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Compass Therapeutics, Inc. - CMPX STOCK NEWS

Welcome to our dedicated page for Compass Therapeutics news (Ticker: CMPX), a resource for investors and traders seeking the latest updates and insights on Compass Therapeutics stock.

Compass Therapeutics, Inc. (Nasdaq: CMPX) is a clinical-stage biopharmaceutical company headquartered in Boston, Massachusetts. Founded in 2014, Compass focuses on developing proprietary antibody-based therapeutics to treat a variety of human diseases, with a strong emphasis on oncology.

The company’s core mission is to thoroughly address the tumor-immune synapse by utilizing combinations of human monoclonal antibodies, multiclonals, and engineered protein constructs. Compass industrializes antibody discovery and decentralizes biologic validation through a partnership-first mentality, leveraging best-in-class technologies and top-tier academic laboratories globally. All novel scientific insights are validated extensively within Compass's own labs before proceeding to proprietary combination therapeutics aimed at human clinical trials.

In 2015, Compass secured a $120 million Series A financing to support its ambitious plans to build a fully-integrated biopharmaceutical company. The company’s robust pipeline includes three primary product candidates—CTX-009, CTX-471, and CTX-8371. CTX-009 is a bispecific antibody combining DLL4 and VEGF-A inhibitors, CTX-471 is a CD137 agonist, and CTX-8371 is a PD-1 x PD-L1 bispecific antibody. These candidates are in various stages of clinical development, targeting key pathways in angiogenesis, immune response activation, and immunosuppressive mechanisms within the tumor microenvironment.

Recently, Compass has achieved significant milestones. The company reported top-line data showing promising results in its Phase 2 COMPANION-003 trial and Phase 2/3 COMPANION-002 trial. Additionally, the FDA granted Fast Track Designation to CTX-009 in combination with paclitaxel for metastatic or locally advanced biliary tract cancer. Compass continues to make strides in advancing its product candidates through both standalone therapies and combinations with its proprietary pipeline antibodies.

Financially, Compass maintains a strong position, with a year-end 2023 cash balance of $152 million, extending its cash runway into mid-2026. The company’s net loss for 2023 was $42.5 million, showing a slight increase from the previous year, reflecting its intensified clinical and manufacturing activities.

Looking forward, Compass plans to continue its clinical trials and explore additional therapeutic areas. Key leadership changes and additions, such as the appointment of Vered Bisker-Leib, PhD, as CEO, reflect the company’s commitment to steering towards innovation and growth.

For more detailed and updated information, visit the Compass Therapeutics website at https://www.compasstherapeutics.com.

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Compass Therapeutics, Inc. (Nasdaq: CMPX) announced that CEO Thomas J. Schuetz, MD, PhD, will present at the Piper Sandler 33rd Annual Healthcare Conference held virtually from November 29 to December 2, 2021. The presentation will be available on-demand from November 22 to December 2, 2021. Compass Therapeutics focuses on developing proprietary antibody-based therapeutics targeting cancer through modulating immune responses and angiogenesis. Founded in 2014 and based in Boston, Massachusetts, the company aims to advance its clinical pipeline.

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Compass Therapeutics reported progress in its clinical studies and financial results for Q3 2021. The company advanced CTX-009 to the second stage of a Phase 2a study, with a 29% overall response rate observed in 17 patients. CTX-471 demonstrated two partial responses in melanoma patients. The recent public offering raised $125 million, extending its cash runway into Q4 2024. R&D expenses decreased to $3.2 million, and general and administrative expenses dropped to $2.7 million. The net loss was $6 million, or $0.10 per share, an improvement from the previous year.

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Compass Therapeutics, Inc. announced a public offering of 35,715,000 shares at $3.50 each, expected to raise approximately $125 million. The offering will close on November 4, 2021, and includes an option for underwriters to purchase an additional 5,357,250 shares. This follows the company's listing on the Nasdaq Capital Market under the symbol CMPX, effective November 2, 2021. Proceeds will fund ongoing clinical trials and operations. SVB Leerink is the book-running manager for the offering.

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Compass Therapeutics, Inc. announces an underwritten public offering of shares of common stock, intending to secure its listing on the Nasdaq Capital Market under the symbol CMPX. The company expects to grant underwriters a 30-day option to purchase an additional 15% of the shares. Proceeds from the offering will fund clinical trials for ongoing operations and general corporate purposes. Offering details are based on a previously effective shelf registration statement. SVB Leerink is the book-running manager.

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Compass Therapeutics (CMPX) announced progress on the Phase 2a study of CTX-009 for biliary tract cancers, initiated in Q1 2021 by Handok Pharmaceuticals. The study has met its criteria to advance, revealing a preliminary overall response rate of 29% with five partial responses from 17 patients. Additionally, 100% experienced stable disease or better. Compass plans to submit an Investigational New Drug (IND) application to the FDA this quarter, with a Phase 2 study anticipated in Q2 2022, aiming to enhance treatment options for cholangiocarcinoma.

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Compass Therapeutics (OTC:CMPX) presented promising clinical data for CTX-009, a bispecific antibody targeting DLL4 and VEGF-A, at the AACR-NCI-EORTC conference. In a Phase 1 trial involving heavily pre-treated patients with colorectal and gastric cancers, CTX-009 showed an overall response rate (ORR) of 19% at recommended doses, with a disease control rate (DCR) of 69%. The drug was well tolerated, with no dose-limiting toxicities reported. Ongoing studies include a Phase 1b combination trial and a Phase 2 trial, enhancing its potential as a treatment for resistant solid tumors.

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Compass Therapeutics, Inc. (OTC:CMPX) announced that data from its Phase 1 study of CTX-009, a bispecific antibody targeting DLL4 and VEGF-A, has been selected for oral presentation at the AACR-NCI-EORTC conference from October 7-10, 2021. The presentation will highlight safety, tolerability, and clinical activity data in patients with anti-VEGF-resistant solid tumors. CTX-009 has shown partial responses in heavily pre-treated patients and is currently advancing to Phase 1b and Phase 2 combination studies.

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Compass Therapeutics, Inc. (OTC:CMPX), a clinical-stage biotechnology firm, announced that CEO Thomas Schuetz will participate in a fireside chat at the Citi 16th Annual Biopharma Conference on September 8, 2021, at 3:15 PM ET. The event will be accessible via the company’s website post-presentation. Compass Therapeutics focuses on developing proprietary antibody-based therapeutics targeting oncology, particularly through understanding angiogenesis and the immune system. Founded in 2014 and headquartered in Boston, the company aims to enhance anti-tumor responses through innovative therapies.

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Compass Therapeutics (OTCQB: CMPX) has announced a definitive merger agreement with TRIGR Therapeutics, a private oncology firm. Compass will acquire TRIGR through a stock-for-stock transaction, approved unanimously by both companies' boards. At the center of the deal is CTX-009, a bispecific antibody that targets DLL4 and VEGF-A, currently in Phase 1b trials. The acquisition will enhance Compass' pipeline, and TRIGR's management will join Compass' board. Closing is anticipated in Q2 2021, with considerations including 10,265,154 shares issued to TRIGR shareholders.

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Compass Therapeutics (CMPX) reported its 2020 financial results, highlighting a net loss of $29.5 million, a decrease from $34.7 million in 2019. The company successfully completed a $60.5 million private placement, enabling its transition to a public entity and OTCQB listing. Clinical progress includes the Phase 1b expansion of the CTX-471 study, showing promising anti-tumor activity, with data expected in the second half of 2021. Cash and cash equivalents stood at $47.1 million, providing operational runway until Q2 2022.

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FAQ

What is the current stock price of Compass Therapeutics (CMPX)?

The current stock price of Compass Therapeutics (CMPX) is $1.38 as of December 20, 2024.

What is the market cap of Compass Therapeutics (CMPX)?

The market cap of Compass Therapeutics (CMPX) is approximately 200.2M.

What does Compass Therapeutics, Inc. specialize in?

Compass Therapeutics specializes in developing proprietary antibody-based therapeutics to treat a variety of human diseases, with a focus on oncology.

What are the main product candidates of Compass Therapeutics?

The main product candidates are CTX-009 (DLL4 and VEGF-A bispecific antibody), CTX-471 (CD137 agonist), and CTX-8371 (PD-1 x PD-L1 bispecific antibody).

What recent milestones has Compass Therapeutics achieved?

Compass has reported top-line data from its Phase 2 and Phase 2/3 trials and received FDA Fast Track Designation for CTX-009 in combination with paclitaxel for BTC. They also dosed the first patient in a Phase 1 trial of CTX-8371.

Where is Compass Therapeutics headquartered?

Compass Therapeutics is headquartered in Boston, Massachusetts.

How is Compass Therapeutics financed?

The company secured $120 million in Series A financing in 2015 and ended 2023 with $152 million in cash, providing a cash runway into mid-2026.

Who are the key executives at Compass Therapeutics?

Key executives include Vered Bisker-Leib, PhD, Chief Executive Officer, and Thomas Schuetz, MD, PhD, Co-Founder, President of R&D, and Vice Chairman of the Board.

What is the scientific focus of Compass Therapeutics?

Compass focuses on the relationship between angiogenesis, the immune system, and tumor growth, targeting multiple critical biological pathways for an effective anti-tumor response.

What is the financial condition of Compass Therapeutics?

Compass ended the year 2023 with $152 million in cash and marketable securities, projecting a cash runway into mid-2026.

How does Compass Therapeutics innovate in antibody discovery?

Compass employs a partnership-first mentality, using best-in-class technologies and top-tier academic collaborations to industrialize antibody discovery and decentralize biologic validation.

What therapeutic areas is Compass Therapeutics exploring?

Compass explores treatments for various cancers, including advanced biliary tract cancer, colorectal cancer, melanoma, and non-small cell lung cancer, among others.

Compass Therapeutics, Inc.

Nasdaq:CMPX

CMPX Rankings

CMPX Stock Data

200.19M
97.93M
12.04%
71.79%
0.89%
Biotechnology
Biological Products, (no Disgnostic Substances)
Link
United States of America
BOSTON