Welcome to our dedicated page for PureTech Health plc American Depositary Shares news (Ticker: PRTC), a resource for investors and traders seeking the latest updates and insights on PureTech Health plc American Depositary Shares stock.
PureTech Health plc (symbol: PRTC) is a cutting-edge biotechnology company committed to developing and commercializing innovative medicines that address serious diseases. Headquartered in Boston, Massachusetts, PureTech Health specializes in modulating the adaptive human system to create transformative treatments.
The company's core business is focused on discovering and advancing highly differentiated medicines aimed at a wide range of devastating conditions. These include inflammatory, fibrotic, and immunological diseases, as well as intractable cancers, lymphatic and gastrointestinal disorders, and neurological and neuropsychological issues. PureTech Health operates through three key segments: Wholly-Owned Programs, Controlled Founded Entities, and Parent Companies & Others.
Recent Achievements
PureTech Health boasts a robust pipeline of advanced programs that are at the post-human proof of concept stage, targeting some of the most pressing healthcare needs globally. The company's innovative approach has resulted in numerous partnerships and collaborations with leading research institutions and other biopharma entities.
Current Projects
Currently, PureTech Health is involved in several groundbreaking projects aimed at developing treatments that can significantly improve patient outcomes. These projects leverage the company's expertise in modulating the adaptive human system to create therapies that are not only effective but also highly differentiated from existing treatments.
Financial Condition
PureTech Health's financial condition remains strong, supported by a diverse portfolio of wholly-owned programs and controlled founded entities. The company's strategic investments and collaborations have positioned it well to continue driving innovation in the biopharma space.
Partnerships and Collaborations
Collaboration is at the heart of PureTech Health's strategy. The company has established numerous partnerships with top-tier research institutions and other biopharma companies to accelerate the development and commercialization of its innovative therapies.
Products
PureTech Health's product portfolio includes a range of medicines designed to address some of the most challenging diseases. These products are developed with a focus on significantly improving the quality of life for patients.
PureTech Health plc (Nasdaq: PRTC) expresses optimism following its Founded Entity, Karuna, announcing results from a Phase 1b trial of KarXT (xanomeline-trospium) in healthy elderly volunteers. The trial demonstrated that KarXT could be administered at therapeutic doses with a favorable safety and tolerability profile. Karuna plans to launch a Phase 2 trial targeting dementia-related psychosis in the first half of 2022. The majority of participants tolerated doses between 150-200 mg. PureTech holds an 8.2% stake in Karuna and is set to receive royalty payments from future net sales.
PureTech Health (Nasdaq: PRTC) has acquired the remaining 22% of shares in Alivio Therapeutics, enhancing its pipeline targeting inflammatory disorders like inflammatory bowel disease (IBD). This acquisition integrates Alivio’s technology into PureTech’s Wholly Owned Pipeline, including LYT-500, an oral treatment for IBD. This strategic move is set to be funded through partnerships and grants, aligning with PureTech's financial plan extending into Q1 2025. The transaction consists of a cash payment and future milestone payments, which are categorized as smaller transactions under listing rules.
The Annual General Meeting of PureTech Health plc (Nasdaq: PRTC) took place on May 27, 2021, with all proposed resolutions passing successfully. Key results include:
- Approval of the Annual Report for 2020: 100% votes in favor.
- Directors’ Remuneration Report: 89.74% approval.
- Directors’ Remuneration Policy: 83.90% approval.
- Election of directors Dr. Raju Kucherlapati and Dame Marjorie Scardino received 98.73% and 98.54% approval, respectively.
- Reappointment of KPMG LLP as Auditors: 99.90% approval.
These results reflect strong shareholder support for the Company's governance and financial reporting.
PureTech Health plc (Nasdaq: PRTC) noted a significant development from its Founded Entity Gelesis, which presented findings at the AACE 2021 Annual Meeting. A post-hoc analysis indicated that Plenity treatment led to a decline in the NALFD fibrosis score, a marker for liver fibrosis, compared to the placebo group. This analysis supports further trials of Plenity for metabolic-related liver diseases. Gelesis aims to enroll the first patient for a clinical study of its therapeutic candidate in NASH/NAFLD by the year's end.
PureTech Health (Nasdaq: PRTC) announced that Akili Interactive has raised $160 million through a combination of equity and debt financing. The financing includes a $110 million Series D equity round led by Neuberger Berman Funds, with participation from new and existing investors. This round brings Akili’s total equity funding to $230 million. The funds will enhance commercialization efforts for Akili's flagship product, EndeavorRx™, the first prescription video game treatment, and further support the development of digital therapeutics for cognitive disorders.
PureTech Health (Nasdaq: PRTC) announced that Daphne Zohar, Founder and CEO, will participate in a fireside chat at the Jefferies Virtual Healthcare Conference on June 2nd at 9:00 AM EST. The event will be webstreamed for broader access. PureTech is dedicated to developing differentiated medicines for severe diseases and boasts a pipeline of 26 therapeutic candidates. Their expertise focuses on the BIG Axis, integrating brain, immune, and gut biology for innovative treatment options.
PureTech Health (Nasdaq: PRTC) announced the formation of a Clinical Advisory Board to advance LYT-100 (deupirfenidone) for idiopathic pulmonary fibrosis (IPF) and related lung diseases. The board consists of renowned experts in fibrosing lung diseases who will assist in the development of LYT-100, which aims to improve patient compliance due to its favorable safety profile compared to existing treatments. With around 200,000 patients affected by IPF in the U.S., this initiative addresses a significant medical need as current options have tolerability issues.
PureTech Health (Nasdaq: PRTC) announced new preclinical research published in Nature that suggests enhancing meningeal lymphatic drainage could significantly improve clinical outcomes for Alzheimer’s disease. The study links impaired lymphatic function to microglia activation issues, affecting treatment efficacy. This research potentially paves the way for new therapeutic approaches, working alongside existing immunotherapies targeting amyloid beta. PureTech holds an exclusive license for this intellectual property and is advancing this research within its meningeal lymphatics program.
PureTech Health plc (Nasdaq: PRTC) announced that its founded entity, Gelesis, appointed Jane Wildman to its Board of Directors. Wildman brings extensive experience from prominent companies and has a track record of success in brand growth. As Gelesis prepares for the U.S. launch of its weight management product, Plenity®, Wildman's marketing expertise is expected to significantly contribute to the company's strategies. Previously, she led Pampers at Procter & Gamble, doubling its sales from $4 billion to $8 billion. Gelesis focuses on innovative treatments for weight management and related health issues.
Vedanta Biosciences, a pioneering clinical-stage microbiome company, announces CEO Bernat Olle's participation in the 2021 Jefferies Virtual Microbiome-Based Therapeutics Summit on April 22, 2021. He will present on challenges and opportunities in microbiome-based therapeutics. A pre-recording of the presentations will be available at 8:00 AM ET on the same day. Vedanta focuses on developing oral therapies for immune-mediated diseases using defined bacterial consortia, overcoming limitations of donor-derived methods, with a robust clinical pipeline targeting conditions like C. difficile infection and inflammatory bowel diseases.
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