PROPANC BIOPHARMA INC - PPCB STOCK NEWS

Propanc Biopharma, Inc. (OTCQB: PPCB) is advancing its lead product candidate, PRP, a novel pharmaceutical formulation combining two proenzymes for I.V. injection in a Phase I First-In-Human study targeting advanced cancer patients. The company has successfully achieved over 95% purity in manufacturing the proenzymes, enhancing the product's stability and shelf life. With over a decade in developmental efforts and compliance with GMP standards, Propanc aims to provide an effective long-term treatment for metastatic cancer, addressing a critical healthcare need.

Propanc Biopharma, Inc. (OTCQB: PPCB) has announced a new cancer treatment approach called differentiation therapy, aiming to induce cancer cells to return to their specific cell types. This method has significant advantages over conventional therapies, as it spares healthy cells from damage. The company is developing a patented pancreatic proenzyme formulation (PRP) to prevent tumor recurrence and metastasis. Initial results suggest PRP effectively reduces cancer cell growth with minimal side effects. Propanc plans to initiate early-stage clinical trials for solid tumors, including pancreatic and ovarian cancers.

Propanc Biopharma, Inc. (OTCQB: PPCB) has announced the procurement of pharmaceutical-grade raw materials for its Phase I First-In-Human study targeting advanced cancer patients with solid tumors. Approximately 0.5kg of trypsinogen and 2.4kg of chymotrypsinogen have been acquired, with a second batch scheduled for mid-year. This marks a significant step in developing its proprietary PRP treatment, which aims to inhibit tumor growth. The initial study will involve 30 to 40 patients, followed by two Phase II studies for pancreatic and ovarian tumors.

Propanc Biopharma, Inc. (OTCQB: PPCB) announced progress on its lead cancer treatment, PRP, a proenzyme therapy aimed at metastatic cancers. PRP is poised for Phase I clinical trials, building on positive results from prior compassionate use studies that showed improved survival rates in advanced cancer patients. Notably, 41.3% of patients in previous studies lived longer than expected. The intravenous administration of PRP is expected to enhance its efficacy, with lower risks of affecting healthy cells compared to conventional treatments. The management remains optimistic about PRP's prospects.

Propanc Biopharma (OTCQB: PPCB) highlights the disruptions in cancer care due to the global pandemic, emphasizing the increased risk of infection for patients. The company aims to advance its lead product candidate, PRP, which targets metastatic cancer without severe side effects or immune suppression. A study indicates that 42% of cancer patients faced treatment disruptions during COVID-19. Propanc is committed to developing effective therapies that enhance patient quality of life amidst these challenges.

Propanc Biopharma (OTC-PINK:PPCB) has received a Notice of Allowance from the USPTO for a patent concerning a novel method to treat cancer stem cells (CSCs) using pancreatic proenzymes. This patent represents a significant advancement in the company's efforts to combat recurrent and metastatic cancer. The method specifically targets and eradicates CSCs, which are often resistant to conventional treatments. The patent is part of a portfolio comprising 65 patents globally. CEO James Nathanielsz highlighted the importance of expanding their intellectual property to enhance long-term shareholder value.

Propanc Biopharma (OTCQB: PPCB) announced its CEO, James Nathanielsz, advocates for proenzyme therapy as a key solution for cancer treatment. This comes alongside President Biden's initiative on lowering prescription drug costs through the 'Build Back Better Bill.' Proenzymes are sourced from bovine sources, offering a cost-effective, less severe alternative to existing cancer therapies. The company is preparing for clinical trials, aiming to reduce the financial burden on patients. Proenzyme therapy aims to target various solid tumors, potentially benefiting a large patient population.

Propanc Biopharma, Inc. (OTCQB: PPCB) has announced advancements in its cancer stem cell technology, PRP, which targets and eradicates cancer stem cells, crucial for combating metastatic cancer. Research indicates PRP regulates key biological pathways associated with cancer spread, potentially offering new hope for patients with solid tumors. CEO James Nathanielsz emphasized plans for a First-In-Human study in advanced cancer patients, following collaborative efforts in Spain and the US. These developments aim to reduce tumor recurrence, thus addressing a significant cause of cancer mortality.

Propanc Biopharma, Inc. (OTCQB: PPCB) announces a 13-year ongoing research partnership with the Universities of Jaén and Granada, Spain. The partnership aims to develop novel cancer treatments, focusing on their lead product candidate, PRP, which is advancing toward First-In-Human clinical studies. The collaboration has resulted in significant advances in drug development, including 5 scientific publications and a portfolio of 65 patents. Propanc's efforts are directed at targeting cancer stem cells to prevent tumor metastasis, with exciting prospects for further discoveries from their ongoing research programs.