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Lixte Biotechnology Holdings, Inc. (symbol: LIXT) is a clinical-stage biopharmaceutical company focused on developing innovative treatments for cancer. The company has made significant strides in identifying molecular signaling pathways that are altered in various disease states. By designing compounds that can safely target these pathways in animal models, Lixte aims to enhance the effectiveness of existing cancer treatments.
The company's drug portfolio includes inhibitors of protein phosphatases and protein deacetylases. These inhibitors are crucial for cell division, DNA damage repair, and the regulation of gene expression and protein degradation. The phosphatase inhibitors, in particular, have shown potential in increasing the efficacy of cytotoxic anti-cancer drugs and radiation therapy. This makes them potentially useful for the treatment of a wide range of cancers when used in combination with standard chemotherapy regimens and emerging targeted therapies.
Lixte's lead compound, LB-100, is currently in Phase I trials and has the potential to be a first-in-class treatment. LB-100 has shown promising clinical anti-cancer activity with minimal toxicity. This compound is being developed as a protein phosphatase 2A inhibitor and has potential applications in combination with cytotoxic agents, x-rays, immune checkpoint blockers, and other cancer therapies.
In addition to its primary focus on protein phosphatase inhibitors, Lixte is exploring the therapeutic potential of protein deacetylase inhibitors. These inhibitors are involved in regulating gene expression and protein degradation pathways, offering another avenue for cancer treatment development.
Lixte Biotechnology Holdings, Inc. continues to make significant advancements in cancer research, aiming to provide more effective treatment options for patients worldwide. The company's ongoing projects, strategic partnerships, and innovative drug portfolio position it as a key player in the biopharmaceutical industry.
Lixte Biotechnology Holdings, Inc. (Nasdaq: LIXT) has completed a Registered Direct Offering of $4.19 million in common stock, issuing 1,133,102 shares at $3.70 each. This offering was facilitated by WestPark Capital, which acted as Co-Placement Agent. The shares were issued under a previously filed shelf registration statement with the SEC. This funding aims to bolster Lixte’s clinical-stage drug development focused on cancer treatment and other serious diseases, indicating potential for growth in their innovative therapeutic pipeline.
WallachBeth Capital has successfully completed a $4.19 million Registered Direct Offering for Lixte Biotechnology Holdings (LIXT). A total of 1,133,102 shares of common stock were sold at $3.70 per share. The net proceeds will support working capital and further development of the lead clinical compound LB-100.
The offering was made under a previously filed shelf registration statement. The company is focused on innovative cancer treatment solutions, with LB-100 currently undergoing clinical trials.
Lixte Biotechnology Holdings, Inc. (Nasdaq: LIXT) announced the completion of a registered direct offering, raising approximately $4.19 million through the sale of 1,133,102 shares of common stock at $3.70 per share. The funds will be allocated for working capital and further development of its lead clinical compound, LB-100. WestPark Capital, Inc. and WallachBeth Capital, LLC served as co-placement agents for this transaction.
Lixte Biotechnology Holdings, Inc. (Nasdaq: LIXT) announced a direct offering of 1,133,102 shares of common stock at $3.70 per share, expected to generate approximately $4.19 million in gross proceeds. The funds will support working capital and the development of its lead compound, LB-100, which targets cancer treatment. The transaction is facilitated by WestPark Capital, Inc. and WallachBeth Capital, LLC, with the offering closing on or about March 2, 2021, pending customary conditions. The offering is conducted under a previously effective shelf registration statement.
Lixte Biotechnology Holdings, Inc. (Nasdaq: LIXT) announced its participation in the H.C. Wainwright Global Life Sciences Conference on March 9-10, 2021. CEO John S. Kovach will present the company's first-in-class compound, LB-100, which targets cancer treatment by enhancing the efficacy of standard therapies while minimizing toxicity. LB-100 is currently undergoing clinical studies across four cancer indications: Myelodysplastic Syndromes, Advanced Soft Tissue Sarcoma, Small Cell Lung Cancer, and Glioblastoma Multiforme. A webcast of the presentation will be available on the company's website.
Lixte Biotechnology Holdings, Inc. (NASDAQ: LIXT) has announced an agreement to conduct a Phase 1b clinical trial with City of Hope, focusing on the combination of its protein phosphatase inhibitor, LB-100, with a standard chemotherapy regimen for extensive stage disease small cell lung cancer (ED-SCLC). The trial aims to assess LB-100’s safety and therapeutic activity when combined with carboplatin, etoposide, and atezolizumab. LB-100 has shown promise in animal models by enhancing chemotherapy's antitumor effects without added toxicity.
On December 1, 2020, WallachBeth Capital announced the completion of a joint underwritten public offering for Lixte Biotechnology Holdings, Inc. (LIXT). The offering involved 1,200,000 shares priced at $4.75 each, generating gross proceeds of $5.7 million. Each unit comprises one share of common stock and one warrant with an exercise price of $5.70. The option for underwriters to purchase an additional 180,000 shares exists. Trading for these securities commenced on November 25, 2020, and this offering is filed under an effective SEC registration statement.
Lixte Biotechnology Holdings has completed a public offering of 1,200,000 units at a price of $4.75 per unit, totaling $5.7 million in gross proceeds. Each unit comprises one share of common stock and one warrant at an exercise price of $5.70. The offering, which closed on December 1, 2020, included an option for underwriters to purchase an additional 180,000 shares and/or warrants.
The securities began trading separately on the Nasdaq Capital Market on November 25, 2020.
Lixte Biotechnology Holdings, Inc. has successfully closed a follow-on offering, selling 1,200,000 units at $5,700,000 in total gross proceeds. Each unit comprises one share of common stock and one warrant. The offering, managed by WestPark Capital, Inc., is part of an effective registration statement filed with the SEC. The company, trading on Nasdaq under the symbols LIXT and LIXTW, focuses on innovative drug discovery targeting enzyme-related diseases, with a pipeline aimed at both cancer and other serious health conditions.
Lixte Biotechnology Holdings, Inc. (NASDAQ: LIXT) announced a public offering of 1,200,000 units priced at $4.75 per unit, each consisting of one share of common stock and one warrant. The warrants are exercisable at $5.70, expiring in five years. The offering, following a reverse stock split of 1-for-6, aims to raise approximately $5.7 million for clinical trials, patent extensions, and general corporate purposes. The offering is expected to close around November 30, 2020, with underwriters granted an option for an additional 180,000 shares or warrants.
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