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Corvus Pharmaceuticals, Inc. - CRVS STOCK NEWS

Welcome to our dedicated page for Corvus Pharmaceuticals news (Ticker: CRVS), a resource for investors and traders seeking the latest updates and insights on Corvus Pharmaceuticals stock.

Corvus Pharmaceuticals, Inc. (NASDAQ: CRVS) is a pioneering clinical-stage biopharmaceutical company focused on the development of novel immunotherapies to treat a broad spectrum of cancers and immune diseases. The company's core innovation is the selective inhibition of interleukin-2-inducible T cell kinase (ITK), which plays a crucial role in T cell and natural killer (NK) cell immune functions. Corvus' lead investigational product, soquelitinib (formerly CPI-818), has shown promise in optimizing T cell differentiation and enhancing immune responses against tumors, as well as in the management of autoimmune diseases.

Corvus is advancing soquelitinib through a Phase 3 registrational trial for relapsed peripheral T cell lymphoma (PTCL), an aggressive and typically treatment-resistant form of non-Hodgkin’s lymphoma. The company’s focus on ITK inhibition offers a new therapeutic approach, given the lack of FDA-approved treatments for relapsed PTCL. Soquelitinib has demonstrated the ability to prevent T cell exhaustion and promote the generation of cytotoxic killer T cells, critical in cancer therapy.

In addition, Corvus is investigating soquelitinib for other immune-mediated conditions, including atopic dermatitis. The company recently initiated a randomized, double-blind Phase 1 clinical trial to evaluate soquelitinib in patients with moderate to severe atopic dermatitis, aiming to provide an oral treatment alternative to current injectable biologics.

Other promising candidates in Corvus' pipeline include ciforadenant, an adenosine A2A receptor inhibitor that disables tumors' immune evasion mechanisms, and mupadolimab, a monoclonal antibody targeting CD73. These candidates are being studied for their efficacy in combination therapies for various cancers, including head and neck cancers and non-small cell lung cancer.

Financially, Corvus maintains a strong position, having raised significant capital through direct offerings to support its clinical trials and operational needs. With cash reserves projected to fund operations into late 2025, Corvus is well-positioned to achieve substantial milestones in its clinical programs. The company continues to foster critical partnerships, including collaborations with Angel Pharmaceuticals for the Chinese market.

Latest news highlights Corvus' progress in clinical trials and strategic financing moves, underscoring its commitment to bringing innovative immunotherapies to patients in need. For more information, visit the Corvus Pharmaceuticals website.

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Corvus Pharmaceuticals (Nasdaq: CRVS) has announced its participation in the H.C. Wainwright 24th Annual Global Investment Conference from September 12-14, 2022. CEO Richard A. Miller will present a pre-recorded corporate overview, available on-demand starting September 12 at 7:00 am ET. The presentation will be accessible for 90 days on the Corvus investor relations webpage. Corvus focuses on developing innovative treatments for T-cell lymphomas, notably its lead candidate CPI-818 and other programs such as ciforadenant and mupadolimab.

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Corvus Pharmaceuticals (CRVS) provided a business update and financial results for Q2 2022. The company is prioritizing CPI-818 for T cell lymphomas and related autoimmune diseases, showing promising early clinical data. Additionally, it plans a Phase 2 trial for ciforadenant in metastatic renal cell cancer with the Kidney Cancer Clinical Trials Consortium in Q3 2022. However, development of mupadolimab for lung cancer is paused to focus resources. As of June 30, 2022, cash reserves amounted to $56.7 million, projected to fund operations into early 2024.

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Corvus Pharmaceuticals (Nasdaq: CRVS) announced a conference call and webcast scheduled for August 8, 2022, at 4:30 PM ET to report second quarter 2022 financial results and provide a business update. The call can be accessed via phone or through a live webcast on Corvus' investor relations page, with a replay available for 90 days. Corvus focuses on developing novel therapies, including mupadolimab (CPI-006) and CPI-818, for the treatment of various cancers.

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Corvus Pharmaceuticals (Nasdaq: CRVS) has appointed Dr. James Rosenbaum as Senior Vice President of Research to lead the development of CPI-818, an ITK inhibitor aimed at treating immune disorders and T cell lymphomas. CPI-818 is currently in a Phase 1/1b clinical trial with promising interim results that may support future Phase 2 trials. Dr. Rosenbaum brings extensive experience in immunology and autoimmune diseases, enhancing the company's research capabilities in clinical and preclinical settings.

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Corvus Pharmaceuticals (Nasdaq: CRVS) hosted an R&D Symposium showcasing interim data from the Phase 1/1b study of CPI-818 in patients with relapsed T cell lymphomas. The trial identified a 200 mg optimal dose, with notable patient responses, including a complete remission lasting 19 months. Key findings indicate CPI-818's potential in enhancing anti-tumor immunity without directly killing cancer cells. The company plans to expand its study, with future data releases anticipated, and aims to initiate a global Phase 2 trial if trends continue.

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Corvus Pharmaceuticals (CRVS) reported its Q1 2022 financial results, revealing cash reserves of $62.9 million, down from $69.5 million at the end of 2021. The net loss narrowed to $8.3 million compared to $11.6 million in Q1 2021. The company is advancing three clinical candidates, including mupadolimab for non-small cell lung cancer and ciforadenant for renal cell cancer, with trials set to start later in the year. Corvus will host an R&D Symposium on May 10, 2022, to discuss these clinical efforts.

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Corvus Pharmaceuticals will host an R&D Symposium on May 10, 2022, in New York City, from 9:00 AM to 11:30 AM ET. The event aims to update on three clinical programs: anti-CD73 (mupadolimab), adenosine 2A receptor antagonist (ciforadenant), and ITK inhibitor (CPI-818) in T cell lymphomas. The symposium will feature insights from Corvus President Richard A. Miller, M.D., along with expert speakers from Stanford University and Angel Pharmaceuticals. The event will be webcast live and available for replay for 90 days.

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Corvus Pharmaceuticals (Nasdaq: CRVS) provided a business update and 2021 financial results, highlighting progress in clinical programs targeting cancer. The firm plans a Phase 2 trial for mupadolimab in advanced non-small cell lung cancer and has expanded CPI-818 trials in China for T cell lymphomas. Cash reserves increased to $69.5 million from $44.3 million year-over-year, with a projected net cash usage of $34-$36 million in 2022. However, the net loss for 2021 was $43.2 million, a decline from a prior gain in 2020, primarily due to the absence of significant one-time gains.

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Corvus Pharmaceuticals (Nasdaq: CRVS) will hold a conference call on March 10, 2022, at 4:30 pm ET to discuss business updates and report its Q4 and full year 2021 financial results. Investors can join the call by dialing 1-877-407-0784 for domestic or 1-201-689-8560 for international access. Registration requires the conference ID 13727689. The call will also be available via webcast, with a replay accessible on the company’s website for 90 days.

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Corvus Pharmaceuticals (NASDAQ: CRVS) announced that Angel Pharmaceuticals has commenced a Phase 1/1b clinical trial for CPI-818, a small molecule ITK inhibitor, targeting relapsed/refractory T-cell lymphomas in China. This marks the first clinical application of CPI-818 in the region, addressing a significant unmet clinical need, as T-cell lymphomas are more prevalent in China. The trial will assess various dosing regimens and evaluate safety, tolerability, and preliminary efficacy amongst patients who have failed standard therapies.

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FAQ

What is the current stock price of Corvus Pharmaceuticals (CRVS)?

The current stock price of Corvus Pharmaceuticals (CRVS) is $8.19 as of November 15, 2024.

What is the market cap of Corvus Pharmaceuticals (CRVS)?

The market cap of Corvus Pharmaceuticals (CRVS) is approximately 504.2M.

What is Corvus Pharmaceuticals' lead product candidate?

Corvus Pharmaceuticals' lead product candidate is soquelitinib (formerly CPI-818), an investigational small molecule drug designed to selectively inhibit ITK (interleukin-2-inducible T cell kinase).

What conditions is Corvus Pharmaceuticals targeting with soquelitinib?

Soquelitinib is being developed for the treatment of relapsed peripheral T cell lymphoma (PTCL), atopic dermatitis, and potentially other autoimmune and cancer indications.

What is the significance of ITK inhibition in Corvus Pharmaceuticals' research?

ITK inhibition plays a key role in optimizing T cell differentiation and enhancing immune responses, which can be critical for treating cancers and immune diseases.

What other products are in Corvus Pharmaceuticals' pipeline?

Corvus' pipeline includes ciforadenant (an adenosine A2A receptor inhibitor) and mupadolimab (a monoclonal antibody targeting CD73), both of which are being evaluated in combination therapies for various cancers.

What recent financial developments have supported Corvus Pharmaceuticals' research?

Corvus recently raised approximately $30.6 million through a registered direct offering, bolstering its cash reserves to fund ongoing and upcoming clinical trials.

What is the background of Corvus Pharmaceuticals?

Corvus Pharmaceuticals is a clinical-stage biopharmaceutical company specializing in novel immunotherapies. It was co-founded by Richard A. Miller, M.D., who also serves as its president and CEO.

What partnerships does Corvus Pharmaceuticals have?

Corvus Pharmaceuticals collaborates with Angel Pharmaceuticals to develop and commercialize its leading candidates in China and has invested heavily in top-tier scientific talent and innovative research.

How is Corvus Pharmaceuticals addressing the unmet needs in relapsed PTCL?

Corvus is advancing soquelitinib through a Phase 3 registrational trial for relapsed PTCL, aiming to provide a new therapy for a condition with limited existing treatment options.

How is soquelitinib being evaluated for atopic dermatitis?

A Phase 1 clinical trial for soquelitinib in patients with moderate to severe atopic dermatitis has been initiated to evaluate its safety, tolerability, and efficacy.

What makes mupadolimab unique in Corvus Pharmaceuticals' research?

Mupadolimab is designed to target CD73, stimulating B cells and blocking immunosuppressive adenosine production, enhancing the immune response in cancer treatments.

Corvus Pharmaceuticals, Inc.

Nasdaq:CRVS

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CRVS Stock Data

504.17M
64.26M
4.02%
43.95%
3.91%
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