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Inhibrx Biosciences Inc - INBX STOCK NEWS

Welcome to our dedicated page for Inhibrx Biosciences news (Ticker: INBX), a resource for investors and traders seeking the latest updates and insights on Inhibrx Biosciences stock.

Overview

Inhibrx Biosciences Inc (INBX) is a clinical-stage biopharmaceutical company focused on the innovative development of novel biologic therapeutic candidates. Utilizing proprietary modular protein engineering platforms, the company is committed to addressing significant unmet medical needs in oncology and rare diseases through precise, target-centric therapeutic design.

Proprietary Technology and Engineering Excellence

At the heart of Inhibrx Biosciences’ operations is its advanced protein engineering technology. This industry-leading platform enables the development of multivalent formats that allow for precise adjustment of antibody valency. The flexibility of this modular approach provides a tailored agonist function, ensuring each therapeutic candidate is optimized for complex biological targets.

Clinical Pipeline and Therapeutic Candidates

Inhibrx Biosciences has built a robust clinical pipeline featuring a diverse range of novel biologic candidates. These candidates are meticulously engineered using multivalent designs to enhance therapeutic efficacy and safety. The company’s approach is deeply rooted in the application of innovative protein engineering methodologies that help accelerate the path from preclinical research to clinical validation.

Business Model and Market Position

The business model centers on advancing clinical-stage therapeutics using a flexible, data-driven approach. Rather than relying on traditional models, Inhibrx Biosciences emphasizes the use of cutting-edge modular platforms to generate bio-optimized therapeutic candidates. This focus on precision and adaptability not only differentiates the company from its peers but also positions it as a forward-thinking entity in the competitive biopharmaceutical landscape.

Strategic Partnerships and Financial Structuring

Inhibrx Biosciences has secured strategic partnerships and innovative financing solutions to support its clinical programs. Such collaborations provide the company with the necessary capital and operational flexibility to continue its research and development efforts. These partnerships, including tailored term loan facilities from specialized financial institutions, ensure that the company maintains a robust infrastructure for ongoing clinical investigations.

Operational Excellence and Scientific Rigor

The company upholds stringent standards of scientific and operational excellence. Through its proprietary protein engineering techniques and commitment to exhaustive preclinical and clinical evaluations, Inhibrx Biosciences ensures its therapeutic candidates are developed with the highest standards of quality. This rigorous approach reinforces trust and credibility among industry analysts and investors alike.

Expert Insights and Industry Relevance

  • Protein Engineering
  • Biologic Therapeutics
  • Multivalent Formats

By integrating advanced protein engineering with a deep understanding of disease biology, Inhibrx Biosciences continues to innovate in the development of precision-targeted therapies. This expert approach not only augments its clinical pipeline but also contributes to a broader industry narrative of overcoming complex therapeutic challenges in oncology and orphan diseases.

Rhea-AI Summary

On June 30, 2022, Inhibrx, Inc. (Nasdaq: INBX) announced the completion of Phase 1 dose escalation for its novel targeted 4-1BB agonist, INBRX-105, in combination with Keytruda®. The trial, involving 30 patients, indicated a favorable safety profile and durable responses. Additionally, the company secured $60 million in funding through its Loan Agreement with Oxford Finance, adjusting its cash balance to approximately $176 million. The next phase of trials is set to include around 90 patients, with initial results expected in early 2023.

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Inhibrx, Inc. (Nasdaq: INBX) will present details on its INBRX-109 Phase 2 trial for conventional chondrosarcoma at the 2022 ASCO Annual Meeting from June 3-7, 2022. The trial aims to establish a placebo-controlled methodology for evaluating INBRX-109, a DR5 agonist antibody. Preliminary Phase 1 results showed efficacy in 89% of patients, with a median progression-free survival of 7.4 months. The presentation, led by Dr. Sant P. Chawla, will take place on June 5, 2022, from 9 a.m. to 11 a.m. CST, and the poster will be available online.

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Inhibrx Inc. announces favorable topline results from a Phase 1 clinical trial of INBRX-101, a recombinant human AAT-Fc fusion protein for treating alpha-1 antitrypsin deficiency (AATD). The study involved 31 patients and showed no severe drug-related adverse events, with mild and reversible issues reported. The drug achieved an average functional alpha-1 antitrypsin (AAT) level of 40.4 µM after the third dose, surpassing the current standard of care's 17.8 µM. Inhibrx believes INBRX-101 could reduce infusion frequency significantly, offering a more convenient treatment option.

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Inhibrx, Inc. (Nasdaq: INBX) reported its Q1 2022 financial results and corporate updates on May 9, 2022. The company reported cash and equivalents of $143.5 million, an increase from $131.3 million at year-end 2021. R&D expenses rose to $24.9 million, compared to $16.4 million in Q1 2021. General and administrative expenses also increased to $5.1 million. The net loss for Q1 2022 was $31.3 million ($0.80 per share), up from $19.3 million ($0.51 per share) in Q1 2021. Recent highlights include FDA orphan-drug designation for INBRX-101 and a $130 million loan agreement amendment.

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Inhibrx, Inc. (Nasdaq: INBX) announced the establishment of a Scientific Advisory Board (SAB) for its clinical program INBRX-101, aimed at treating alpha-1 antitrypsin deficiency (AATD). The board consists of leading experts in AATD, who will collaborate with Inhibrx's management to advance INBRX-101 towards regulatory approval. The drug has shown promise as a potentially best-in-class treatment, addressing a significant unmet need in AATD, which affects about 100,000 patients in the U.S. Current standard treatments require inconvenient weekly dosing, while INBRX-101 may allow for monthly administration.

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Inhibrx (Nasdaq: INBX) announced that late-breaking data on INBRX-101 will be presented at the American Thoracic Society (ATS) 2022 Conference from May 13-18, 2022, in San Francisco, CA. The oral presentation, led by Mark Brantly, focuses on a novel recombinant AAT-Fc fusion protein for patients with Alpha-1 Antitrypsin Deficiency (AATD). It will occur on May 16, while a related poster presentation will take place on May 17. AATD affects about 100,000 individuals in the US, leading to serious lung issues. INBRX-101 has shown promising early results in an ongoing Phase 1 trial.

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Inhibrx, Inc. (Nasdaq: INBX) announced the presentation of data from its clinical programs INBRX-121 and INBRX-130 at the 2022 AACR Annual Meeting, scheduled from April 8-13, 2022, in New Orleans, LA. INBRX-121 enhances NK cell tumor killing, while INBRX-130 is a bispecific antibody targeting 5T4 antigen on solid tumors. Both platforms aim to expand Inhibrx's oncology pipeline and improve treatment outcomes. Posters will be available on-demand from April 8 to July 13, 2022, on AACR's website and Inhibrx's site.

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Inhibrx, Inc. (Nasdaq: INBX) announced that the FDA has granted orphan-drug designation for INBRX-101 to treat alpha-1 antitrypsin deficiency (AATD). This designation acknowledges the unmet medical need for new therapies in AATD, which affects approximately 100,000 patients in the U.S. INBRX-101 is designed for once-monthly dosing and aims to improve AAT levels significantly. Orphan designation offers benefits, including financial incentives and potential seven years of market exclusivity upon approval, enhancing Inhibrx's position in the biotech sector.

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Inhibrx, Inc. (Nasdaq: INBX) reported its financial results for Q4 and FY 2021, highlighting a net loss of $21.2 million for Q4, or $0.55 per share, compared to $17.6 million in Q4 2020. The annual net loss increased to $81.8 million, or $2.15 per share, from $76.1 million in FY 2020. The company had cash and equivalents of $131.3 million as of December 31, 2021. Recent highlights include FDA orphan-drug designation for INBRX-109 and initial Phase 1 results for INBRX-106, now expected to announce further data in H2 2022.

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Inhibrx, Inc. (Nasdaq: INBX) has amended its loan agreement with Oxford Finance, enhancing its financial flexibility amid a challenging equity market. The amendment allows for up to $130 million in new term loans, with $40 million available immediately and additional funding contingent upon key clinical trial developments. The revised terms extend loan maturity to January 2027 at an interest rate of 8.19%. This deal strengthens Inhibrx's balance sheet and supports ongoing clinical programs, including INBRX-105 and INBRX-101.

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FAQ

What is the current stock price of Inhibrx Biosciences (INBX)?

The current stock price of Inhibrx Biosciences (INBX) is $13.34 as of April 4, 2025.

What is the market cap of Inhibrx Biosciences (INBX)?

The market cap of Inhibrx Biosciences (INBX) is approximately 197.5M.

What does Inhibrx Biosciences Inc specialize in?

Inhibrx Biosciences Inc specializes in the development of novel biologic therapeutic candidates using proprietary modular protein engineering platforms.

How does the company utilize protein engineering in its therapies?

The company employs advanced protein engineering to design multivalent formats, allowing precise tuning of therapeutic candidates to optimize target-specific agonist functions.

What are the primary therapeutic focus areas of the company?

Inhibrx Biosciences primarily focuses on addressing unmet needs in oncology and rare or orphan diseases through innovative biologic therapies.

How does Inhibrx differentiate itself from competitors?

The company differentiates itself through its proprietary modular approach to protein engineering, enabling highly customizable and targeted therapeutic solutions that specifically address complex disease biology.

What stage is Inhibrx Biosciences in regarding its clinical pipeline?

Inhibrx Biosciences operates as a clinical-stage biopharmaceutical company, advancing its diverse pipeline through rigorous preclinical studies and clinical trials.

How is the company supporting its clinical development?

It supports its clinical development efforts through strategic partnerships and innovative financial structuring, which provide the necessary capital and operational flexibility for continued R&D.

What advantages does the multivalent format offer?

The multivalent format allows for precise modulation of therapeutic activity, enhancing both efficacy and safety by optimizing the engagement of specific biological targets.

Where can investors find reliable information on Inhibrx Biosciences?

Investors can obtain comprehensive, unbiased insights from trusted sources like Stock Titan, which provides detailed descriptions and analyses of companies like Inhibrx Biosciences.
Inhibrx Biosciences Inc

Nasdaq:INBX

INBX Rankings

INBX Stock Data

197.52M
9.50M
26.96%
70%
8.19%
Biotechnology
Biological Products, (no Disgnostic Substances)
Link
United States
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