Core One Labs' Scientists Successfully Complete Breakthrough First Step in Producing API-Grade DMT
Core One Labs Inc. (OTCQB:CLABF) announces significant progress by its subsidiary, Awakened Biosciences, in producing DMT, with a successful synthesis of a precursor. Approximately 25 grams of this precursor can yield around 15 grams of contaminant-free DMT. This advancement positions Core One as a potential leader in the psychedelics market. Additionally, Akome Biotech, another subsidiary, is working on two DMT-based drug formulations aimed at treating ischemic stroke and Parkinson's Disease, addressing pressing global health issues.
- Successful production of a DMT precursor, enhancing future API-grade DMT production.
- Positioning as a leader in the psychedelics market with growing demand for DMT-based medicines.
- Development of two patent-pending DMT formulations targeting significant health conditions.
- None.
Second Ground Breaking Technological Advancement
VANCOUVER, BC / ACCESSWIRE / September 2, 2022 / Core One Labs Inc. (CSE:COOL), (OTCQB:CLABF), (Frankfurt:LD6)(WKN:A3CSSU) (the "Company" or "Core One") is pleased to announce that scientists at its wholly-owned subsidiary Awakened Biosciences Inc. ("Awakened") have successfully completed the breakthrough first step in producing API N, N-dimethyltryptamine (DMT), with the synthesis of a DMT precursor (the "Precursor").
Awakened's Chief Researcher, Dr. Tony Durst, has produced approximately 25 grams (g) of the precursor, and anticipates that the 25g sample can be successfully converted into DMT API product at a high yield, resulting in approximately 15g of contaminant-free DMT API end product. This is Core One's second groundbreaking technological advancement, thanks to the brilliant minds at Awakened. Their efficiency in producing viable psychedelic API compounds will strengthen the Company's position as pioneers in the psychedelics space.
"Now Core One Labs is not only able to produce API grade psilocybin, but it has achieved a significant breakthrough towards producing cost effective API grade DMT. This has been something we have been working on for quite some time now with our team of scientists at Awakened, and the success of this procedure moves Core One Labs and its subsidiaries a step closer towards becoming a major producer and supplier of psychedelic medicines in the industry, with the goal of being the "go to" supplier for API grade psychedelic input materials for companies producing pharmaceutical drugs," stated Joel Shacker, Core One Labs CEO.
With scientific evidence amounting and supporting DMT's medicinal benefits as a rapid-acting and long-lasting antidepressant, numerous biotechnology and pharmaceutical companies have turned a great deal of attention towards furthering research and development of effective DMT-based therapies and the production of API-grade DMT drug formulations. As demand increases for viable DMT-based medicine, companies are rushing to capitalize on the psychedelic industry's promising outlook. Awakened's successful production of a DMT precursor that could effectively be converted into API DMT positions Core One as a burgeoning leader for the provision of Good Manufacturing Practice (GMP) DMT API once pharmaceutical drugs go into production.
In addition to Awakened, Core One Labs' subsidiary, Akome Biotech Ltd. ("Akome"), is also working with DMT, and is currently in pre-clinical development of two patent-pending DMT-based drug formulations, AKO001 and AKO004, which are designed to target Ischemic Stroke ("stroke") and Parkinson's Disease ("PD"), respectively.
It is estimated that 15 million people worldwide suffer a stroke each year, with approximately 5 million dying and another 5 million being permanently disabled as a result.[1] The statistics for Parkinson's disease, are also staggering, with global, disability and death due to PD increasing faster than for any other neurological disorder. The prevalence of PD has doubled in the past 25 years. Global estimates in 2019 showed over 8.5 million individuals with PD. Current estimates suggest that, in 2019, PD resulted in 5.8 million disability-adjusted life years, an increase of
The studies being conducted on Akome's DMT-based drug formulations have presented very promising results to date, and a viable, cost effective DMP API product produced by Awakened, would afford Akome to incorporate the Company's proprietary psychedelic compounds into furthering progress of its pre-clinical drug development studies, and capitalize on a reduction in research costs.
About N, N-dimethyltryptamine (DMT)
DMT is a naturally occurring psychedelic substance found in plants and in the brain of mammals. The compound is a primary component of traditional South American entheogenic brews and is traditionally derived from the leaves of a variety of plants endemic to equatorial regions across the globe. DMT is currently under clinical investigation for the treatment of certain mood disorders and in patients with Major Depressive Disorder (MDD).
About Core One Labs Inc.
Core One Labs is a life sciences biotechnology research and development company focused on bringing psychedelic medicines to market through the development and production of psychedelic compounds, the advancement of psychedelic assisted treatments, and the integration of novel delivery systems technology.
The Company has a multi-faceted business approach and incorporates several complementary lines of businesses and units in establishing itself as an industry leader in the rapidly growing and emerging psychedelics market space.
Core One, through its wholly owned subsidiary Vocan Biotechnologies Inc., has developed and filed for patent protection of a proprietary psilocybin production system using engineered bacteria. It is also the holder of 4 provisional patents for the development of psychedelic-based pharmaceutical formulations targeting neurological and mental health disorders, under its
In addition to the development of psychedelics and psychedelic compounds, Core One holds an interest in four medical clinics which maintain a combined database of more than 275,000 patients. Through its clinics the Company intends to integrate a roll out of its intellectual property related to psychedelic technologies and participate in the advancement of psychedelic-based treatments for mental health disorders.
Core One Labs Inc.
Joel Shacker
Chief Executive Officer
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Cautionary Disclaimer Statement:
The Canadian Securities Exchange has not reviewed and does not accept responsibility for the adequacy or accuracy of the content of this news release.
Information set forth in this news release contains forward-looking statements that are based on assumptions as of the date of this news release. These statements reflect management's current estimates, beliefs, intentions, and expectations. They are not guarantees of future performance. The Company cautions that all forward-looking statements are inherently uncertain, and that actual performance may be affected by a number of material factors, many of which are beyond the Company's control. Such factors include, among other things: risks and uncertainties relating to the Company's limited operating history and the need to comply with strict regulatory regulations. Accordingly, actual and future events, conditions and results may differ materially from the estimates, beliefs, intentions and expectations expressed or implied in the forward-looking information. Except as required under applicable securities legislation, the Company undertakes no obligation to publicly update or revise forward-looking information.
In addition, psilocybin is currently a Schedule III drug under the Controlled Drugs and Substances Act (Canada) and it is a criminal offence to possess substances under the Controlled Drugs and Substances Act (Canada) without a prescription or authorization. Health Canada has not approved psilocybin as a drug for any indication. Core One does not have any direct or indirect involvement with illegal selling, production, or distribution of psychedelic substances in jurisdictions in which it operates. While Core One believes psychedelic substances can be used to treat certain medical conditions, it does not advocate for the legalization of psychedelics substances for recreational use. Core One does not deal with psychedelic substances, except within laboratory and clinical trial settings conducted within approved regulatory frameworks.
[1] http://www.emro.who.int/health-topics/stroke-cerebrovascular-accident/index.html
[2] https://www.who.int/news-room/fact-sheets/detail/parkinson-disease
SOURCE: Core One Labs Inc.
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FAQ
What is the recent breakthrough reported by Core One Labs regarding DMT?
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