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Prothena Corporation plc (NASDAQ: PRTA) is a leading biotechnology company dedicated to the discovery, development, and commercialization of novel protein immunotherapies. These therapies aim to treat diseases involving amyloid or cell adhesion. Prothena's core business focuses on developing therapeutic monoclonal antibodies that target disease-causing proteins.
The company's investigational therapeutics are designed to address various serious conditions. Prothena's product candidates target a range of indications, including:
- Amyloid Light-chain (AL) amyloidosis (NEOD001): Currently in a global Phase 3 registration clinical trial, known as the VITAL Amyloidosis Study. Additionally, there is an ongoing Phase 1/2 trial.
- Parkinson’s disease and other synucleinopathies (PRX002): Undergoing a Phase 1 multiple ascending dose clinical trial.
- Psoriasis and other inflammatory diseases (PRX003): In a Phase 1 single ascending dose clinical trial.
Prothena’s lead program, NEOD001, is aimed at treating AL amyloidosis, a serious condition that affects the organs. PRX002 and PRX003 are also significant as they target critical unmet needs in neurodegenerative and inflammatory diseases.
The company’s strategy is underpinned by a robust scientific approach and a pipeline of promising candidates. Prothena is led by an elite team with a proven track record in biotechnology and pharmaceuticals, working tirelessly to bring breakthrough therapies to market.
Financially, Prothena is in a strong position, bolstered by strategic partnerships and a focus on high-potential therapeutic areas. The company continues to advance its clinical programs while exploring new avenues for growth and innovation.
Latest News: Stay updated with the most recent developments and updates from Prothena Corporation plc.
Prothena Corporation (NASDAQ: PRTA) announced the hiring of two new employees, granting stock options to purchase 50,000 shares at an exercise price of $10.31 each. The options will vest over four years, with 25% vesting after one year and the remainder monthly thereafter. This move is part of Prothena’s 2020 Employment Inducement Incentive Plan aimed at attracting talent in the field of neurodegenerative diseases. Prothena focuses on investigational therapeutics for amyloid diseases and has partnered programs targeting various neurological conditions.
Prothena Corporation plc (NASDAQ: PRTA) will hold an investor webcast today at 1:30 PM ET following Roche's presentation of the Phase 2 PASADENA study results at the MDS Virtual Congress 2020. The webcast will review the findings from this study, which focuses on therapeutics for neurodegenerative diseases. Investors can access the presentation via Prothena's website, with a replay available for 90 days. Prothena specializes in developing treatments for conditions such as Parkinson's disease and amyloidosis, leveraging its expertise in protein dysregulation.
Prothena Corporation (NASDAQ:PRTA) announced encouraging results from the Phase 2 PASADENA study of prasinezumab, an anti-alpha-synuclein antibody aimed at early Parkinson's disease. Although the primary endpoint was not met, significant efficacy signals were observed, including a 35% reduction in motor function decline compared to placebo after one year. The drug also delayed clinically meaningful worsening of motor progression. These results support further clinical development of prasinezumab as a potential disease-modifying therapy, with an investor webcast scheduled for September 15, 2020.
Dublin, Ireland - Prothena Corporation plc (NASDAQ: PRTA) announced that its senior management team will speak at the 2020 Cantor Virtual Global Healthcare Conference on September 15, 2020, at 4:00 PM ET. A webcast of the presentation will be accessible on the company's investor relations website, with a replay available for 90 days post-event. Prothena focuses on developing therapeutics for neurodegenerative and rare peripheral amyloid diseases, with programs targeting conditions like Alzheimer’s, ALS, and Parkinson's disease.
Prothena Corporation (NASDAQ: PRTA) updated the presentation timing for results from Part 1 of the Phase 2 PASADENA study involving prasinezumab for early Parkinson's disease. The oral presentation, originally set for September 14, will now be on September 15 at the 2020 International Congress of Parkinson’s Disease and Movement Disorders Society. Prasinezumab, a humanized monoclonal antibody, targets alpha-synuclein to potentially slow clinical decline in Parkinson's patients. Prothena has partnered with Roche for its development, sharing costs and profits on a 30/70 basis.
Prothena Corporation (NASDAQ:PRTA) reported a net loss of $26.3 million for Q2 2020, significantly higher than $15.8 million in Q2 2019. Total revenue for Q2 remained stable at $0.2 million. The company’s cash position is strong, with $336.6 million available to fund ongoing R&D efforts. Upcoming milestones include presentations of clinical data for their Parkinson’s disease treatment, prasinezumab, and updates on PRX004 for ATTR amyloidosis. Prothena expects full-year cash burn between $75-$85 million, predicting an end-of-year cash position of approximately $299 million.
Prothena Corporation (NASDAQ: PRTA) announced that results from Part 1 of the Phase 2 PASADENA study on prasinezumab for early Parkinson’s disease were selected as an oral Top Abstract at the International Congress of Parkinson’s Disease and Movement Disorders Society (MDS). This session will take place on September 14, 2020, with a poster also displayed in the virtual hall. Prasinezumab aims to block the transmission of aggregated alpha-synuclein, potentially slowing disease progression. Prothena continues its collaboration with Roche, focusing on achieving significant milestones.
Prothena Corporation plc (NASDAQ: PRTA) will announce its Q2 and H1 2020 financial results on August 6, after U.S. market close. The company specializes in neurodegenerative and rare peripheral amyloid diseases, with a pipeline of investigational therapeutics. Notably, Prothena collaborates with Roche on prasinezumab for Parkinson’s disease and partners with Bristol-Myers Squibb on therapies targeting Alzheimer’s and other diseases. Consistent with previous practices, there will be no conference call following the earnings release.
DUBLIN, Ireland, May 27, 2020 (GLOBE NEWSWIRE) -- Prothena Corporation plc (NASDAQ:PRTA) announced its senior management will present at the Jefferies Virtual Healthcare Conference on June 3 at 3:30 PM ET. Investors can access the presentation via the investor relations section of the company's website. A replay will be available for 90 days post-presentation. Prothena focuses on the discovery of therapies for diseases related to protein misfolding, including Alzheimer's and Parkinson's, with a diverse pipeline of partnered and proprietary programs.
Prothena Corporation reported a net loss of $23.6 million for Q1 2020, compared to $20.9 million in Q1 2019, with a net loss per share of $0.59. Total revenue from its collaboration with Roche was only $0.1 million, down from $0.2 million. R&D expenses rose to $15.2 million due to collaboration costs and clinical trials. The cash position remains strong at $355.4 million, but the net cash burn for 2020 is estimated at $75 to $85 million, up from previous guidance. Prothena has ongoing evaluations for its drug programs, including prasinezumab.