NAVIDEA BIOPHARMS INC - NAVB STOCK NEWS

Navidea Biopharmaceuticals, Inc. (NYSE American: NAVB) has settled ongoing litigation with Platinum-Montaur Life Sciences LLC, resolving claims for approximately $1.9 million. This settlement ends the litigation while allowing Navidea to continue trading on NYSE American, despite receiving a compliance letter on January 28, 2022, regarding listing standards violations. Navidea must submit a compliance plan by February 27, 2022, to avoid delisting risks by July 28, 2023. The company's stock will trade under the designation '.BC' due to this non-compliance status.

Navidea Biopharmaceuticals, Inc. (NYSE American: NAVB) has launched the NAV3-33 Phase 3 clinical trial to evaluate the efficacy of Tc99m tilmanocept imaging in predicting treatment response in patients with moderate to severe rheumatoid arthritis (RA) switching to anti-TNFα therapy. This trial aims to reduce the lengthy trial-and-error process of treatment selection, providing an early, objective assessment of treatment efficacy by measuring macrophage density changes in joints. Results from a previous Phase 2b trial support the hypothesis that this imaging can facilitate timely adjustments in patient treatment.

Navidea Biopharmaceuticals, Inc. (NYSE American: NAVB) has completed full enrollment in the NAV3-35 Phase 2b clinical study focused on establishing a normative database for rheumatoid arthritis (RA) imaging with Tc99m tilmanocept. The study will help in quantifying RA-related inflammation by comparing healthy subjects' joint images to those of RA patients. The trial includes 120 healthy volunteers in Arm 1 and aims to enhance the accuracy of RA treatment predictions. This crucial step supports the development of advanced imaging tools and prepares for an upcoming Phase 3 trial.

Navidea Biopharmaceuticals (NYSE American: NAVB) has terminated its Stock Purchase Agreement initially executed on August 30, 2020. The agreement allowed investors to purchase up to $25.0 million in shares at $5.00 per share. However, only $25,000 was received from the deal, with the company notifying investors of the termination on December 14, 2021. The company continues to focus on precision immunodiagnostic agents and immunotherapeutics, with ongoing developments in its Manocept platform.

Navidea Biopharmaceuticals, Inc. (NYSE American: NAVB) has announced a third-party asset valuation of its Rheumatoid Arthritis diagnostic product candidate, Tc99m tilmanocept. Conducted by LifeSci Partners, the valuation suggests potential peak U.S. sales of $1 billion annually, with an upside scenario reaching $1.8 billion. The product aims to evaluate treatment efficacy of anti-TNFα therapy in RA. A Phase 3 trial is planned to assess its ability as an early treatment response predictor. The company emphasizes its commitment to addressing unmet medical needs in RA patients.

Navidea Biopharmaceuticals (NYSE American: NAVB) announced a conference call for December 16, 2021, following the resignation of Thomas Farb and Agnieszka Winkler from its Board of Directors, effective December 5, 2021. The call, hosted by key executives including Chairman Alexander L. Cappello, will address recent developments and strategic updates. The company aims to enhance patient care through its Manocept platform, focusing on precision immunodiagnostic agents and immunotherapeutics.

Navidea Biopharmaceuticals (NAVB) announced its Q3 2021 financial results, reporting total net revenues of $96,000, down from $268,000 in Q3 2020. For the first nine months, revenues were $481,000, compared to $695,000 in the same period last year. The net loss for Q3 was $2.4 million, or $0.08 per share, a decrease from $3.3 million, or $0.13 per share, in Q3 2020. The company is advancing its clinical programs in Rheumatoid Arthritis and ended Q3 with $7.2 million in cash. A conference call is scheduled for November 10, 2021 at 5:00 PM EST to provide further updates.

Navidea Biopharmaceuticals (NYSE American: NAVB) is preparing a conference call on November 10, 2021 at 5:00 p.m. EST to discuss third-quarter financial results and corporate developments. Dr. Michael Rosol and Erika Eves will present updates and engage with submitted questions. The call will not accommodate live inquiries but allows pre-submitted questions. Navidea focuses on developing precision immunodiagnostic agents and immunotherapeutics, leveraging its Manocept platform for enhanced diagnostic accuracy and treatment.

Navidea Biopharmaceuticals has announced the resignation of Jed A. Latkin as CEO, CFO, COO, and Board member, effective October 24, 2021. The company is currently forming an Office of the CEO with three Board members, including the Chairman, to lead operations during the interim period while seeking a new CEO with an executive search firm.

This leadership change may impact the direction and strategy of the company, which is focused on developing precision immunodiagnostic agents. Details of Latkin's severance agreement are under discussion.