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PacBio Announces Third Quarter 2021 Financial Results

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PacBio (NASDAQ: PACB) reported strong financial results for Q3 2021, with revenue reaching $34.9 million, an 83% year-over-year increase. The company installed 44 Sequel II/IIe systems during the quarter, bringing the total installed base to 326 systems. Gross profit soared to $15.4 million, reflecting a 117% increase and a gross margin of 44%. Despite this growth, operating expenses surged to $89.8 million, influenced by substantial stock-based compensation. Net income stood at $16.5 million, a significant turnaround from the $23.7 million loss in Q3 2020.

Positive
  • Revenue of $34.9 million represents an 83% increase YoY.
  • Installed base of 326 Sequel II/IIe systems, up from 168 YoY.
  • Record gross profit of $15.4 million, with a gross margin of 44%.
  • Net income of $16.5 million, a notable improvement from a loss in the prior year.
Negative
  • Operating expenses increased to $89.8 million, a significant rise from $31.2 million YoY.
  • Non-GAAP net loss of $47.2 million, compared to a loss of $23.7 million YoY.

MENLO PARK, Calif., Nov. 02, 2021 (GLOBE NEWSWIRE) -- PacBio (NASDAQ: PACB) today announced financial results for the quarter ended September 30, 2021.

Record revenue reflects 6th straight quarter of sequential growth

  • Revenue of $34.9 million, an 83% increase compared with $19.1 million in the prior year period.
  • Placed 44 Sequel II/IIe systems during the quarter compared to 20 Sequel II systems placed in the prior year quarter and 38 Sequel II/IIe systems placed in the second quarter of 2021.
  • Installed base of 326 Sequel II/IIe systems as of September 30, 2021, compared with 168 as of September 30, 2020.
  • Instrument revenue of $15.9 million, compared with $7.7 million in the prior year period.
  • Consumables revenue of $14.6 million compared with $8.0 million in the prior year period.
  • Service and other revenue of $4.4 million compared with $3.3 million in the prior year period.

Gross profit for the third quarter of 2021 was $15.4 million, representing a 117% increase compared with $7.1 million for the third quarter of 2020 and gross margin of 44% in the period compared to 37% for the third quarter of 2020. Excluding merger-related fair value inventory adjustments and amortization of intangible assets, non-GAAP gross profit for the third quarter of 2021 was $15.7 million and represented a non-GAAP gross margin of 45% in the third quarter of 2021, compared to 37% for the third quarter of 2020.

Operating expenses totaled $89.8 million for the third quarter of 2021, compared to $31.2 million for the third quarter of 2020. Excluding merger-related expenses and amortization of intangible assets, non-GAAP operating expenses totaled $59.1 million for the third quarter of 2021, compared to $31.2 million for the third quarter of 2020. Operating expenses for the third quarter of 2021 and the third quarter of 2020 included non-cash stock-based compensation of $26.6 million and $4.3 million, respectively. Excluding merger-related expenses, operating expenses in the third quarter of 2021 included $15.1 million of non-cash stock-based compensation.

Net income for the third quarter of 2021 was $16.5 million, compared to a net loss of $23.7 million for the third quarter of 2020. Excluding merger-related expenses, an income tax benefit resulting from the acquisitions of Omniome and Circulomics, fair value inventory adjustments, and amortization of intangible assets, non-GAAP net loss for the third quarter of 2021 was $47.2 million, compared to $23.7 million for the third quarter of 2020.

Basic and diluted net income per share for the third quarter of 2021 was $0.08 compared to net loss per share of $0.14 for the third quarter of 2020. Non-GAAP net loss per share for the third quarter of 2021 was $0.23 compared to $0.14 for the third quarter of 2020.

Cash, cash equivalents and investments, excluding short and long-term restricted cash, at September 30, 2021, totaled $1,079.9 million, compared to $318.8 million at December 31, 2020.

Updates since our last earnings release

  • Closed previously announced acquisition of Omniome, which adds a highly differentiated short-read sequencing technology capable of delivering increased sequencing accuracy and establishes a San Diego presence
  • Completed a $300 million PIPE financing in support of Omniome acquisition from a premier syndicate of life sciences investors
  • Partnered with the European Reference Genome Atlas (ERGA) consortium to support its efforts in understanding and protecting biodiversity by generating high-quality reference genomes for European plant and animal species
  • Announced Prenetics Group Limited, a leading global genomics and diagnostic testing company, will use PacBio HiFi sequencing for its comprehensive genetic screening services outside of the United States
  • Sequel II became PacBio’s first regulatory approved instrument as Berry Genomics announced it obtained China NMPA approval for the system and related reagents

“Our focus on execution enabled us to achieve another record quarter, highlighted by Sequel II/IIe installations at an all-time high,” said Christian Henry, President and Chief Executive Officer. “We continue to build momentum, and we are just beginning to see the tangible results from our investments in the business. With approximately 700 global employees, an expanding commercial presence, and groundbreaking short- and long-read products in development, PacBio is in prime position to deliver on its mission to enable the promise of genomics to better human health.”

Impact of COVID-19 Pandemic

Financial results for the third quarter of 2020 were negatively impacted as multiple customers postponed system deliveries, and the financial results for much of 2020 were further impacted as several customers shut down or limited operations for various periods to help curb the spread of the COVID-19 pandemic. Instrument utilization largely returned to normal by the fourth quarter of 2020, and we subsequently have not seen significant issues with deliveries or operations at customer sites. This resulted in higher product revenues of $30.5 million for the third quarter of 2021 compared to $15.7 million for the same period of 2020. Uncertainties associated with the pandemic, including recent resurgences in infection rates, may cause further impacts to our operations and financial results.

Quarterly Conference Call Information

Management will host a quarterly conference call to discuss its third quarter ended September 30, 2021, results today at 4:30 p.m. Eastern Time. Investors may listen to the call by dialing 1.888.366.7247, or if outside the U.S., by dialing +1.707.287.9330, using Conference ID # 5129207. The call will be webcast live and will be available for replay at PacBio’s website at https://investor.pacificbiosciences.com/.

About PacBio

Pacific Biosciences of California, Inc. (NASDAQ: PACB), is empowering life scientists with highly accurate long-read sequencing. The company’s innovative instruments are based on Single Molecule, Real-Time (SMRT®) Sequencing technology, which delivers a comprehensive view of genomes, transcriptomes, and epigenomes, enabling access to the full spectrum of genetic variation in any organism. Cited in thousands of peer-reviewed publications, PacBio® sequencing systems are in use by scientists around the world to drive discovery in human biomedical research, plant and animal sciences, and microbiology.

Statement regarding use of non‐GAAP financial measures

The company reports non‐GAAP results for basic and diluted net income and loss per share, net income, net loss, gross margins, gross profit and operating expenses in addition to, and not as a substitute for, or superior to, financial measures calculated in accordance with GAAP. The company’s financial measures under GAAP include substantial charges such as merger related expenses, and others that are listed in the itemized reconciliations between GAAP and non‐GAAP financial measures included in this press release. The amortization of intangible assets excluded from GAAP financial measures relates to acquired intangible assets that were recorded as part of the purchase accounting this quarter. Such intangible assets contribute to revenue generation and its amortization will recur in future periods until they are fully amortized. Management has excluded the effects of these items in non‐GAAP measures to assist investors in analyzing and assessing past and future operating performance. In addition, management uses non-GAAP measures to compare our performance relative to forecasts and strategic plans and to benchmark our performance externally against competitors.

The company encourages investors to carefully consider its results under GAAP, as well as its supplemental non‐GAAP information and the reconciliation between these presentations, to more fully understand its business. Reconciliations between GAAP and non‐GAAP results are presented in the tables of this release.

Forward-Looking Statements

This press release may contain “forward-looking statements” within the meaning of Section 21E of the Securities Exchange Act of 1934, as amended, and the U.S. Private Securities Litigation Reform Act of 1995, including statements relating to potential increased accuracy of short-read sequencing technology; collaboration efforts, including in connection with establishing reference genomes; potential use of PacBio products and technology by Prenetics Group Limited in its genetic screening products and services; and expectations regarding PacBio’s momentum, potential expansion of commercial presence, capabilities and development of short- and long-read products and technology, position and ability to enable genomics and better human health, and business investments. You should not place undue reliance on forward-looking statements because they involve known and unknown risks, uncertainties, changes in circumstances and other factors that are, in some cases, beyond PacBio’s control and could cause actual results to differ materially from the information expressed or implied by forward-looking statements made in this press release. Factors that could materially affect actual results can be found in PacBio’s most recent filings with the Securities and Exchange Commission, including PacBio’s most recent reports on Forms 8-K, 10-K, and 10-Q, and include those listed under the caption “Risk Factors.” PacBio undertakes no obligation to revise or update information in this press release to reflect events or circumstances in the future, even if new information becomes available.

The condensed consolidated financial statements that follow should be read in conjunction with the notes set forth in PacBio’s Quarterly Report on Form 10-Q when filed with the Securities and Exchange Commission.

Contacts

Investors:
Todd Friedman
650.521.8450
ir@pacificbiosciences.com

Media:
Kathy Lynch
pr@pacificbiosciences.com



Pacific Biosciences of California, Inc.
Unaudited Condensed Consolidated Statement of Operations
(in thousands, except per share amounts)

         
 Three Months Ended
 September 30, 2021 June 30, 2021 September 30, 2020
Revenue:        
Product revenue$30,502  $26,533  $15,749 
Service and other revenue 4,385   4,077   3,333 
Total revenue 34,887   30,610   19,082 
Cost of revenue:        
Cost of product revenue 15,530   13,222   9,228 
Cost of service and other revenue 3,870   3,635   2,790 
Amortization of intangible assets 123       
Total cost of revenue 19,523   16,857   12,018 
Gross profit 15,364   13,753   7,064 
Operating expense:        
Research and development 27,508   22,266   16,467 
Sales, general and administrative 31,606   29,060   14,772 
Merger-related expenses (1) 30,726       
Total operating expense 89,840   51,326   31,239 
         
Operating loss (74,476)  (37,573)  (24,175)
Interest expense (3,673)  (3,589)   
Other income (expense), net (133)  161   467 
Loss before benefit from income taxes (78,282)  (41,001)  (23,708)
Benefit from income taxes (2) (94,824)      
Net income (loss)$16,542  $(41,001) $(23,708)
         
Net income (loss) per share:        
Basic$0.08  $(0.21) $(0.14)
Diluted$0.08  $(0.21) $(0.14)
         
Shares used in computing net income (loss) per share:        
Basic 202,194   198,568   166,862 
Diluted 215,127   198,568   166,862 

__________

(1)   Merger-related expenses for the three months ended September 30, 2021 consist of $11.8 million of transaction costs arising from the acquisitions of Omniome and Circulomics and $18.9 million of stock-based compensation expense resulting from the acceleration of certain equity awards in connection with the Omniome merger.

(2)   A deferred income tax benefit of $94.8 million for the three months ended September 30, 2021, is related to the release of the valuation allowance for deferred tax assets due to the recognition of deferred tax liabilities in connection with the Omniome and Circulomics acquisitions.



Pacific Biosciences of California, Inc.
Unaudited Condensed Consolidated Statement of Operations
(in thousands, except per share amounts)

            
            
 Three Months Ended September 30, Nine Months Ended September 30,
 2021
 2020
 2021
 2020
Revenue:           
Product revenue$30,502  $15,749  $82,338  $41,798 
Service and other revenue 4,385   3,333   12,156   9,959 
Total revenue 34,887   19,082   94,494   51,757 
Cost of revenue:           
Cost of product revenue 15,530   9,228   41,449   22,874 
Cost of service and other revenue 3,870   2,790   10,828   7,718 
Amortization of intangible assets 123      123    
Total cost of revenue 19,523   12,018   52,400   30,592 
Gross profit 15,364   7,064   42,094   21,165 
Operating expense:           
Research and development 27,508   16,467   70,323   46,727 
Sales, general and administrative 31,606   14,772   86,804   54,846 
Merger-related expenses (1) 30,726      30,726    
Total operating expense 89,840   31,239   187,853   101,573 
            
Operating loss (74,476)  (24,175)  (145,759)  (80,408)
Gain (loss) from Continuation Advances from Illumina       (52,000)  34,000 
Interest expense (3,673)     (9,051)  (267)
Other income (expense), net (133)  467   92   1,143 
Loss before benefit from income taxes (78,282)  (23,708)  (206,718)  (45,532)
Benefit from income taxes (2) (94,824)     (94,824)   
Net income (loss)$16,542  $(23,708) $(111,894) $(45,532)
            
Net income (loss) per share:           
Basic$0.08  $(0.14) $(0.56) $(0.29)
Diluted$0.08  $(0.14) $(0.56) $(0.29)
            
Shares used in computing net income (loss) per share:           
Basic 202,194   166,862   198,545   158,195 
Diluted 215,127   166,862   198,545   158,195 

__________

(1)   Merger-related expenses for the three months and nine months ended September 30, 2021 consist of $11.8 million of transaction costs arising from the acquisitions of Omniome and Circulomics and $18.9 million of stock-based compensation expense resulting from the acceleration of certain equity awards in connection with the Omniome merger.

(2)   A deferred income tax benefit of $94.8 million for the three months and nine months ended September 30, 2021, is related to the release of the valuation allowance for deferred tax assets due to the recognition of deferred tax liabilities in connection with the Omniome and Circulomics acquisitions.



Pacific Biosciences of California, Inc.
Unaudited Condensed Consolidated Balance Sheets
(in thousands)

      
 September 30,  December 31,
 2021 2020
Assets   
Cash and investments$1,079,890 $318,814
Accounts receivable 23,946  16,837
Inventory 18,276  14,230
Prepaid and other current assets 7,193  4,870
Property and equipment, net 31,119  24,899
Operating lease right-of-use assets, net 45,862  29,951
Restricted cash 5,060  4,336
Intangible assets, net 411,206  
Goodwill 411,533  
Other long-term assets 70  43
Total Assets$2,034,155 $413,980
      
Liabilities and Stockholders’ Equity     
Accounts payable$4,960 $3,579
Accrued expenses 30,820  17,350
Deferred revenue 28,220  10,290
Operating lease liabilities 57,082  41,999
Contingent consideration liability 168,574  
Convertible senior notes, net 895,915  
Other liabilities 7,777  5,271
Stockholders’ equity 840,807  335,491
Total Liabilities and Stockholders’ Equity$2,034,155 $413,980



Pacific Biosciences of California, Inc.
Reconciliation of Non-GAAP Financial Measures
(in thousands, except per share amounts)

               
 Three Months Ended  Nine Months Ended
 September 30, June 30, September 30, September 30, September 30,
 2021 2021
 2020 2021
 2020
               
GAAP net income (loss)$16,542  $(41,001) $(23,708) $(111,894) $(45,532)
Merger-related expenses (1) 30,726         30,726    
Income tax benefit resulting from acquisitions (2) (94,824)        (94,824)   
Fair value adjustment to Circulomics inventory at acquisition date 183         183    
Amortization of intangible assets 154         154    
Loss (gain) from Continuation Advances from Illumina          52,000   (34,000)
Non-GAAP net loss$(47,219) $(41,001) $(23,708) $(123,655) $(79,532)
               
GAAP net income (loss) per share - diluted$0.08  $(0.21) $(0.14) $(0.56) $(0.29)
Merger-related expenses (1) 0.15         0.15    
Income tax benefit resulting from acquisitions (2) (0.47)        (0.48)   
Loss (gain) from Continuation Advances from Illumina          0.26   (0.21)
Other adjustments and rounding differences 0.01         0.01    
Non-GAAP net loss per share - diluted$(0.23) $(0.21) $(0.14) $(0.62) $(0.50)
               
GAAP gross profit$15,364  $13,753  $7,064  $42,094  $21,165 
Fair value adjustment to Circulomics inventory at acquisition date 183         183    
Amortization of intangible assets 123         123    
Non-GAAP gross profit$15,670  $13,753  $7,064  $42,400  $21,165 
               
GAAP total operating expense$89,840  $51,326  $31,239  $187,853  $101,573 
Merger-related expenses (1) (30,726)        (30,726)   
Amortization of intangible assets (31)        (31)   
Non-GAAP total operating expense$59,083  $51,326  $31,239  $157,096  $101,573 

__________

(1)   Merger-related expenses for the three months and nine months ended September 30, 2021 consist of $11.8 million of transaction costs arising from the acquisitions of Omniome and Circulomics and $18.9 million of stock-based compensation expense resulting from the acceleration of certain equity awards in connection with the Omniome merger.

(2)   A deferred income tax benefit of $94.8 million for the three months and nine months ended September 30, 2021, is related to the release of the valuation allowance for deferred tax assets due to the recognition of deferred tax liabilities in connection with the Omniome and Circulomics acquisitions.


FAQ

What were PacBio's Q3 2021 financial results?

PacBio reported Q3 2021 revenue of $34.9 million, up 83% YoY, with a net income of $16.5 million.

How many Sequel II/IIe systems did PacBio install in Q3 2021?

PacBio installed 44 Sequel II/IIe systems in Q3 2021.

What were the key challenges PacBio faced in Q3 2021?

PacBio reported increased operating expenses of $89.8 million, alongside uncertainties from the ongoing COVID-19 pandemic.

What is PacBio's outlook following their Q3 2021 results?

PacBio remains optimistic, citing growth in instrument installations and a strong installed base as indicators of future performance.

Pacific Biosciences of California, Inc.

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