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Insmed, Inc. - INSM STOCK NEWS

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Insmed, Inc. (Symbol: INSM) is a global biopharmaceutical company headquartered in Bridgewater, NJ, with a mission to transform the lives of patients with serious and rare diseases. The company is committed to developing and bringing to market therapies that significantly improve patient lives, focusing on the entire patient journey from diagnosis and treatment to daily living.

Insmed's flagship product, ARIKAYCE (amikacin liposome inhalation suspension), is approved in the US for treating Mycobacterium Avium Complex (MAC) lung disease in adult patients who have limited or no alternative treatment options. ARIKAYCE, utilizing Insmed's proprietary PULMOVANCE® liposomal technology, delivers amikacin directly to the lungs, reducing systemic exposure and associated toxicities. It is administered using the Lamira® Nebulizer System developed by PARI Pharma GmbH, known for its efficiency and portability.

The company’s clinical pipeline includes multiple promising candidates. Notable among them is Brensocatib, a novel oral reversible inhibitor of dipeptidyl peptidase 1 (DPP1). It is being developed for treating non-cystic fibrosis bronchiectasis and other neutrophil-mediated diseases. Another significant pipeline product is TPIP (Treprostinil Palmitil Inhalation Powder), an inhaled formulation being evaluated for pulmonary arterial hypertension and other serious pulmonary disorders.

Insmed has demonstrated robust financial performance, with significant revenue growth driven by ARIKAYCE. The company continues to invest heavily in research and development, with plans to expand its product portfolio and market reach globally.

Insmed's strategic partnerships and collaborations play a crucial role in advancing its mission. These include collaborations with PARI Pharma for the Lamira® Nebulizer System and AstraZeneca AB for utilizing their expertise in respiratory diseases.

Recent updates include positive financial results for the third quarter of 2023, robust revenue growth from ARIKAYCE, and significant progress in clinical trials. Noteworthy are the topline results from the Phase 3 ASPEN study for Brensocatib, indicating its potential as a first-in-class treatment. Insmed plans to file a New Drug Application (NDA) with the FDA for Brensocatib by late 2024, aiming for a potential launch in 2025.

The company is also advancing its early-stage research engine, exploring innovative technologies such as artificial intelligence-driven protein engineering and gene therapy, positioning itself at the forefront of biopharmaceutical innovation.

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Insmed Incorporated (Nasdaq: INSM) announced on July 8, 2021, the granting of inducement awards to 12 new employees, approved by the Compensation Committee in accordance with NASDAQ Listing Rule 5635(c)(4). Each employee received options to purchase 72,350 shares of common stock at an exercise price of $29.47, the closing price on July 1, 2021. The options have a ten-year term with a four-year vesting schedule. Insmed is focused on developing therapies for serious and rare diseases, including a commercial product approved in the U.S., Europe, and Japan.

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Insmed Incorporated (Nasdaq:INSM) announced inducement awards to 11 new employees as per NASDAQ Listing Rule 5635(c)(4). The awards, approved by the Compensation Committee, include options to purchase a total of 59,020 shares at an exercise price of $25.17, equal to the closing price on June 1, 2021. The options have a ten-year term, with a four-year vesting schedule. Insmed focuses on transforming the lives of patients with serious and rare diseases, offering therapies for chronic lung diseases and advancing a pipeline targeting serious unmet medical needs.

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Insmed Incorporated (Nasdaq: INSM), a biopharmaceutical company, announced its management will present at two upcoming virtual investor events: the Jefferies Virtual Healthcare Conference on June 1, 2021, at 9:00 a.m. ET, and the Goldman Sachs 42nd Annual Global Healthcare Conference on June 9, 2021, at 2:10 p.m. ET. Both presentations will be webcast live and archived for 30 days. Insmed focuses on transforming the lives of patients with serious diseases and has a robust pipeline of therapies for unmet medical needs.

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Insmed has showcased its clinical development portfolio at the ATS 2021 International Conference with data from nine presentations on ARIKAYCE, brensocatib, and TPIP. Key findings include a study indicating higher mortality in COPD patients with NTM lung disease, emphasizing the need for effective management. ARIKAYCE showed a favorable safety profile and effective culture conversion in MAC lung disease. Brensocatib demonstrated good tolerability in early trials, and TPIP exhibited superior therapeutic benefits in preclinical studies compared to existing treatments for pulmonary arterial hypertension.

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Insmed announced the closing of a registered underwritten public offering of 11,500,000 shares of common stock at $25.00 per share and $575 million in 0.75% convertible senior notes due 2028. The offerings raised gross proceeds of $287.5 million from the common stock and $575 million from the notes. A portion of the notes' proceeds will repurchase $225 million of existing 1.75% convertible senior notes due 2025. The funds will support the commercialization of ARIKAYCE and research on brensocatib and TPIP, among other corporate purposes.

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Insmed has priced a public offering of 10 million shares at $25 each, raising $250 million, alongside a $500 million offering of 0.75% convertible senior notes due 2028. A portion of the notes proceeds will repurchase $225 million of existing convertible notes due 2025. The offerings, set to close by May 13, 2021, are expected to bolster Insmed's funds for commercialization and development of ARIKAYCE and other products. The convertible notes feature a conversion price of approximately $32.50 per share, with a contingent option for underwriters to purchase additional shares and notes.

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Insmed Incorporated (Nasdaq: INSM) plans to offer $250 million of common stock and $500 million in convertible senior notes due 2028. Proceeds will partially fund the repurchase of existing convertible senior notes due 2025 and support the commercialization of ARIKAYCE and development of other product candidates. The offerings include options for underwriters to purchase an additional 15% of shares and notes. The offerings are subject to market conditions and may not be completed as planned.

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Insmed Incorporated (Nasdaq: INSM) announced the granting of inducement awards to nine new employees as part of their employment agreements, in line with NASDAQ Listing Rule 5635(c)(4). The awards, approved by the Compensation Committee, consist of options to purchase 49,410 shares of common stock at an exercise price of $32.94 per share, the closing price on May 3, 2021. These options will have a ten-year term with a four-year vesting schedule. Insmed focuses on developing therapies for serious and rare diseases, including chronic lung conditions.

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Insmed reported its Q1 2021 financial results, highlighting total revenue of $40.2 million, up from $36.9 million in Q1 2020. The net loss increased to $91.6 million or $0.89 per share, compared to $66.4 million or $0.74 per share a year earlier. ARIKAYCE was approved in Japan, expanding its market presence, and patient enrollment for ongoing clinical studies continues. The company maintains a cash position of $409.8 million and plans significant investments in clinical and commercialization activities throughout 2021.

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Insmed Incorporated (Nasdaq: INSM) has announced the release date for its first quarter 2021 financial results as May 6, 2021. A conference call for investors will take place at 8:30 a.m. ET on the same day, where management will discuss the financial outcomes and provide a business update. Interested parties can join the call through a provided dial-in number or via a live webcast on the company's website. The company focuses on transforming the lives of patients with serious and rare diseases, having a first-in-disease therapy approved in the US, Europe, and Japan.

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FAQ

What is the current stock price of Insmed (INSM)?

The current stock price of Insmed (INSM) is $66.29 as of November 15, 2024.

What is the market cap of Insmed (INSM)?

The market cap of Insmed (INSM) is approximately 12.1B.

What is Insmed's primary mission?

Insmed's mission is to transform the lives of patients with serious and rare diseases by developing and bringing to market innovative therapies.

What is ARIKAYCE?

ARIKAYCE (amikacin liposome inhalation suspension) is Insmed's first commercial product, approved for treating Mycobacterium Avium Complex (MAC) lung disease in adult patients with limited or no alternative treatment options.

What are Brensocatib and TPIP?

Brensocatib is an oral reversible inhibitor of dipeptidyl peptidase 1 (DPP1) being developed for non-cystic fibrosis bronchiectasis and other inflammatory diseases. TPIP is an inhaled formulation of treprostinil for treating pulmonary arterial hypertension and other pulmonary disorders.

Where is Insmed headquartered?

Insmed is headquartered in Bridgewater, New Jersey, with additional offices and research locations worldwide.

What are Insmed's recent financial highlights?

Insmed reported significant revenue growth in the third quarter of 2023, particularly from ARIKAYCE sales, and continues to show strong financial performance.

What are the strategic partnerships of Insmed?

Insmed collaborates with PARI Pharma for the Lamira® Nebulizer System and AstraZeneca AB to leverage their expertise in respiratory diseases.

What are the latest developments in Insmed's clinical trials?

Recent highlights include positive topline results from the Phase 3 ASPEN study for Brensocatib, which showed significant treatment benefits, and ongoing evaluations of TPIP for various serious pulmonary conditions.

What is Insmed's approach to early-stage research?

Insmed is advancing an early-stage research engine encompassing innovative technologies, including artificial intelligence-driven protein engineering and gene therapy.

What is the Lamira® Nebulizer System?

The Lamira® Nebulizer System, developed by PARI Pharma, is a portable device used to administer ARIKAYCE efficiently through aerosolization.

When does Insmed plan to file an NDA for Brensocatib?

Insmed plans to file a New Drug Application (NDA) with the FDA for Brensocatib in the fourth quarter of 2024, with hopes for a U.S. launch in mid-2025.

Insmed, Inc.

Nasdaq:INSM

INSM Rankings

INSM Stock Data

12.06B
178.90M
0.91%
108.31%
7.66%
Biotechnology
Pharmaceutical Preparations
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United States of America
BRIDGEWATER