Elevai Labs Inc. Subsidiary, Elevai Skincare Inc., Announces Positive Results for E-Series Exosome Technology in Potential Melasma Applications

Rhea-AI Summary

Elevai Labs Inc. (NASDAQ: ELAB) has announced positive case study results for its E-Series exosome technology in potential melasma applications. The study, conducted by Dr. Chau Ngoc To Trinh in Vietnam, involved four female patients with moderate to severe mixed type melasma. A triple combination method was used, including Er:YAG and Nd:YAG lasers, followed by Elevai's topical exosome products.

Key findings include:

• Significant improvement after two months of treatment
• No melasma recurrence after six months
• Potential synergistic effects between laser therapy and exosome products

The global melasma treatment market is expected to grow from $2.85 billion in 2022 to $4.83 billion by 2030, with a CAGR of 6.8%. Elevai plans to conduct larger studies to further demonstrate the potential of combining their exosome products with laser therapy for melasma treatment.

Positive

• Positive case study results for E-Series exosome technology in melasma applications
• Significant improvement in melasma after two months of treatment
• No melasma recurrence observed after six months of follow-up
• Potential synergistic effects between laser therapy and Elevai's exosome products
• Global melasma treatment market expected to grow to $4.83 billion by 2030 with 6.8% CAGR

Negative

• Small sample size of only four patients in the case study
• geographical scope of the study (Vietnam only)
• Further studies with larger sample sizes and longer follow-up periods needed to confirm results

Medical Research Analyst

The positive case study results for Elevai's E-Series exosome technology in melasma treatment are promising, albeit preliminary. The study's small sample size (four patients) and short follow-up period (six months) limit its statistical significance. However, the reported synergistic effects of combining laser therapy with Elevai's topical exosome products are intriguing. The absence of melasma recurrence after six months is particularly noteworthy, as melasma is often challenging to treat long-term. This approach could potentially address a significant unmet need in the $2.85 billion global melasma treatment market. Future larger-scale studies will be important to validate these findings and establish the treatment's efficacy across diverse patient populations. Investors should view this as an early-stage development with potential, but await more robust clinical data before drawing definitive conclusions.

Dermatology Expert

The combination of 2940 nm Er:YAG fractional laser and 1064 nm QS Nd:YAG laser with Elevai's exosome products represents an innovative approach to melasma treatment. This multi-modal strategy targets different aspects of melasma pathogenesis: the lasers address pigmentation and textural issues, while exosomes potentially support skin repair and regeneration. The reported lack of recurrence is particularly interesting, as melasma is notorious for its high recurrence rate. However, it's important to note that the study was conducted on a specific demographic (Vietnamese women aged 35-40 with Fitzpatrick skin types III to V). The effectiveness may vary in different populations or skin types. Additionally, the mechanism by which exosomes contribute to melasma improvement needs further elucidation. While these results are encouraging, larger randomized controlled trials are necessary to establish this as a standard treatment protocol.

Market Research Analyst

Elevai's positive case study results could position the company favorably in the rapidly growing melasma treatment market. With a projected CAGR of 6.8% and an estimated market value of $4.83 billion by 2030, there's significant potential for innovative treatments. Elevai's approach combining laser therapy with exosome technology could differentiate it in a competitive landscape. However, market penetration will depend on several factors:

• Regulatory approval and clinical validation
• Cost-effectiveness compared to existing treatments
• Adoption by dermatologists and aesthetic clinics
• Patient satisfaction and long-term efficacy

The company's collaboration with Citrine Derma Clinic for future studies is a positive step towards building clinical evidence. Investors should monitor upcoming larger-scale trials and potential partnerships with key opinion leaders in dermatology, as these will be important for market acceptance and growth.

• Case Studies Highlight Potential of Elevai Exosome Technology in Melasma Care When Used with Laser Therapy.

• Early Results Show Synergistic Effects of Elevai Exosomes™ and Laser Treatments for Melasma Improvement, With No Recurrence After Six Months.

NEWPORT BEACH, Calif., Sept. 10, 2024 (GLOBE NEWSWIRE) -- Elevai Labs, Inc. (NASDAQ: ELAB) (“Elevai” or the “Company”), a pioneering force in medical aesthetics, today announced positive case study results from patients undergoing laser therapy followed by use of Elevai E-Series for applications in melasma. Elevai believes that these case studies can be the premise for future exosome research on effective melasma solutions.

Melasma is a common skin condition characterized by the appearance of hyperpigmented patches and spots, typically on the face. The condition primarily affects adult women, especially those with Fitzpatrick skin types III to V.¹ Management of melasma typically involves daily sun protection followed by a variety of treatments, including topical applications, oral therapies, chemical peels, microneedling, laser procedures, and phototherapy.²

The case study assessments came from four female Vietnamese patients, aged 35 to 40 years old, diagnosed with moderate to severe mixed type melasma. Melasma lesions were concentrated and localized on both cheeks in all four patients. The Elevai E-Series was used in a study by renowned dermatologist Dr. Chau Ngoc To Trinh of the Citrine Derma Clinic in Ho Chi Minh City, Vietnam.

A triple combination method was applied, including 2940 nmEr:YAG fractional laser, 1064nm QS Nd:YAG laser and Elevai’s topical exosome products, Elevai empower™ and Elevai enfinity™, the E-Series. The four case studies on individuals with melasma experienced significant improvement after two months of using Elevai topical exosome products following laser treatment. After six months of follow-up, there was no melasma recurrence.

“Early results suggest that the combination of aesthetic laser treatment, followed by topical exosome use can be synergistic as a melasma solution,” said Jordan R. Plews, PhD, Chief Executive Officer of Elevai Skincare Inc. “The laser therapy breaks down melanin in the epidermis, while exosomes absorb into the skin and support the skin’s natural repair mechanisms, resulting in skin that appears naturally healthier, more balanced, and radiant.”

Data Bridge Market Research predicts that the global melasma treatment market, which reached $2.85 billion in 2022, will grow to $4.83 billion by 2030 and is expected to register a compound annual growth rate (CAGR) of 6.8% during the forecast period. Elevai and Citrine Derma Clinic are planning to perform future studies with larger sample sizes and longer follow-up periods to demonstrate the potential role of combining Elevai’s topical exosome products with laser therapy for melasma.

The complete results of this study are available for viewing at: https://elevaiskincare.com/pages/results

About Elevai Labs Inc.

Elevai Labs Inc. (NASDAQ: ELAB) specializes in medical aesthetics and biopharmaceutical drug development, focusing on innovations for skin aesthetics and treatments tied to obesity and metabolic health. The Company operates a diverse portfolio of three wholly owned subsidiaries across the medical aesthetics and biopharmaceutical sectors, Elevai Skincare Inc., Elevai Biosciences Inc., and Elevai Research Inc. For more information please visit www.elevailabs.com.

About Elevai Skincare Inc.

Elevai Skincare Inc., a subsidiary of Elevai Labs Inc., is a medical aesthetics company developing and commercializing cutting-edge physician-dispensed skin and hair care applications. Elevai Skincare Inc. develops cosmetic products for the physician-dispensed market, with a focus on leveraging novel proprietary science-backed technologies, including its stem cell exosome technology. For more information, please visit www.elevaiskincare.com.

Forward-Looking Statements

Statements contained in this press release regarding matters that are not historical facts are “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995, as amended. Words such as “believes,” “expects,” “plans,” “potential,” “would” and “future” or similar expressions such as “look forward” are intended to identify forward-looking statements. Although the Company believes that the expectations expressed in these forward-looking statements are reasonable, it cannot assure you that such expectations will turn out to be correct, and the Company cautions investors that actual results may differ materially from the anticipated results. These forward-looking statements are based only on our current beliefs, expectations and assumptions regarding the future of our business, future plans and strategies, projections, anticipated events and trends, the economy, activities of regulators and future regulations and other future conditions. Because forward-looking statements relate to the future, they are subject to inherent uncertainties, risks and changes in circumstances that are difficult to predict and many of which are outside of our control. Therefore, you should not rely on any of these forward-looking statements. These risks and uncertainties include, among others: Elevai’s limited operating history and historical losses; Elevai’s ability to raise additional funding to complete the development and any commercialization of its product candidates; Elevai’s dependence on the success of its product candidates EL-22 and EL-32; that Elevai may be delayed in initiating, enrolling or completing any clinical trials; competition from third parties that are developing products for similar uses; Elevai’s ability to obtain, maintain and protect its intellectual property; Elevai’s dependence on third parties in connection with manufacturing, clinical trials and preclinical studies; and Elevai’s expectations regarding its growth, strategy, progress and the design, objectives and timing of its studies.

These and other risks are described more fully in Elevai’s filings with the Securities and Exchange Commission (“SEC”), including the “Risk Factors” section of the Company’s Annual Report on Form 10-K for the year ended December 31, 2023, filed with the SEC on March 29, 2024, and its other documents subsequently filed with or furnished to the SEC. All forward-looking statements contained in this press release speak only as of the date on which they were made. Except to the extent required by law, the Company undertakes no obligation to update such statements to reflect events that occur or circumstances that exist after the date on which they were made.

Media Contact:
Makenzie Mann
contact@elevailabs.com

¹ Sheth, V.M.; Pandya, A.G. Melasma: A Comprehensive Update: Part i. J. Am. Acad. Dermatol 2011, 65, 689–697.

²Jiryis B, Toledano O, Avitan-Hersh E, Khamaysi Z. Management of Melasma: Laser and Other Therapies-Review Study. J Clin Med. 2024 Mar 3;13(5):1468.

³Global Melasma Treatment Market – Industry Trends and Forecast to 2030

FAQ

What were the results of Elevai Labs' (ELAB) case study on melasma treatment?

Elevai Labs' case study showed significant improvement in melasma after two months of treatment using their E-Series exosome technology in combination with laser therapy. No melasma recurrence was observed after six months of follow-up.

How does Elevai Labs' (ELAB) E-Series exosome technology work for melasma treatment?

Elevai's E-Series exosome technology is used in combination with laser therapy. The laser breaks down melanin in the epidermis, while the exosomes absorb into the skin and support natural repair mechanisms, resulting in healthier and more balanced-looking skin.

What is the market potential for melasma treatments according to Elevai Labs' (ELAB) press release?

According to the press release, the global melasma treatment market is expected to grow from $2.85 billion in 2022 to $4.83 billion by 2030, with a compound annual growth rate (CAGR) of 6.8%.

What are Elevai Labs' (ELAB) plans for future melasma treatment studies?

Elevai Labs plans to conduct future studies with larger sample sizes and longer follow-up periods to further demonstrate the potential of combining their topical exosome products with laser therapy for melasma treatment.