Immutep to Announce New TACTI-002 Data at the 2022 World Conference on Lung Cancer

Rhea-AI Summary

Immutep Limited (ASX: IMM; NASDAQ: IMMP) announced new data from the Phase II TACTI-002 trial focusing on non-small cell lung cancer (NSCLC) patients. This data will be presented at the IASLC 2022 World Conference on Lung Cancer in Vienna from August 6-9, 2022. The poster's abstract will be available on July 8, 2022. The TACTI-002 trial evaluates the combination of eftilagimod alpha and pembrolizumab in patients with second line PD-1/PD-L1 refractory metastatic NSCLC. Immutep is dedicated to developing innovative immunotherapy treatments for cancer and autoimmune diseases.

Positive

• Presentation of new data from the Phase II TACTI-002 trial could enhance Immutep's visibility and credibility in the oncology field.
• Partnership with Merck & Co. for the TACTI-002 trial may attract further interest and potential collaboration opportunities.

Negative

• None.

SYDNEY, AUSTRALIA, June 27, 2022 (GLOBE NEWSWIRE) -- Immutep Limited (ASX: IMM; NASDAQ: IMMP) ("Immutep” or “the Company”), a biotechnology company developing novel LAG-3-related immunotherapy treatments for cancer and autoimmune disease, announces new data from second line non-small cell lung cancer patients (Part B) in the Phase II TACTI-002 trial has been selected for a poster presentation at the IASLC 2022 World Conference on Lung Cancer (WCLC 2022) taking place in-person and online from 6-9 August 2022 in Vienna, Austria.

The abstract for the poster will be available from 6:00 pm EST on 8 July 2022 at wclc2022.iaslc.org and will subsequently be made available on Immutep’s website at www.immutep.com.

The poster presentation including an audio recording by TACTI-002 Principal Investigator, Prof Martin Forster, will also be made available after the poster presentation session (date below).

TACTI-002 Abstract
Title:  TACTI-002: A phase II study of eftilagimod alpha (soluble LAG-3) & pembrolizumab in 2nd line PD-1/PD-L1 refractory metastatic NSCLC
Session Title:  Metastatic Non-small Cell Lung Cancer – Immunotherapy
Session Number:  EP08.01
Presentation Session:  7-8 August 2022, 9:45 am – 6:00 pm CET
Presenting Author:  Martin Forster M.D., Ph.D., University College London
Control #:  82

About WCLC 2022
WCLC is the world's largest international gathering of clinicians, researchers and scientists in the field of lung cancer and thoracic oncology. It is held by the International Association for the Study of Lung Cancer (IASLC) which is a global network of more than 8,000 lung and thoracic cancer specialists from all disciplines dedicated to the study and eradication of lung cancer and other thoracic malignancies. Visit wclc2022.iaslc.org for more.

About TACTI-002
TACTI-002 (Two ACTive Immunotherapies) is a Phase II clinical trial being conducted in collaboration with Merck & Co., Inc., Rahway, NJ, USA (known as “MSD” outside the United States and Canada). The study is evaluating the combination of Immutep’s eftilagimod alpha with MSD’s KEYTRUDA® (pembrolizumab) in up to 189 patients with second line head and neck squamous cell carcinoma (HNSCC) or non-small cell lung cancer (NSCLC) in first and second line.

About Immutep
Immutep is a globally active biotechnology company that is a leader in the development of LAG-3 related immunotherapeutic products for the treatment of cancer and autoimmune disease. Immutep is dedicated to leveraging its technology and expertise to bring innovative treatment options to market for patients and to maximize value to shareholders. Immutep is listed on the Australian Securities Exchange (IMM), and on the NASDAQ (IMMP) in the United States.

Immutep’s current lead product candidate is eftilagimod alpha (“efti” or “IMP321”), a soluble LAG-3 fusion protein (LAG-3Ig), which is a first-in-class antigen presenting cell (APC) activator being explored in cancer and infectious disease. Immutep is also developing an agonist of LAG-3 (IMP761) for autoimmune disease. Additional LAG-3 products, including antibodies for immune response modulation, are being developed by Immutep’s large pharmaceutical partners.

Further information can be found on the Company’s website www.immutep.com or by contacting:

Australian Investors/Media:
Catherine Strong, Citadel-MAGNUS
+61 (0)406 759 268; cstrong@citadelmagnus.com

U.S. Media:
Tim McCarthy, LifeSci Advisors
+1 (212) 915.2564; tim@lifesciadvisors.com

FAQ

What is the TACTI-002 trial by Immutep?

The TACTI-002 trial is a Phase II clinical study evaluating the combination of Immutep's eftilagimod alpha and Merck's pembrolizumab in patients with second line non-small cell lung cancer.

Where will the new data from the TACTI-002 trial be presented?

The new data will be presented at the IASLC 2022 World Conference on Lung Cancer in Vienna from August 6-9, 2022.

When will the abstract for the TACTI-002 trial be available?

The abstract will be available on July 8, 2022, at 6:00 pm EST.

What are the main objectives of the TACTI-002 trial?

The main objective is to evaluate the efficacy and safety of the combination treatment in patients with PD-1/PD-L1 refractory metastatic non-small cell lung cancer.

What is the stock symbol for Immutep?

Immutep is listed on the ASX under the ticker IMM and on NASDAQ with the ticker IMMP.