Illumina Reports Financial Results for Fourth Quarter and Fiscal Year 2020

Rhea-AI Summary

Illumina reported record fourth-quarter revenue of $953 million, a 20% increase from Q3 2020 and slightly higher than 2019. GAAP net income for the quarter was $257 million ($1.75/share), up from $239 million ($1.61/share) year-over-year. However, non-GAAP net income decreased to $179 million ($1.22/share) from $252 million ($1.70/share). Full-year revenue dropped 9% to $3,239 million, and GAAP net income fell to $656 million from $1,002 million in 2019. The company projects 2021 revenue growth of 17% to 20% and earnings per share of $4.76 to $5.01.

Positive

• Record fourth-quarter revenue of $953 million, up 20% from Q3 2020.
• GAAP net income increased to $257 million ($1.75/share) from $239 million ($1.61/share) in Q4 2019.
• Record orders in the quarter, including for sequencing instruments.
• Cash flow from operations reached $406 million.

Negative

• Non-GAAP net income dropped to $179 million ($1.22/share) from $252 million ($1.70/share) year-over-year.
• Full-year revenue decreased 9% compared to 2019.
• Gross margin declined to 66.1% from 69.5% in Q4 2019.

Illumina, Inc. (NASDAQ: ILMN) today announced its financial results for the fourth quarter and fiscal year 2020.

Record fourth quarter revenue reflects a strong close to 2020:

• Revenue of $953 million, an increase of 20% compared to the third quarter of 2020 and $0.5 million higher compared to the prior year period
• GAAP net income attributable to Illumina stockholders for the quarter of $257 million, or $1.75 per diluted share, compared to $239 million, or $1.61 per diluted share, for the prior year period
• Non-GAAP net income attributable to Illumina stockholders for the quarter of $179 million, or $1.22 per diluted share, compared to $252 million, or $1.70 per diluted share, for the prior year period. Non-GAAP net income excludes net gains from mark-to-market adjustments on our strategic investments, primarily from our marketable equity securities (see the “Reconciliation Between GAAP and Non-GAAP Net Income Attributable to Illumina Stockholders” table for a reconciliation of these GAAP and non-GAAP financial measures)
• Cash flow from operations of $406 million compared to $443 million in the prior year period
• Free cash flow (cash flow from operations less capital expenditures) of $344 million for the quarter compared to $386 million in the prior year period

“Illumina delivered a strong finish to 2020 with record fourth quarter revenue exceeding our expectations,” said Francis deSouza, Chief Executive Officer. “We also had record orders in the quarter, including record sequencing instrument orders and the second highest quarter for NovaSeq instrument orders. Our business delivered strong sequential growth in the second half of 2020 and we expect continued recovery from the pandemic in 2021.”

Gross margin in the fourth quarter of 2020 was 66.1% compared to 69.5% in the prior year period. Excluding amortization of acquired intangible assets and expenses related to COVID-19, non-GAAP gross margin was 66.9% for the fourth quarter of 2020 compared to 70.2% in the prior year period.

Research and development (R&D) expenses for the fourth quarter of 2020 were $200 million compared to $161 million in the prior year period. Non-GAAP R&D expenses as a percentage of revenue were 20.9% compared to 16.8% in the prior year period.

Selling, general and administrative (SG&A) expenses for the fourth quarter of 2020 were $298 million compared to $233 million in the prior year period. Excluding acquisition-related expenses, expenses related to COVID-19, and gain on litigation, non-GAAP SG&A expenses as a percentage of revenue were 25.1% compared to 22.2% in the prior year period.

Depreciation and amortization expenses were $50 million and capital expenditures for free cash flow purposes were $62 million during the fourth quarter of 2020. At the close of the quarter, the company held $3.5 billion in cash, cash equivalents and short-term investments, compared to $3.4 billion as of December 29, 2019.

Fiscal year 2020 results:

• Revenue of $3,239 million, a 9% decrease compared to $3,543 million in fiscal 2019
• GAAP net income attributable to Illumina stockholders of $656 million, or $4.45 per diluted share, compared to $1,002 million, or $6.74 per diluted share, in fiscal 2019
• Non-GAAP net income attributable to Illumina stockholders of $664 million, or $4.50 per diluted share, compared to $976 million, or $6.57 per diluted share, in fiscal 2019 (see the “Itemized Reconciliation Between GAAP and Non-GAAP Net Income Attributable to Illumina Stockholders” table for a reconciliation of these GAAP and non-GAAP financial measures)
• Cash flow from operations of $1,080 million compared to $1,051 million in fiscal 2019
• Free cash flow (cash flow from operations less capital expenditures) of $891 million, compared to $842 million in fiscal 2019

Gross margin for fiscal 2020 was 68.0% compared to 69.6% in the prior year. Excluding amortization of acquired intangible assets, expenses and income related to COVID-19, and restructuring, non-GAAP gross margin was 69.0% for fiscal 2020 compared to 70.6% in the prior year period.

R&D expenses for fiscal 2020 were $682 million compared to $647 million in the prior year. Excluding expenses and income related to COVID-19, non-GAAP R&D expenses as a percentage of revenue were 21.0% compared to 18.2% in the prior year period.

SG&A expenses for fiscal 2020 were $941 million compared to $835 million in the prior year period. Excluding amortization of acquired intangible assets, acquisition-related expenses, expenses and income related to COVID-19, gain on litigation, and restructuring, non-GAAP SG&A expenses as a percentage of revenue were 24.6% compared to 22.0% in the prior year period.

Updates since our last earnings release:

• Expanded NextSeq 2000 flow cell offering with launch of the P3 Reagent Kit and started shipping the NextSeq 1000
• Announced TSO 500 partnerships with Bristol Myers Squibb, Kura Oncology, Myriad Genetics, and Merck to advance comprehensive genomic profiling
• Launched Illumina Connected Analytics enabling customers to manage, analyze, and explore large volumes of multi-omic data in a secure, scalable, and flexible environment
• Partnered with Harvard Pilgrim Health Care to expand access to whole-genome sequencing for genetic disease testing
• Won patent infringement suit against BGI in the United Kingdom
• Repurchased approximately $280 million of common stock in the fourth quarter with $15 million remaining for repurchase under our current plan
• Announced a collaboration with Sequoia Capital China to catalyze the genomic startup ecosystem in China

Financial outlook and guidance

The non-GAAP financial guidance discussed below reflects certain pro forma adjustments to assist in analyzing and assessing our core operational performance. Please see our Reconciliation of Non-GAAP Financial Guidance included in this release for a reconciliation of the GAAP and non-GAAP financial measures.

For fiscal 2021, the company expects year-over-year revenue growth in the range of 17% to 20%, and expects GAAP earnings per diluted share of $4.76 to $5.01 and non-GAAP earnings per diluted share of $5.10 to $5.35. This guidance excludes the potential impact from the pending acquisition of GRAIL, which we expect to close in the second half of 2021.

Quarterly conference call information

The conference call will begin at 2:00 pm Pacific Time (5:00 pm Eastern Time) on Thursday, February 11, 2021. Interested parties may access the live teleconference through the Investor Info section of Illumina’s website under the “Company” tab at www.illumina.com. Alternatively, individuals can access the call by dialing 1 (866) 211-4597 or 1 (647) 689-6853 outside North America, both with conference ID 3809129.

A replay of the conference call will be posted on Illumina’s website after the event and will be available for at least 30 days following.

Statement regarding use of non-GAAP financial measures

The company reports non-GAAP results for diluted net income per share, net income, gross margins, operating expenses, operating margins, other income, and free cash flow in addition to, and not as a substitute for, or superior to, financial measures calculated in accordance with GAAP. The company’s financial measures under GAAP include substantial charges such as amortization of acquired intangible assets, non-cash interest expense associated with the company’s convertible debt instruments that may be settled in cash, and others that are listed in the itemized reconciliations between GAAP and non-GAAP financial measures included in this press release. Management has excluded the effects of these items in non-GAAP measures to assist investors in analyzing and assessing past and future operating performance. Additionally, non-GAAP net income attributable to Illumina stockholders and diluted earnings per share attributable to Illumina stockholders are key components of the financial metrics utilized by the company’s board of directors to measure, in part, management’s performance and determine significant elements of management’s compensation.

The company encourages investors to carefully consider its results under GAAP, as well as its supplemental non-GAAP information and the reconciliation between these presentations, to more fully understand its business. Reconciliations between GAAP and non-GAAP results are presented in the tables of this release.

Use of forward-looking statements

This release may contain forward-looking statements that involve risks and uncertainties. Among the important factors to which our business is subject that could cause actual results to differ materially from those in any forward-looking statements are: (i) the impact to our business and operating results of the COVID-19 pandemic; (ii) changes in the rate of growth in the markets we serve; (iii) the volume, timing and mix of customer orders among our products and services; (iv) our ability to adjust our operating expenses to align with our revenue expectations; (v) the outcome of the pending acquisition of GRAIL, Inc.; (vi) our ability to manufacture robust instrumentation and consumables; (vii) the success of products and services competitive with our own; (viii) challenges inherent in developing, manufacturing, and launching new products and services, including expanding or modifying manufacturing operations and reliance on third-party suppliers for critical components; (ix) the impact of recently launched or pre-announced products and services on existing products and services; (x) our ability to further develop and commercialize our instruments and consumables, to deploy new products, services, and applications, and to expand the markets for our technology platforms; (xi) our ability to obtain regulatory clearance for our products from government agencies; (xii) our ability to successfully partner with other companies and organizations to develop new products, expand markets, and grow our business; (xiii) our ability to successfully identify and integrate acquired technologies, products, or businesses; and (xiv) the application of generally accepted accounting principles, which are highly complex and involve many subjective assumptions, estimates, and judgments, together with other factors detailed in our filings with the Securities and Exchange Commission, including our most recent filings on Forms 10-K and 10-Q, or in information disclosed in public conference calls, the date and time of which are released beforehand. We undertake no obligation, and do not intend, to update these forward-looking statements, to review or confirm analysts’ expectations, or to provide interim reports or updates on the progress of the current quarter.

About Illumina

Illumina is improving human health by unlocking the power of the genome. Our focus on innovation has established us as the global leader in DNA sequencing and array-based technologies, serving customers in the research, clinical and applied markets. Our products are used for applications in the life sciences, oncology, reproductive health, agriculture and other emerging segments. To learn more, visit www.illumina.com and connect with us on Twitter, Facebook, LinkedIn, Instagram, and YouTube.

Illumina, Inc. Condensed Consolidated Balance Sheets (In millions)
		January 3, 2021				December 29, 2019
ASSETS		(unaudited)
Current assets:
Cash and cash equivalents		$	1,810			$	2,042
Short-term investments		1,662				1,372
Accounts receivable, net		487				573
Inventory		372				359
Prepaid expenses and other current assets		152				105
Total current assets		4,483				4,451
Property and equipment, net		922				889
Operating lease right-of-use assets		532				555
Goodwill		897				824
Intangible assets, net		142				145
Deferred tax assets, net		20				64
Other assets		589				388
Total assets		$	7,585			$	7,316
LIABILITIES AND STOCKHOLDERS’ EQUITY
Current liabilities:
Accounts payable		$	192			$	149
Accrued liabilities		541				516
Long-term debt, current portion		511				—
Total current liabilities		1,244				665
Operating lease liabilities		671				695
Long-term debt		673				1,141
Other long-term liabilities		303				202
Stockholders’ equity		4,694				4,613
Total liabilities and stockholders’ equity		$	7,585			$	7,316

Illumina, Inc. Condensed Consolidated Statements of Income (In millions, except per share amounts) (unaudited)
		Three Months Ended								Year Ended
		January 3, 2021				December 29, 2019				January 3, 2021				December 29, 2019
Revenue:
Product revenue		$	831			$	812			$	2,735			$	2,929
Service and other revenue		122				141				504				614
Total revenue		953				953				3,239				3,543
Cost of revenue:
Cost of product revenue (a)		254				230				788				802
Cost of service and other revenue (a)		62				55				220				240
Amortization of acquired intangible assets		7				6				28				34
Total cost of revenue		323				291				1,036				1,076
Gross profit		630				662				2,203				2,467
Operating expense:
Research and development (a)		200				161				682				647
Selling, general and administrative (a)		298				233				941				835
Total operating expense		498				394				1,623				1,482
Income from operations		132				268				580				985
Other income, net		166				1				276				133
Income before income taxes		298				269				856				1,118
Provision for income taxes		41				30				200				128
Consolidated net income		257				239				656				990
Add: Net loss attributable to noncontrolling interests		—				—				—				12
Net income attributable to Illumina stockholders		$	257			$	239			$	656			$	1,002
Earnings per share attributable to Illumina stockholders:
Basic		$	1.76			$	1.63			$	4.48			$	6.81
Diluted		$	1.75			$	1.61			$	4.45			$	6.74
Shares used in computing earnings per common share:
Basic		146				147				147				147
Diluted		147				148				148				149

(a) Includes stock-based compensation expense for stock-based awards:

		Three Months Ended								Year Ended
		January 3, 2021				December 29, 2019				January 3, 2021				December 29, 2019
Cost of product revenue		$	8			$	5			$	21			$	19
Cost of service and other revenue		1				1				4				4
Research and development		26				16				74				66
Selling, general and administrative		44				28				95				105
Stock-based compensation expense before taxes (1)		$	79			$	50			$	194			$	194

(1) Includes stock-based compensation of $1.5 million for Helix in fiscal year 2019.

Illumina, Inc. Condensed Consolidated Statements of Cash Flows (In millions) (unaudited)
		Three Months Ended										Year Ended
		January 3, 2021					December 29, 2019					January 3, 2021					December 29, 2019
Net cash provided by operating activities		$	406				$	443				$	1,080				$	1,051
Net cash (used in) provided by investing activities		(33		)			(104		)			(554		)			745
Net cash used in financing activities		(331		)			(115		)			(766		)			(897		)
Effect of exchange rate changes on cash and cash equivalents		7					3					8					(1		)
Net increase (decrease) in cash and cash equivalents		49					227					(232		)			898
Cash and cash equivalents, beginning of period		1,761					1,815					2,042					1,144
Cash and cash equivalents, end of period		$	1,810				$	2,042				$	1,810				$	2,042
Calculation of free cash flow:
Net cash provided by operating activities (b)		$	406				$	443				$	1,080				$	1,051
Purchases of property and equipment		(62		)			(57		)			(189		)			(209		)
Free cash flow (a)		$	344				$	386				$	891				$	842

(a) Free cash flow, which is a non-GAAP financial measure, is calculated as net cash provided by operating activities reduced by purchases of property and equipment. Free cash flow is useful to management as it is one of the metrics used to evaluate our performance and to compare us with other companies in our industry. However, our calculation of free cash flow may not be comparable to similar measures used by other companies.
(b) Net cash provided by operating activities in fiscal 2019 included an $84 million payment of the accreted debt discount related to the conversions of our 2019 Notes.

Illumina, Inc. Results of Operations - Non-GAAP (In millions, except per share amounts) (unaudited) RECONCILIATION BETWEEN GAAP AND NON-GAAP EARNINGS PER SHARE ATTRIBUTABLE TO ILLUMINA STOCKHOLDERS:
		Three Months Ended										Year Ended
		January 3, 2021					December 29, 2019					January 3, 2021					December 29, 2019
GAAP earnings per share attributable to Illumina stockholders - diluted		$	1.75				$	1.61				$	4.45				$	6.74
Cost of revenue (b)		0.05					0.04					0.21					0.23
Research and development costs (b)		—					0.01					0.01					0.02
Selling, general and administrative costs (b)		0.40					0.14					0.98					0.36
Other (income) expense, net (b)		(0.99		)			0.08					(1.60		)			(0.47		)
Incremental non-GAAP tax expense (c)		0.07					(0.09		)			0.02					(0.11		)
Income tax benefit (d)		(0.06		)			(0.09		)			(0.18		)			(0.20		)
Tax expense related to increase in valuation allowance (e)		—					—					0.42					—
Tax expense related to cost-sharing arrangement (f)		—					—					0.19					—
Non-GAAP earnings per share attributable to Illumina stockholders - diluted (a)		$	1.22				$	1.70				$	4.50				$	6.57

RECONCILIATION BETWEEN GAAP AND NON-GAAP NET INCOME ATTRIBUTABLE TO ILLUMINA STOCKHOLDERS:
		Three Months Ended										Year Ended
		January 3, 2021					December 29, 2019					January 3, 2021					December 29, 2019
GAAP net income attributable to Illumina stockholders		$	257				$	239				$	656				$	1,002
Cost of revenue (b)		8					6					32					34
Research and development costs (b)		—					1					1					3
Selling, general and administrative costs (b)		59					21					145					54
Other (income) expense, net (b)		(146		)			13					(236		)			(70		)
Incremental non-GAAP tax expense (c)		10					(14		)			3					(16		)
Income tax benefit (d)		(9		)			(14		)			(27		)			(31		)
Tax expense related to increase in valuation allowance (e)		—					—					62					—
Tax expense related to cost-sharing arrangement (f)		—					—					28					—
Non-GAAP net income attributable to Illumina stockholders (a)		$	179				$	252				$	664				$	976

All amounts in tables are rounded to the nearest millions, except as otherwise noted. As a result, certain amounts may not recalculate using the rounded amounts provided.

(a) Non-GAAP net income attributable to Illumina stockholders and diluted earnings per share attributable to Illumina stockholders exclude the effect of the pro forma adjustments as detailed above. Non-GAAP net income attributable to Illumina stockholders and diluted earnings per share attributable to Illumina stockholders are key components of the financial metrics utilized by the company’s board of directors to measure, in part, management’s performance and determine significant elements of management’s compensation. Management has excluded the effects of these items in these measures to assist investors in analyzing and assessing our past and future core operating performance.
(b) Refer to our “Itemized Reconciliation between GAAP and Non-GAAP Results of Operations as a Percent of Revenue,” below, for the components of these amounts.
(c) Incremental non-GAAP tax expense reflects the tax impact of the non-GAAP adjustments listed.
(d) Amounts represent tax deductions taken in excess of stock compensation cost.
(e) Amount represents tax expense related to the valuation allowance established against the deferred tax asset for California research and development credits.
(f) Amount represents tax expense related to the finalization of the Altera court case which determined stock-based compensation must be included in intercompany cost sharing payments.

Illumina, Inc. Results of Operations - Non-GAAP (continued) (Dollars in millions) (unaudited) ITEMIZED RECONCILIATION BETWEEN GAAP AND NON-GAAP RESULTS OF OPERATIONS AS A PERCENT OF REVENUE:
		Three Months Ended																Year Ended
		January 3, 2021								December 29, 2019								January 3, 2021								December 29, 2019
GAAP gross profit (b)		$	630			66.1		%		$	662			69.5		%		$	2,203			68.0		%		$	2,467			69.6		%
Amortization of acquired intangible assets		7				0.7		%		6				0.7		%		28				0.9		%		34				1.0		%
Expenses related to COVID-19 (c)		1				0.1		%		—				—				6				0.2		%		—				—
Income related to COVID-19 (d)		—				—				—				—				(4		)		(0.1	)	%		—				—
Restructuring (e)		—				—				—				—				2				—				—				—
Non-GAAP gross profit (a)		$	638			66.9		%		$	668			70.2		%		$	2,235			69.0		%		$	2,501			70.6		%
GAAP research and development expense		$	200			20.9		%		$	161			16.9		%		$	682			21.1		%		$	647			18.3		%
Expenses related to COVID-19 (c)		—				—				—				—				(4		)		(0.1	)	%		—				—
Income related to COVID-19 (d)		—				—				—				—				3				—				—				—
Restructuring (e)		—				—				(1		)		(0.1	)	%		—				—				(3		)		(0.1	)	%
Non-GAAP research and development expense		$	200			20.9		%		$	160			16.8		%		$	681			21.0		%		$	644			18.2		%
GAAP selling, general and administrative expense		$	298			31.2		%		$	233			24.4		%		$	941			29.0		%		$	835			23.5		%
Amortization of acquired intangible assets		—				—				(1		)		(0.1	)	%		(1		)		—				(2		)		—
Acquisition-related expenses (f)		(52		)		(5.4	)	%		(12		)		(1.3	)	%		(158		)		(4.8	)	%		(43		)		(1.2	)	%
Expenses related to COVID-19 (c)		(9		)		(0.9	)	%		—				—				(18		)		(0.5	)	%		—				—
Gain on litigation (g)		2				0.2		%		—				—				27				0.9		%		—				—
Income related to COVID-19 (d)		—				—				—				—				3				—				—				—
Restructuring (e)		—				—				(8		)		(0.8	)	%		2				—				(9		)		(0.3	)	%
Non-GAAP selling, general and administrative expense		$	239			25.1		%		$	212			22.2		%		$	796			24.6		%		$	781			22.0		%
GAAP operating profit		$	132			13.9		%		$	268			28.1		%		$	580			17.9		%		$	985			27.8		%
Cost of revenue		8				0.9		%		6				0.7		%		32				1.0		%		34				1.0		%
Research and development costs		—				—				1				0.1		%		1				—				3				0.1		%
Selling, general and administrative costs		59				6.1		%		21				2.1		%		145				4.5		%		54				1.5		%
Non-GAAP operating profit (a)		$	199			20.9		%		$	296			31.0		%		$	758			23.4		%		$	1,076			30.4		%
GAAP other income, net		$	166			17.4		%		$	1			0.1		%		$	276			8.5		%		$	133			3.8		%
Non-cash interest expense (h)		12				1.3		%		11				1.2		%		43				1.3		%		49				1.4		%
Strategic investment related (gain) loss, net (i)		(159		)		(16.7	)	%		2				0.1		%		(300		)		(9.2	)	%		(66		)		(1.9	)	%
Loss on derivative assets (j)		—				—				—				—				25				0.8		%		—				—
Bridge facility fees (k)		3				0.3		%		—				—				3				—				—				—
(Gain) loss on contingent value right (l)		(2		)		(0.2	)	%		—				—				(7		)		(0.2	)	%		1				—
Gains on deconsolidation (m)		—				—				—				—				—				—				(54		)		(1.5	)	%
Non-GAAP other income, net (a)		$	20			2.1		%		$	14			1.4		%		$	40			1.2		%		$	63			1.8		%

All amounts in tables are rounded to the nearest millions, except as otherwise noted. As a result, certain amounts may not recalculate using the rounded amounts provided.

(a) Non-GAAP gross profit, included within non-GAAP operating profit, is a key measure of the effectiveness and efficiency of manufacturing processes, product mix and the average selling prices of our products and services. Non-GAAP operating profit, and non-GAAP other income, net, exclude the effects of the pro forma adjustments as detailed above. Management has excluded the effects of these items in these measures to assist investors in analyzing and assessing past and future operating performance.
(b) Reconciling amounts are recorded in cost of revenue.
(c) Amounts consist of direct and incremental expenses incurred due to the COVID-19 pandemic, primarily a one-time allowance paid to employees working remotely to help with additional expenses, write-off of unused COVID-19 lab equipment, premium pay for onsite essential workers, employee testing, incremental cleaning, and personal protective equipment.
(d) Amounts consist of direct and incremental income due to the COVID-19 pandemic, primarily payroll-related credits earned in Singapore.
(e) Amounts consist primarily of employee costs, net of adjustments, related to restructuring.
(f) Amount for Q4 2020 consists primarily of acquisition-related expenses related to the pending acquisition of GRAIL. Amount for fiscal year 2020 consists primarily of expenses related to the Continuation Advances and Reverse Termination Fee paid to Pacific Biosciences and expenses related to the pending acquisition of GRAIL. Amounts for Q4 and fiscal year 2019 consist primarily of expenses related to the Pacific Biosciences acquisition which was terminated on January 2, 2020.
(g) Amount consists of a gain related to a patent litigation judgement.
(h) Non-cash interest expense is calculated in accordance with the authoritative accounting guidance for convertible debt instruments that may be settled in cash.
(i) Amounts consist primarily of mark-to-market adjustments and impairments from our strategic investments.
(j) Amounts consist of fair value adjustments on our derivative assets related to the terminated acquisition with Pacific Biosciences.
(k) Amounts consist of expenses related to the bridge facility commitment obtained in advance of the acquisition of GRAIL.
(l) Amounts consist of fair value adjustments related to our contingent value right received from Helix.
(m) Amount consists of the $39 million gain recognized as a result of the Helix deconsolidation and a $15 million gain that resulted from the settlement of a contingency related to the deconsolidation of GRAIL in 2017.

Illumina, Inc.
Reconciliation of Non-GAAP Financial Guidance
(unaudited)

Our future performance and financial results are subject to risks and uncertainties, and actual results could differ materially from the guidance set forth below. Some of the factors that could affect our financial results are stated above in this press release. More information on potential factors that could affect our financial results is included from time to time in the public reports filed with the Securities and Exchange Commission, including Form 10-K for the fiscal year ended December 29, 2019 filed with the SEC on February 10, 2020, Form 10-Q for the fiscal quarter ended March 29, 2020, Form 10-Q for the fiscal quarter ended June 28, 2020, and Form 10-Q for the fiscal quarter ended September 27, 2020. We assume no obligation to update any forward-looking statements or information.

		Fiscal Year 2021
GAAP diluted earnings per share (a)		$4.76 - $5.01
Amortization of acquired intangible assets		0.18
Non-cash interest expense (b)		0.24
Incremental non-GAAP tax expense (c)		(0.08)
Non-GAAP diluted earnings per share (a)		$5.10 - $5.35

(a) Guidance excludes the potential impact of the pending acquisition of GRAIL, which is expected to close in the second half of 2021.
(b) Non-cash interest expense is calculated in accordance with the authoritative accounting guidance for convertible debt instruments that may be settled in cash.
(c) Incremental non-GAAP tax expense reflects the tax impact related to the non-GAAP adjustments listed.

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FAQ

What were Illumina's fourth-quarter revenue results for 2020?

Illumina reported fourth-quarter revenue of $953 million, a 20% increase from the previous quarter.

How did Illumina's net income change in Q4 2020 compared to Q4 2019?

GAAP net income increased to $257 million in Q4 2020 from $239 million in Q4 2019, but non-GAAP net income decreased to $179 million from $252 million.

What is Illumina's financial outlook for 2021?

Illumina expects 2021 revenue growth of 17% to 20% and GAAP earnings per diluted share between $4.76 and $5.01.

What were Illumina's full-year revenue results for 2020?

For fiscal year 2020, Illumina reported revenue of $3,239 million, a 9% decrease compared to $3,543 million in fiscal 2019.