Mustang Bio, Inc. - MBIO STOCK NEWS

Mustang Bio, a clinical-stage biopharmaceutical company focused on cell and gene therapies, will host a webinar on December 16, 2021, at 2:30 p.m. ET. The event will present interim results from the Phase 1/2 clinical trial of MB-106, a CD20-targeted CAR T cell therapy for B-cell non-Hodgkin lymphomas and chronic lymphocytic leukemia. Dr. Mazyar Shadman from Fred Hutch will lead the discussion, with a Q&A session to follow. Mustang's IND was accepted by the FDA to initiate this trial, aimed at evaluating the safety and efficacy of MB-106 in patients with relapsed or refractory conditions.

Mustang Bio, Inc. (NASDAQ: MBIO) reported Q3 financial results, showing a net loss of $17.0 million ($0.19/share), up from $13.0 million ($0.23/share) a year earlier. Cash and equivalents totaled $121.9 million, down from $130.9 million in Q2 2021. Significant advancements include promising data from MB-106 CD20-targeted CAR T therapy, achieving a 94% overall response rate. The company secured a $2 million grant from the NCI to support MB-106 and received PRIME designation for MB-107 from the EMA. Upcoming presentations and trials are anticipated to further validate their therapies.

Mustang Bio has signed an exclusive license agreement with Leiden University Medical Centre for a first-in-class ex vivo lentiviral gene therapy targeting RAG1 severe combined immunodeficiency (RAG1-SCID). This therapy is currently in a Phase 1/2 clinical trial in Europe, with the first patient enrolled. The RAG1-SCID program has received Orphan Drug Designation by the European Medicines Agency. Mustang's ongoing development of lentiviral gene therapies aims to address significant unmet needs in treating SCID, which affects nearly 60% of cases.

Mustang Bio (NASDAQ: MBIO) announced interim Phase 1/2 data on MB-106, a CD20-targeted CAR T cell therapy for relapsed or refractory B-cell non-Hodgkin lymphomas and chronic lymphocytic leukemia, to be presented at the 63rd ASH Annual Meeting on December 11-14, 2021. The treatment showed an overall response rate of 94% and a complete response rate of 62% among the 16 patients studied. No dose-limiting toxicities were recorded. Additionally, a webinar is scheduled for December 16, 2021, to discuss the updated results and future plans regarding the therapy.

Mustang Bio, Inc. (NASDAQ: MBIO) has received a $2 million grant from the National Cancer Institute to support a Phase 1 clinical trial of MB-106, a CAR T cell therapy targeting B-cell non-Hodgkin lymphomas and chronic lymphocytic leukemia. The trial aims to assess the treatment's safety and efficacy. Additionally, Mustang has obtained Federalwide Assurance approval, ensuring compliance with U.S. regulations for human research protection. The funding and approvals represent significant steps in advancing Mustang's therapeutic offerings in hematologic cancers.

Mustang Bio, a clinical-stage biopharmaceutical company (NASDAQ: MBIO), announced its participation in Chardan’s Virtual 5th Annual Genetic Medicines Conference on October 5, 2021, at 8:00 a.m. ET. Manuel Litchman, M.D., President and CEO, and the leadership team will engage in a fireside chat, with a live webcast available on Mustang's Investor Relations page for 30 days post-event. Mustang focuses on cell and gene therapies targeting hematologic cancers, solid tumors, and rare genetic diseases, and is partnered with leading medical institutions for CAR T therapies and lentiviral gene therapy.

Mustang Bio (NASDAQ: MBIO) announced that Christine Brown, Ph.D. will present updated Phase 1 clinical data on MB-101 (IL13Rα2‐targeted CAR T cells) at two major cancer conferences in October 2021. The first presentation, titled 'CAR T Cells in Primary Brain Tumors', will take place on October 1, 2021, at the First Annual Conference on CNS Clinical Trials. The second presentation, 'Advancing CAR T Cell Therapy for Glioblastoma', is scheduled for October 25, 2021, at the AACR Virtual Special Conference on Brain Cancer. These presentations focus on innovative treatments for brain cancer.

Mustang Bio, Inc. (NASDAQ: MBIO), a biopharmaceutical company focused on cell and gene therapies, announced participation in three virtual investor conferences in September 2021. CEO Manuel Litchman will present at the H.C. Wainwright 23rd Annual Global Investment Conference on September 13, the Oppenheimer Fall Healthcare Life Sciences & MedTech Summit on September 20, and the Cantor Global Healthcare Conference on September 27. Webcasts of the presentations will be available on Mustang's website for about 30 days after the events.

Mustang Bio (NASDAQ: MBIO) reported financial results for Q2 2021, highlighting continued progress in CAR T and gene therapies. Key achievements included a 93% overall response rate and 67% complete response rate for MB-106 in high-risk B-NHL and CLL.

The FDA accepted IND for MB-106, with the first patient enrollment expected soon. Mustang secured an exclusive license for innovative CAR T technology and received PRIME designation from the EMA for MB-107. The company reported cash equivalents of $130.9 million and a reduced net loss of $14.4 million, or $0.16 per share.