Welcome to our dedicated page for Mustang Bio news (Ticker: MBIO), a resource for investors and traders seeking the latest updates and insights on Mustang Bio stock.
Mustang Bio Inc (MBIO) is a clinical-stage biopharmaceutical company advancing novel cancer immunotherapies and gene therapies. This dedicated news hub provides investors and researchers with timely updates on clinical developments, regulatory milestones, and strategic partnerships.
Access authoritative information on MBIO's CAR T-cell therapy programs, licensing agreements, and research collaborations with leading institutions like City of Hope. Our curated collection includes earnings reports, trial data disclosures, and management commentary – all essential for evaluating the company's progress in treating hematologic cancers and rare genetic disorders.
Key updates cover Phase 1/2 trial results, FDA designations, technology licensing deals, and scientific presentations. Bookmark this page to monitor Mustang Bio's advancements in engineered cell therapies and its position within the competitive oncology biotech landscape.
Mustang Bio, a clinical-stage biopharmaceutical company (NASDAQ: MBIO), announced its CEO, Manuel Litchman, will participate in three upcoming virtual investor conferences in January 2021. These include the 10th Annual LifeSci Partners Corporate Access Event from January 6-14, the H.C. Wainwright Virtual BioConnect Conference on January 11, and the B. Riley Securities’ Virtual Oncology Investor Conference on January 21. Presentations will be available on Mustang's website for 30 days following the events. Mustang focuses on cell and gene therapies for cancers and rare diseases.
Mustang Bio (NASDAQ: MBIO) has initiated a Phase 1 clinical trial at City of Hope to evaluate the safety and feasibility of MB-101 (IL13Rα2-CAR T cells) in treating patients with leptomeningeal brain tumors, including glioblastoma, ependymoma, and medulloblastoma. The trial will involve up to 30 patients and will assess toxicity and survival at three months, with additional secondary endpoints. The therapy previously showed promising results, including a complete response in a glioblastoma patient. The trial aims to provide a potential new treatment for these difficult-to-treat cancers.
Mustang Bio (NASDAQ: MBIO) presented promising interim data for MB-106, a CD20-targeted CAR T cell therapy, at the 62nd ASH Annual Meeting. The therapy showcased an impressive 89% overall response rate and a 44% complete response rate among nine patients with relapsed or refractory B-cell non-Hodgkin lymphoma. Safety data indicated no neurotoxicity and low incidence of cytokine release syndrome. Mustang plans to file an Investigational New Drug application in Q1 2021 to start a Phase 2 trial, expanding eligibility to include chronic lymphocytic leukemia patients.
Mustang Bio (NASDAQ: MBIO) will host a key opinion leader call on December 9, 2020, at 1:00 p.m. EST to present interim Phase 1/2 data on MB-106, an innovative CAR T cell therapy targeting relapsed or refractory B-cell non-Hodgkin lymphoma. The call will feature Drs. Mazyar Shadman and Brian Till from Fred Hutchinson Cancer Research Center, discussing clinical findings and a modified cell manufacturing process. Additionally, Mustang will provide a corporate update and address audience questions following the presentations.
Mustang Bio (NASDAQ: MBIO) received a positive opinion from the European Commission for Orphan Drug Designation for its lentiviral gene therapy targeting X-linked severe combined immunodeficiency (XSCID). This designation applies to both MB-107 and MB-207 therapies. Key advantages include protocol assistance and 10 years of market exclusivity in the EU. Mustang is preparing for pivotal clinical trials for these treatments and expects to initiate them soon. Additionally, an agreement with Minaris Regenerative Medicine enables GMP manufacturing for clinical trials in Europe.
Mustang Bio (NASDAQ: MBIO) has partnered with Minaris Regenerative Medicine for the GMP clinical manufacturing of its MB-107 lentiviral gene therapy targeting X-linked severe combined immunodeficiency (XSCID) in Europe. The collaboration will facilitate technology transfer and support clinical trials for this rare genetic disorder, which affects 1 in 225,000 births. MB-107 is currently in Phase 1/2 trials in the U.S. with plans for a pivotal trial in Europe. Mustang aims to provide this therapy to patients internationally, targeting topline data by late 2022.
Mustang Bio, Inc. (NASDAQ: MBIO) reported its third-quarter financial results for 2020, highlighting significant regulatory achievements. The FDA granted Rare Pediatric and Orphan Drug Designations for its gene therapy candidates MB-107 and MB-207 to treat X-linked severe combined immunodeficiency (XSCID). Mustang noted promising clinical progress in CAR T cell therapies, particularly with MB-106, showing efficacy without toxicity in non-Hodgkin lymphoma patients. Financially, Mustang's cash reserves decreased from $86.4 million to $76.3 million year-over-year, and the net loss increased to $13.0 million, or $0.23 per share.
Mustang Bio (NASDAQ: MBIO) announced that interim data on MB-106, a CAR T cell therapy for relapsed or refractory B-cell non-Hodgkin lymphoma, will be presented at the 62nd ASH Annual Meeting. The data includes responses from four patients treated after a manufacturing revision, showing two complete and one partial remission. The therapy demonstrated an encouraging safety profile, with no dose-limiting toxicities and only one case of cytokine release syndrome. Mustang aims to provide further updates on additional patients treated since the revision.
Mustang Bio (NASDAQ: MBIO) announced the presentation of promising data from a Phase 1 trial on MB-105, a CAR T therapy targeting prostate cancer. Conducted by Dr. Tanya Dorff at City of Hope, the trial showed a remarkable 94% reduction in prostate-specific antigen (PSA) in a 73-year-old male patient after failing eight prior therapies. The treatment resulted in near-complete reduction of metastasis and was manageable regarding cytokine release syndrome. Mustang's CEO expressed optimism for further trial progress and additional data expected in 2021.
Mustang Bio, Inc. (NASDAQ: MBIO) announced that initial Phase 1 data on their PSCA-targeted CAR T therapy, MB-105, will be presented at the virtual 27th Annual Prostate Cancer Foundation Scientific Retreat from October 20-23, 2020. This therapy targets patients with PSCA-positive metastatic castration-resistant prostate cancer (mCRPC). The Phase 1 trial can enroll up to 33 patients, focusing on side effects and optimal dosing, with secondary endpoints assessing treatment response and survival outcomes. The data presentation will take place on October 23, 2020.
