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IN8bio Announces Plenary Oral Presentation at the 2024 Society for Neuro-Oncology (SNO) Annual Meeting

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IN8bio (Nasdaq: INAB) announced an upcoming plenary oral presentation at the 29th Annual Meeting of the Society for Neuro-Oncology (SNO) in November 2024. The presentation will provide extended follow-up data from the Phase 1 trial of INB-200, their gamma-delta T cell therapy for newly diagnosed glioblastoma.

Previous data presented at ASCO in June 2024 showed that 92% of evaluable patients exceeded the median progression-free survival of 7 months typically observed with standard-of-care therapy. The presentation will be delivered by Dr. Mina Lobbous from Cleveland Clinic Lerner College of Medicine.

IN8bio (Nasdaq: INAB) ha annunciato una prossima presentazione orale plenaria alla 29ª Conferenza Annuale della Society for Neuro-Oncology (SNO) prevista per novembre 2024. La presentazione fornirà dati di follow-up estesi dal trial di Fase 1 di INB-200, la loro terapia con cellule T gamma-delta per i glioblastomi newly diagnosticati.

I dati precedenti presentati all'ASCO nel giugno 2024 hanno mostrato che il 92% dei pazienti evaluabili ha superato la mediana della sopravvivenza libera da progressione di 7 mesi tipicamente osservata con la terapia standard. La presentazione sarà tenuta dalla Dott.ssa Mina Lobbous del Cleveland Clinic Lerner College of Medicine.

IN8bio (Nasdaq: INAB) anunció una próxima presentación plenaria oral en la 29ª Reunión Anual de la Society for Neuro-Oncology (SNO) en noviembre de 2024. La presentación proporcionará datos de seguimiento ampliados del ensayo de Fase 1 de INB-200, su terapia con células T gamma-delta para glioblastoma recién diagnosticado.

Datos anteriores presentados en ASCO en junio de 2024 mostraron que el 92% de los pacientes evaluables superaron la mediana de supervivencia libre de progresión de 7 meses que se observa típicamente con la terapia estándar. La presentación será realizada por la Dra. Mina Lobbous del Cleveland Clinic Lerner College of Medicine.

IN8bio (Nasdaq: INAB)는 2024년 11월에 열리는 제29회 신경종양학회(SNO) 연례회의에서 발표할 예정이다. 이번 발표에서는 새로 진단된 교모세포종에 대한 그들의 감마 델타 T 세포 치료제인 INB-200의 1상 시험에서의 연장된 후속 데이터가 제공될 예정이다.

2024년 6월 ASCO에서 발표된 이전 데이터에 따르면, 평가 가능한 환자 중 92%가 표준 치료에서 일반적으로 관찰되는 7개월의 진행 없는 생존 미만을 초과했다. 발표는 클리블랜드 클리닉 레너 의대의 미나 로부스 박사가 진행할 예정이다.

IN8bio (Nasdaq: INAB) a annoncé une prochaine présentation orale plénière lors de la 29e Réunion Annuelle de la Society for Neuro-Oncology (SNO) prévue pour novembre 2024. La présentation fournira des données de suivi prolongées de l'essai de Phase 1 de INB-200, leur thérapie par cellules T gamma-delta pour les glioblastomes récemment diagnostiqués.

Les données précédemment présentées lors de l'ASCO en juin 2024 ont montré que 92 % des patients évaluables ont dépassé la médiane de survie sans progression de 7 mois généralement observée avec le traitement standard. La présentation sera réalisée par la Dr Mina Lobbous du Cleveland Clinic Lerner College of Medicine.

IN8bio (Nasdaq: INAB) kündigte eine bevorstehende plenare mündliche Präsentation auf dem 29. Jahrestreffen der Society for Neuro-Oncology (SNO) im November 2024 an. Die Präsentation wird erweiterte Nachfalldaten aus der Phase-1-Studie von INB-200, ihrer Gamma-Delta-T-Zelltherapie für neu diagnostiziertes Glioblastom, bereitstellen.

Zuvor präsentierte Daten auf der ASCO im Juni 2024 zeigten, dass 92% der bewertbaren Patienten die mediane progressionsfreie Überlebenszeit von 7 Monaten, die typischerweise mit der Standardtherapie beobachtet wird, überschritten. Die Präsentation wird von Dr. Mina Lobbous vom Cleveland Clinic Lerner College of Medicine gehalten.

Positive
  • 92% of evaluable patients exceeded median progression-free survival compared to standard therapy
  • Selection for plenary presentation at major industry conference indicates significant clinical findings
Negative
  • None.

Insights

This upcoming presentation at SNO warrants attention but is not immediately market-moving. The key highlight is that 92% of evaluable patients exceeded the typical 7-month median progression-free survival seen with standard care, which was previously reported at ASCO in June. While promising for IN8bio's gamma-delta T cell therapy in glioblastoma treatment, this is essentially a preview of upcoming data presentation rather than new clinical results.

For a micro-cap company ($23.4M), positive clinical data could significantly impact valuation. However, investors should wait for the actual presentation on November 23rd for detailed efficacy data, durability metrics and safety profile before making investment decisions. The small market cap suggests high risk but also potential for substantial upside if the longer-term follow-up data confirms the preliminary positive results.

  • Plenary Oral Presentation at SNO will provide latest clinical trial results from the previously enrolled INB-200 studies of autologous gamma-delta T cells for newly diagnosed glioblastoma (GBM)

NEW YORK, Nov. 12, 2024 (GLOBE NEWSWIRE) -- IN8bio, Inc. (Nasdaq: INAB), a clinical-stage biopharmaceutical company developing innovative gamma-delta T cell therapies, today announced an upcoming plenary oral presentation at the 29th Annual Meeting and Education Day of the Society for Neuro-Oncology (SNO), being hosted November 21 – 24, 2024 in Houston, TX. IN8bio will provide longer-term follow-up and additional data demonstrating the activity of its DRI gamma-delta T cell approach in solid tumors from the Phase 1 trial of INB-200. In June 2024, preliminary clinical data were presented at the American Society of Clinical Oncology (ASCO) Annual Meeting, demonstrating that 92% of evaluable patients treated in the investigator-initiated trial exceeded the median progression-free survival of 7 months typically observed using standard-of-care therapy with concomitant temozolomide (TMZ).

Details for the SNO oral presentation are as follows:

Title: INB-200: Fully Enrolled Phase 1 Study of Gene-Modified Autologous Gamma-Delta (γδ) T Cells in Newly Diagnosed Glioblastoma Multiforme (GBM) Patients Receiving Maintenance Temozolomide (TMZ)

Presenter: Mina Lobbous, MD, MSPH, Assistant Professor, Cleveland Clinic Lerner College of Medicine
Abstract #: CTIM-09
Session Name: Abstract Session – Clinical Trials
Date and Time: Saturday, November 23, 2024, 11:25 AM - 11:35 AM CST

The abstract will be available online and can be accessed via the conference website at SNO 29th Annual Meeting & Education Day.

About IN8bio
IN8bio is a clinical-stage biopharmaceutical company developing gamma-delta T cell-based immunotherapies for cancer patients. Gamma-delta T cells are a specialized population of T cells that possess unique properties, including the ability to differentiate between healthy and diseased tissue. The company’s lead program, INB-100, is focused on evaluating haplo-matched allogenic gamma-delta T cells given to patients with AML following a hematopoietic stem cell transplant. The company is also evaluating autologous DeltEx DRI gamma-delta T cells, in combination with standard of care, for glioblastoma. For more information about IN8bio, visit www.IN8bio.com.

Investor & Company Contacts:
Glenn Schulman, PharmD, MPH
203.494.7411
gdschulman@in8bio.com
Patrick McCall
IN8bio, Inc.
646.933.5603
pfmccall@IN8bio.com

Media Contact:
Kimberly Ha
KKH Advisors
917.291.5744
kimberly.ha@kkhadvisors.com


FAQ

What are the latest clinical trial results for IN8bio's INB-200 (INAB stock)?

92% of evaluable patients treated with INB-200 exceeded the median progression-free survival of 7 months typically observed with standard-of-care therapy, as reported in June 2024 at ASCO.

When will IN8bio (INAB) present their INB-200 glioblastoma trial data at SNO 2024?

IN8bio will present the INB-200 trial data on Saturday, November 23, 2024, from 11:25 AM to 11:35 AM CST at the SNO Annual Meeting in Houston, TX.

What type of therapy is IN8bio's INB-200 (INAB)?

INB-200 is a gene-modified autologous gamma-delta T cell therapy being developed for newly diagnosed glioblastoma multiforme (GBM) patients receiving maintenance temozolomide.

IN8bio, Inc.

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