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Chinook Therapeutics Announces Upcoming Encore Presentations at ISN World Congress of Nephrology 2022

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Chinook Therapeutics (NASDAQ: KDNY) will present several abstracts at the ISN World Congress of Nephrology 2022 from February 24 to 27, 2022. Key presentations include data from:

  • Atrasentan: The ALIGN Study (Phase 3 on IgA Nephropathy)
  • Atrasentan: The AFFINITY Study (Proteinuric Glomerular Diseases)
  • BION-1301: Phase 1/2 Trial Results on IgA Nephropathy
  • BION-1301: ADU-CL-19 Trial on Safety and Pharmacodynamics

Chinook focuses on precision treatments for severe chronic kidney diseases.

Positive
  • Presentations at a prominent conference could enhance visibility and credibility.
  • Focus on IgA nephropathy and proteinuric glomerular diseases aligns with significant unmet medical needs.
  • Participation in ISN World Congress may attract potential collaborations or investments.
Negative
  • None.

SEATTLE, Feb. 18, 2022 (GLOBE NEWSWIRE) -- Chinook Therapeutics, Inc. (NASDAQ: KDNY), a biopharmaceutical company focused on the discovery, development and commercialization of precision medicines for kidney diseases, today announced upcoming presentations at the ISN World Congress of Nephrology 2022 from February 24 – 27, 2022.

The following abstracts will be presented as poster presentations at the ISN World Congress of Nephrology 2022:

Atrasentan   
Abstract WCN22-0484  A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of Atrasentan in Patients with IgA Nephropathy (The ALIGN Study)
Author:  Hiddo J. L. Heerspink, PhD, PharmD, University Medical Center Groningen, Groningen, Netherlands
    
Abstract WCN22-0480  Atrasentan in Patients with Proteinuric Glomerular Diseases (The AFFINITY Study)
Author:  Anjay Rastogi, MD, PhD, UCLA David Geffen School of Medicine, Los Angeles, CA
    
BION-1301   
Abstract WCN22-0485 
  Pharmacodynamic and Clinical Responses to BION-1301 in Patients with IgA Nephropathy: Initial Results of a Phase 1/2 Trial
Author:  Jonathan Barratt, MChB, PhD, FRCP, University of Leicester, Leicester, UK
    
Abstract WCN22-0483  ADU-CL-19: A Phase 1/2, Multicenter Trial to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of BION-1301 in Healthy Volunteers and Adults With IgA Nephropathy
Author:  Jonathan Barratt, MChB, PhD, FRCP, University of Leicester, Leicester, UK
    
For more information on these and other abstracts, please visit the ISN World Congress of Nephrology 2022 website.


About Chinook Therapeutics, Inc.

Chinook Therapeutics, Inc. is a clinical-stage biopharmaceutical company developing precision medicines for kidney diseases. Chinook’s product candidates are being investigated in rare, severe chronic kidney disorders with opportunities for well-defined clinical pathways. Chinook’s lead program is atrasentan, a phase 3 endothelin receptor antagonist for the treatment of IgA nephropathy and other proteinuric glomerular diseases. BION-1301, an anti-APRIL monoclonal antibody is being evaluated in a phase 1/2 trial for IgA nephropathy. In addition, Chinook is advancing CHK-336, an oral small molecule LDHA inhibitor for the treatment of primary hyperoxaluria, as well as research programs for other rare, severe chronic kidney diseases. Chinook is building its pipeline by leveraging insights in kidney single cell RNA sequencing, human-derived organoids and new translational models, to discover and develop therapeutics with differentiating mechanisms of action against key kidney disease pathways. To learn more, visit www.chinooktx.com.


FAQ

What presentations will Chinook Therapeutics showcase at ISN World Congress of Nephrology 2022?

Chinook Therapeutics will present several abstracts focused on Atrasentan and BION-1301, including Phase 3 and Phase 1/2 trial data related to IgA nephropathy and proteinuric glomerular diseases.

When is the ISN World Congress of Nephrology 2022?

The ISN World Congress of Nephrology 2022 will take place from February 24 to 27, 2022.

What is Atrasentan being studied for?

Atrasentan is being studied for its effectiveness in treating IgA nephropathy and other proteinuric glomerular diseases.

What is BION-1301 aimed at?

BION-1301 is aimed at treating IgA nephropathy and is currently being evaluated in Phase 1/2 trials.

Chinook Therapeutics, Inc.

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