Welcome to our dedicated page for Karyopharm Therapeutics news (Ticker: KPTI), a resource for investors and traders seeking the latest updates and insights on Karyopharm Therapeutics stock.
Karyopharm Therapeutics Inc. (Nasdaq: KPTI) is a commercial-stage pharmaceutical company focused on pioneering novel cancer therapies. The company specializes in the discovery, development, and commercialization of drugs targeting nuclear export proteins for the treatment of cancer and other significant diseases. Its flagship product, XPOVIO® (selinexor), is a first-in-class, oral exportin 1 (XPO1) inhibitor and is approved in the U.S. for multiple oncology indications. These include combination therapies with Velcade® (bortezomib) and dexamethasone for multiple myeloma, as well as treatments for adult patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL).
Recent achievements highlight the company's commitment to advancing its late-stage clinical pipeline. Notably, Karyopharm has been at the forefront in evaluating selinexor's efficacy in combination therapies for multiple myeloma, endometrial cancer, and myelofibrosis. The company recently reported long-term follow-up data from a Phase 1/3 study on selinexor in combination with ruxolitinib in myelofibrosis patients, showing promising results in spleen volume and symptom reduction.
Financially, Karyopharm reported total revenue of $33.7 million for Q4 2023, with a full-year revenue of $146.0 million. Despite a competitive market, the company managed to maintain steady growth and focused resources on its high-potential pipeline. With a cash position of $192.4 million as of December 31, 2023, Karyopharm is well-positioned to continue its innovative research and development efforts.
Karyopharm's collaborations with global partners, including Antengene, Menarini, Neopharm, and FORUS, have extended the reach of XPOVIO to various international markets such as Europe, China, South Korea, and Israel. This international expansion underscores the global demand for innovative cancer therapies.
For more information, please visit www.karyopharm.com.
Karyopharm Therapeutics (Nasdaq: KPTI) announced that its senior management will participate in the Jefferies Global Healthcare Conference on June 5, 2024, in New York. The event includes a fireside chat at 1:00 p.m. ET. A live webcast and slides will be available on the company's website under the 'Events & Presentations' section and for replay afterward.
Karyopharm Therapeutics Inc. (Nasdaq: KPTI) will participate in the 2024 RBC Capital Markets Global Healthcare Conference with a fireside chat on May 15. The live webcast can be accessed on the company's website.
Karyopharm Therapeutics Inc. announced significant refinancing transactions, extending the vast majority of its debt maturities to 2028 and 2029. The company exchanged $148.0 million of existing convertible notes due in 2025 for $111.0 million of new convertible notes due in 2029 and warrants. Additionally, a new $100.0 million senior secured term loan was issued, repaying principal portions and amending a royalty agreement with HealthCare Royalty. These transactions fortify the company's balance sheet and enhance its ability to unlock the potential of selinexor.
Karyopharm Therapeutics Inc. reported first-quarter 2024 financial results, highlighting revenue of $33.1 million, with $26.0 million from U.S. XPOVIO net product revenue. The company reaffirmed its full-year revenue guidance of $140.0 million to $160.0 million, including U.S. XPOVIO net product revenue guidance of $100.0 million to $120.0 million. Karyopharm made significant refinancing transactions and amended a royalty agreement to extend debt maturities into 2028 and 2029, strengthening its position for future growth. The company also presented data from the Phase 3 SIENDO trial of Selinexor maintenance treatment in endometrial cancer patients at the 2024 ASCO Annual Meeting.
Karyopharm Therapeutics Inc. (Nasdaq: KPTI) will report its first quarter 2024 financial results on May 8, 2024. The management team will host a conference call and audio webcast to discuss the financial results and other updates. Investors can access the call and webcast through the company's website.
Karyopharm Therapeutics Inc. granted 72,700 restricted stock units (RSUs) to five new employees on April 30, 2024, under the 2022 Inducement Stock Incentive Plan. These RSUs will vest over three years, with 33 1/3% vesting annually. The awards are subject to continued service and can be fully exercisable in case of a 'change in control event' within the first year.
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