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Legend Biotech Corp - LEGN STOCK NEWS

Welcome to our dedicated page for Legend Biotech news (Ticker: LEGN), a resource for investors and traders seeking the latest updates and insights on Legend Biotech stock.

Overview of Legend Biotech Corp

Legend Biotech Corp (NASDAQ: LEGN) is a clinical-stage biopharmaceutical company dedicated to harnessing cutting-edge cell therapy and CAR-T immunotherapy technologies to revolutionize the treatment of cancer, particularly multiple myeloma and other oncology indications. With a robust pipeline of chimeric antigen receptor (CAR) product candidates, the company leverages advanced scientific research and decades of expertise in molecular biology and immunology to address previously unmet medical needs in oncology.

Core Business and Strategic Focus

The core business of Legend Biotech revolves around the discovery, development, and clinical application of next-generation cell therapies. The company utilizes its proprietary platforms to develop CAR-T cell therapies that are designed to target and eliminate malignant cells in patients with liquid and solid tumors. By focusing on cancers that have long been considered incurable, such as multiple myeloma, Legend Biotech aims to improve treatment outcomes and extend patient survival. The company generates revenue through strategic licensing and collaboration agreements, partnering with established industry players to expand the reach of its innovative therapies.

Research, Development, and Innovation

Legend Biotech is recognized for its commitment to research and development. The company operates multiple R&D sites around the globe, ensuring a diverse and comprehensive approach to clinical research. Its teams of immunologists and molecular biologists work collaboratively to fine-tune CAR-T cell constructs and other cell-based therapies. This rigorous R&D approach has resulted in a strong pipeline of product candidates that undergo extensive clinical trials, with several therapies demonstrating promising efficacy in early and advanced stages of clinical evaluation.

Technology Platform and Pipeline

The company’s technology platform is built on the complex science of cellular engineering, enabling the development of both autologous and allogeneic cell therapies. These therapies often involve the genetic modification of a patient’s own immune cells to enhance their ability to recognize and kill cancer cells. A key product in its portfolio is a BCMA-targeted CAR-T cell therapy, which has shown significant clinical potential in treating relapsed or refractory multiple myeloma. This approach not only refines the patient’s immune response but also opens avenues for additional therapeutic applications across various oncologic disorders.

Market Position and Collaborative Strength

Within the competitive landscape of biopharmaceutical innovation, Legend Biotech positions itself as a vital contributor to the next generation of cancer treatment. The company’s involvement in high-profile clinical trials and its collaboration with major industry partners underscore its authoritative presence in the field. Its licensing and collaboration agreements with renowned organizations further reinforce its scientific credibility and operational robustness, positioning the company as an important player in global oncology research and treatment development.

Pipeline and Clinical Impact

Legend Biotech’s pipeline reflects its dedication to transforming cancer treatment paradigms. The company’s clinical trials have evaluated the safety and efficacy of its CAR-T therapies among diverse patient groups. These studies are designed to demonstrate not only impressive clinical responses but also enhancements in overall survival and quality of life among patients with challenging oncologic diagnoses. By rigorously testing its product candidates in multiple clinical settings, Legend Biotech contributes valuable data to the scientific community and paves the way for the broader adoption of cell therapies in routine clinical practice.

Scientific Rigor and Regulatory Engagement

Undergirding its product development is a strong commitment to scientific rigor and regulatory compliance. Legend Biotech adheres to strict quality standards in the development and manufacturing of its therapies, ensuring both efficacy and patient safety. Its active engagement with regulatory bodies worldwide reflects a proactive approach to meeting global standards, thereby enhancing the trust of both patients and healthcare providers in its therapies.

Commitment to Advancing Oncology Treatment

At its core, Legend Biotech is driven by the vision of overcoming the long-standing challenges in cancer treatment. By advancing the science of cell therapies, the company seeks to offer novel, potentially transformative treatments that redefine the standard of care in oncology. Its comprehensive approach, which integrates innovative research, deep scientific expertise, and strategic collaborations, enables Legend Biotech to contribute meaningfully to the evolving landscape of immunotherapy and personalized medicine.

Key Highlights

  • Innovative Cell Therapies: Focused on CAR-T cell therapies for addressing difficult-to-treat cancers, especially in the field of oncology.
  • Advanced R&D: Multiple research centers globally support expansive R&D efforts and clinical trials.
  • Collaborative Revenue Model: Strategic licensing and collaboration agreements enhance scientific advancement and market reach.
  • Clinical Expertise: Demonstrated capabilities in conducting rigorous clinical trials and generating actionable clinical data.
  • Regulatory Engagement: Active interactions with regulatory agencies ensure adherence to high quality and safety standards.

Conclusion

Legend Biotech Corp stands as a formidable entity in the field of biotechnology, focusing on the development of best-in-class immunotherapies. Through its innovative cell therapy platforms and robust clinical research programs, the company is committed to revolutionizing cancer treatment and improving patient outcomes in oncology. Its deep scientific expertise, combined with a strategic approach to R&D and global collaborations, solidifies its reputation as an authoritative and trustworthy source in the biopharmaceutical landscape.

Rhea-AI Summary

Legend Biotech Corporation (NASDAQ: LEGN) received a notice from Nasdaq on January 6, 2023, indicating non-compliance with Listing Rules due to a failure to file the interim balance sheet and income statement for the quarter ended June 30, 2022. The deadline for compliance was December 31, 2022, which has not been met due to a planned restatement of prior financial statements. The company has 60 days from the notice to submit a compliance proposal, with a potential extension to June 29, 2023, if accepted.

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Legend Biotech Corporation (NASDAQ: LEGN) has announced its participation in the 41st annual JP Morgan Healthcare Conference in San Francisco, CA. CEO Ying Huang, PhD, will present on Tuesday, January 10, 2023, at 2:15 PM Pacific Time. The company is focused on developing novel therapies for life-threatening diseases, leveraging advanced cell therapies, including CAR T-cell and NK cell-based immunotherapy. Legend Biotech, headquartered in Somerset, New Jersey, strives to discover cutting-edge therapeutics globally.

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Legend Biotech Corporation (NASDAQ: LEGN) announced the acceptance of its New Drug Application (NDA) for ciltacabtagene autoleucel (cilta-cel) by China's NMPA. This application is based on the CARTIFAN-1 Phase 2 clinical study data, focusing on patients with relapsed or refractory multiple myeloma who have undergone multiple prior therapies. The study indicated significant efficacy and safety of cilta-cel, addressing a critical unmet medical need due to rising incidence rates of multiple myeloma in China. Cilta-cel is already approved in the U.S., Japan, and has conditional authorization in Europe.

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Legend Biotech Corporation (NASDAQ: LEGN) has announced its participation in several upcoming investor conferences. The events include the BMO Biopharma Spotlight Series: Oncology Day on November 9, 2022, and the Cowen 6th Annual IO Next Summit on November 11, 2022, both featuring presentations by CEO Ying Huang, Ph.D. Further conferences will take place in Miami on November 14, London on November 17, and New York on November 29, culminating with the Evercore ISI 5th Annual HealthCONx Conference on November 30, 2022.

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Legend Biotech Corporation (NASDAQ: LEGN) announced that seven studies on its CAR-T therapy, ciltacabtagene autoleucel (cilta-cel), have been accepted for presentation at the 64th American Society of Hematology (ASH) Annual Meeting. This includes data on sustained minimal residual disease negativity from the pivotal CARTITUDE-1 study and the first presentation of CARTIFAN-1 study results in heavily pretreated Chinese patients. Presentations will highlight ongoing clinical development and long-term follow-up data, reaffirming the potential of cilta-cel to significantly impact multiple myeloma treatment.

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Legend Biotech Corporation (NASDAQ: LEGN) has received approval from Japan’s Ministry of Health for its CAR-T therapy, CARVYKTI™ (ciltacabtagene autoleucel), aimed at treating adults with relapsed or refractory multiple myeloma. This therapy is limited to patients with no history of CAR-positive T cell therapy and those who have undergone three or more treatment lines. The approval is based on promising data from the pivotal CARTITUDE-1 study, where 96.9% of non-Japanese patients showed a response, with 67% achieving a stringent complete response.

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Legend Biotech Corporation (NASDAQ: LEGN) will host its in-person and virtual Research & Development Day on October 3, 2022, at 10:00 a.m. ET in New York City. The event aims to provide a comprehensive overview of the company's platforms and pipeline developments from its senior leadership team, including CEO Ying Huang and other key executives. A live webcast will be accessible, with a replay available within 24 hours post-event. Investors can register here.

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Legend Biotech Corporation (NASDAQ: LEGN) announced participation in several key investor conferences: Citi's 17th Annual BioPharma Conference on September 7, 2022, Wells Fargo Healthcare Conference on September 8, 2022, and the Morgan Stanley Global Healthcare Conference on September 12, 2022, all featuring CEO Ying Huang, Ph.D. Additionally, the company will attend the Jefferies Cell and Genetic Medicine Summit on September 29-30, 2022. Legend Biotech focuses on developing innovative therapies for life-threatening diseases from its headquarters in Somerset, New Jersey.

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Legend Biotech Corporation (NASDAQ: LEGN) reported preliminary, unaudited financial results for the six months ended June 30, 2022. The company anticipates a loss between US$196 million and US$228.9 million, primarily due to R&D investments in its lead product candidate, cilta-cel. An adjusted loss is expected between US$144.5 million and US$168.6 million. Additionally, a non-cash fair value loss of US$27.9 million to US$32.6 million from warrant liability changes is projected. As of June 30, 2022, cash and equivalents totaled approximately US$379.8 million.

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Legend Biotech Corporation (NASDAQ: LEGN) announced the appointment of three new directors to its Board: Mr. Tomas Heyman (Class I), Dr. Fangliang "Frank" Zhang (Class II), and Dr. Li Mao (Class III). The Board emphasized that these individuals possess essential skills for executing the company’s long-term strategy. Sally Wang resigned as Chair but will continue as a director. Dr. Zhang has been elected Chairman of the Board. The changes aim to strengthen leadership as the company advances its development of innovative therapies.

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FAQ

What is the current stock price of Legend Biotech (LEGN)?

The current stock price of Legend Biotech (LEGN) is $32.8 as of April 18, 2025.

What is the market cap of Legend Biotech (LEGN)?

The market cap of Legend Biotech (LEGN) is approximately 5.9B.

What is Legend Biotech Corp's core focus?

Legend Biotech focuses on developing innovative cell therapies, especially CAR-T immunotherapy, to treat challenging cancers like multiple myeloma.

How does Legend Biotech generate revenue?

The company generates revenue through strategic licensing and collaboration agreements, leveraging its innovative product pipeline and research advancements.

What distinguishes Legend Biotech's CAR-T therapies?

Their CAR-T therapies are designed using proprietary cellular engineering techniques to enhance immune cell targeting of malignant cells, demonstrating promising efficacy in clinical trials.

In which clinical areas does Legend Biotech operate?

Legend Biotech primarily operates in oncology, developing cell therapies for both liquid and solid tumors, with a significant focus on multiple myeloma.

What is the importance of the company’s R&D efforts?

Their global R&D facilities and teams of experts ensure a rigorous approach to clinical development, fostering innovation and maintaining high standards in therapeutic research.

How is Legend Biotech positioned in the global market?

Through strategic collaborations and robust clinical trial data, Legend Biotech has established itself as a respected and influential player in advanced cell therapy and cancer treatment.

What types of therapies does Legend Biotech develop?

The company develops both autologous and allogeneic cell therapies, with a strong focus on CAR-T cell therapy aimed at treating various forms of cancer.

How does Legend Biotech ensure the safety and quality of its therapies?

The company adheres to stringent quality control and regulatory standards, actively engaging with global regulatory bodies to ensure its therapies meet the highest safety and efficacy benchmarks.
Legend Biotech Corp

Nasdaq:LEGN

LEGN Rankings

LEGN Stock Data

5.88B
181.20M
1.33%
55.49%
7.14%
Biotechnology
Healthcare
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United States
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