Ocuphire Announces Late-Breaking Paper for Nyxol for Reversal of Dilation Indication at Annual ASRS Meeting and Five More Presentations at Conferences in July

Rhea-AI Summary

Ocuphire Pharma, Inc. (Nasdaq: OCUP), a clinical-stage ophthalmic biopharmaceutical company, announced significant presentations at multiple industry events in July 2022. CEO Mina Sooch will present at the 11th Annual AECOS Summer Symposium, sharing insights on Nyxol and other treatments. A late-breaking paper on Nyxol’s Phase 3 trials will be presented at the ASRS meeting, alongside interim safety data for APX3330 in diabetic retinopathy. Ocuphire aims to advance innovations in ophthalmic therapies and continue engaging with leading medical professionals.

Positive

• Significant presentations at industry conferences can enhance visibility and credibility.
• Positive data from Phase 3 trials for Nyxol may bolster investor confidence and potential market uptake.
• Plans for further clinical trials and presentations indicate continued innovation and development in ophthalmic therapies.

Negative

• None.

Mina Sooch CEO to Present at Ophthalmic Innovation Panel at the 11^th Annual AECOS Summer Symposium and OIS Retina Innovation Summit

ASRS Late-Breaking Paper Highlighting Data from Two Phase 3 Registration Trials in Reversal of Mydriasis for Nyxol

Second ASRS Presentation Features New Interim Masked Safety Data from APX3330 Phase 2b Trial in Diabetic Retinopathy

Ocuphire to Present at OCTANE and at the National Medical Association (NMA)’s Annual Convention and Scientific Assembly

FARMINGTON HILLS, Mich., July 07, 2022 (GLOBE NEWSWIRE) -- Ocuphire Pharma, Inc. (Nasdaq: OCUP), a clinical-stage ophthalmic biopharmaceutical company focused on developing and commercializing therapies for the treatment of refractive and retinal eye disorders, today announced six presentations in July at American-European Congress of Ophthalmic Surgery (AECOS), American Society of Retina Specialists (ASRS), Ophthalmology Innovation Summit (OIS), Octane and National Medical Association (NMA).

At ASRS 2022 in New York, key thought leader David Boyer, MD will present for the first time to the retina medical community a late-breaking paper highlighting data from two Phase 3 registration trials in the reversal of mydriasis/dilation for Nyxol. In addition to the late-breaking presentation, Michael Allingham, MD, Ph.D. will present new interim masked safety data for APX3330 from ZETA-1 Phase 2b trial in diabetic retinopathy.

11th Annual AECOS Summer Symposium
Panel:	Ophthalmic Innovation Forum
Date:	Saturday, July 9, 2022, 8:10 AM – 10:00 AM MDT
Presenter:	Mina Sooch, MBA, CEO
Location:	St Regis Hotel, Deer Valley, Utah
Link:	11th Annual AECOS Summer Symposium
Ophthalmology Innovation Summit OIS Retina 2022
Session:	Innovation Showcase
Date:	Wednesday, July 13, 2022, 8:50 AM – 10:15 AM EDT
Presenter:	Mina Sooch, MBA, CEO and Founder, Ocuphire
Location:	Javits Center, New York
Link:	OIS Retina 2022
ASRS 40th Annual Scientific Meeting
Title:	Masked Safety Data from ZETA-1, an Ongoing 24-Week Phase 2 Clinical Trial of APX3330, an Oral Therapeutic for the Treatment of Diabetic Retinopathy
Date:	Thursday, July 14, 2022, 10:42 AM EDT
Presenter:	Michael Allingham, MD, PhD, Assistant Professor of Ophthalmology, Vitreoretinal Disease, Duke Eye Center
Location:	Javits Center, New York
Link:	ASRS 40th Annual Scientific Meeting
Title:	Late-Breaking Paper Phentolamine Ophthalmic Solution Rapidly Reverses Pharmacologically Induced Mydriasis in Two Pivotal Phase 3 MIRA Trials
Date:	Saturday, July 16, 2022, 3:35 PM EDT
Presenter:	David Boyer, MD, Senior Partner, Retina-Vitreous Associates Medical Group
Location:	Javits Center, New York
Link:	ASRS 40th Annual Scientific Meeting
Women Leaders of Octane – July Quarterly Meeting
Title:	Spotlight Thought Leader
Date:	Wednesday, July 20, 12:00 – 1:00 PM PDT
Presenter:	Mina Sooch, MBA, CEO and Founder, Ocuphire
Format:	Virtual
Link:	Women Leaders of Octane – July 2022 Quarterly Meeting
National Medical Association (NMA) – Annual Convention & Scientific Assembly
Panel:	Physician and Industry Collaborations to Foster Innovation
Date:	Saturday, July 30, 10:00 AM EDT
Presenter:	Bindu Manne, Head of Market Development and Commercialization, Ocuphire
Location:	Atlanta, Georgia
Link:	NMA Annual Convention and Scientific Assembly

About Ocuphire Pharma

Ocuphire is a publicly-traded (NASDAQ: OCUP), clinical-stage ophthalmic biopharmaceutical company focused on developing and commercializing small-molecule therapies for the treatment of refractive and retinal eye disorders. The Company’s lead product candidate, Nyxol^® eye drops (0.75% phentolamine ophthalmic solution), is a once-daily, preservative-free eye drop formulation of phentolamine mesylate, a non-selective alpha-1 and alpha-2 adrenergic antagonist designed to reduce pupil size, and is being developed for several indications, including reversal of pharmacologically-induced mydriasis (RM), presbyopia and dim light or night vision disturbances (NVD), and has been studied in 12 completed clinical trials. Ocuphire has reported positive data from MIRA-2 and MIRA-3 registration trials and MIRA-4 pediatric safety trial for the treatment of RM. Ocuphire also reported positive topline data from the VEGA-1 Phase 2 trial of Nyxol for treatment of presbyopia, both Nyxol as a single agent and Nyxol with low dose pilocarpine (“LDP”) 0.4% as adjunctive therapy. The Company recently reported positive topline results from LYNX-1 Phase 3 trial of Nyxol for NVD. Ocuphire’s second product candidate, APX3330, is an oral tablet designed to inhibit angiogenesis and inflammation pathways relevant to retinal and choroidal vascular diseases, such as diabetic retinopathy (DR) and diabetic macular edema (DME) and has been studied in 11 Phase 1 and 2 trials. The Company announced in March the completion of enrollment in the ZETA-1 Phase 2b clinical trial of APX3330 to treat DR/DME. Please visit www.clinicaltrials.gov to learn more about Ocuphire’s ongoing APX3330 Phase 2b trial in DR/DME ZETA-1 (NCT04692688) and completed Nyxol trials: Phase 3 registration trial in NVD LYNX-1 (NCT04638660), Phase 3 registration trials in RM MIRA-2 (NCT04620213) and MIRA-3 (NCT05134974), MIRA-4 Phase 3 pediatric safety study (NCT05223478), and Phase 2 trial in presbyopia VEGA-1 (NCT04675151). As part of its strategy, Ocuphire will continue to explore opportunities to acquire additional ophthalmic assets and seek strategic partners for late-stage development, regulatory preparation, and commercialization of drugs in key global markets. For more information, visit www.ocuphire.com. 

Contacts

Corporate

Mina Sooch, President & CEO
Ocuphire Pharma, Inc.
ir@ocuphire.com
www.ocuphire.com

Investors

Corey Davis, Ph.D.
LifeSci Advisors
cdavis@lifesciadvisors.com

 

FAQ

What presentations is Ocuphire Pharma participating in July 2022?

Ocuphire Pharma is presenting at the AECOS Summer Symposium, ASRS Annual Scientific Meeting, and several other events in July 2022.

What is the focus of Ocuphire's research and development?

Ocuphire focuses on developing therapies for refractive and retinal eye disorders, including Nyxol for mydriasis reversal and APX3330 for diabetic retinopathy.

Who is presenting at the ASRS meeting for Ocuphire?

David Boyer, MD, will present a late-breaking paper on Nyxol’s Phase 3 trials at the ASRS meeting.

What is Nyxol used for?

Nyxol is developed for reversing pharmacologically-induced mydriasis, treating presbyopia, and addressing night vision disturbances.

What is the significance of the Phase 2b trial for APX3330?

The Phase 2b trial for APX3330 is crucial for assessing its safety and efficacy in treating diabetic retinopathy.