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IN8bio, Inc. (Nasdaq: INAB) is a clinical-stage biotechnology company pioneering the development of novel therapies aimed at treating various cancers. Using allogeneic, autologous, and genetically modified gamma-delta T cells, IN8bio is revolutionizing cancer treatment. The company’s mission is to create groundbreaking therapies that harness the power of the body’s immune system to target and destroy cancer cells.
IN8bio's robust portfolio includes several promising product candidates:
- INB-400: Aimed at treating newly diagnosed glioblastoma (GBM), this product is currently in a Phase 2 clinical trial.
- INB-100: Designed for patients with high-risk leukemias undergoing hematopoietic stem cell transplantation, this therapy is under Phase 1 clinical trials.
- INB-200: Another promising candidate targeting GBM, it has shown encouraging preliminary clinical data at the 2024 ASCO Annual Meeting.
- Additional products, like INB-300 and INB-500, are in various stages of development targeting both solid and liquid tumors.
Recently, IN8bio disclosed significant advancements in the treatment of GBM, utilizing their innovative gamma-delta T cell-based adoptive cellular therapy. A peer-reviewed publication highlighted the strategy and future direction of their novel treatment methods.
Financially, IN8bio extends its cash runway into 2025, bolstered by additional capital from a private placement in December 2023. The company continues to pursue more funding to advance its clinical trials and achieve its milestones.
IN8bio's groundbreaking work has garnered attention in the biotech field, especially for its genetically modified gamma-delta T cells, which are the first to be advanced into clinical trials. The company’s approach shows great potential in improving progression-free survival (PFS) and overall survival (OS) rates for GBM and other cancers.
For investors and stakeholders, IN8bio provides exciting opportunities as it moves towards commercializing its therapies, aiming to address significant unmet medical needs in oncology. For more information, please visit IN8bio.
IN8bio, Inc. (Nasdaq: INAB) announced that CEO William Ho will participate in a fireside chat at the H.C. Wainwright & Co. 24th Annual Global Investment Conference on September 14, 2022, at 10:30 a.m. ET. The event will be live-streamed on the IN8bio website, with a replay available for 90 days. IN8bio specializes in gamma-delta T cell therapies for cancer, focusing on innovative treatments for glioblastoma and leukemia. The company is conducting Phase 1 trials for its lead products, INB-200 and INB-100, while exploring preclinical programs for various solid tumors.
IN8bio, Inc. (Nasdaq: INAB) has appointed Dr. Michael R. Bishop to its Scientific Advisory Board. Dr. Bishop is a renowned expert in cellular therapy and oncology, currently serving at the University of Chicago. His extensive experience in hematologic malignancies and stem cell transplantation is expected to bolster IN8bio’s development of gamma-delta T cell therapies. The company is advancing its clinical programs, including Phase 1 trials for glioblastoma and leukemia treatments, leveraging its DeltEx platform, which aims to enhance the efficacy of cell therapies.
IN8bio, Inc. (Nasdaq: INAB) announced its participation in several key conferences throughout September 2022. CEO William Ho will join the Cell Therapy Panel at Citi’s Annual BioPharma Conference in Boston on September 7. He will also partake in a Fireside Chat at H.C. Wainwright from September 12-15, with a session on September 14. Kate Rochlin, COO, will present at the BioProcess International Conference in Boston on September 28. Additionally, Lawrence Lamb, CSO, will present at the Sixth International Cancer Immunotherapy Conference in New York on September 30. IN8bio focuses on gamma-delta T cell therapies.
IN8bio, Inc. (Nasdaq: INAB) has reported that the underwriter of its recent public offering, which closed on August 16, 2022, partially exercised its option to purchase 268,949 additional shares at $1.90 each, adding approximately $0.5 million in gross proceeds. This brings the total number of shares sold to 5,663,686, with gross proceeds now totaling around $10.75 million. The offering was conducted under a registration statement declared effective on August 11, 2022.
IN8bio, Inc. (Nasdaq: INAB) successfully closed an underwritten public offering of 5,394,737 shares of its common stock at $1.90 per share, generating approximately $10.25 million in gross proceeds. The offering, managed by H.C. Wainwright & Co., included a 30-day option for the underwriter to purchase an additional 657,894 shares. This transaction was facilitated through a registration statement filed with the SEC, effective August 11, 2022. The funds are intended to support the company's clinical development of gamma-delta T cell therapies.
IN8bio recently announced a preclinical program for iPSC-derived gamma-delta T cells, presenting findings at the ASGCT Annual Meeting. The Phase 1 trial of INB-200 showed five of six patients exceeded expected progression-free survival (PFS), while two surpassed overall survival (OS) benchmarks. INB-100 Phase 1 trial data revealed two of three leukemia patients relapse-free at two years. The company appointed new executives to bolster its management team. Financially, R&D expenses rose to $3.5 million, with a net loss of $7.2 million for Q2 2022, and cash reserves decreased to $25.7 million.
IN8bio announced a public offering of 5,394,737 shares at $1.90 each, expected to close by August 16, 2022. The offering could generate approximately $10.25 million before expenses. H.C. Wainwright & Co. is the sole book-running manager, with an option for additional 657,894 shares. The registration statement was declared effective on August 11, 2022. IN8bio focuses on innovative gamma-delta T cell therapies for tumors, emphasizing its DeltEx platform's capabilities.
IN8bio, Inc. (Nasdaq: INAB) announced promising progress in its Phase 1 trial of INB-100 for high-risk relapsed acute myeloid leukemia (AML) patients. All three patients treated remain alive and disease-free for more than one year post-transplant, with two patients exceeding two years in complete remission. The therapy shows a manageable safety profile, with no severe adverse effects or dose-limiting toxicities reported. The data suggests potential for improved cure rates in AML without significant added risks, with further patient data expected later in 2022.
IN8bio, Inc. (Nasdaq: INAB) announced the issuance of a new European patent covering its Drug Resistant Immunotherapy (DRI) platform, expanding its intellectual property to include NK cells alongside gamma-delta T cells. This patent enhances IN8bio’s position in developing cellular therapies for solid tumors, emphasizing its innovative approach to combat cancer through genetically engineered immune cells. The company is actively advancing its pipeline, including ongoing Phase 1 trials for INB-200 and INB-100, aimed at treating glioblastoma and leukemia, respectively.
IN8bio, Inc. (Nasdaq: INAB) announced the appointment of Kenneth R. LaMontagne, Ph.D., as Senior Vice President of Business Development, aiming to enhance partnership strategies for gamma-delta T cell therapies. Dr. LaMontagne brings over 20 years of experience in cell therapies and oncology, with a history of significant transaction execution in his past roles at Artisan Bio and Bristol Myers Squibb. CEO William Ho emphasized the strategic importance of this leadership addition to increase shareholder value and advance the company's comprehensive pipeline in clinical development.
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