Newly Published Study Demonstrates Significant Clinical Utility of Daxor’s Blood Volume (BVA-100®) Diagnostic in the Evaluation of Heart Failure

Rhea-AI Summary

Daxor Corporation (Nasdaq: DXR) announced a study published in the Journal of Cardiac Failure that highlights the effectiveness of its BVA-100 blood test for assessing heart failure. The study demonstrated that traditional surrogate markers fail to measure intravascular volume overload accurately, an essential factor in managing heart failure. The BVA-100 has shown a critical role in reducing hospital readmissions and improving patient outcomes for over 6 million Americans suffering from heart failure. CEO Michael Feldschuh emphasized the test's clinical importance in guiding treatment decisions.

Positive

• The BVA-100 blood test accurately measures intravascular volume overload in heart failure patients.
• The study supports the BVA-100's clinical utility, showing potential to reduce hospital readmissions.
• Daxor has conducted over 60,000 tests, enhancing hospital performance metrics.

Negative

• Traditional surrogate markers for measuring volume overload were shown to be ineffective.

Study Highlighted That Only The BVA-100 Accurately Measures Volume Derangements Compared to Commonly Used Surrogates

Oak Ridge, TN, Nov. 03, 2022 (GLOBE NEWSWIRE) -- Daxor Corporation (Nasdaq: DXR), the global leader in blood volume measurement technology, today announces a new study in the prestigious Journal of Cardiac Failure demonstrating the importance and clinical utility of Daxor’s BVA-100 blood test in heart failure (HF). The researchers showed that Daxor’s BVA-100 was able to measure intravascular volume overload in heart failure patients – a key metric targeted to successfully manage heart failure. Common surrogate markers and clinical evaluation to assess volume overload in contrast were shown to be ineffective at making a comparative clinically actionable measure, despite common usage in many hospitals.

The Journal of Cardiac Failure is the official peer reviewed journal of the Heart Failure Society of America and the Japanese Heart Failure Society. Data from this study was cited at the 2022 Annual Heart Failure Society of America meeting in a session focused on congestion measurement which called for the use of the BVA-100 diagnostic. Dr. Wayne Miller, Mayo Clinic, cited data from this study and concluded that “there are limitations to the use of the surrogates, if you need to know information about volume [in heart failure patients], you need to measure volume.”

The study titled, “Blood Volume Analysis and Hemodynamic Measures of Vascular Compliance in Patients with Worsening Heart Failure,” assessed the relationship between blood volume, resting, and stress cardiovascular pressures in worsening HF. Patients presenting to the hospital or outpatient clinic with clinical worsening HF underwent blood volume analysis measured with Daxor’s BVA-100 diagnostic blood test, right heart catheterization, provocative testing including blood pressure measurement, leg raises, breathing techniques, and patient symptoms and physical exam findings.

The study results showed little to no correlation between patient symptoms, physical exam or cardiac pressures as compared to direct blood volume measures. Vishal N. Rao, M.D., MPH, lead investigator of the study, concluded, “These findings add to the growing evidence concerning hemodynamic relationships with blood volume, and such findings uniquely highlight discordance in blood volume with dynamic resting supine and stress- induced cardiac pressures during worsening HF episodes.”

“More than 6 million Americans suffer from heart failure, one of the most prevalent, complex, and deadly diseases leading to nearly one million deaths and one million hospitalizations annually,” said Michael Feldschuh, CEO and President of Daxor Corporation. “Worsening HF is associated with exceedingly high 30-day mortality and risk for rehospitalization. Our test informs clinicians with critical information to help manage and treat volume derangements in complex HF patients and past studies in peer-reviewed journals have shown substantial improvements in reducing mortality, hospital readmission, length of stay, and costs from the use of our diagnostic.”

About Daxor Corporation

Daxor Corporation (Nasdaq: DXR), is the global leader in blood volume measurement technology focused on blood volume testing innovation. We developed and market the BVA-100^® (Blood Volume Analyzer), the first diagnostic blood test cleared by the FDA to provide safe, accurate, objective quantification of blood volume status and composition compared to patient-specific norms. Over 60,000+ tests have been performed at leading hospital centers across the U.S., enhancing hospital performance metrics in a broad range of surgical and medical conditions, including significantly reducing mortality and readmissions in heart failure and critical care. Daxor has several ongoing multicenter trials in the areas of COVID-19 and heart failure treatment with support from the NIH and is under contract developing analyzers to improve combat casualty care with the U.S. Department of Defense. Daxor's mission is to advance healthcare by enabling optimal fluid management with blood volume analysis. Daxor’s vision is optimal blood volume for all. For more information, please visit our website at Daxor.com.

Forward-Looking Statements

Certain statements in this release may include forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995, including without limitation, statements regarding the impact of hiring sales staff and expansion of our distribution channels. Forward-looking statements are predictions, projections and other statements about future events that are based on current expectations and assumptions and, as a result, are subject to risks and uncertainties. Many factors could cause actual future events to differ materially from the forward-looking statements in this release, including, without limitation, those risk associated with our post-market clinical data collection activities, benefits of our products to patients, our expectations with respect to product development and commercialization efforts, our ability to increase market and physician acceptance of our products, potentially competitive product offerings, intellectual property protection, FDA regulatory actions, our ability to integrate acquired businesses, our expectations regarding anticipated synergies with and benefits from acquired businesses, and additional other risks and uncertainties described in our filings with the SEC. Forward-looking statements speak only as of the date when made. Daxor does not assume any obligation to publicly update or revise any forward-looking statements, whether as a result of new information, future events or otherwise.

Investor Relations Contact:
Bret Shapiro
Sr. Managing Partner, CORE IR
516-222-2560
brets@coreir.com

FAQ

What does the new study about Daxor Corporation's BVA-100 test reveal?

The study shows that the BVA-100 accurately measures intravascular volume overload in heart failure patients, unlike commonly used surrogate markers.

How does the BVA-100 blood test impact heart failure treatment?

The BVA-100 helps clinicians manage heart failure more effectively, potentially reducing hospital readmissions and mortality rates.

What is the significance of Daxor Corporation's study in the Journal of Cardiac Failure?

The study provides evidence of the BVA-100's importance in clinical practice for assessing heart failure, leading to better patient management.

When was the study on Daxor's BVA-100 published?

The study was published on November 3, 2022.

What are the implications of the findings from Daxor's heart failure study?

The findings may lead to improved management strategies for heart failure patients by utilizing accurate blood volume measurements.