Final Results for the year ended 31 December 2020
4D pharma plc (NASDAQ: LBPS) reported its financial results for 2020, highlighting total equity of £28 million, a cash increase to £8.8 million, and a comprehensive loss of £25.9 million. The company advanced the Live Biotherapeutic MRx0518, demonstrating clinical efficacy in oncology trials. Significant milestones included completion of a merger with Longevity Acquisition Corporation and a NASDAQ listing. The company raised approximately £30 million through fundraising. The AGM is scheduled for 24 May 2021, with a virtual attendance format to comply with UK Government guidelines.
- Increased total equity to £28 million from £22.3 million in 2019.
- Cash and cash equivalents rose to £8.8 million, up from £3.8 million in 2019.
- Successful merger with Longevity Acquisition Corporation, leading to NASDAQ listing.
- Raised approximately £30 million in gross proceeds through fundraising.
- Announced proof-of-concept data for MRx0518 in clinical trials.
- Total comprehensive loss increased from £23.7 million in 2019 to £25.9 million in 2020.
- Adjusted loss per share remains high at 22.80 pence.
Leeds, UK, April 01, 2021 (GLOBE NEWSWIRE) -- 4D pharma plc (AIM: DDDD, NASDAQ: LBPS) (“4D”, the “Company” or, together with its subsidiaries, the “Group”), a pharmaceutical company leading the development of Live Biotherapeutics, is pleased to announce the final results for the Group for the year ended 31 December 2020.
All details stated hereafter relate to the UK IFRS accounts; the Group also produces US GAAP accounts, the details of which are included in the Form 20-F to be filed with the U.S. Securities and Exchange Commission.
Financial highlights for the year:
| ● | Total equity of |
| ● | Cash and cash equivalents (including cash on deposit) of |
| ● | Loss for the year and total comprehensive income for the year of |
| ● | Adjusted loss per share of 22.80 pence (2019: 40.81pence) |
| ● | Basic and diluted loss per share of 22.80 pence (2019: 36.75 pence) |
Operational highlights
| ● | Announced safety and proof-of-concept clinical efficacy data for lead Live Biotherapeutic MRx0518 in combination with checkpoint inhibitor (ICI) Keytruda® in heavily pre-treated patients with non-small cell lung cancer and renal cell carcinoma refractory to prior ICIs |
| ● | Presented the first clinical monotherapy data for a Live Biotherapeutic in oncology with data from Part A of our clinical trial of MRx0518 in the neoadjuvant setting |
| ● | Launched a third clinical trial of MRx0518, in pancreatic cancer in combination with stereotactic radiotherapy |
| ● | Commencement and expansion of Part B of Phase I/II clinical trial of MRx0518 in combination with Keytruda®, with inclusion of additional tumor type cohorts and additional US sites added |
| ● | Phase II data for Blautix® showing clinical activity in irritable bowel syndrome with constipation (IBS-C) or with diarrhoea (IBS-D) |
| ● | Launch of a Phase II clinical trial of oral immuno-modulatory Live Biotherapeutic MRx-4DP0004 for the treatment of patients hospitalised with COVID-19 |
| ● | Completed two fundraises by way of a Placing and Subscription raising gross proceeds of approximately |
| ● | Entered into a proposed merger agreement with Longevity Acquisition Corporation (Longevity), a NASDAQ-listed Special Purpose Acquisition Company (SPAC), and announced intention to seek NASDAQ listing |
| ● | Appointment of Prof. Axel Glasmacher as Non-Executive Chairperson |
| ● | Appointment of Dr. Katrin Rupalla as an independent Non-Executive Director |
| ● | Appointment of Glenn Dourado as Chief Business Officer |
Since the period end
| ● | On 22 March 2021 the Company completed its previously announced merger with Longevity and the listing of its ADSs on NASDAQ became effective under the ticker ‘LBPS’; the following day 4D’s warrants began trading on NASDAQ under the ticker ‘LBPSW’ |
| ● | On 22 March 2021, the Company completed a |
| ● | On 1 March 2021 we announced the appointment of Paul Maier as an independent Non-Executive Director, and appointment of John Beck as Chief Financial Officer |
| ● | On 8 February 2021 we announced our second oncology clinical collaboration and drug supply agreement, with Merck KGaA and Pfizer, Inc. to evaluate MRx0518 in combination with ICI Bavencio® as a first-line maintenance therapy for urothelial carcinoma |
Prof. Axel Glasmacher, Chairman of 4D pharma, commented: “2020 was a transformational year for 4D: We were able to publish first proof-of-concept data for MRx0518 in last-line cancers and to initiate our NASDAQ listing. This creates a solid foundation for the next steps towards bringing live biotherapeutics to patients suffering from severe diseases. On behalf of the Board I would like to thank everyone at 4D for an exceptional performance under difficult circumstances.”
Duncan Peyton, Chief Executive Officer, commented: “4D has made significant progress leading the field in the development of Live Biotherapeutics, and made great strides from a corporate perspective. In addition to the data we have generated in the field of oncology, we completed our merger with Longevity and obtained a NASDAQ listing which, together with a concurrent fundraise, provides 4D with approximately
The Annual Report, together with a notice of the Company’s Annual General Meeting (“AGM”), will be posted to shareholders and made available on the Company’s website, www.4dpharmaplc.com, by 16 April 2021. The Annual General Meeting will be held at 10 a.m (BST) on Monday 24th May 2021 at 9 Bond Court, Leeds, LS1 2JZ. We continue to follow guidance from the UK Government which limits public gatherings. To prevent issues and remain compliant with the rules in force, persons, shareholders, advisers and other guests will not be allowed to attend the AGM and anyone seeking to attend the meeting in person will be refused entry. We therefore encourage shareholders to submit any questions they would like to pose to the Board to ir@4dpharmaplc.com so as to be received no later than Wednesday 19th May 2021 . All emails should be marked “AGM Question” in the subject line, and will require a shareholder number. If the UK Government’s guidance changes before the AGM and allows significant gatherings of people, we will notify you via the Company’s website at www.4dpharmaplc.com
Forward-Looking Statements
This announcement contains “forward-looking statements.” All statements other than statements of historical fact contained in this announcement, including without limitation statements regarding future results form our clinical trials including our move to the clinic with our Parkinsons and Bavencio trial, the effect of our recent capital raise on the financial footing of the Company, the timing for our shareholder mailing and meeting and the intent of certain of our Directors to invest in our ordinary shares are forward-looking statements within the meaning of Section 27A of the United States Securities Act of 1933, as amended (the “Securities Act”), and Section 21E of the United States Securities Exchange Act of 1934, as amended (the “Exchange Act”). Forward-looking statements are often identified by the words “believe,” “expect,” “anticipate,” “plan,” “intend,” “foresee,” “should,” “would,” “could,” “may,” “estimate,” “outlook” and similar expressions, including the negative thereof. The absence of these words, however, does not mean that the statements are not forward-looking. These forward-looking statements are based on the Company’s current expectations, beliefs and assumptions concerning future developments and business conditions and their potential effect on the Company. While management believes that these forward-looking statements are reasonable as and when made, there can be no assurance that future developments affecting the Company will be those that it anticipates.
All of the Company’s forward-looking statements involve known and unknown risks and uncertainties, some of which are significant or beyond its control, and assumptions that could cause actual results to differ materially from the Company’s historical experience and its present expectations or projections. The foregoing factors and the other risks and uncertainties that could cause actual results to differ materially include delays or changes to the nature and scope of our clinical trials, patient response rates, the effect of current and future pandemics, the timing and nature of future cash needs and those additional risks and uncertainties described the documents filed by the Company with the US Securities and Exchange Commission (“SEC”). The Company wishes to caution you not to place undue reliance on any forward-looking statements, which speak only as of the date hereof. The Company undertakes no obligation to publicly update or revise any of its forward-looking statements after the date they are made, whether as a result of new information, future events or otherwise, except to the extent required by law.
For further information please contact:
4D Pharma plc
Duncan Peyton, Chief Executive Officer + 44 (0)113 895 0130
Investor Relations ir@4dpharmaplc.com
N+1 Singer - Nominated Adviser and Joint Broker +44 (0) 20 7496 3000
Phil Davies / Iqra Amin / James Fischer (Corporate Finance) / Tom Salvesen (Corporate Broking)
Bryan Garnier & Co. Limited - Joint Broker +44 (0)20 7332 2500
Dominic Wilson / Phil Walker
Image Box PR
Neil Hunter / Michelle Boxall
Tel +44 (0)20 8943 4685
neil@ibcomms.agency / michelle@ibcomms.agency
www.4dpharmaplc.com]
Chairman and CEO’s statement
Introduction
4D pharma’s strategy continues to be to pioneer a novel class of safe and effective therapeutic derived from the gut microbiome – Live Biotherapeutic Products – and to selectively partner or potentially develop these through regulatory approval and subsequent commercialisation.
During the year, we made significant progress across our LBP clinical development programs. In April we announced the successful completion of the Part A safety phase of our Phase I/II clinical trial of lead immuno-oncology LBP candidate MRx0518 in combination with immune checkpoint inhibitor (ICI) Keytruda® (pembrolizumab) in patients with solid tumors refractory to prior ICI therapy. During Part A of this clinical trial, MRx0518 showed no treatment-related serious adverse effects or drug discontinuations and, importantly, no increase of immune-related adverse events that are often associated with ICI therapy. The safety review committee duly recommended to proceed to Part B of the study, which is ongoing.
In August, we announced comprehensive clinical benefit data from the 12 patients enrolled into Part A of the trial. Five patients (
At the Society for Immunotherapy of Cancer (SITC) Annual Meeting 2020 in November we announced the expansion of the Part B of this study, with the inclusion of three additional tumor type cohorts of triple-negative breast cancer, squamous cell carcinoma of the head and neck, and microsatellite instability high/mismatch repair deficient solid tumors, in addition to the previously enrolling cohorts of renal cell carcinoma, non-small cell lung cancer and bladder cancer.
In October 2020 we completed a Phase II clinical trial investigating the efficacy of Blautix® in the treatment of irritable bowel syndrome (IBS) which showed: (i) a statistically significant increase in overall response in pre-planned analysis of the combined IBS-C/D group compared to placebo; and (ii) a positive, though non-significant increase in overall response in both IBS-C and IBS-D cohorts, individually. The primary efficacy endpoint of the trial was based on whether or not a subject, from either the IBS-C or IBS-D cohorts, was considered an overall responder. For a subject to be classed as an ‘overall responder’ they must have reported an improvement in their weekly (cohort specific) symptoms (abdominal pain intensity and stool frequency or consistency) for ≥
In April 2020 we received MHRA acceptance for a UK Phase II clinical trial of our immuno-modulatory LBP MRx-4DP0004 in patients hospitalised with COVID-19. MRx-4DP0004 is in an ongoing Phase I/II clinical trial in asthma patients as an add-on therapy to existing long-term maintenance therapy.
In support of our efforts to advance LBP candidates into the clinic for the treatment of neurodegenerative diseases such as Parkinson’s disease, in December 2020 we became an industry partner of the Parkinson’s Progression Markers Initiative (PPMI), a longitudinal study sponsored by The Michael J. Fox Foundation for Parkinson’s Research to better understand Parkinson’s disease and accelerate the development of new treatments. 4D pharma representatives will join the Partner Scientific Advisory Board closely involved in the design and execution of the study, as well as a variety of PPMI Working Groups.
In the year we made good progress in our research collaboration with Merck Sharp & Dohme to discover and develop vaccines in up to three indications. To date, we have screened and characterised hundreds of LBPs with immuno-modulatory potential and selected from this group lead LBPs with desirable immuno-modulatory properties for further evaluation and development.
In addition to continued progress in advancing multiple development programs and therapeutic candidates, in October 2020 the Company entered a definitive merger agreement with Longevity Acquisition Corporation a publicly-traded special purpose acquisition company (SPAC) and announced our intention to seek a NASDAQ listing of 4D pharma American Depositary Shares (ADSs). After the period end, on 22 March 2021, the merger was completed and the listing of 4D pharma ADSs on NASDAQ became effective under the ticker symbol ‘LBPS’; the associated warrants began trading on NASDAQ on 23 March 2021 under the ticker ‘LBPSW’.
Update on the impact of COVID-19
In 2020, the global COVID-19 pandemic affected almost all aspects of the global economy and the pharmaceutical industry, the Group included. In response to this unexpected and unprecedented event, the Group took the situation very seriously and heeded the advice of the UK, Spanish, Irish and US governments and other authorities, utilising technology effectively to mitigate this unprecedented disruption where possible. To protect the safety of patients, the Group’s staff and the staff of the Company’s collaborators, the Group limited non-essential activity at clinical sites which in turn had an impact on patient recruitment for some studies, resulting in some potential delays to expected clinical readouts.
The likely duration of the disruption caused by COVID-19 still remains uncertain, making it difficult to accurately predict the impact on the Group’s operations and clinical timelines. However, in light of this unprecedented situation the Board of Directors carefully re-evaluated the Group’s strategic priorities and near-to-mid-term objectives and took measures to streamline the business and to prioritise allocation of capital and resources to key programs set to deliver key clinical value drivers for our shareholders.
The Group remains committed to reviewing the rapidly evolving global situation and adapting its strategy and operations accordingly.
Organisational changes, Board and governance
In 2020 4D pharma welcomed decades of biopharma experience to our Board and leadership team, providing invaluable expertise to help guide the Company’s ongoing growth and development.
In April, Prof. Axel Glasmacher was appointed Chairperson from his previous role as Non-Executive Director. We expect Prof. Glasmacher to be able to contribute his experience as an oncology physician, Senior Vice President Global Clinical R&D at Celgene and Board member of the Cancer Drug Development Forum, to guide the clinical strategy of 4D’s LBPs including, but not limited to, lead oncology candidate MRx0518.
In August the Board was pleased to welcome Dr. Katrin Rupalla. Dr Rupalla’s appointment as a Non-Executive Director was ratified in September. Dr. Rupalla is currently Senior Vice President Regulatory Affairs, Medical Documentation and R&D Quality at Lundbeck A/S (CPH: LUN), a CNS specialist biotech, and before this spent several years in senior roles overseeing the global development of blockbuster oncology products at Merck & Co., Roche, Celgene and Bristol-Myers Squibb (BMS).
In addition to expanding our Board of Directors, we have also made important additions to our Executive management team. In April we welcomed Glenn Dourado as our new Chief Business Officer, bringing a wealth of expertise in biopharma business development and strategy, with extensive experience particularly with NASDAQ-listed biotechs and in the field of oncology, expanding both our Business Development activities and also our US footprint.
After the period end, in March 2021, we further expanded our Board and management team, appointing John Beck as Chief Financial Officer and Paul Maier as Non-Executive Director; Mr Maier was also appointed Chair of 4D’s Audit and Risk Committee and will serve as the Company’s ‘audit committee financial expert’ under QCA, SEC and NASDAQ rules. Mr. Beck brings over 30 years of experience in financial and biopharmaceutical industry management experience. This includes three previous positions as Chief Financial Officer of publicly traded life sciences companies where he achieved notable results in areas including finance, business and corporate development, strategy, and commercialisation.
Mr. Maier has over 25 years of investor and public relations, operational, regulatory, and finance expertise in the healthcare industry. Mr. Maier was previously the Chief Financial Officer of Sequenom Inc., where he was responsible for raising over
The Board is committed to maintaining high standards of governance, both at Board level and operationally throughout the business.
Group statement of total comprehensive income
For the year ended 31 December 2020
| 31 December | 31 December | |||||||||||
| 2020 | 2019 | |||||||||||
| Notes | ||||||||||||
| Revenue | 534 | 211 | ||||||||||
| Research and development costs | (22,041 | ) | (26,512 | ) | ||||||||
| Administrative expenses | (9,079 | ) | (4,359 | ) | ||||||||
| Foreign currency gains / (losses) | 363 | (1,006 | ) | |||||||||
| Other income | 45 | 34 | ||||||||||
| Operating loss before non-recurring items | (30,178 | ) | (31,632 | ) | ||||||||
| Non-recurring items | — | 2,659 | ||||||||||
| Operating loss after non-recurring items | (30,178 | ) | (28,973 | ) | ||||||||
| Finance income | 5 | 61 | ||||||||||
| Finance expense | (173 | ) | (514 | ) | ||||||||
| Loss before taxation | (30,346 | ) | (29,426 | ) | ||||||||
| Taxation | 3 | 4,383 | 5,360 | |||||||||
| Loss for the year | (25,963 | ) | (24,066 | ) | ||||||||
| Other comprehensive income: | ||||||||||||
| Exchange differences on translating foreign operations | 110 | 379 | ||||||||||
| Loss for the year and total comprehensive income for the year | (25,853 | ) | (23,687 | ) | ||||||||
| Loss per share | ||||||||||||
| Basic and diluted for the year | 4 | (22.80 | )p | (36.75 | )p | |||||||
The basic and diluted loss per share are the same as the effect of share options is anti-dilutive.
Group statement of financial position
At 31 December 2020
| At | At | |||||||||||
| 31 December | 31 December | |||||||||||
| 2020 | 2019 | |||||||||||
| Notes | ||||||||||||
| Assets | ||||||||||||
| Non-current assets | ||||||||||||
| Property, plant and equipment | ||||||||||||
| - Owned assets | 3,659 | 4,196 | ||||||||||
| - Right-of-use assets | 835 | 964 | ||||||||||
| Intangible assets | 14,025 | 13,988 | ||||||||||
| Taxation receivables | 177 | 188 | ||||||||||
| 18,696 | 19,336 | |||||||||||
| Current assets | ||||||||||||
| Inventories | 291 | 198 | ||||||||||
| Trade and other receivables | 3,223 | 1,118 | ||||||||||
| Taxation receivables | 4,436 | 6,122 | ||||||||||
| Cash and cash equivalents | 8,775 | 3,836 | ||||||||||
| 16,725 | 11,274 | |||||||||||
| Total assets | 35,421 | 30,610 | ||||||||||
| Liabilities | ||||||||||||
| Current liabilities | ||||||||||||
| Trade and other payables | 6,379 | 6,192 | ||||||||||
| Lease liabilities | 73 | 68 | ||||||||||
| 6,452 | 6,260 | |||||||||||
| Non-current liabilities | ||||||||||||
| Lease liabilities | 986 | 1,043 | ||||||||||
| Deferred tax | 3 | 13 | 964 | |||||||||
| 999 | 2,007 | |||||||||||
| Total liabilities | 7,451 | 8,267 | ||||||||||
| Net assets | 27,970 | 22,343 | ||||||||||
| Capital and reserves | ||||||||||||
| Share capital | 5 | 329 | 164 | |||||||||
| Share premium account | 5 | 136,278 | 108,296 | |||||||||
| Merger reserve | 958 | 958 | ||||||||||
| Translation reserve | 555 | 446 | ||||||||||
| Other reserve | (864 | ) | (864 | ) | ||||||||
| Share-based payments reserve | 3,497 | 367 | ||||||||||
| Retained earnings | (112,783 | ) | (87,024 | ) | ||||||||
| Total equity | 27,970 | 22,343 | ||||||||||
Group statement of changes in equity
For the year ended 31 December 2020
| Share-based | ||||||||||||||||||||||||||||||||
| Share | Share | Merger | Translation | Other | payment | Retained | Total | |||||||||||||||||||||||||
| capital | premium | reserve | reserve | reserve | reserve | earnings | equity | |||||||||||||||||||||||||
| At 1 January 2019 | 164 | 108,296 | 958 | 67 | (864 | ) | 708 | (63,566 | ) | 45,763 | ||||||||||||||||||||||
| Issue of share capital (net of expenses) | — | — | — | — | — | — | — | — | ||||||||||||||||||||||||
| Total transactions with owners recognised in equity for the year | — | — | — | — | — | — | — | — | ||||||||||||||||||||||||
| Loss and total comprehensive income for the year | — | — | — | 379 | — | — | (24,066 | ) | (23,687 | ) | ||||||||||||||||||||||
| Lapsed options | — | — | — | — | — | (608 | ) | 608 | — | |||||||||||||||||||||||
| Issue of share-based compensation | — | — | — | — | — | 267 | — | 267 | ||||||||||||||||||||||||
| At 31 December 2019 | 164 | 108,296 | 958 | 446 | (864 | ) | 367 | (87,024 | ) | 22,343 | ||||||||||||||||||||||
| Issue of share capital (net of expenses) | 165 | 27,906 | — | — | — | — | — | 28,071 | ||||||||||||||||||||||||
| Issue of Warrants (net of expenses) | — | — | — | — | — | 3,110 | — | 3,110 | ||||||||||||||||||||||||
| Exercise of Warrants | — | 76 | — | — | — | (11 | ) | — | 65 | |||||||||||||||||||||||
| Total transactions with owners recognised in equity for the year | 165 | 27,982 | — | — | — | 3,099 | — | 31,246 | ||||||||||||||||||||||||
| Loss and total comprehensive income for the year | — | — | — | 109 | — | — | (25,963 | ) | (25,854 | ) | ||||||||||||||||||||||
| Lapsed options | — | — | — | — | — | (204 | ) | 204 | — | |||||||||||||||||||||||
| Issue of share-based compensation | — | — | — | — | — | 235 | — | 235 | ||||||||||||||||||||||||
| At 31 December 2020 | 329 | 136,278 | 958 | 555 | (864 | ) | 3,497 | (112,783 | ) | 27,970 | ||||||||||||||||||||||
Group cash flow statement
For the year ended 31 December 2020
| Year to | Year to | |||||||||||
| 31 December | 31 December | |||||||||||
| 2020 | 2019 | |||||||||||
| Notes | ||||||||||||
| Loss after taxation | (25,963 | ) | (24,066 | ) | ||||||||
| Adjustments for: | ||||||||||||
| Depreciation of property, plant and equipment | 1,003 | 1,065 | ||||||||||
| Amortisation of intangible assets | 203 | 216 | ||||||||||
| Profit on disposal of property, plant and equipment | — | (17 | ) | |||||||||
| Loss on disposal of intangible assets | — | 29 | ||||||||||
| Lease liabilities included in the Income statement | 135 | 159 | ||||||||||
| Finance income | (5 | ) | (61 | ) | ||||||||
| Finance expense | 173 | 514 | ||||||||||
| Release of contingent consideration | — | (2,659 | ) | |||||||||
| Share-based compensation | 3,334 | 267 | ||||||||||
| Cash flows from operations before movements in working capital | (21,120 | ) | (24,553 | ) | ||||||||
| Changes in working capital: | ||||||||||||
| (Increase)/decrease in inventories | (93 | ) | 92 | |||||||||
| (Increase)/decrease in trade and other receivables | (2,105 | ) | 130 | |||||||||
| Decrease/(increase) in taxation receivables | 1,697 | (780 | ) | |||||||||
| (Decrease)/increase in trade and other payables | (1,052 | ) | 3,555 | |||||||||
| Cash outflow from operating activities | (22,673 | ) | (21,556 | ) | ||||||||
| Cash flows from investing activities | ||||||||||||
| Purchases of property, plant and equipment | (163 | ) | (538 | ) | ||||||||
| Purchase of software and other intangibles | (15 | ) | (57 | ) | ||||||||
| Cash received on disposal of assets | — | 43 | ||||||||||
| Monies drawn from deposit | — | 10,174 | ||||||||||
| Net cash (outflow)/inflow from investing activities | (178 | ) | 9,622 | |||||||||
| Cash flows from financing activities | ||||||||||||
| Proceeds from issues of ordinary share capital | 5 | 29,740 | — | |||||||||
| Expenses on issue of shares | 5 | (1,594 | ) | — | ||||||||
| Lease liability payments | (188 | ) | (197 | ) | ||||||||
| Interest received | 5 | 94 | ||||||||||
| Interest paid | (173 | ) | (180 | ) | ||||||||
| Net cash inflow/(outflow) from financing activities | 27,790 | (283 | ) | |||||||||
| Increase/(decrease) in cash and cash equivalents | 4,939 | (12,217 | ) | |||||||||
| Cash and cash equivalents at the start of the year | 3,836 | 16,053 | ||||||||||
| Cash and cash equivalents at the end of the year | 8,775 | 3,836 | ||||||||||
Notes
For the year ended 31 December 2020
1. Basis of preparation
The financial information set out herein does not constitute statutory accounts as defined in Section 434 of the Companies Act 2006. The financial information for the year ended 31 December 2020 has been extracted from the Company’s audited financial statements which were approved by the Board of Directors on 31 March 2021 and which, if adopted by the members at the Annual General Meeting, will be delivered to the Registrar of Companies for England and Wales.
The financial information for the year ended 31 December 2019 has been extracted from the Company’s audited financial statements which were approved by the Board of Directors on 22 May 2020 and which drew attention to the material uncertainty over the going concern basis of preparation but received an unqualified audit opinion, did not contain a statement under section 498(2) or (3) of the Companies Act 2006 and have been delivered to the Registrar of Companies.The information in this preliminary statement has been extracted from the audited financial statements for the year ended 31 December 2020 and as such, does not contain all the information required to be disclosed in the financial statements prepared in accordance with the International Financial Reporting Standards as adopted by the European Union (‘IFRS’).
The Company is a public limited company incorporated and domiciled in England & Wales and whose shares are quoted on AIM, a market operated by The London Stock Exchange and through American Depository Shares (ADS’s) listed on NASDAQ . The Company is incorporated in England and Wales. The registered office is 9 Bond Court, Leeds LS1 2JZ.
2. Going concern
The Group and parent company are subject to a number of risks similar to those of other development stage pharmaceutical companies. These risks include, amongst others, generation of revenues in due course from the development portfolio and risks associated with research, development and obtaining regulatory approvals of its products. Ultimately, the attainment of profitable operations is dependent on future uncertain events which include obtaining adequate financing to fulfil the Group’s commercial and development activities and generating a level of revenue to support the Group’s cost structure.
The Directors have prepared detailed financial forecasts and cash flows looking beyond twelve months from the date of the approval of these financial statements. In developing these forecasts, the Directors have made assumptions based upon their view of the current and future economic conditions that are expected to prevail over the forecast period. Shortly after the year-end the Company completed the Merger with Longevity Acquisition Corporation (Longevity) through the issue of new ordinary shares. On completion cash in hand for Longevity was
3. Taxation
The tax credit is made up as follows:
| Year to | Year to | |||||||
| 31 December | 31 December | |||||||
| 2020 | 2019 | |||||||
| Current income tax | ||||||||
| Total current income tax | (3,473 | ) | (5,351 | ) | ||||
| Adjustment in respect of prior years | 42 | (9 | ) | |||||
| Total income tax credit recognised in the year | (3,431 | ) | (5,360 | ) | ||||
| Current deferred tax | ||||||||
| Previously recognised deferred tax gains offset against losses | (940 | ) | — | |||||
| Current year charge | (12 | ) | — | |||||
| Total deferred tax | (952 | ) | — | |||||
| Total income tax credit recognised in the year | (4,383 | ) | (5,360 | ) | ||||
The enacted UK corporation tax rate of
At 31 December 2020, the Group had tax losses available for carry forward of approximately
Group management considers that there is insufficient evidence of future taxable income, taxable temporary differences and feasible tax-planning strategies to utilise all of the cumulative losses and therefore it is not considered certain that the deferred tax assets will be realised in full. If future income differs from current projections, this could significantly impact the tax charge or benefit in future years.
4. Loss per share
(a) Basic and diluted
| Year to | Year to | |||||||
| 31 December | 31 December | |||||||
| 2020 | 2019 | |||||||
| Loss for the year attributable to equity shareholders | (25,963 | ) | (24,066 | ) | ||||
| Weighted average number of shares | ||||||||
| Ordinary shares in issue | 113,851,960 | 65,493,842 | ||||||
| Basic loss per share (pence) | (22.80 | )p | (36.75 | )p | ||||
The basic and diluted loss per share are the same as the effect of share options and warrants is anti-dilutive.
(b) Adjusted
Adjusted loss per share is calculated after adjusting for the effect of non-recurring income and expenses in relation to the reassessment of the contingent liability.
Reconciliation of adjusted loss after tax:
| Year to | Year to | |||||||
| 31 December | 31 December | |||||||
| 2020 | 2019 | |||||||
| Reported loss after tax | (25,963 | ) | (24,066 | ) | ||||
| Non-recurring income | — | (2,659 | ) | |||||
| Adjusted loss after tax | (25,963 | ) | (26,725 | ) | ||||
| Adjusted basic loss per share (pence) | (22.80 | )p | (40.81 | )p | ||||
5. Share capital
| Ordinary | Share | Share | ||||||||||||||
| shares | capital | premium | Total | |||||||||||||
| Group and Company | Number | |||||||||||||||
| Allotted, called up and fully paid ordinary shares of 0.25p | ||||||||||||||||
| Ordinary shares as at 1 January 2019 & 31 December 2019 | 65,493,842 | 164 | 108,296 | 108,460 | ||||||||||||
| Placing and subscription 18 February 2020 | 44,000,000 | 110 | 21,890 | 22,000 | ||||||||||||
| Expenses of placing and subscription on 18 February 2020 | — | — | (1,065 | ) | (1,065 | ) | ||||||||||
| Warrants exercised (issued 18 February 2020) | 75,693 | — | 76 | 76 | ||||||||||||
| Placing and subscription 13 July 2020 | 21,898,400 | 55 | 7,610 | 7,665 | ||||||||||||
| Expenses of placing and subscription on 13 July 2020 | — | — | (529 | ) | (529 | ) | ||||||||||
| Ordinary shares as at 31 December 2020 | 131,467,935 | 329 | 136,334 | 136,663 | ||||||||||||
The balances classified as share capital and share premium include the total net proceeds (nominal value and share premium respectively) on issue of the Company’s equity share capital. The entire share capital consists of 0.25 pence ordinary shares.
Each ordinary 0.25 pence share is entitled to:
| ● | one vote in any circumstances; | |
| ● | Pari passu to dividend payments or any other distribution; and, | |
| ● | Pari passu to participate in a distribution arising from a winding up of the Company. |
The Company raised
The Company raised
6. Related party transactions
Interest in Shares and Warrants
During the year the Company undertook two capital raises through the issue of shares and warrants. Details of the Directors’ participation in these raises and other share acquisitions is as follows:
| Executive Directors | Duncan Peyton CEO | Dr Alex Stevenson CSO | ||||||||||||||||||||||
| Shares and Warrants | Number of shares | Number of warrants | £ | Number of shares | Number of warrants | £ | ||||||||||||||||||
| At 1 January 2020 | 6,455,075 | — | 6,413,136 | — | ||||||||||||||||||||
| Subscription on 18 February 2020 at | 1,333,332 | 666,666 | 666,666 | 1,333,332 | 666,666 | 666,666 | ||||||||||||||||||
| Total at 18 February 2020 | 7,788,407 | 666,666 | 666,666 | 7,746,468 | 666,666 | 666,666 | ||||||||||||||||||
| Subscription on 13 July 2020 at | 571,428 | — | 200,000 | 571,428 | — | 200,000 | ||||||||||||||||||
| Total at 13 July 2020 | 8,359,835 | 666,666 | 866,666 | 8,317,896 | 666,666 | 866,666 | ||||||||||||||||||
| Percentage of enlarged share capital at 13 July 2020 | 6.36 | % | 6.33 | % | ||||||||||||||||||||
| Non-Executive Directors | David Norwood* NED | Prof. Axel Glasmacher NED | ||||||||||||||||||||||
| Shares and Warrants | Number of shares | Number of warrants | £ | Number of shares | Number of warrants | £ | ||||||||||||||||||
| At 1 January 2020 | 7,123,725 | — | — | — | ||||||||||||||||||||
| Subscription on 18 February 2020 at | 1,333,336 | 666,668 | 666,668 | — | — | — | ||||||||||||||||||
| Total at 18 February 2020 | 8,457,061 | 666,668 | 666,668 | — | — | — | ||||||||||||||||||
| Market based purchase 17 March 2020 at | 100,000 | — | 28,000 | — | — | — | ||||||||||||||||||
| Subscription on 13 July 2020 at | 285,714 | — | 100,000 | 30,000 | — | 10,500 | ||||||||||||||||||
| Total at 13 July 2020 | 8,842,775 | 666,668 | 794,668 | 30,000 | — | 10,500 | ||||||||||||||||||
| Percentage of enlarged share capital at 13 July 2020 | 6.73 | % | 0.02 | % | ||||||||||||||||||||
| * | David Norwood resigned as a Director on 30 September 2020. As his shareholding was not sufficient for him to qualify as a substantial shareholder, transactions after this date have been excluded. |
No warrants had been exercised by the existing Directors at 31 December 2020.
Further details of shares issued and proceeds from their issue can be found in note 21 to the full accounts.
Merger with Longevity Acquisition Corporation
On 22 October 2020 the Company announced its intention to merge with Longevity Acquisition Corporation (Longevity), a Special Purpose Acquisition Company, and its intention to seek a NASDAQ listing.
To secure the merger a backstop agreement was put in place involving certain of the Directors and significant shareholders (the “Backstop Investors”). The details of the agreement at 31 December 2020 were as follows:
Backstop Arrangements and Related Party Transactions
The current Longevity shareholders have the right to redeem their shareholding in Longevity, even if the requisite majority of Longevity shareholders approve the merger.
The Backstop Investors have committed to subscribe for Longevity shares prior to completion so as to raise up to
The Backstop arrangements also provide that, subject to certain conditions, 4D may be required to file, within thirty days after completion, a registration statement under the US Securities Act registering the resale of the 4D ordinary shares received by the Backstop Investors pursuant to the merger and the Backstop arrangements. The Backstop Investors have agreed to loan Longevity US
Related Party Transactions
The participation by Duncan Peyton (in the amount of
The 4D Independent Directors, having consulted with the Company’s nominated adviser, N+1 Singer, consider that the terms of the related party transactions are fair and reasonable insofar as Shareholders are concerned. In providing their advice to the 4D Independent Directors, N+1 Singer have taken into account the commercial assessments of the 4D Independent Directors.
Lock-up Agreements
Duncan Peyton and Alex Stevenson, being the Chief Executive Officer and Chief Scientific Officer respectively, will enter into lock-up agreements at completion. Under the terms of the lock-up agreement, each of Mr Peyton and Dr Stevenson will agree that, subject to certain limited exceptions, they will not sell any consideration shares due to them under the terms of the merger for a period of twelve months.
7. Subsequent events
Merger with Longevity Acquisition Corporation
On 18 March 2021 (the “Closing Date”), the transaction (the “Closing”) contemplated by the previously announced Merger Agreement and BVI Plan of Merger (the “Merger”), dated as of 21 October 2020 (the “Merger Agreement”), by and among Longevity Acquisition Company (“Longevity”), 4D Pharma plc (“4D Pharma”), and Dolphin Merger Sub Limited, a British Virgin Islands company and a wholly-owned subsidiary of 4D Pharma (the “Merger Sub”) was approved and the transaction was completed on 22 March 2021. The Merger Sub is the surviving entity (the “Surviving Corporation”). As a result of the Merger, each Longevity share issued and outstanding immediately prior to the completion of the Merger was converted into the right to receive 7.5315 ordinary shares of 4D Pharma payable in 4D Pharma ADSs (“American Depositary Shares”) at a rate equal to one 4D Pharma ADS for every eight 4D Pharma ordinary shares. 4D Pharma issued no fractional 4D Pharma Shares or 4D Pharma ADSs in the Merger. Each warrant to purchase Longevity Shares and right to receive Longevity Shares that was outstanding immediately prior to the Closing was assumed by 4D Pharma and automatically converted into a warrant to purchase ordinary shares of 4D Pharma and a right to receive ordinary shares of 4D Pharma, payable in 4D Pharma ADSs, respectively.
In connection with the Closing, certain holders of Longevity common shares exercised their right to redeem those shares in accordance with the Company’s organisational documents, as amended, for cash at a price of approximately
At the Closing, 4D Pharma entered into a Lock-up Agreement with the Sponsor and certain shareholders of 4D. Pursuant to the Lock-Up Agreement, each holder agreed that, subject to certain exceptions, during the period ending twelve months after the Closing, it will not (i) lend, offer, pledge, hypothecate, encumber, donate, assign, sell, contract to sell, sell any option or contract to purchase, purchase any option or contract to sell, grant any option, right or warrant to purchase, or otherwise transfer or dispose of, directly or indirectly, any shares received as consideration in the Merger (the “Restricted Securities”), (ii) enter into any swap, short sale, hedge or other arrangement that transfers to another, in whole or in part, any of the economic consequences of ownership of the Restricted Securities, or (iii) publicly disclose the intention to effect any transaction specified in clause (i) or (ii), or (iv) make any demand for or exercise any right with respect to the registration of any Longevity Shares.
As Longevity has no ongoing trade or business, the Merger does not constitute a business combination under IFRS 3. As such the transaction will be treated as a financing through the issue of ordinary shares in 4D Pharma. At Closing, Longevity had approximately
NASDAQ Listing
On 22 March 2021, with the completion of the Longevity transaction, the Company completed its NASDAQ Global Market listing using American Depositary Shares (ADSs) under the ticker ‘LBPS’ and the following day the warrants began trading under the ‘LBPSW’ ticker. Ordinary shares can be converted at any time to ADSs at a ratio of eight ordinary shares for one ADS. J.P Morgan Chase bank, N.A. is acting as depositary bank for the ADSs and the Company’s ordinary shares will continue to be admitted to trading on AIM under the ticker ‘DDDD’
Private Placement Financing
On 17 March 2021, the Company announced that it had entered into securities purchase agreements with certain US and UK institutional and accredited investors to raise approximately
Overdraft Facility
In March 2021 4D Pharma Leon S.L.U. agreed a
8. Report and accounts
A copy of the Annual Report and Accounts will be sent to all shareholders with notice of the Annual General Meeting, and will be made available on the Company’s website, www.4dpharmaplc.com, by 14 April 2021.
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