Iovance Biotherapeutics to Present at American Association for Cancer Research (AACR) 2022 Annual Meeting
Iovance Biotherapeutics (NASDAQ: IOVA) announced the acceptance of two abstracts for presentation at the AACR 2022 Annual Meeting, scheduled for April 8-13, 2022, in New Orleans, Louisiana, and virtually. The first abstract focuses on the preclinical activity of genetically modified PDCD-1 knockout TIL cell therapy, presented by Arvind Natarajan. The second abstract highlights a Phase 2 multicenter trial (IOV-LUN-202) of autologous TIL therapy in metastatic non-small cell lung cancer, presented by Jason Alan Chesney. Posters will be available from April 8 in the Virtual ePoster Hall.
- None.
- None.
SAN CARLOS, Calif., March 08, 2022 (GLOBE NEWSWIRE) -- Iovance Biotherapeutics, Inc. (NASDAQ: IOVA), a late-stage biotechnology company developing novel T cell-based cancer immunotherapies, today announced the acceptance of two abstracts for presentation at the upcoming American Association for Cancer Research (AACR) 2022 Annual Meeting April 8-13, 2022 in New Orleans, Louisiana and virtual. Details for the abstracts are as follows:
- Abstract Title: Preclinical activity and manufacturing feasibility of genetically modified PDCD-1 knockout (KO) tumor infiltrating lymphocyte (TIL) cell therapy
Presenting Author: Arvind Natarajan, Ph.D., Iovance Biotherapeutics, Inc.
Abstract Number: 2746
Poster Session: Tuesday, April 12, 2022, 9:00 a.m. - 12:30 p.m. ET, New Orleans Convention Center, Exhibit Halls D-H, Poster Section 30
- Abstract Title: Trial in progress: A phase 2 multicenter study (IOV-LUN-202) of autologous tumor-infiltrating lymphocyte (TIL) cell therapy (LN-145) in patients with metastatic non-small cell lung cancer (mNSCLC)
Presenting Author: Jason Alan Chesney, M.D., Ph.D., Director, James Graham Brown Cancer Center, University of Louisville
Abstract Number: CT130
Poster Session: Monday, April 11, 2022, 9:00 a.m. - 12:30 p.m. ET, New Orleans Convention Center, Exhibit Halls D-H, Poster Section 34
Posters will also be available starting at 1:00 p.m. ET on Friday, April 8, in the Virtual ePoster Hall at www.aacr.org.
About Iovance Biotherapeutics, Inc.
Iovance Biotherapeutics aims to be the global leader in innovating, developing and delivering tumor infiltrating lymphocyte (TIL) therapies for patients with cancer. We are pioneering a transformational approach to cure cancer by harnessing the human immune system’s ability to recognize and destroy diverse cancer cells in each patient. Our lead late-stage TIL product candidate, lifileucel for metastatic melanoma, has the potential to become the first approved one-time cell therapy for a solid tumor cancer. The Iovance TIL platform has demonstrated promising clinical data across multiple solid tumors. We are committed to continuous innovation in cell therapy, including gene-edited cell therapy, that may extend and improve life for patients with cancer. For more information, please visit www.iovance.com.
Forward-Looking Statements
Certain matters discussed in this press release are “forward-looking statements” of Iovance Biotherapeutics, Inc. (hereinafter referred to as the “Company,” “we,” “us,” or “our”) within the meaning of the Private Securities Litigation Reform Act of 1995 (the “PSLRA”). All such written or oral statements made in this press release, other than statements of historical fact, are forward-looking statements and are intended to be covered by the safe harbor for forward-looking statements provided by the PSLRA. Without limiting the foregoing, we may, in some cases, use terms such as “predicts,” “believes,” “potential,” “continue,” “estimates,” “anticipates,” “expects,” “plans,” “intends,” “forecast,” “guidance,” “outlook,” “may,” “could,” “might,” “will,” “should” or other words that convey uncertainty of future events or outcomes and are intended to identify forward-looking statements. Forward-looking statements are based on assumptions and assessments made in light of management’s experience and perception of historical trends, current conditions, expected future developments and other factors believed to be appropriate. Forward-looking statements in this press release are made as of the date of this press release, and we undertake no duty to update or revise any such statements, whether as a result of new information, future events or otherwise. Forward-looking statements are not guarantees of future performance and are subject to risks, uncertainties and other factors, many of which are outside of our control, that may cause actual results, levels of activity, performance, achievements and developments to be materially different from those expressed in or implied by these forward-looking statements. Important factors that could cause actual results, developments and business decisions to differ materially from forward-looking statements are described in the sections titled "Risk Factors" in our filings with the Securities and Exchange Commission, including our most recent Annual Report on Form 10-K and Quarterly Reports on Form 10-Q, and include, but are not limited to, the following substantial known and unknown risks and uncertainties inherent in our business: the effects of the COVID-19 pandemic; risks related to the timing of and our ability to successfully develop, submit, obtain and maintain U.S. Food and Drug Administration (“FDA”) or other regulatory authority approval of, or other action with respect to, our product candidates, and our ability to successfully commercialize any product candidates for which we obtain FDA approval; preliminary and interim clinical results, which may include efficacy and safety results, from ongoing clinical trials or cohorts may not be reflected in the final analyses of our ongoing clinical trials or subgroups within these trials or in other prior trials or cohorts; the risk that enrollment may need to be adjusted for our trials and cohorts within those trials based on FDA and other regulatory agency input; the changing landscape of care for cervical cancer patients may impact our clinical trials in this indication; the risk that we may be required to conduct additional clinical trials or modify ongoing or future clinical trials based on feedback from the FDA or other regulatory authorities; the risk that our interpretation of the results of our clinical trials or communications with the FDA may differ from the interpretation of such results or communications by the FDA; the acceptance by the market of our product candidates and their potential reimbursement by payors, if approved; our ability or inability to manufacture our therapies using third party manufacturers or our own facility may adversely affect our potential commercial launch; the results of clinical trials with collaborators using different manufacturing processes may not be reflected in our sponsored trials; the risk that unanticipated expenses may decrease our estimated cash balances and forecasts and increase our estimated capital requirements; and other factors, including general economic conditions and regulatory developments, not within our control.
CONTACTS
Iovance Biotherapeutics, Inc:
Sara Pellegrino, IRC
Vice President, Investor Relations & Public Relations
650-260-7120 ext. 264
Sara.Pellegrino@iovance.com
Jen Saunders
Director, Investor Relations & Public Relations
650-260-7120 ext. 264
Jen.Saunders@iovance.com
FAQ
What abstracts did Iovance Biotherapeutics present at the AACR 2022 Annual Meeting?
When is the AACR 2022 Annual Meeting taking place?
What is the focus of the first abstract presented by Iovance at AACR 2022?
Who is the presenting author of the second abstract from Iovance?
What is the significance of the trial IOV-LUN-202 mentioned in the press release?
Where can I find the posters presented by Iovance at the AACR 2022?
