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Ipsen Delivers Strong Sales Growth in the First Nine Months of 2022 and Confirms Its Full-year Guidance

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Ipsen (IPSEY) reported robust sales performance for YTD 2022, with total sales reaching €2,208.5m, marking a 15.5% increase year-over-year, and growth of 9.5% at constant exchange rates (CER). Key drivers included Oncology sales rising by 12.9%, Neuroscience by 31.7%, and total sales in Q3 up 16.0%. However, Rare Disease sales decreased by 9.8%, and Somatuline sales suffered a 2.8% decline due to increased competition. Ipsen confirmed its FY 2022 guidance, expecting total-sales growth greater than 7% at CER. The recent acquisition of Epizyme enhances Ipsen’s Oncology portfolio.

Positive
  • Total sales increased by 15.5% YoY, reaching €2,208.5m.
  • Oncology sales grew by 12.9%, significantly contributing to total sales.
  • Neuroscience sales saw a remarkable increase of 31.7%.
  • Q3 total sales surged by 16.0% compared to Q3 2021.
  • Acquisition of Epizyme enhances Oncology capabilities.
Negative
  • Somatuline sales declined by 2.8% due to competitive pressure.
  • Rare Disease segment experienced a 9.8% drop in sales.

PARIS--(BUSINESS WIRE)-- Regulatory News:

Ipsen (Euronext: IPN; ADR: IPSEY), a global specialty-driven biopharmaceutical company, today presents its sales performance for the year to date and the third quarter of 2022.

Sales summary1

 

YTD
2022

YTD
2021

% change

Q3
2022

Q3
2021

% change

€m

€m

Actual

CER2

€m

€m

Actual

CER2

Oncology

1,767.2

1,565.4

12.9%

6.9%

603.1

552.3

9.2%

1.2%

Neuroscience

407.7

309.6

31.7%

25.1%

160.7

103.8

54.8%

43.4%

Rare Disease

33.6

37.3

-9.8%

-12.5%

11.0

11.7

-5.4%

-9.3%

Total Sales

2,208.5

1,912.3

15.5%

9.5%

774.8

667.8

16.0%

7.6%

Highlights

– Total-sales growth in the year to date of 9.5% at CER2, or 15.5% as reported, driven by the growth platforms of Dysport® (botulinum toxin type A), Decapeptyl® (triptorelin), Cabometyx® (cabozantinib) and Onivyde® (irinotecan) increasing by 20.8%2; Somatuline® (lanreotide) sales down by 2.8%2

In the third quarter, total-sales growth of 7.6% at CER2, or 16.0% as reported, boosted by an increase in Dysport sales of 43.3%2, partly offset by a decline in Somatuline sales of 9.8%2

Completion of the definitive merger agreement under which Ipsen acquired Epizyme, expanding Ipsen’s presence in Oncology

– Postponement of the U.S. FDA’s advisory-committee meeting for investigational palovarotene

– Full-year 2022 guidance confirmed, with total-sales growth greater than 7.0% at CER2 and a core operating margin greater than 36.0% of total sales

David Loew, Chief Executive Officer, commented:

“I am proud of Ipsen’s performance so far this year as we continue to drive strong sales results. Our growth platforms have delivered a double-digit sales performance, reflecting improving commercial execution and the strength of our portfolio. These results have outweighed the adverse impact from competitive activity on Somatuline in the U.S. and Europe. Based on the strong sales momentum, we are confirming our guidance for the full year.

I was also delighted by the enhancement of our pipeline, portfolio and organization as a result of the recent acquisition of Epizyme. In the near term, we look forward to a number of milestones for our pipeline, including Phase III data readouts in Oncology. I am pleased with the sustained progress we are making as we continue to maximize our brands, strengthen our pipeline, drive efficiencies and focus on our culture.”

Full-year 2022 guidance

Ipsen has confirmed its financial guidance for FY 20223:

– Total-sales growth greater than 7.0%, at constant exchange rates. Based on the average level of exchange rates in September 2022, an additional favorable impact on total sales of around 6% from currencies is expected

– Core operating margin greater than 36.0% of total sales

Business development

In August 2022, Ipsen and Epizyme, Inc. (Epizyme) announced that they had completed a definitive merger agreement under which Ipsen acquired Epizyme, a fully integrated, commercial-stage biopharmaceutical company developing and delivering transformative therapies against novel epigenetic targets for cancer patients. Sales by Ipsen ofTazverik® (tazemetostat), consolidated from 1 September 2022, have been reflected in this announcement.

Ipsen and Marengo Therapeutics, Inc. (Marengo) also announced in August 2022 a strategic partnership to advance two of Marengo’s preclinical STAR platform-generated candidates into the clinic. The collaboration will leverage Marengo’s proprietary R&D expertise of a novel mechanism of T-cell activation with Ipsen’s global Oncology footprint for clinical development and commercialization.

Palovarotene

In October 2022, the U.S. FDA announced its decision to postpone the planned Endocrinologic and Metabolic Drugs Advisory Committee meeting for investigational palovarotene until a later date to be confirmed; the original advisory-committee meeting was scheduled for 31 October 2022. The FDA informed Ipsen that the postponement related to an FDA request for new information on palovarotene clinical-trial data and did not relate to the safety profile of palovarotene. The Company is currently working to fulfil the request.

Conference call

A conference call and webcast for investors and analysts will begin today at 1.30pm, Paris time. Participants can access the call and its details by registering here; webcast details can be found here. A recording will be available on ipsen.com.

Calendar

Ipsen intends to publish its full-year results on 9 February 2023.

Notes

All financial figures are in € millions (€m). The performance shown in this announcement covers the nine-month period to 30 September 2022 (the year to date or YTD 2022) and the three-month period to 30 September 2022 (the third quarter or Q3 2022), compared to nine-month period to 30 September 2021 (YTD 2021) and the three-month period to 30 September 2021 (Q3 2021) respectively, unless stated otherwise. Commentary is based on the performance in YTD 2022, unless stated otherwise. The performance of Consumer HealthCare, divested in July 2022, has been excluded from all commentary and comparisons to prior performance.

Ipsen

Ipsen is a global, mid-sized biopharmaceutical company focused on transformative medicines in Oncology, Rare Disease and Neuroscience. With Specialty Care sales of €2.6bn in FY 2021, Ipsen sells medicines in over 100 countries. Alongside its external-innovation strategy, the Company’s research and development efforts are focused on its innovative and differentiated technological platforms located in the heart of leading biotechnological and life-science hubs: Paris-Saclay, France; Oxford, U.K.; Cambridge, U.S.; Shanghai, China. Ipsen has around 5,000 colleagues worldwide and is listed in Paris (Euronext: IPN) and in the U.S. through a Sponsored Level I American Depositary Receipt program (ADR: IPSEY). For more information, visit ipsen.com.

Total sales by therapy area and medicine

 

 

YTD
2022

YTD
2021

% change

 

Q3
2022

Q3
2021

% change

 

€m

 

€m

 

Actual

CER4

 

€m

 

€m

 

Actual

CER4

Oncology

 

1,767.2

 

1,565.4

 

12.9%

 

6.9%

 

603.1

 

552.3

 

9.2%

 

1.2%

Somatuline

 

911.9

 

874.4

 

4.3%

 

-2.8%

 

311.9

 

313.0

 

-0.3%

 

-9.8%

Decapeptyl

 

396.0

 

332.6

 

19.1%

 

15.6%

 

131.4

 

110.1

 

19.3%

 

14.9%

Cabometyx

 

327.7

 

258.6

 

26.7%

 

24.1%

 

115.5

 

91.8

 

25.9%

 

21.8%

Onivyde

 

122.0

 

93.0

 

31.1%

 

17.1%

 

38.8

 

35.2

 

10.1%

 

-5.3%

Tazverik

 

2.8

 

0.0

 

n/a5

 

n/a5

 

2.8

 

0.0

 

n/a5

 

n/a5

Other Oncology

 

6.9

 

6.7

 

2.0%

 

1.6%

 

2.6

 

2.2

 

18.1%

 

18.2%

Neuroscience

 

407.7

 

309.6

 

31.7%

 

25.1%

 

160.7

 

103.8

 

54.8%

 

43.4%

Dysport

 

400.3

 

305.3

 

31.1%

 

24.8%

 

158.0

 

102.5

 

54.1%

 

43.3%

Other Neuroscience

 

7.3

 

4.3

 

70.5%

 

49.1%

 

2.7

 

1.3

 

n/a5

 

54.1%

Rare Disease

 

33.6

 

37.3

 

-9.8%

 

-12.5%

 

11.0

 

11.7

 

-5.4%

 

-9.3%

NutropinAq®

 

20.8

 

24.5

 

-15.3%

 

-15.5%

 

6.3

 

7.5

 

-16.1%

 

-16.4%

Increlex®

 

12.8

 

12.8

 

-0.2%

 

-7.4%

 

4.8

 

4.2

 

13.5%

 

3.3%

Total Sales

 

2,208.5

 

1,912.3

 

15.5%

 

9.5%

 

774.8

 

667.8

 

16.0%

 

7.6%

Commentary is based on the performance in YTD 2022, unless stated otherwise.

Somatuline: in North America, sales fell by 3.6%4, despite continued demand growth, impacted by increased competition and adverse U.S. pricing, driven by an increased level of commercial rebates and unfavorable movements in channel mix, as well as lower wholesaler inventories. In Europe, sales declined by 9.3%4, reflecting the larger effects of the launches of generic lanreotide in more markets, including Germany, France, Spain and the Nordics. Sales in the Rest of the World grew by 34.5%4, a result of strong performances in several geographies, including Japan and Brazil

Decapeptyl: the performance was mainly driven by continued volume growth across all countries, higher volumes in China and Korea and favorable shipment phasing in Algeria. In the third quarter, sales were supported by a strong performance in China, partly reflecting the impact of a loosening of COVID-19 lockdown restrictions

Cabometyx: the performance reflected strong volume uptakes in renal cell carcinoma across most geographies, mainly as a second-line monotherapy and, more recently, as a first-line therapy in combination with nivolumab

Onivyde: sales growth was primarily driven by a solid performance in the U.S., as well as sales to Ipsen’s ex-U.S. partner. The decline in sales in the third quarter reflected the impact of the phasing of 2022 sales to the partner

Dysport: the performance in the year to date was driven by strong demand in most therapeutics markets, and similar growth in the aesthetics market, including increased sales to Ipsen’s partner, Galderma, especially in North America and Australia. The stronger growth in the third quarter was boosted by the catch-up from the recent manufacturing-capacity increase that benefitted supply to support aesthetics-market demand

Tazverik: sales, which are in the U.S., were consolidated from 1 September 2022

Total sales by geographical area

 

 

YTD
2022

 

YTD
2021

 

% change

 

Q3
2022

 

Q3
2021

 

% change

 

€m

 

€m

 

Actual

 

CER6

 

€m

 

€m

 

Actual

 

CER6

North America

 

759.2

 

649.8

 

16.8%

 

4.0%

 

279.9

 

246.8

 

13.4%

 

-2.6%

Europe7

 

924.7

 

887.3

 

4.2%

 

3.7%

 

301.1

 

297.5

 

1.2%

 

1.1%

Rest of the World

 

524.6

 

375.2

 

39.8%

 

32.5%

 

193.9

 

123.5

 

57.0%

 

43.7%

Total Sales

 

2,208.5

 

1,912.3

 

15.5%

 

9.5%

 

774.8

 

667.8

 

16.0%

 

7.6%

Commentary is based on the performance in YTD 2022.

North America: sales grew by 4.0%6, driven by a continued strong performance from Dysport in the therapeutics market and, in the aesthetics market, through Galderma, and from Onivyde, partly offset by a Somatuline sales decline of 3.6%6

Europe: sales growth of 3.7%6, mainly reflecting strong Cabometyx performances in France, Spain and Germany, and Decapeptyl’s continued market-share uptakes. Following the launch of generic lanreotide in some European markets, Somatuline sales declined by 9.3%6. Dysport sales grew by 7.6%6, driven by volume uptakes in the therapeutics market

Rest of the World: sales growth of 32.5%6, driven by solid volume growth in both Oncology and Neuroscience. In Oncology, the increase in Decapeptyl sales reflected the strong performance in China, share gains in several markets, and favorable shipment phasing in Algeria. The strong growth of Cabometyx was also a result of market-share gains across a number of geographies. The performance also reflected good Somatuline sales, including in Japan and Brazil. In Neuroscience, the strong growth of Dysport sales was a result of volume uptakes in both therapeutics and aesthetics markets, primarily in Latin America and Australia

Appendix: geographic breakdown of total sales by medicine

YTD

 

Total

 

North America

 

Europe

 

Rest of the World

 

2022

 

2021

 

% change

 

2022

 

2021

 

% change

 

2022

 

2021

 

% change

 

2022

 

2021

 

% change

 

€m

 

€m

 

Actual

 

CER8

 

€m

 

€m

 

Actual

 

CER8

 

€m

 

€m

 

Actual

 

CER8

 

€m

 

€m

 

Actual

 

CER8

Oncology

 

1,767.2

 

1,565.4

 

12.9%

 

6.9%

 

634.5

 

570.8

 

11.2%

 

-1.0%

 

789.3

 

756.2

 

4.4%

 

3.8%

 

343.4

 

238.4

 

44.1%

 

35.6%

Somatuline

 

911.9

 

874.4

 

4.3%

 

-2.8%

 

525.5

 

485.3

 

8.3%

 

-3.6%

 

292.7

 

322.1

 

-9.1%

 

-9.3%

 

93.7

 

67.0

 

39.8%

 

34.5%

Decapeptyl

 

396.0

 

332.6

 

19.1%

 

15.6%

 

0.0

 

0.0

 

-

 

-

 

221.2

 

200.4

 

10.4%

 

10.3%

 

174.7

 

132.2

 

32.2%

 

23.5%

Cabometyx

 

327.7

 

258.6

 

26.7%

 

24.1%

 

12.9

 

9.9

 

30.4%

 

18.8%

 

242.4

 

210.0

 

15.4%

 

15.1%

 

72.4

 

38.7

 

87.0%

 

74.2%

Onivyde

 

122.0

 

93.0

 

31.1%

 

17.1%

 

93.1

 

75.1

 

23.8%

 

10.1%

 

26.5

 

17.5

 

51.8%

 

36.5%

 

2.4

 

0.4

 

n/a9

 

n/a 9

Tazverik

 

2.8

 

0.0

 

n/a9

 

n/a 9

 

2.8

 

0.0

 

n/a9

 

n/a 9

 

0.0

 

0.0

 

-

 

-

 

0.0

 

0.0

 

-

 

-

Other Oncology

 

6.9

 

6.7

 

2.0%

 

1.6%

 

0.3

 

0.5

 

-45.1%

 

-50.0%

 

6.4

 

6.3

 

3.1%

 

3.2%

 

0.2

 

0.0

 

n/a9

 

n/a9

Neuroscience

 

407.7

 

309.6

 

31.7%

 

25.1%

 

116.7

 

70.8

 

64.8%

 

46.3%

 

110.9

 

103.0

 

7.7%

 

7.6%

 

180.1

 

135.8

 

32.6%

 

27.3%

Dysport

 

400.3

 

305.3

 

31.1%

 

24.8%

 

116.7

 

70.8

 

64.8%

 

46.3%

 

110.9

 

103.0

 

7.7%

 

7.6%

 

172.8

 

131.5

 

31.4%

 

26.5%

Other Neuroscience

 

7.3

 

4.3

 

70.5%

 

49.1%

 

0.0

 

0.0

 

-

 

-

 

0.0

 

0.0

 

-

 

-

 

7.3

 

4.3

 

70.5%

 

49.1%

Rare Disease

 

33.6

 

37.3

 

-9.8%

 

-12.5%

 

8.1

 

8.2

 

-1.5%

 

-12.3%

 

24.5

 

28.2

 

-13.0%

 

-13.1%

 

1.1

 

1.0

 

13.0%

 

4.6%

NutropinAq

 

20.8

 

24.5

 

-15.3%

 

-15.5%

 

0.0

 

0.0

 

-

 

-

 

19.9

 

23.7

 

-15.9%

 

-16.1%

 

0.8

 

0.8

 

3.6%

 

0.5%

Increlex

 

12.8

 

12.8

 

-0.2%

 

-7.4%

 

8.0

 

8.2

 

-2.8%

 

-13.4%

 

4.6

 

4.5

 

2.3%

 

2.5%

 

0.2

 

0.1

 

70.3%

 

25.6%

Total Sales

 

2,208.5

 

1,912.3

 

15.5%

 

9.5%

 

759.2

 

649.8

 

16.8%

 

4.0%

 

924.7

 

887.3

 

4.2%

 

3.7%

 

524.6

 

375.2

 

39.8%

 

32.5%

Q3

 

Total

 

North America

 

Europe

 

Rest of the World

 

2022

2021

% change

 

2022

2021

% change

 

2022

2021

% change

 

2022

2021

% change

 

€m

€m

Actual

CER10

 

€m

€m

Actual

CER10

 

€m

€m

Actual

CER10

 

€m

€m

Actual

CER10

Oncology

 

603.1

552.3

9.2%

1.2%

 

234.1

217.4

7.7%

-7.4%

 

248.8

254.1

-2.1%

-2.3%

 

120.2

80.8

48.8%

35.3%

Somatuline

 

311.9

313.0

-0.3%

-9.8%

 

193.6

183.7

5.4%

-9.4%

 

86.0

107.6

-20.1%

-19.9%

 

32.4

21.8

48.7%

36.1%

Decapeptyl

 

131.4

110.1

19.3%

14.9%

 

0.0

0.0

-

-

 

70.1

65.9

6.4%

6.6%

 

61.3

44.2

38.6%

27.2%

Cabometyx

 

115.5

91.8

25.9%

21.8%

 

4.2

3.3

28.4%

13.5%

 

84.7

73.9

14.6%

14.4%

 

26.6

14.6

82.6%

61.1%

Onivyde

 

38.8

35.2

10.1%

-5.3%

 

33.4

30.3

10.3%

-5.7%

 

5.4

4.7

14.6%

1.6%

 

0.0

0.2

n/a11

n/a11

Tazverik

 

2.8

0.0

n/a11

n/a11

 

2.8

0.0

n/a11

n/a11

 

0.0

0.0

-

-

 

0.0

0.0

-

-

Other Oncology

 

2.6

2.2

18.1%

18.2%

 

0.1

0.1

-36.3%

-43.6%

 

2.6

2.1

24.3%

24.9%

 

0.0

0.0

-

-

Neuroscience

 

160.7

103.8

54.8%

43.4%

 

42.6

26.7

59.7%

36.0%

 

44.9

34.7

29.3%

29.3%

 

73.3

42.4

72.7%

59.8%

Dysport

 

158.0

102.5

54.1%

43.3%

 

42.6

26.7

59.7%

36.0%

 

44.9

34.7

29.3%

29.3%

 

70.5

41.1

71.5%

60.0%

Other Neuroscience

 

2.7

1.3

n/a11

54.1%

 

0.0

0.0

-

-

 

0.0

0.0

-

-

 

2.7

1.3

n/a11

54.1%

Rare Disease

 

11.0

11.7

-5.4%

-9.3%

 

3.2

2.7

18.5%

2.7%

 

7.4

8.7

-14.6%

-14.6%

 

0.5

0.3

44.6%

33.3%

NutropinAq

 

6.3

7.5

-16.1%

-16.4%

 

0.0

0.0

-

-

 

5.9

7.2

-17.1%

-17.2%

 

0.3

0.3

9.1%

3.7%

Increlex

 

4.8

4.2

13.5%

3.3%

 

3.2

2.7

18.4%

2.7%

 

1.5

1.5

-2.7%

-2.1%

 

0.1

0.0

n/a11

n/a11

Total Sales

 

774.8

667.8

16.0%

7.6%

 

279.9

246.8

13.4%

-2.6%

 

301.1

297.5

1.2%

1.1%

 

193.9

123.5

57.0%

43.7%

Forward-looking statements

The forward-looking statements, objectives and targets contained herein are based on Ipsen’s management strategy, current views and assumptions. Such statements involve known and unknown risks and uncertainties that may cause actual results, performance or events to differ materially from those anticipated herein. All of the above risks could affect Ipsen’s future ability to achieve its financial targets, which were set assuming reasonable macroeconomic conditions based on the information available today. Use of the words ‘believes’, ‘anticipates’ and ‘expects’ and similar expressions are intended to identify forward-looking statements, including Ipsen’s expectations regarding future events, including regulatory filings and determinations. Moreover, the targets described in this document were prepared without taking into account external-growth assumptions and potential future acquisitions, which may alter these parameters. These objectives are based on data and assumptions regarded as reasonable by Ipsen. These targets depend on conditions or facts likely to happen in the future, and not exclusively on historical data. Actual results may depart significantly from these targets given the occurrence of certain risks and uncertainties, notably the fact that a promising medicine in early development phase or clinical trial may end up never being launched on the market or reaching its commercial targets, notably for regulatory or competition reasons. Ipsen must face or might face competition from generic medicine that might translate into a loss of market share. Furthermore, the research and development process involves several stages each of which involves the substantial risk that Ipsen may fail to achieve its objectives and be forced to abandon its efforts with regards to a medicine in which it has invested significant sums. Therefore, Ipsen cannot be certain that favorable results obtained during preclinical trials will be confirmed subsequently during clinical trials, or that the results of clinical trials will be sufficient to demonstrate the safe and effective nature of the medicine concerned. There can be no guarantees a medicine will receive the necessary regulatory approvals or that the medicine will prove to be commercially successful. If underlying assumptions prove inaccurate or risks or uncertainties materialize, actual results may differ materially from those set forth in the forward-looking statements. Other risks and uncertainties include but are not limited to, general industry conditions and competition; general economic factors, including interest rate and currency exchange rate fluctuations; the impact of pharmaceutical industry regulation and healthcare legislation; global trends toward healthcare cost containment; technological advances, new medicine and patents attained by competitors; challenges inherent in new-medicine development, including obtaining regulatory approval; Ipsen's ability to accurately predict future market conditions; manufacturing difficulties or delays; financial instability of international economies and sovereign risk; dependence on the effectiveness of Ipsen’s patents and other protections for innovative medicines; and the exposure to litigation, including patent litigation, and/or regulatory actions. Ipsen also depends on third parties to develop and market some of its medicines which could potentially generate substantial royalties; these partners could behave in such ways which could cause damage to Ipsen’s activities and financial results. Ipsen cannot be certain that its partners will fulfil their obligations. It might be unable to obtain any benefit from those agreements. A default by any of Ipsen’s partners could generate lower revenues than expected. Such situations could have a negative impact on Ipsen’s business, financial position or performance. Ipsen expressly disclaims any obligation or undertaking to update or revise any forward-looking statements, targets or estimates contained in this press release to reflect any change in events, conditions, assumptions or circumstances on which any such statements are based, unless so required by applicable law. Ipsen’s business is subject to the risk factors outlined in its registration documents filed with the French Autorité des Marchés Financiers. The risks and uncertainties set out are not exhaustive and the reader is advised to refer to Ipsen’s 2021 Universal Registration Document, available on ipsen.com.

_______________________________

1 Unaudited IFRS consolidated sales.

2 At constant exchange rates (CER), which excludes any foreign-exchange impact by recalculating the performance for the relevant period by applying the exchange rates used for the prior period.

3 Excludes any contribution from the Consumer HealthCare business, divested in July 2022.

4 At CER, which excludes any foreign-exchange impact by recalculating the performance for the relevant period by applying the exchange rates used for the prior period.

5 Not applicable.

6 At CER, which excludes any foreign-exchange impact by recalculating the performance for the relevant period by applying the exchange rates used for the prior period.

7 Defined in this announcement as the E.U., the U.K., Iceland, Liechtenstein, Norway and Switzerland.

8 At CER, which excludes any foreign-exchange impact by recalculating the performance for the relevant period by applying the exchange rates used for the prior period.

9 Not applicable.

10 At CER, which excludes any foreign-exchange impact by recalculating the performance for the relevant period by applying the exchange rates used for the prior period.

11 Not applicable.

 

Investors

Craig Marks

Vice President, Investor Relations

+44 (0)7584 349 193

Adrien Dupin de Saint-Cyr

Investor Relations Manager

+33 6 64 26 17 49

Media

Amy Wolf

Vice President and Head of Corporate Brand Strategy

and Communications

+41 79 576 07 23

Ioana Piscociu

Senior Manager,

Global Media Relations

+33 6 69 09 12 96

Source: Ipsen

FAQ

What are Ipsen's latest sales figures for YTD 2022?

Ipsen reported total sales of €2,208.5m for YTD 2022, a 15.5% increase from the previous year.

How did Ipsen's Oncology sales perform in Q3 2022?

Oncology sales increased by 9.2% in Q3 2022 compared to Q3 2021.

What is the forecast for Ipsen's financial performance in FY 2022?

Ipsen expects total-sales growth of greater than 7% at constant exchange rates for FY 2022.

What impact did the acquisition of Epizyme have on Ipsen?

The acquisition of Epizyme strengthened Ipsen's presence in the Oncology market.

What challenges did Ipsen face regarding Somatuline sales?

Somatuline sales fell by 2.8% due to increased competition and unfavorable pricing in the U.S. and Europe.

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