enhance its leadership in microbiome-based therapies.

Vedanta Biosciences announces the opening of a new multi-product CGMP facility in Cambridge, MA, designed to manufacture oral therapies based on defined bacterial consortia. This facility will support the planned Phase 3 clinical trial and potential commercial launch of VE303 for Clostridioides difficile infection. The facility enhances Vedanta's manufacturing capabilities, ensuring compliance with global regulatory standards and addressing critical production challenges for microbiome-based therapies.

On June 15, 2022, PureTech Health held its Annual General Meeting, where shareholders approved all proposed resolutions. Notable outcomes include 100% approval for the Annual Report and Accounts, and the election of several directors. The vote breakdown for director elections showed high support, with the lowest approval at 95.99%. Shareholders also reappointed KPMG as auditors with 97.82% support and authorized the allotment of shares with 97.90% approval. Overall, the meeting reinforced shareholder confidence in the company's leadership and governance.