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Caribou Biosciences, Inc. - CRBU STOCK NEWS

Welcome to our dedicated page for Caribou Biosciences news (Ticker: CRBU), a resource for investors and traders seeking the latest updates and insights on Caribou Biosciences stock.

Caribou Biosciences, Inc. (CRBU) is a clinical-stage biotechnology company pioneering advancements in genome engineering. Leveraging revolutionary CRISPR-Cas9 technology, Caribou specializes in developing innovative cellular engineering solutions. Their technology, which pairs Cas9 with guide RNA to facilitate precise DNA modifications, is being harnessed for sophisticated gene knock-outs and knock-ins. Caribou's tools provide transformative capabilities across various sectors, including biological research, therapeutic development, agricultural biotechnology, and industrial biotechnology.

At the forefront of biopharmaceutical innovation, Caribou is dedicated to applying its proprietary CRISPR hybrid RNA-DNA (chRDNA) platform to create next-generation genome-edited cell therapies. Their pipeline includes allogeneic CAR-T and CAR-NK cell therapies, aimed at treating patients with hematologic malignancies and solid tumors.

Recent milestones include the FDA's feedback on a Phase 3 trial for CB-010, an allogeneic anti-CD19 CAR-T cell therapy targeting large B cell lymphoma (LBCL). The ongoing ANTLER Phase 1 trial has shown promising results, with CB-010 receiving Regenerative Medicine Advanced Therapy (RMAT), Fast Track, and Orphan Drug designations. Caribou is also expanding CB-010's potential application to lupus nephritis and extrarenal lupus, with a GALLOP Phase 1 trial planned for late 2024.

Financially, Caribou reported a net loss of $41.2 million for Q1 2024, with $345.9 million in cash, cash equivalents, and marketable securities, expected to fund operations into Q1 2026. Their strategic partnerships, including a collaboration with Pfizer, have bolstered their financial standing.

Caribou continues to push the boundaries of genome editing with its chRDNA technology, significantly improving the precision of genome edits. Their commitment to transforming patient lives through cutting-edge science positions them as a leader in the biotech landscape.

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Precision BioSciences, Inc. (Nasdaq: DTIL) reported their first quarter 2024 financial results and provided a business update. The company is focused on advancing its wholly owned gene editing programs for Hepatitis B virus and primary mitochondrial myopathy. Precision also exercised the option to return three preclinical programs for internal development or with partners. They monetized CAR T assets through licensing deals and completed a $40 million common stock offering to extend cash runway into H2 2026. Financially, Precision had $137.8 million in cash and cash equivalents as of March 31, 2024, with total revenues of $17.6 million for the quarter. Research and development expenses increased to $13.3 million, while general and administrative expenses decreased to $8.4 million. Net income from continuing operations was $8.6 million for the quarter.

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Caribou Biosciences, Inc. (Nasdaq: CRBU) reported its first quarter 2024 financial results and pipeline progress, highlighting advancements in clinical-stage programs for hematologic malignancies and autoimmune diseases. With $345.9 million in cash, cash equivalents, and marketable securities, the company expects to fund operations into Q1 2026. Notable milestones include presenting clinical data at the 2024 ASCO Annual Meeting, initiating the GALLOP Phase 1 trial, and providing updates on ongoing trials. Despite a slight decrease in licensing and collaboration revenue, increased R&D and G&A expenses led to a net loss of $41.2 million for Q1 2024.

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Caribou Biosciences, Inc. (Nasdaq: CRBU) will participate in upcoming investor conferences, including the 2024 RBC Capital Markets Global Healthcare Conference and BofA Securities 2024 Health Care Conference. The company will present at these events, offering webcasts for more information.

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Caribou Biosciences, Inc. (Nasdaq: CRBU) will present initial dose expansion data from the CB-010 ANTLER Phase 1 Trial in relapsed/refractory B-NHL at the 2024 ASCO Annual Meeting. The company also announced another abstract presentation for the CB-012 AMpLify trial. The abstracts will be available on May 23, 2024, with poster presentations on June 3, 2024.
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Caribou Biosciences announces an oral presentation on in vivo Cas12a chRDNA genome editing at the 27th Annual Meeting of the American Society of Gene and Cell Therapy (ASGCT). The presentation will focus on the efficient use of Cas12a chRDNA genome-editing technology for in vivo hepatic gene disruption, with details on the title, presenter, date, time, session, and abstract number. The abstract will be available on the ASGCT Annual Meeting website on April 22, 2024, and the presentation on Caribou's website on May 10, 2024.
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Caribou Biosciences, Inc. (CRBU) receives FDA clearance for IND application of CB-010, a CAR-T cell therapy for lupus nephritis and extrarenal lupus. GALLOP Phase 1 trial to start by YE 2024. Positive initial safety and efficacy in ANTLER trial for B-NHL. CB-010's potential to revolutionize lupus treatment by targeting CD19-positive B cells. CB-010 aims for sustained drug-free remission through deep depletion of disease-causing B cells. Unique chRDNA technology for precise CAR insertion in T cell genome. GALLOP trial to include partial HLA matching for improved outcomes.
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Precision BioSciences, Inc. (DTIL) announced financial results for 2023, highlighting key achievements such as initiating final IND/CTA enabling studies for PBGENE-HBV, completing licensing agreements with Imugene, TG Therapeutics, and Caribou Biosciences, and completing a $40 million public offering to extend cash runway. The company aims to submit IND and/or CTA for PBGENE-HBV in 2024 and PBGENE-PMM in 2025, advancing gene editing programs and differentiating ARCUS within the field.
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Caribou Biosciences, Inc. (CRBU) reports significant progress in clinical trials, dosing the 30th patient in the CB-010 ANTLER Phase 1 trial and initiating the CB-012 AMpLify Phase 1 trial. The company has $372.4 million in cash and securities to fund operations until Q1 2026. Financially, Caribou saw an increase in licensing revenue but also higher R&D and G&A expenses, resulting in a net loss for Q4 2023 and full year 2023.
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Caribou Biosciences, Inc. (CRBU) announced the presentation of preclinical data on CB-012, an anti-CLL-1 CAR-T cell therapy for r/r AML at AACR Annual Meeting 2024. The therapy shows specific cytotoxicity in AML xenograft models.
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Caribou Biosciences, Inc. (CRBU) announces its participation in key investor conferences to discuss its CRISPR genome-editing technology. The company will be present at Citi's 2024 Virtual Oncology Leadership Summit, Leerink Global Biopharma Conference, Barclays Global Healthcare Conference, and H.C. Wainwright 2nd Annual Cell Therapy Virtual Conference. Webcasts will be accessible on Caribou's website for 30 days post-event.
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FAQ

What is the current stock price of Caribou Biosciences (CRBU)?

The current stock price of Caribou Biosciences (CRBU) is $1.8 as of December 20, 2024.

What is the market cap of Caribou Biosciences (CRBU)?

The market cap of Caribou Biosciences (CRBU) is approximately 163.4M.

What does Caribou Biosciences specialize in?

Caribou Biosciences specializes in genome engineering using CRISPR-Cas9 technology to develop innovative cellular engineering solutions.

What is CB-010?

CB-010 is Caribou's lead allogeneic anti-CD19 CAR-T cell therapy, currently in clinical trials for large B cell lymphoma and lupus.

What recent FDA feedback did Caribou receive?

The FDA provided feedback on a Phase 3 trial for CB-010, stating that the proposed comparator arm is acceptable.

How is Caribou's financial health?

Caribou reported a net loss of $41.2 million for Q1 2024, with $345.9 million in cash and equivalents, sufficient to fund operations into Q1 2026.

What is chRDNA technology?

chRDNA (CRISPR hybrid RNA-DNA) technology is Caribou's proprietary platform that allows for more precise genome editing compared to traditional methods.

What are the applications of Caribou's technology?

Applications include basic and applied biological research, therapeutic development, agricultural biotechnology, and industrial biotechnology.

What designations has CB-010 received from the FDA?

CB-010 has been granted Regenerative Medicine Advanced Therapy (RMAT), Fast Track, and Orphan Drug designations.

What is the ANTLER trial?

The ANTLER trial is a Phase 1 clinical trial evaluating CB-010 in patients with large B cell lymphoma.

What is Caribou's collaboration with Pfizer?

Caribou's collaboration with Pfizer includes a $25 million equity investment, supporting their financial and developmental goals.

What upcoming trials are planned for CB-010?

Caribou plans to initiate the GALLOP Phase 1 trial for CB-010 in lupus nephritis and extrarenal lupus by the end of 2024.

Caribou Biosciences, Inc.

Nasdaq:CRBU

CRBU Rankings

CRBU Stock Data

163.45M
80.73M
10.04%
62.54%
8.19%
Biotechnology
Biological Products, (no Disgnostic Substances)
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United States of America
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