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Merus N.V. Common Shares - MRUS STOCK NEWS

Welcome to our dedicated page for Merus N.V. Common Shares news (Ticker: MRUS), a resource for investors and traders seeking the latest updates and insights on Merus N.V. Common Shares stock.

Merus N.V. (Nasdaq: MRUS) is a clinical-stage immuno-oncology company focused on creating innovative therapies to treat and potentially cure cancer. At the heart of Merus' approach is its proprietary Biclonics® and Triclonics® technology platforms, which generate full-length human bispecific and trispecific antibodies. These advanced therapeutics are designed to engage the immune system to kill tumor cells and inhibit tumor cell growth pathways simultaneously.

Core Business

Merus' core business revolves around the discovery and development of bispecific antibody therapeutics. Their flagship technology, Biclonics®, can attack tumors in multiple ways, making them highly effective against various cancer types. The company’s portfolio includes several promising candidates, such as MCLA-128, which targets HER2 and HER3 receptors in gastric and breast cancers; MCLA-117, targeting AML; MCLA-158 (petosemtamab), focused on head and neck squamous cell carcinoma; and MCLA-145, developed for solid tumors.

Latest Achievements and News

As of May 2024, Merus has received the FDA's Breakthrough Therapy Designation (BTD) for petosemtamab in treating patients with recurrent or metastatic head and neck squamous cell carcinoma (HNSCC) that has progressed after treatment with platinum-based chemotherapy and PD-1/PD-L1 antibodies. This significant milestone is based on the promising data from the ongoing phase 1/2 trial of petosemtamab as a monotherapy, showing substantial improvement in clinically significant endpoints. Furthermore, Merus has announced plans to initiate a phase 3 trial in mid-2024 to evaluate the combination of petosemtamab and pembrolizumab in previously untreated patients.

Additionally, Merus revealed the acceptance of abstracts for MCLA-145 and MCLA-129 at the 2024 American Society of Clinical Oncology (ASCO) Annual Meeting. These presentations highlighted the clinical activity of MCLA-145 in advanced solid tumors and the efficacy of MCLA-129 in non-small cell lung cancer (NSCLC).

Financial Condition and Partnerships

Merus has a solid financial foundation, bolstered by strategic partnerships and collaborations. Notably, Merus collaborates with Betta Pharmaceuticals to develop MCLA-129 in China while retaining global rights outside China. The company’s financial strategy includes advancing its clinical development programs and supporting preclinical research and technology development through successful capital raises.

About Merus N.V.

Merus N.V. is dedicated to the development of multispecific antibody therapeutics, referred to as Multiclonics®. These therapeutics have been observed in preclinical and clinical studies to exhibit the same features as conventional human monoclonal antibodies, including long half-life and low immunogenicity. For more information, visit Merus’ official website, Twitter, and LinkedIn.

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Merus N.V. announces the acceptance of abstracts on bispecific antibodies MCLA-129 and zenocutuzumab for presentation at the ESMO Asia Congress 2023.
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Merus N.V. CEO to participate in investor conferences
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Merus N.V. announces the pricing of an underwritten public offering of 6,818,182 common shares at $22.00 per share, with an option for the underwriters to purchase an additional 1,022,727 common shares. The gross proceeds from the offering are expected to be approximately $150.0 million.
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Merus N.V. (Nasdaq: MRUS) has announced the launch of a proposed underwritten public offering of its common shares to advance the clinical development of its product candidates and for general corporate purposes.
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Merus N.V. announces financial results for Q2 and provides business update. Petosemtamab granted Fast Track Designation for head & neck cancer. Breakthrough Therapy Designations granted for Zeno in lung and pancreatic cancer. Merus plans to initiate phase 3 trial of petosemtamab in mid-2024. Enrollment continues for Zeno and MCLA-129 trials. Merus working with Incyte Corporation on bispecific antibody programs.
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Merus N.V., a clinical-stage oncology company, announced that two abstracts featuring updated interim clinical data for its targeted bispecific antibody, zenocutuzumab (Zeno), have been selected for presentation at the European Society for Medical Oncology Congress (ESMO) 2023. The abstracts will focus on NRG1+ non-small cell lung cancer (NSCLC) and pancreatic ductal adenocarcinoma (PDAC). Merus is currently enrolling patients for the phase 1/2 eNRGy trial to assess the safety and anti-tumor activity of Zeno monotherapy in NRG1+ cancer.
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Merus N.V. has received Breakthrough Therapy Designation (BTD) from the FDA for zenocutuzumab (Zeno) for the treatment of NRG1+ non-small cell lung cancer. This follows previous designations for pancreatic cancer and metastatic solid tumors harboring NRG1 gene fusions. Merus plans to engage in discussions with the FDA for expedited development and review, and will provide updates on the potential Biologics License Application (BLA) submission.
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FAQ

What is the current stock price of Merus N.V. Common Shares (MRUS)?

The current stock price of Merus N.V. Common Shares (MRUS) is $41.85 as of December 20, 2024.

What is the market cap of Merus N.V. Common Shares (MRUS)?

The market cap of Merus N.V. Common Shares (MRUS) is approximately 2.9B.

What is the core business of Merus N.V.?

Merus N.V. focuses on creating innovative therapies to treat and potentially cure cancer using its proprietary Biclonics® and Triclonics® platforms, which generate full-length human bispecific and trispecific antibodies.

What are some of Merus' key product candidates?

Key product candidates include MCLA-128 for gastric and breast cancers, MCLA-117 for AML, MCLA-158 (petosemtamab) for head and neck squamous cell carcinoma, and MCLA-145 for solid tumors.

What significant recent achievement has Merus reported?

Merus received the FDA’s Breakthrough Therapy Designation (BTD) for petosemtamab in treating recurrent or metastatic head and neck squamous cell carcinoma (HNSCC) that progressed after platinum-based chemotherapy and PD-1/PD-L1 antibodies.

What are Biclonics®?

Biclonics® are bispecific antibodies that can attack tumors in multiple ways, such as activating the immune system and directly inhibiting tumor cell growth pathways.

What is the status of MCLA-145 and MCLA-129?

Both MCLA-145 and MCLA-129 have shown promising clinical activity and were presented at the 2024 American Society of Clinical Oncology (ASCO) Annual Meeting, with MCLA-145 addressing solid tumors and MCLA-129 targeting non-small cell lung cancer (NSCLC).

What are Multiclonics®?

Multiclonics® are full-length human bispecific and trispecific antibody therapeutics developed by Merus, exhibiting long half-life and low immunogenicity similar to conventional human monoclonal antibodies.

Who are Merus' key partners?

One of Merus' notable partners is Betta Pharmaceuticals, which collaborates on developing MCLA-129 in China, while Merus retains global rights outside China.

What are the financial strategies of Merus?

Merus' financial strategies include advancing clinical development programs, supporting preclinical research, and raising capital through offerings, backed by strong partnerships and collaborations.

What is the purpose of the latest capital raise by Merus?

The latest capital raise aims to advance the clinical development of Merus' product candidates, support preclinical research and technology development, and for general corporate purposes.

Where can I find more information about Merus N.V.?

For more information, visit Merus’ official website, Twitter, and LinkedIn pages.

Merus N.V. Common Shares

Nasdaq:MRUS

MRUS Rankings

MRUS Stock Data

2.89B
66.39M
2.03%
105.65%
12.79%
Biotechnology
Pharmaceutical Preparations
Link
United States of America
3584 CM UTRECHT