Lyell Immunopharma, Inc. - LYEL STOCK NEWS

Lyell Immunopharma (Nasdaq: LYEL) is set to participate in the BofA Securities 2022 Biotech SMID Cap Conference on December 8, 2022, at 1:40 pm ET. The event will feature members of its senior management team, and a live webcast will be available on the company's website. This opportunity highlights Lyell's commitment to developing curative cell therapies for solid tumors, leveraging proprietary technologies to overcome key barriers in adoptive T-cell therapy. A replay of the webcast will be accessible for 90 days post-event.

Lyell Immunopharma, Inc. (Nasdaq: LYEL), a clinical-stage T-cell reprogramming company, announced participation in the Barclays Virtual Fireside Chat Series on November 17 at 11 a.m. ET. The event will feature senior management discussing advancements in curative cell therapies for solid tumors. A webcast of the presentation can be accessed on the company's investor relations website, with a replay available for 90 days afterwards. Lyell focuses on overcoming challenges in adoptive T-cell therapy through innovative genetic and epigenetic reprogramming technologies.

Lyell Immunopharma, Inc. (Nasdaq: LYEL) announced FDA clearance of the IND for LYL845, advancing its TIL product candidate into clinical development. As of September 30, 2022, the company reported cash equivalents of $750.7 million, extending its financial runway into 2026. Revenue dipped to approximately zero in Q3 2022, down from $2.8 million in Q3 2021, reflecting no R&D under the GSK Agreement. The net loss increased to $70.3 million compared to $48.9 million year-over-year. Lyell is expected to present initial data for LYL845 in 2024.

Lyell Immunopharma (Nasdaq: LYEL) is presenting preclinical research at the 37th Annual Meeting of the Society for Immunotherapy of Cancer, showcasing advancements in T-cell therapies targeting solid tumors. Key highlights include:

• LYL845 exhibits a 100% expansion success rate using Epi-R technology.
• Research indicates LYL845 maintains T-cell polyclonality and stem-like properties, enhancing anti-tumor efficacy.
• Innovative stackable reprogramming technologies are being developed for LYL119 to improve CAR T-cell therapies.

These findings aim to address T-cell exhaustion and enhance treatment outcomes in cancer patients.

Lyell Immunopharma (Nasdaq: LYEL) announced that its senior management will present at the Credit Suisse 31st Annual Healthcare Conference on November 9, 2022, at 2:00 p.m. ET. The presentation will focus on the company’s innovative T-cell reprogramming technologies aimed at developing curative cell therapies for solid tumors. A live webcast will be available on the company's investor relations website, with a replay accessible for 90 days after the event.

Lyell Immunopharma has received FDA clearance for its Investigational New Drug (IND) application to initiate a Phase 1 clinical trial for LYL845, a tumor infiltrating lymphocyte (TIL) therapy utilizing Lyell’s proprietary Epi-R technology. This trial will focus on patients with relapsed or refractory melanoma, expanding later to include non-small cell lung cancer and colorectal cancer. Initial data presentation is anticipated in 2024. This marks Lyell's second product candidate to receive IND clearance within the last year, showcasing progress in its mission to develop curative T-cell therapies.

Lyell Immunopharma (LYEL) announced its participation at the 37th Annual Meeting of the Society for Immunotherapy of Cancer (SITC) with five accepted abstracts highlighting new preclinical data. This data focuses on T-cell reprogramming technologies incorporated in LYL119, an investigational ROR1 targeting CAR T-cell therapy. The findings aim to enhance T cell functionality and combat exhaustion in solid tumors, showcasing Lyell's efforts in advancing its therapeutic pipeline to improve patient outcomes in adoptive cell therapy.

Lyell Immunopharma, Inc. (Nasdaq: LYEL) announced the appointment of Rahsaan W. Thompson as chief legal officer, enhancing its executive management team. Thompson, an industry veteran with over 20 years of experience in corporate law, previously served at Gritstone bio and Actelion Pharmaceuticals. CEO Liz Homans emphasized Thompson's expertise as a boon for advancing clinical developments targeting solid tumors. Lyell is dedicated to curative cell therapies and is applying innovative reprogramming technologies to improve patient outcomes.

Lyell Immunopharma (Nasdaq: LYEL) announces the presentation of a poster at the ESMO Congress 2022 on the Phase 1 trial design for LYL797, a CAR T-cell therapy aimed at treating solid tumors. This innovative therapy utilizes Lyell’s Gen-R™ and Epi-R™ technologies to enhance T-cell functionality against challenges like exhaustion. The trial targets patients with advanced solid tumors, including triple-negative breast cancer and non-small cell lung cancer. The poster session occurred on September 12, 2022, in Paris, providing insights into Lyell's commitment to curative cell therapies.