Jaguar Health Family Company Napo Therapeutics Named “Best Pharmaceuticals Innovator of the Year - Europe”
Napo Therapeutics, a Jaguar Health family company, has been named 'Best Pharmaceuticals Innovator of the Year - Europe' by The European business publication. The company is advancing crofelemer, a novel oral plant-based prescription drug, for rare diseases in Europe.
The company is supporting proof-of-concept studies for microvillus inclusion disease (MVID) and short bowel syndrome (SBS) with results expected by end of 2024 and throughout 2025. Phase 2 trials for both conditions are planned to start before end of 2024. These studies could support early patient access to crofelemer in specific EU countries.
Napo Therapeutics, un'azienda del gruppo Jaguar Health, è stata nominata 'Miglior Innovatore Farmaceutico dell'Anno - Europa' dalla pubblicazione business europea. L'azienda sta sviluppando crofelemer, un nuovo farmaco orale a base vegetale, per malattie rare in Europa.
L'azienda sta supportando studi di prova di concetto per la malattia da inclusione dei microvilli (MVID) e la sindrome dell'intestino corto (SBS), con risultati attesi entro la fine del 2024 e per tutto il 2025. I trial di fase 2 per entrambe le condizioni sono previsti per iniziare prima della fine del 2024. Questi studi potrebbero supportare l'accesso anticipato dei pazienti a crofelemer in alcuni paesi specifici dell'UE.
Napo Therapeutics, una empresa de la familia Jaguar Health, ha sido nombrada 'Mejor Innovador Farmacéutico del Año - Europa' por la publicación empresarial europea. La empresa está promoviendo crofelemer, un novedoso medicamento oral de origen vegetal, para enfermedades raras en Europa.
La empresa está apoyando estudios de prueba de concepto para la enfermedad de inclusión de microvellosidades (MVID) y el síndrome del intestino corto (SBS), con resultados esperados para finales de 2024 y a lo largo de 2025. Los ensayos de fase 2 para ambas condiciones están programados para comenzar antes de finales de 2024. Estos estudios podrían facilitar el acceso temprano de los pacientes a crofelemer en países específicos de la UE.
Napo Therapeutics는 Jaguar Health 패밀리 회사로서 유럽 비즈니스 출판사로부터 '올해의 최고의 제약 혁신 기업 - 유럽'으로 선정되었습니다. 이 회사는 유럽의 희귀 질병을 위한 새로운 식물 기반 경구 처방약 크로페레머를 개발하고 있습니다.
회사는 미세융모 포괄증 (MVID) 및 짧은 장 증후군 (SBS)에 대한 개념 증명 연구를 지원하고 있으며, 결과는 2024년 말과 2025년 내내 기대하고 있습니다. 두 질환에 대한 2상 임상 시험이 2024년 말 이전에 시작될 예정입니다. 이러한 연구는 특정 EU 국가에서 환자들이 조기에 크로페레머에 접근할 수 있도록 지원할 수 있습니다.
Napo Therapeutics, une entreprise de la famille Jaguar Health, a été nommée 'Meilleur Innovateur Pharma de l'Année - Europe' par une publication européenne spécialisée dans les affaires. L'entreprise développe crofelemer, un nouveau médicament oral à base de plantes, pour des maladies rares en Europe.
L'entreprise soutient des études de preuve de concept pour la maladie d'inclusion des microvillosités (MVID) et le syndrome de l'intestin court (SBS), avec des résultats attendus d'ici fin 2024 et tout au long de 2025. Des essais de phase 2 pour ces deux conditions sont prévus pour commencer avant la fin de 2024. Ces études pourraient soutenir un accès précoce des patients à crofelemer dans des pays spécifiques de l'UE.
Napo Therapeutics, ein Unternehmen der Jaguar Health Familie, wurde von der europäischen Fachpublikation als 'Bester pharmazeutischer Innovator des Jahres - Europa' ausgezeichnet. Das Unternehmen entwickelt Crofelemer, ein neuartiges pflanzliches Rezeptmedikament für seltene Krankheiten in Europa.
Das Unternehmen unterstützt Machbarkeitsstudien für Mikrovillusinclusionskrankheit (MVID) und kurzes Darm-Syndrom (SBS), wobei Ergebnisse bis Ende 2024 und im gesamten Jahr 2025 erwartet werden. Phase-2-Studien für beide Erkrankungen sind geplant, vor Ende 2024 zu beginnen. Diese Studien könnten den frühen Zugang von Patienten zu Crofelemer in spezifischen EU-Ländern unterstützen.
- Supporting proof-of-concept studies for two rare disease indications (MVID and SBS)
- Phase 2 trials for both MVID and SBS planned to initiate by end of 2024
- Potential early patient access to crofelemer in EU countries based on clinical data
- None.
Established in Milan, Italy in 2021, Napo Therapeutics is focused on expanding access to crofelemer, Jaguar's novel oral plant-based prescription drug, in Europe for orphan and/or rare diseases
SAN FRANCISCO, CA / ACCESSWIRE / November 19, 2024 / Jaguar Health, Inc. (NASDAQ:JAGX) (Jaguar) today announced that Jaguar family company Napo Therapeutics has been named "Best Pharmaceuticals Innovator of the Year - Europe" by The European, a quarterly business publication published by CP Media Global Ltd in London.
"We are very honored to receive this award," said Massimo Radaelli, PhD, Chief Executive Officer of Napo Therapeutics and President of Jaguar International, "as we continue to be laser-focused on our mission of expanding access to crofelemer in Europe for orphan and rare diseases."
In participation with Jaguar and Jaguar family company Napo Pharmaceuticals, Napo Therapeutics is supporting investigator-initiated proof-of-concept (POC) studies of crofelemer for the rare disease indications of microvillus inclusion disease (MVID) and short bowel syndrome (SBS) with intestinal failure in the US, EU, and Middle East/North Africa regions, with results expected by the end of 2024 and throughout 2025. Additionally, a phase 2 trial of crofelemer in adult SBS patients with intestinal failure is expected to initiate before the end of 2024, as is a phase 2 trial of crofelemer in pediatric MVID patients. In accordance with the guidelines of specific EU countries, published data from clinical investigations in such rare diseases could support early patient access to crofelemer for these debilitating conditions in those countries.
Some SBS patients are subject to intestinal failure, often requiring parenteral nutrition (PN) up to 7 days a week. Intestinal failure is associated with significant morbidity and mortality; and high medical expenses associated with PN. SBS patients with intestinal failure also have severe chronic diarrhea, and the associated sequelae from diarrhea, including significant dehydration, metabolic acidosis or alkalosis and malnutrition, and other secondary symptoms, and these symptoms emerge either early or late, and many times become life-threatening.
MVID, an ultrarare congenital diarrheal disorder, is a severe infantile disease characterized by diarrhea, malabsorption, and acid/base instability, requiring intensive parenteral support for nutritional and fluid management, and there are currently no approved drug treatments.
The European, throughout the last decade, has been celebrating achievement, innovation and excellence through its annual awards program. The aim is to give corporate organizations an insight into various achievements within a range of organizations and reward excellence in the global business community. Covering a broad spectrum of business affairs globally, including Energy, Banking and Finance, Foreign Direct Investment, Sustainability, ESG, Shipping, Aviation, Executive Education, Technology, Lifestyle and Business Travel, The European is intended for decision makers around the world and is available through a global distribution network in EMEA, LATAM, North America and Asia.
About Crofelemer
Crofelemer is a novel, oral plant-based prescription medicine purified from the red bark sap, also referred to as "dragon's blood," of the Croton lechleri tree in the Amazon Rainforest. Napo Pharmaceuticals has established a sustainable harvesting program, under fair trade practices, for crofelemer to ensure a high degree of quality, ecological integrity, and support for indigenous communities.
About the Jaguar Health Family of Companies
Jaguar Health, Inc. (Jaguar) is a commercial stage pharmaceuticals company focused on developing novel proprietary prescription medicines sustainably derived from plants from rainforest areas for people and animals with gastrointestinal distress, specifically associated with overactive bowel, which includes symptoms such as chronic debilitating diarrhea, urgency, bowel incontinence, and cramping pain. Jaguar family company Napo Pharmaceuticals (Napo) focuses on developing and commercializing human prescription pharmaceuticals for essential supportive care and management of neglected gastrointestinal symptoms across multiple complicated disease states. Napo's crofelemer is FDA-approved under the brand name Mytesi® for the symptomatic relief of noninfectious diarrhea in adults with HIV/AIDS on antiretroviral therapy. Jaguar family company Napo Therapeutics is an Italian corporation Jaguar established in Milan, Italy in 2021 focused on expanding crofelemer access in Europe and specifically for orphan and/or rare diseases. Jaguar Animal Health is a Jaguar tradename. Magdalena Biosciences, a joint venture formed by Jaguar and Filament Health Corp. that emerged from Jaguar's Entheogen Therapeutics Initiative (ETI), is focused on developing novel prescription medicines derived from plants for mental health indications.
For more information about:
Jaguar Health, visit https://jaguar.health
Napo Pharmaceuticals, visit www.napopharma.com
Napo Therapeutics, visit napotherapeutics.com
Magdalena Biosciences, visit magdalenabiosciences.com
Visit the Make Cancer Less Shitty patient advocacy program at makecancerlessshitty.com and on Bluesky, X, Facebook & Instagram
Forward-Looking Statements
Certain statements in this press release constitute "forward-looking statements." These include statements regarding Jaguar's expectation that results of investigator-initiated proof-of-concept studies of crofelemer for SBS with intestinal failure and MVID will be available by the end of 2024 and throughout 2025, Jaguar's expectation that a phase 2 trial of crofelemer in adult SBS patients with intestinal failure and a phase 2 trial of crofelemer in pediatric MVID patients will initiate before the end of 2024, and Jaguar's expectation that, in accordance with the guidelines of specific EU countries, published data from such clinical investigations could support early patient access to crofelemer for SBS with intestinal failure or MVID. In some cases, you can identify forward-looking statements by terms such as "may," "will," "should," "expect," "plan," "aim," "anticipate," "could," "intend," "target," "project," "contemplate," "believe," "estimate," "predict," "potential" or "continue" or the negative of these terms or other similar expressions. The forward-looking statements in this release are only predictions. Jaguar has based these forward-looking statements largely on its current expectations and projections about future events. These forward-looking statements speak only as of the date of this release and are subject to several risks, uncertainties, and assumptions, some of which cannot be predicted or quantified and some of which are beyond Jaguar's control. Except as required by applicable law, Jaguar does not plan to publicly update or revise any forward-looking statements contained herein, whether as a result of any new information, future events, changed circumstances or otherwise.
Contact:
hello@jaguar.health
Jaguar-JAGX
SOURCE: Jaguar Health, Inc.
View the original press release on accesswire.com
FAQ
What award did Napo Therapeutics (JAGX) receive in 2024?
What rare diseases is Jaguar Health (JAGX) studying crofelemer for in Europe?
When will JAGX's proof-of-concept study results for MVID and SBS be available?
