Welcome to our dedicated page for Immutep news (Ticker: IMMP), a resource for investors and traders seeking the latest updates and insights on Immutep stock.
Overview of Immutep Ltd
Immutep Ltd is a globally active biotechnology company committed to advancing immunotherapy for both cancer and autoimmune diseases. Leveraging its expertise in immuno-oncology and innovative LAG-3 technology, the company has positioned itself as a specialized entity in personalized bio-therapeutic products. With dual listings on the Australian Stock Exchange and Nasdaq, Immutep demonstrates a robust international presence and a solid foundation in research and development.
Core Technology and Therapeutic Approach
The hallmark of Immutep’s approach is its focus on the LAG-3 immune control mechanism, a critical regulator of the T cell immune response. By modulating this pathway, Immutep aims to enhance the body’s natural ability to fight cancer and potentially address autoimmune conditions. This technology underpins the company’s strategic pipeline and sets a high standard for clinical precision and targeted therapy development.
Product Pipeline and Clinical Development
Immutep’s product portfolio is centered around its most advanced candidate, IMP321, which functions as a T cell immunostimulatory factor. This therapy is designed for integration into cancer chemoimmunotherapy protocols and has achieved significant clinical milestones in early phase trials. In addition to IMP321, the company is developing IMP701, a blocking anti-LAG-3 antibody candidate in early clinical evaluation, and CVac, a personalized immunocellular strategy under investigation for epithelial cancers. These development efforts illustrate a diverse and forward-looking approach that integrates both innovation and strategic collaboration.
Global Operations and Strategic Collaborations
Operating primarily from Australia, Immutep extends its influence across global markets, supported by strong regulatory compliance and research proficiency. Strategic partnerships with large pharmaceutical firms reinforce its pipeline development, enabling access to advanced clinical platforms and shared expertise. The company’s qualification for significant research tax incentives in both Europe and Australia underscores its commitment to high-caliber R&D and validates the commercial and scientific merits of its initiatives.
Industry Position and Business Model
Within the competitive landscape of biotechnology, Immutep differentiates itself by combining deep scientific expertise with a focused therapeutic strategy. Its business model hinges on collaborative partnerships, clinical innovation, and a targeted approach to harnessing LAG-3 mediated immune modulation. Investors and industry observers appreciate the rigorous clinical frameworks employed by the company, which underpin its potential to offer novel therapeutic modalities in the area of cancer treatment and beyond.
Research and Development Excellence
Immutep’s strategic emphasis on research and development is reflected in its participation in international R&D incentive programs. These initiatives not only provide substantial financial support for its clinical trials but also affirm the company’s adherence to high industry standards and scientific integrity. This relentless focus on innovation is at the core of Immutep’s operational ethos, ensuring that its immunotherapeutic solutions are developed in a rigorous and transparent environment.
Conclusion
In summary, Immutep Ltd stands as a key player in the biotechnology industry, with a specific focus on immunotherapy modalities for cancer and autoimmune diseases. Its reliance on advanced LAG-3 technology, comprehensive product pipeline, and robust global partnerships collectively fortify its standing in the competitive landscape. The company’s commitment to R&D excellence and transparent clinical strategies provides a rich source of insight for those seeking to understand a pioneering approach in modern biotechnology.
Immutep Limited, a clinical-stage biotechnology company, announced participation in two investor conferences: the Cantor Fitzgerald's Oncology Conference on September 28, 2022, and the Ladenburg Thalmann Healthcare Conference on September 29, 2022. CEO Marc Voigt and COO Deanne Miller will discuss trends and challenges in immuno-oncology. A live webcast of the Ladenburg presentation will be available on Immutep's website. The company focuses on developing LAG-3 related immunotherapies for cancer and autoimmune diseases, aiming to provide innovative treatments.
Immutep (ASX: IMM; NASDAQ: IMMP) announced a €1,804,341 (~A$2,693,046) cash payment from the French Government under the Crédit d’Impôt Recherche (CIR) scheme. This R&D tax incentive supports eligible expenditure incurred during the 2021 calendar year for research in Europe. The funds will be allocated for the ongoing global clinical development of eftilagimod alpha and the preclinical development of IMP761. Immutep also qualifies for Australian R&D tax rebates, enhancing its financial position for future projects.
Immutep Limited (ASX: IMM; NASDAQ: IMMP) has provided an update on its eftilagimod alpha clinical trials, highlighting promising Phase II results in non-small cell lung cancer (NSCLC), head and neck squamous cell cancer (HNSCC), and metastatic breast cancer (MBC). The company is prioritizing 1L NSCLC for late-stage trials, with significant data expected in Q4 2022. Efti has shown strong clinical benefits especially in patients with low PD-L1 expression, suggesting a broad therapeutic potential. With approximately $80 million in cash, Immutep is funded for its expansion into early 2024.
Immutep Limited (NASDAQ: IMMP) appointed Professor Frédéric Triebel as Executive Director, enhancing its leadership team. Triebel, known for his groundbreaking work on the LAG-3 gene at Institut Gustave Roussy, has been pivotal in developing LAG-3-related therapies. His appointment aligns with Immutep’s commercialization strategy, focusing on their lead candidate, eftilagimod alpha, which shows promising clinical results and safety. With ongoing advancements and growing industry recognition, Immutep is well-positioned in the immunotherapy market.
Immutep Limited (ASX: IMM; NASDAQ: IMMP) announces the expansion of its efti clinical development pipeline with a new Phase II trial targeting soft tissue sarcoma. The study, funded by a €1.5M (approx. A$2.2M) grant from the Polish government, will assess efti in combination with pembrolizumab and radiotherapy in up to 40 patients. The first patient is expected to begin dosing by H1 2023, with initial data anticipated in Q4 2024. The trial is a collaboration with the Maria Skłodowska-Curie National Research Institute of Oncology, enhancing efti's potential in cancer treatment.
Immutep Limited (ASX: IMM; NASDAQ: IMMP) has announced the granting of a new patent by the Japanese Patent Office, enhancing its intellectual property portfolio for eftilagimod alpha (efti), a LAG-3 fusion protein. This patent protects therapeutic combinations of efti with anti-PD-(L)1 antibodies, alongside specific claims for various approved combinations. Following similar patents granted globally, this strengthens Immutep's position in the biotech sector. The patent will expire on January 8, 2036.
CEO Marc Voigt emphasized the significance of this development in conjunction with promising data from recent clinical trials.
Immutep Limited (NASDAQ: IMMP) announced promising interim results from the Phase II TACTI-002 trial for patients with 2nd line PD-X refractory non-small cell lung cancer (NSCLC). Key findings include a median overall survival of 9.7 months and a 36.5% survival rate at 18 months for patients receiving efti combined with pembrolizumab. The study, which involves 36 patients, shows favorable safety and tolerability compared to traditional chemotherapy. These results support the potential of efti as a viable treatment option for advanced NSCLC patients.
Immutep Limited (NASDAQ: IMMP) announced significant progress in its clinical trials for cancer therapies. The Phase II TACTI-002 trial demonstrated a 38.6% Overall Response Rate for efti in 1st line non-small cell lung cancer patients. Additionally, biomarker analysis from the Phase IIb AIPAC trial confirmed that efti activates the immune system, correlating with improved survival rates. The company remains well-funded, with approximately $80 million in cash, ensuring operational stability into early 2024. Four notable oncologists have joined the Clinical Advisory Board to enhance strategic direction.
Immutep Limited (ASX: IMM; NASDAQ: IMMP) has announced the grant of a new patent by the Japanese Patent Office for its pre-clinical candidate IMP761, targeting autoimmune diseases. The patent is valid until September 1, 2036, and follows a similar grant in Europe. CEO Marc Voigt highlighted the importance of protecting IMP761, which operates as a LAG-3 agonist, aiming to treat the underlying causes of autoimmune diseases. The company is collaborating with Northway Biotech for GMP compliant manufacturing ahead of clinical testing.
Immutep Limited (ASX: IMM; NASDAQ: IMMP) announced new data from the Phase II TACTI-002 trial focusing on non-small cell lung cancer (NSCLC) patients. This data will be presented at the IASLC 2022 World Conference on Lung Cancer in Vienna from August 6-9, 2022. The poster's abstract will be available on July 8, 2022. The TACTI-002 trial evaluates the combination of eftilagimod alpha and pembrolizumab in patients with second line PD-1/PD-L1 refractory metastatic NSCLC. Immutep is dedicated to developing innovative immunotherapy treatments for cancer and autoimmune diseases.
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