Medicus Pharma Ltd. Appoints Faisal Mehmud, MD, MRCP as Chief Medical Officer
Medicus Pharma announces key leadership changes with the appointment of Faisal Mehmud, MD as Chief Medical Officer and the promotion of Edward Brennan, MD to Chief Scientific Officer & Head of R&D. Dr. Mehmud brings over 20 years of global pharmaceutical experience from companies like GSK, Pfizer, and BMS. The company is developing a novel dissolvable doxorubicin-containing microneedle array (D-MNA) to treat non-melanoma skin cancer. Their Phase 1 study completed in March 2021 showed safety and tolerability, with six participants achieving complete response. A Phase 2 clinical trial is currently recruiting 60 patients across nine U.S. sites to evaluate two dose levels against placebo.
Medicus Pharma annuncia importanti cambiamenti nel leadership con l'appuntamento di Faisal Mehmud, MD come Chief Medical Officer e la promozione di Edward Brennan, MD a Chief Scientific Officer e Capo della Ricerca e Sviluppo. Il Dr. Mehmud porta con sé oltre 20 anni di esperienza globale nel settore farmaceutico, lavorando per aziende come GSK, Pfizer e BMS. L'azienda sta sviluppando un innovativo array di microneedle contenente doxorubicina solubile (D-MNA) per il trattamento del cancro della pelle non melanoma. Il loro studio di Fase 1 completato a marzo 2021 ha mostrato sicurezza e tollerabilità, con sei partecipanti che hanno ottenuto una risposta completa. Attualmente, un trial clinico di Fase 2 sta reclutando 60 pazienti in nove siti negli Stati Uniti per valutare due livelli di dose rispetto al placebo.
Medicus Pharma anuncia cambios clave en su liderazgo con el nombramiento de Faisal Mehmud, MD como Director Médico y la promoción de Edward Brennan, MD a Director Científico y Jefe de I+D. El Dr. Mehmud aporta más de 20 años de experiencia farmacéutica global en compañías como GSK, Pfizer y BMS. La empresa está desarrollando una matriz de microagujas disolventes que contiene doxorrubicina (D-MNA) para tratar el cáncer de piel no melanoma. Su estudio de Fase 1, completado en marzo de 2021, mostró seguridad y tolerabilidad, con seis participantes que lograron una respuesta completa. Actualmente, se está reclutando un ensayo clínico de Fase 2 con 60 pacientes en nueve sitios de EE. UU. para evaluar dos niveles de dosis frente a un placebo.
메디커스 제약은 파이살 메흐무드 박사를 최고 의료 책임자로 임명하고 에드워드 브레난 박사를 최고 과학 책임자 겸 연구개발 부서장으로 승진시키는 주요 리더십 변화를 발표했습니다. 메흐무드 박사는 GSK, 화이자, BMS와 같은 회사에서 20년 이상의 글로벌 제약 경험을 가지고 있습니다. 이 회사는 비흑색종 피부암 치료를 위한 혁신적인 용해 가능한 독소루비신 포함 마이크로니들 배열 (D-MNA)를 개발하고 있습니다. 그들의 1상 연구는 2021년 3월에 완료되었으며 안전성과 내약성을 보여주었고, 6명의 참가자가 완전 반응을 보였습니다. 현재 2상 임상 시험이 미국 9개 장소에서 60명의 환자를 모집하여 두 가지 용량 수준을 위약과 비교 평가하고 있습니다.
Medicus Pharma annonce des changements clés dans son équipe de direction avec la nomination de Faisal Mehmud, MD en tant que directeur médical et la promotion de Edward Brennan, MD au poste de directeur scientifique et responsable de la R&D. Le Dr Mehmud apporte plus de 20 ans d'expérience dans l'industrie pharmaceutique mondiale au sein d'entreprises telles que GSK, Pfizer et BMS. L'entreprise développe un réseau de micro-aiguilles contenant de la doxorubicine soluble (D-MNA) pour traiter le cancer de la peau non mélanome. Leur étude de phase 1, achevée en mars 2021, a montré la sécurité et la tolérabilité, avec six participants atteignant une réponse complète. Un essai clinique de phase 2 recrute actuellement 60 patients sur neuf sites aux États-Unis pour évaluer deux niveaux de dose par rapport à un placebo.
Medicus Pharma kündigt wichtige Führungswechsel an, darunter die Ernennung von Faisal Mehmud, MD zum Chief Medical Officer und die Beförderung von Edward Brennan, MD zum Chief Scientific Officer und Leiter der Forschung und Entwicklung. Dr. Mehmud bringt über 20 Jahre globale Erfahrung in der Pharmaindustrie aus Unternehmen wie GSK, Pfizer und BMS mit. Das Unternehmen entwickelt eine neuartige lösliche Doxorubicin-haltige Mikronadelmatrix (D-MNA), um nicht-melanozytären Hautkrebs zu behandeln. Ihre Phase-1-Studie, die im März 2021 abgeschlossen wurde, zeigte Sicherheit und Verträglichkeit, wobei sechs Teilnehmer eine vollständige Reaktion erzielten. Aktuell rekrutiert eine Phase-2-Studie 60 Patienten an neun Standorten in den USA, um zwei Dosisniveaus gegen ein Placebo zu bewerten.
- Phase 1 trial demonstrated complete response in six participants
- Phase 2 clinical trial actively recruiting at nine U.S. sites
- Strengthened executive team with experienced pharmaceutical industry leaders
- Successfully completed FDA safety and tolerability study
- None.
Promotes Edward Brennan, MD, FACS to Chief Scientific Officer & Head of R&D Program
TORONTO and PHILADELPHIA, Nov. 18, 2024 (GLOBE NEWSWIRE) -- Medicus Pharma Ltd (NASDAQ: MDCX TSXV: MDCX) (the “Company”) is pleased to announce the appointment of Faisal Mehmud, MD as Chief Medical Officer.
“We are thrilled to welcome Dr. Mehmud to our leadership team,” stated Dr. Raza Bokhari, Exec. Chairman & CEO. “Faisal has a proven track record in integrating cutting-edge science with practical, evidence-based medical strategies to develop partnerships and launch high impact therapies. We aim to capitalize on his experience and expertise to expand our drug development pipeline and foster collaboration with strategic partners to bring to market our novel non-invasive patented dissolvable doxorubicin-containing microneedle array (D-MNA) to treat non melanoma skin cancer, especially basal cell carcinoma.”
Dr. Mehmud brings over 20 years of global experience as a senior medical executive in clinical development, medical affairs, and drug safety across various therapeutic areas, including oncology, hematology, rare diseases, and primary care. He has played a central role in multiple successful launches of new medicines and has spearheaded innovative global medical lifecycle management strategies including for small molecules, antibodies, cell therapies and cytotoxic chemotherapies. His expertise encompasses late-phase development, product launch, and the seamless integration of new therapies into treatment pathways, all with a focus on improving patient outcomes through forward thinking clinical development plans. Dr. Mehmud’s career includes senior roles at leading pharmaceutical companies such as Sanofi, Novartis, Bristol Myers Squibb (BMS), Pfizer, and GlaxoSmithKline (GSK) based in London, Paris and Philadelphia.
Most recently, Dr. Mehmud was the Senior Vice President, Data Generation and Scientific Communications in Worldwide Global Medical Affairs at GlaxoSmithKline (LSE/NYSE:GSK), which included leadership of medical affairs sponsored and supported, interventional and non-interventional clinical trials. Before GSK, Dr. Mehmud was with Pfizer Inc., where he served in various roles including as Vice President and Worldwide Medical Franchise Head for Precision Medicine and Early Oncology Development, advancing the precision medicine oncology portfolio in a variety of tumor types, and supporting early-stage oncology projects moving from early clinical development to full development and market readiness, effectively bridging scientific innovation with commercial strategy.
Dr. Mehmud has also held leadership roles at Bristol Myers Squibb, including as Vice President in global drug safety, where he oversaw the safety risk management of complex therapies, including antibody-based treatments and cellular therapies.
Dr. Mehmud completed a medical degree from the University of Cambridge, as well as diplomas in internal medicine and pharmaceutical medicine from the Royal College of Physicians and holds a medical license with the UK General Medical Council.
The company also announced the promotion of Edward J. Brennan, MD, FACS, to Chief Scientific Officer and Head of R&D program. Dr. Brennan, who was mostly recently the company’s Chief Medical Officer, is a veteran pharmaceutical industry leader with extensive experience in all phases of clinical development across multiple therapeutics areas.
“Dr. Brennan, as a co-founder of the company, has been instrumental in identifying our lead asset D-MNA and designing the clinical development program to position us to not only become the first in class but also the best-in-class novel therapeutic alternative to treat BCC,” stated Dr. Raza Bokhari, Exec. Chairman & CEO. “Ed is an accomplished biopharmaceutical executive and his elevation to the role of Chief Scientific officer is very timely as we strengthen our executive team and gallop forward our D-MNA phase 2 study.”
Dr. Brennan has over 30 years of drug development experience. He has held senior medical leadership roles at major companies, including Wyeth, GlaxoSmithKline, and IndiPharm. As Medical Director at Wyeth and GSK, Dr. Brennan led clinical development programs that resulted in 10 FDA drug approvals. He oversaw teams responsible for all phases of clinical research as well as interactions with regulatory authorities. His therapeutic expertise includes Immunology, Oncology, Women's Health, and Genetic Diseases. Before industry roles, Dr. Brennan practiced medicine as a general surgeon.
Dr. Brennan received his undergraduate Bachelor of Science Degree in Pharmacy from Philadelphia College of Pharmacy and Science. He went on to study Medicine at the Royal College of Surgeons in Ireland before receiving his medical degree from Temple University School of Medicine.
For further information contact:
Carolyn Bonner, President
(610) 636-0184
cbonner@medicuspharma.com
Jeremy Feffer
LifeSci Advisors
(212) 915-2568
jfeffer@lifesciadvisors.com
About Medicus Pharma Ltd:
Medicus Pharma Ltd. (Nasdaq: MDCX, TSXV: MDCX) is a biotech/life sciences company focused on accelerating the clinical development programs of novel and disruptive therapeutics assets.
SkinJect Inc. a wholly owned subsidiary of Medicus Pharma Ltd, is a development stage, life sciences company focused on commercializing novel, non-invasive treatment for basal cell skin cancer using patented dissolvable microneedle patch to deliver chemotherapeutic agent to eradicate tumors cells. The Company has completed a phase 1 safety & tolerability study (SKNJCT-001) in March of 2021, which met its primary objective of safety and tolerability; the study also describes the efficacy of the investigational product D-MNA, with six (6) participants experiencing complete response on histological examination of the resected lesion. The Company submitted a Phase 2 IND clinical protocol to the FDA in January 2024 for a randomized, controlled, double-blind, multicenter clinical study (SKNJCT-003) that is expected to randomize up to 60 patients. The study is designed to evaluate the efficacy of two dose of two dose levels (100 and 200 ug) of D-MNA compared to placebo (P-MNA) in subjects with nodular BCC. Patient recruitment is currently underway in nine sites across the United States.
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FAQ
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