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Exscientia Plc (symbol: EXAI) is revolutionizing the field of small molecule drug discovery with its cutting-edge AI and machine learning technologies. As the first company to automate drug design, Exscientia surpasses traditional human efforts by leveraging vast repositories of discovery data combined with the expertise of seasoned drug hunters. At the core of the company's operations is a sophisticated AI-driven system that can design millions of novel, project-specific compounds. These compounds are pre-assessed for key criteria such as predicted potency, selectivity, and ADME (absorption, distribution, metabolism, and excretion).
The company's knowledge-driven systems enable rapid design-make-test cycles, generating new experimental data to refine their predictions continually. This iterative process ensures unparalleled progress toward project goals and has already resulted in significant productivity gains. Exscientia can generate drug candidates in roughly one-quarter of the time required by traditional methods.
Exscientia's technology platform uniquely combines human and computational capabilities to accelerate the design of novel, safe, and efficacious compounds for clinical testing in humans. The company focuses on the discovery and development of small-molecule drug candidates, aiming to bring innovative and effective treatments to market faster.
Recent achievements include successful partnerships and collaborations with leading pharmaceutical companies and research institutions. These collaborations enhance the company's ability to integrate new data, refine its predictive models, and expand its drug discovery capabilities. Financially, Exscientia remains robust, continually investing in research and development to maintain its leading position in AI-driven drug discovery.
For investors and stakeholders, Exscientia represents a pioneering force in the pharmaceutical industry, combining advanced technology with deep scientific expertise to transform drug discovery and development.
Exscientia plc (Nasdaq: EXAI) reported significant advancements in its pipeline and financial results for 2021. Key highlights include 11 new programmes added, a $100 million upfront payment from Sanofi focused on oncology and immunology, and the achievement of preclinical milestones in collaborations with Bayer and Bristol Myers Squibb. Financially, the company generated $36.9 million in revenue, a $23.9 million increase year-over-year, with $85.3 million cash flow from collaborations. As of year-end, cash reserves stood at $758.9 million, positioning the company for future growth.
Exscientia (NASDAQ: EXAI) will announce its financial results for Q4 and the full year ended December 31, 2021, on March 23, 2022, after market close. A conference call is scheduled for March 24, 2022, at 12:30 p.m. GMT / 8:30 a.m. ET to discuss the results and showcase their AI-driven drug discovery platform. Exscientia is at the forefront of automating the drug development process, with over 25 projects in progress, aiming to transform scientific concepts into therapeutic candidates efficiently.
Rallybio Corporation (Nasdaq: RLYB) reported its 2021 financial results, highlighting a net loss of $47 million and increased R&D expenses of $26.9 million, driven by advancements in product candidates. The company is progressing with Phase 1 studies for RLYB212, targeting FNAIT, and RLYB116 for complement-related diseases, with initial data expected in 2022. Rallybio's cash position stood at $175.3 million as of December 31, 2021, supporting ongoing development efforts.
Exscientia (NASDAQ: EXAI) has partnered with the University of Oxford Target Discovery Institute to launch the Xcellomics program aimed at revolutionizing early-stage drug discovery.
By sourcing cellular functional assays from academic researchers, Xcellomics seeks to identify novel therapeutic candidates while leveraging Exscientia's AI capabilities.
The program, starting with oncology, will evaluate submissions for collaborative development, emphasizing shared data ownership between researchers and Xcellomics.
Exscientia (NASDAQ: EXAI) has announced the acceptance of three abstracts for presentation at the upcoming AACR Annual Meeting 2022 in New Orleans, showcasing the potential of its AI-driven drug discovery platform.
The abstracts focus on innovations such as targeting adenosine antagonist patient responses and profiling GTAEXS-617, a potent inhibitor of CDK7. These advances aim to improve patient outcomes in oncology by identifying responsive patient groups and enhancing drug design.
Symbotic LLC announced its fiscal Q1 2022 results, reporting revenue of $77.1 million, a significant increase from $5.5 million in Q1 2021. The adjusted EBITDA was ($21.3) million with a net income of ($23.1) million. Gross margin improved to 18.8% from (10.2)% year-over-year. The company's backlog stands at $5.3 billion. Symbotic is in a proposed business combination with SVF Investment Corp. 3, aiming for Nasdaq listing. CEO Rick Cohen highlighted rapid scaling and client deployments as key growth drivers.
Exscientia (Nasdaq: EXAI) announced participation of CEO Andrew Hopkins and CFO Ben Taylor in fireside chats at two upcoming investor conferences. The Morgan Stanley EMEA HealthTech Conference is scheduled for March 1, 2022, at 9:00 a.m. ET. The Barclays Global Healthcare Conference will take place on March 16, 2022, at 11:15 a.m. ET. Live webcasts will be available on the company’s website, with archived replays accessible for 30 days post-event. Exscientia is focused on AI-driven drug discovery with over 25 projects in its pipeline.
Exscientia has appointed Professor Charlotte Deane as Chief Scientist of Biologics AI, enhancing its leadership in AI-driven drug development. Deane, a prominent bioinformatician from the University of Oxford, will leverage her 20+ years of experience to integrate AI and protein structure design in creating new drug candidates. This strategic move is expected to accelerate Exscientia's mission to expedite medicine development. She will retain her academic roles while contributing to Exscientia’s innovative projects, which include ongoing advancements in AI-designed therapeutics.
Exscientia has announced a significant collaboration with Sanofi to develop up to 15 novel small molecule candidates targeting oncology and immunology. This agreement utilizes Exscientia's AI-driven platform to improve drug discovery, integrating patient samples for more effective candidate selection. Exscientia will receive an upfront payment of
Rallybio Corporation (NASDAQ: RLYB) announced that the first subjects have been dosed in the Phase 1 study of RLYB212, targeting fetal and neonatal alloimmune thrombocytopenia (FNAIT). A proof-of-concept study is anticipated in Q3 2022. Additionally, they are set to initiate a Phase 1 study of RLYB116, a C5 inhibitor for paroxysmal nocturnal hemoglobinuria (PNH) and generalized Myasthenia Gravis (gMG), in Q1 2022. The company is also advancing an ENPP1 inhibitor with IND-enabling studies expected in Q2 2022, enhancing their commitment to developing therapies for severe and rare diseases.
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