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Merus N.V. Common Shares - MRUS STOCK NEWS

Welcome to our dedicated page for Merus N.V. Common Shares news (Ticker: MRUS), a resource for investors and traders seeking the latest updates and insights on Merus N.V. Common Shares stock.

Merus N.V. (Nasdaq: MRUS) is a clinical-stage immuno-oncology company focused on creating innovative therapies to treat and potentially cure cancer. At the heart of Merus' approach is its proprietary Biclonics® and Triclonics® technology platforms, which generate full-length human bispecific and trispecific antibodies. These advanced therapeutics are designed to engage the immune system to kill tumor cells and inhibit tumor cell growth pathways simultaneously.

Core Business

Merus' core business revolves around the discovery and development of bispecific antibody therapeutics. Their flagship technology, Biclonics®, can attack tumors in multiple ways, making them highly effective against various cancer types. The company’s portfolio includes several promising candidates, such as MCLA-128, which targets HER2 and HER3 receptors in gastric and breast cancers; MCLA-117, targeting AML; MCLA-158 (petosemtamab), focused on head and neck squamous cell carcinoma; and MCLA-145, developed for solid tumors.

Latest Achievements and News

As of May 2024, Merus has received the FDA's Breakthrough Therapy Designation (BTD) for petosemtamab in treating patients with recurrent or metastatic head and neck squamous cell carcinoma (HNSCC) that has progressed after treatment with platinum-based chemotherapy and PD-1/PD-L1 antibodies. This significant milestone is based on the promising data from the ongoing phase 1/2 trial of petosemtamab as a monotherapy, showing substantial improvement in clinically significant endpoints. Furthermore, Merus has announced plans to initiate a phase 3 trial in mid-2024 to evaluate the combination of petosemtamab and pembrolizumab in previously untreated patients.

Additionally, Merus revealed the acceptance of abstracts for MCLA-145 and MCLA-129 at the 2024 American Society of Clinical Oncology (ASCO) Annual Meeting. These presentations highlighted the clinical activity of MCLA-145 in advanced solid tumors and the efficacy of MCLA-129 in non-small cell lung cancer (NSCLC).

Financial Condition and Partnerships

Merus has a solid financial foundation, bolstered by strategic partnerships and collaborations. Notably, Merus collaborates with Betta Pharmaceuticals to develop MCLA-129 in China while retaining global rights outside China. The company’s financial strategy includes advancing its clinical development programs and supporting preclinical research and technology development through successful capital raises.

About Merus N.V.

Merus N.V. is dedicated to the development of multispecific antibody therapeutics, referred to as Multiclonics®. These therapeutics have been observed in preclinical and clinical studies to exhibit the same features as conventional human monoclonal antibodies, including long half-life and low immunogenicity. For more information, visit Merus’ official website, Twitter, and LinkedIn.

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Gilead Sciences and Merus N.V. collaborate to develop novel trispecific antibodies targeting dual tumor-associated antigens. Merus to lead early-stage research with Gilead having the option to license resulting programs. The agreement includes upfront payments, equity investment, and potential milestone payments totaling up to $1.5 billion.
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Merus N.V. (MRUS) announces the preclinical evaluation of bispecific antibody zenocutuzumab (Zeno) for cancer treatment at AACR 2024. Zeno shows promising anti-tumor efficacy in high NRG1-expressing cancer models, indicating potential for Biologics License Application submissions in lung and pancreatic cancer.
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Merus N.V. (MRUS) CEO to participate in fireside chat at Leerink Partners Global Biopharma Conference. The company is a clinical-stage oncology firm focusing on innovative multispecific antibodies.
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Merus N.V. announces plans for transformative year in 2024 with phase 3 trials, BLA submissions, and ongoing clinical developments. Financial results show increased collaboration revenue, extended cash runway, and progress in key partnerships.
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Merus N.V. (MRUS) announced that its CEO will participate in investor conferences on February 7th and 22nd, 2024. The webcasts will be available on the company's website.
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Merus N.V. (Nasdaq: MRUS) announced updated interim clinical data on MCLA-129 from ongoing expansion cohorts in non-small cell lung cancer (NSCLC) and in previously treated head and neck squamous cell carcinoma (HNSCC) at the European Society for Medical Oncology (ESMO) Asia Congress 2023.
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Merus N.V. (MRUS) announces the publication of two abstracts regarding MCLA-129 on the European Society for Medical Oncology (ESMO) Asia Congress website. The abstracts highlight updated interim clinical data from expansion cohorts in non-small cell lung cancer (NSCLC) and in previously treated head and neck squamous cell carcinoma (HNSCC) for presentation at the ESMO Asia Congress 2023 taking place in Singapore December 1-3, 2023.
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Merus N.V. announced financial results for Q3 2023 and provided a business update. The company plans to submit potential BLA applications for its Zeno and petosemtamab programs. Clinical data for Zeno in NRG1+ NSCLC and PDAC show robust efficacy. The company also raised $172M in a public offering, with existing funds expected to support operations into 2027.
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Merus N.V. announced that its CEO, Bill Lundberg, will participate in two investor conferences: BMO Biopharma Spotlight Series: Oncology Day on November 8 and Stifel 2023 Healthcare Conference on November 14. The BMO conference will have a fireside chat with no live webcast, while the Stifel conference will have a live webcast. Archived presentations will be available on the company's website for a limited time.
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Merus N.V. announces interim clinical data for zenocutuzumab in NRG1+ cancer patients, showing promising results and potential for BLA submissions
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FAQ

What is the current stock price of Merus N.V. Common Shares (MRUS)?

The current stock price of Merus N.V. Common Shares (MRUS) is $41.85 as of December 20, 2024.

What is the market cap of Merus N.V. Common Shares (MRUS)?

The market cap of Merus N.V. Common Shares (MRUS) is approximately 2.9B.

What is the core business of Merus N.V.?

Merus N.V. focuses on creating innovative therapies to treat and potentially cure cancer using its proprietary Biclonics® and Triclonics® platforms, which generate full-length human bispecific and trispecific antibodies.

What are some of Merus' key product candidates?

Key product candidates include MCLA-128 for gastric and breast cancers, MCLA-117 for AML, MCLA-158 (petosemtamab) for head and neck squamous cell carcinoma, and MCLA-145 for solid tumors.

What significant recent achievement has Merus reported?

Merus received the FDA’s Breakthrough Therapy Designation (BTD) for petosemtamab in treating recurrent or metastatic head and neck squamous cell carcinoma (HNSCC) that progressed after platinum-based chemotherapy and PD-1/PD-L1 antibodies.

What are Biclonics®?

Biclonics® are bispecific antibodies that can attack tumors in multiple ways, such as activating the immune system and directly inhibiting tumor cell growth pathways.

What is the status of MCLA-145 and MCLA-129?

Both MCLA-145 and MCLA-129 have shown promising clinical activity and were presented at the 2024 American Society of Clinical Oncology (ASCO) Annual Meeting, with MCLA-145 addressing solid tumors and MCLA-129 targeting non-small cell lung cancer (NSCLC).

What are Multiclonics®?

Multiclonics® are full-length human bispecific and trispecific antibody therapeutics developed by Merus, exhibiting long half-life and low immunogenicity similar to conventional human monoclonal antibodies.

Who are Merus' key partners?

One of Merus' notable partners is Betta Pharmaceuticals, which collaborates on developing MCLA-129 in China, while Merus retains global rights outside China.

What are the financial strategies of Merus?

Merus' financial strategies include advancing clinical development programs, supporting preclinical research, and raising capital through offerings, backed by strong partnerships and collaborations.

What is the purpose of the latest capital raise by Merus?

The latest capital raise aims to advance the clinical development of Merus' product candidates, support preclinical research and technology development, and for general corporate purposes.

Where can I find more information about Merus N.V.?

For more information, visit Merus’ official website, Twitter, and LinkedIn pages.

Merus N.V. Common Shares

Nasdaq:MRUS

MRUS Rankings

MRUS Stock Data

2.89B
66.39M
2.03%
105.65%
12.79%
Biotechnology
Pharmaceutical Preparations
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United States of America
3584 CM UTRECHT