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Prothena Corporation plc (NASDAQ: PRTA) is a leading biotechnology company dedicated to the discovery, development, and commercialization of novel protein immunotherapies. These therapies aim to treat diseases involving amyloid or cell adhesion. Prothena's core business focuses on developing therapeutic monoclonal antibodies that target disease-causing proteins.
The company's investigational therapeutics are designed to address various serious conditions. Prothena's product candidates target a range of indications, including:
- Amyloid Light-chain (AL) amyloidosis (NEOD001): Currently in a global Phase 3 registration clinical trial, known as the VITAL Amyloidosis Study. Additionally, there is an ongoing Phase 1/2 trial.
- Parkinson’s disease and other synucleinopathies (PRX002): Undergoing a Phase 1 multiple ascending dose clinical trial.
- Psoriasis and other inflammatory diseases (PRX003): In a Phase 1 single ascending dose clinical trial.
Prothena’s lead program, NEOD001, is aimed at treating AL amyloidosis, a serious condition that affects the organs. PRX002 and PRX003 are also significant as they target critical unmet needs in neurodegenerative and inflammatory diseases.
The company’s strategy is underpinned by a robust scientific approach and a pipeline of promising candidates. Prothena is led by an elite team with a proven track record in biotechnology and pharmaceuticals, working tirelessly to bring breakthrough therapies to market.
Financially, Prothena is in a strong position, bolstered by strategic partnerships and a focus on high-potential therapeutic areas. The company continues to advance its clinical programs while exploring new avenues for growth and innovation.
Latest News: Stay updated with the most recent developments and updates from Prothena Corporation plc.
Prothena Corporation reported strong financial results for Q3 and the first nine months of 2021, achieving a net income of $109.2 million for Q3 compared to a loss of $30.6 million in Q3 2020. Total revenue reached $139.2 million, including $78.5 million from Bristol Myers Squibb and $60.7 million from Novo Nordisk. The company has $601.5 million in cash and no debt. Prothena continues to advance its pipeline, including the ongoing Phase 3 trial of birtamimab and collaborations with notable partners, positioning itself for further growth.
Prothena Corporation plc (NASDAQ:PRTA) will release its third quarter and first nine months of 2021 financial results on November 4, 2021, after U.S. market close. The company, focused on novel therapies for conditions related to protein dysregulation, will not hold a conference call following the release. Prothena continues to advance its pipeline targeting diseases such as AL amyloidosis, ATTR amyloidosis, Alzheimer's, and Parkinson's. This detailed focus on neurological dysfunction and misfolded proteins positions Prothena as a key player in addressing rare and neurodegenerative diseases.
Prothena Corporation plc (NASDAQ:PRTA) announced the hiring of two new employees, granting them options to purchase a total of 140,000 ordinary shares at an exercise price of $70.74. This price reflects the closing trading price on October 1, 2021. The options will vest over four years, with 25% vesting after one year and the remaining vesting monthly over the following three years. This grant is part of Prothena's 2020 Employment Inducement Incentive Plan, approved by the board under Nasdaq guidelines.
Prothena Corporation (NASDAQ:PRTA) announced key executive changes aimed at bolstering its transition to a fully integrated biotechnology company targeting rare diseases. Tran B. Nguyen has been appointed Chief Strategy Officer while continuing his role as Chief Financial Officer. Brandon Smith steps in as Chief Operating Officer. These roles focus on enhancing Prothena's long-term growth strategy, operational capabilities, and pipeline development, aiding in its mission to commercialize novel therapeutics for conditions like AL amyloidosis and Alzheimer’s disease.
Prothena Corporation plc (NASDAQ:PRTA) announced the approval of a stock option grant to a new employee, allowing the purchase of 75,000 ordinary shares at an exercise price of $69.88. This is based on the closing trading price from September 1, 2021. The option will vest over four years, with 25% vesting after one year and the remainder vesting monthly over the following three years. This grant aligns with Prothena's 2020 Employment Inducement Incentive Plan.
Prothena Corporation plc (NASDAQ:PRTA) announced participation in key investor conferences in September 2021, showcasing its commitment to addressing neurodegenerative diseases. Key events include Citi’s 16th Annual BioPharma Virtual Conference on September 8, featuring a fireside chat at 9:45 AM ET and a panel discussion at 11:35 AM ET. Additionally, the company will present at H.C. Wainwright's 23rd Annual Global Investment Conference on September 13 and the Cantor Global Healthcare Conference on September 27. Webcasts of these events will be available live and subsequently for 90 days on Prothena's website.
Prothena Corporation (NASDAQ:PRTA) reported a net income of $27.6 million for Q2 2021, a significant improvement from a net loss of $26.3 million in the same quarter last year. Revenue for Q2 reached $60.1 million, up from $0.2 million in Q2 2020, primarily driven by collaboration payments. The company announced multiple strategic collaborations, achieving over $200 million in milestone payments in 2021. Prothena anticipates a strong cash position of approximately $491 million by year-end, up from prior guidance of $316 million. Upcoming milestones include key clinical data presentations.
DUBLIN, Ireland, July 29, 2021 – Prothena Corporation plc (NASDAQ:PRTA) will release its second quarter and first half of 2021 financial results on August 5, 2021, after U.S. market close. The company, known for its investigational therapeutics targeting protein dysregulation associated with rare peripheral amyloid and neurodegenerative diseases, will not hold a conference call for this release. Prothena aims to advance its pipeline, which includes treatments for AL amyloidosis, ATTR amyloidosis, Alzheimer's, and Parkinson's diseases.
Prothena Corporation (NASDAQ:PRTA) presented promising data on its Alzheimer’s disease programs at the Alzheimer’s Association International Conference 2021. Highlights include the late-breaking poster on PRX012, demonstrating effective clearance of Aβ plaque in brain tissue, and a dual Aβ-tau vaccine that generates antibodies to target both amyloid and tau pathologies. PRX012 is noted for its high potency and potential for subcutaneous administration, promising improved patient compliance. The Investigational New Drug Application for PRX012 is anticipated in Q1 2022, enhancing Prothena's robust Alzheimer’s portfolio.
Dublin, Ireland, July 20, 2021 - Prothena Corporation plc (NASDAQ:PRTA) announced it will present preclinical data on its Alzheimer’s disease programs at the Alzheimer’s Association International Conference 2021 (July 26-30). The presentations will cover PRX012, a next-generation anti-amyloid beta antibody, and a dual Aβ-tau vaccine. PRX012 aims for improved efficacy and safety, with an IND expected in Q1 2022. The dual vaccine is designed to tackle both Aβ plaques and tau tangles, presenting significant therapeutic potential in addressing Alzheimer's, which currently affects over 5.8 million Americans.
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