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Gain Therapeutics, Inc. - GANX STOCK NEWS

Welcome to our dedicated page for Gain Therapeutics news (Ticker: GANX), a resource for investors and traders seeking the latest updates and insights on Gain Therapeutics stock.

Gain Therapeutics, Inc. (NASDAQ: GANX) is a pioneering biotechnology company committed to the discovery and development of novel small molecule therapeutics. Specializing in addressing rare genetic diseases, Gain Therapeutics focuses on orphan diseases caused by inborn errors of metabolism. With a strong emphasis on lysosomal storage disorders, central nervous system disorders, metabolic disorders, and oncology, the company's innovative approach aims to provide solutions where there is a high unmet medical need.

At the forefront of Gain Therapeutics' pipeline is GT-02287, a promising clinical-stage product candidate targeting GBA1 Parkinson's disease. Currently in Phase 1 clinical trials, GT-02287 is designed to be a disease-modifying treatment. It functions as an allosteric protein modulator to restore the activity of the lysosomal enzyme glucocerebrosidase (GCase), tackling the underlying cause of disease rather than just alleviating symptoms.

The company's proprietary Magellan™ platform leverages AI-supported structural biology and advanced algorithms to discover novel allosteric binding sites on disease-implicated proteins. This innovative computational technology identifies potential small molecules that can bind to these sites, offering new avenues for therapeutic development. Magellan builds upon Gain’s original SEE-Tx® platform, enhancing it with AI and virtual screening capabilities to explore vast chemical spaces.

Recent achievements highlight Gain Therapeutics' impact on the biotech landscape. Data presented at the 20th WORLDSymposium™ showcased the progressive reversal of motor deficits in preclinical models, alongside a significant reduction of neurodegeneration biomarkers. This underscores the potential of GT-02287 as a best-in-class treatment for neurodegenerative diseases.

Gain Therapeutics collaborates with notable organizations including The Michael J. Fox Foundation for Parkinson’s Research and The Silverstein Foundation for Parkinson’s with GBA. These partnerships provide essential support and validation for the company's mission to transform therapeutic landscapes with innovative treatments.

For more information, visit GainTherapeutics.com and follow their updates on LinkedIn.

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Gain Therapeutics (Nasdaq: GANX) held its inaugural R&D day webinar, highlighting its advancements in drug discovery through the SEE-Tx platform. The company focuses on developing treatments for GBA1 Parkinson's and Gaucher diseases, alongside other lysosomal storage disorders and metabolic diseases. Key 2022 priorities include initiating a Phase 1 trial for GBA1 Parkinson's and advancing its Gaucher disease program. Their innovative approach leverages new computational methods to identify allosteric targets and accelerate drug discovery.

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Gain Therapeutics (Nasdaq: GANX) announced its upcoming R&D Day on February 4, 2022, focusing on utilizing computational technology for allosteric drug discovery. The event will feature expert presentations discussing advancements in targeting undruggable proteins, including key topics on neurodegenerative diseases and oncology. Gain's proprietary SEE-Tx® Platform aims to transform drug discovery by identifying novel allosteric targets. The event is expected to shed light on Gain's pipeline and recent research data relevant to treatments for conditions like Parkinson's and Gaucher Disease.

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Gain Therapeutics (Nasdaq: GANX), a biotechnology company, has announced an upcoming R&D Day Event and participation in significant scientific conferences addressing neurodegenerative diseases. The R&D Day, titled "Neuroscience and Beyond: Harnessing Computational Technology and Allosteric Modulators to Drug the Undruggable", is scheduled for February 4, 2022, at 10:00 a.m. ET. Additionally, Gain will be present at the 18th Annual WORLDSymposium from February 7-11, 2022, and the AD/PD™ 2022 Conference from March 15-20, 2022.

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Gain Therapeutics, Inc. (Nasdaq: GANX) announced CEO Eric Richman will participate in the H.C. Wainwright BioConnect Conference from January 10-13, 2022. This virtual event will enable investor access via webcast, available for 90 days post-event. Gain Therapeutics focuses on innovative drug discovery, particularly targeting allosteric binding sites related to neurodegenerative diseases and lysosomal storage disorders. Supported by notable foundations and programs, the company aims to provide new treatment options for challenging disorders linked to protein misfolding.

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Gain Therapeutics, Inc. (Nasdaq: GANX) granted Chief Operating Officer Matthias Alder an option to purchase 200,000 shares and 200,000 restricted stock units. These incentives, part of the 2021 Inducement Equity Incentive Plan, aim to motivate Alder upon joining the company. The options will vest over four years, with a $5.86 exercise price per share, matching the closing stock price on December 22, 2021. The restricted units' vesting is contingent on business and clinical milestones. Gain focuses on innovative treatments for neurodegenerative diseases.

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Gain Therapeutics (Nasdaq: GANX) provided a scientific update on its Krabbe disease program, highlighting statistically significant increases in the GALC enzyme and a reduction in toxic substrate psychosine. This breakthrough suggests potential treatment options for patients with Krabbe disease, a severe genetic disorder affecting the nervous system. Initial tests on compounds showed promise in reducing psychosine levels. The next phase involves further evaluation of compounds in complex in vitro models.

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Gain Therapeutics, Inc. (Nasdaq: GANX) will present a corporate overview at the Imagine AI + Healthcare Investor Summit on December 7, 2021. CEO Eric Richman and Chief Scientific Officer Xavier Barril, Ph.D., will discuss Gain's innovative approach to targeting allosteric binding sites for neurodegenerative diseases and lysosomal storage disorders. The summit is an opportunity for investors to engage with various companies and learn about advancements in AI within healthcare.

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Gain Therapeutics (NASDAQ: GANX) reported its Q3 2021 financial results and announced key corporate developments. The company has $40.98 million in cash, providing a strong financial runway into the second half of 2023. Significant progress was made in patient-derived iPSC studies, showing STAR compounds positively affecting Gaucher and Parkinson's disease markers. Matthias Alder was appointed COO, and a five-member Scientific Advisory Board was established to advance the company’s clinical programs. Q3 revenues increased to $27 thousand, while net loss rose to $4.66 million, reflecting higher R&D and administrative expenses.

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Gain Therapeutics (Nasdaq: GANX) presented promising preclinical data on GT-02287, a compound targeting glucocerebrosidase (GCase) for Parkinson’s Disease, at the Society for Neuroscience Annual Meeting. The findings revealed that GT-02287 significantly reduced alpha-synuclein pathology and neuroinflammation while improving behavioral deficits in an animal model. With a favorable toxicity profile, this orally bioavailable compound shows potential in addressing unmet needs for patients suffering from Parkinson’s, particularly those with GBA1 mutations.

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Gain Therapeutics (Nasdaq: GANX) announced breakthrough results from a study on its STAR compounds, GT-02287 and GT-02329, for treating Gaucher and GBA1 Parkinson's Disease. Conducted at the University of Maryland, the study demonstrated significant increases in GCase protein levels in iPSC-derived dopaminergic neurons and reductions in phosphorylated α-synuclein. These findings reveal a potential new approach for neurodegenerative disorders, showing a 129% increase in GCase enzyme levels. The company plans to initiate IND-enabling studies soon, promising hope for patients with alpha synucleinopathies.

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FAQ

What is the current stock price of Gain Therapeutics (GANX)?

The current stock price of Gain Therapeutics (GANX) is $1.56 as of December 20, 2024.

What is the market cap of Gain Therapeutics (GANX)?

The market cap of Gain Therapeutics (GANX) is approximately 42.1M.

What is Gain Therapeutics, Inc.?

Gain Therapeutics, Inc. is a biotechnology company focused on discovering and developing novel small molecule therapeutics for rare genetic diseases and other serious conditions.

What diseases is Gain Therapeutics targeting?

The company targets lysosomal storage disorders, central nervous system disorders, metabolic disorders, and oncology, with a focus on GBA1 Parkinson's disease.

What is GT-02287?

GT-02287 is a clinical-stage product candidate being developed by Gain Therapeutics for the treatment of GBA1 Parkinson's disease. It aims to restore the function of the enzyme glucocerebrosidase (GCase).

How does Gain Therapeutics discover new treatments?

The company uses its proprietary Magellan™ platform, which combines AI-supported structural biology and advanced algorithms to identify novel allosteric binding sites on proteins.

What recent achievements has Gain Therapeutics made?

Recent data presented at the 20th WORLDSymposium™ showed the potential of GT-02287 to reverse motor deficits and reduce neurodegeneration biomarkers in preclinical models.

Who are Gain Therapeutics' partners?

Gain Therapeutics collaborates with organizations such as The Michael J. Fox Foundation for Parkinson’s Research and The Silverstein Foundation for Parkinson’s with GBA.

What is the Magellan™ platform?

Magellan™ is Gain Therapeutics' proprietary platform that uses AI and advanced algorithms to discover novel allosteric binding sites on disease-implicated proteins, leading to the identification of new therapeutic compounds.

What is unique about Gain Therapeutics' approach?

Gain Therapeutics' approach is unique because it focuses on allosteric modulation to restore or disrupt protein function, offering potential treatments for diseases that are currently untreatable or difficult to treat.

How does GT-02287 work?

GT-02287 works by modulating the function of the lysosomal enzyme glucocerebrosidase (GCase), which is impaired in GBA1 Parkinson's disease, helping to address the underlying cause of the disease.

Where can I find more information about Gain Therapeutics?

For more information about Gain Therapeutics, visit their website at GainTherapeutics.com or follow their updates on LinkedIn.

Gain Therapeutics, Inc.

Nasdaq:GANX

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42.15M
25.22M
5.09%
7.96%
2.58%
Biotechnology
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