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Cullinan Therapeutics, Inc. - CGEM STOCK NEWS

Welcome to our dedicated page for Cullinan Therapeutics news (Ticker: CGEM), a resource for investors and traders seeking the latest updates and insights on Cullinan Therapeutics stock.

Cullinan Therapeutics, Inc. (Nasdaq: CGEM) is a forward-thinking biopharmaceutical company dedicated to establishing new standards of care for patients through innovative cancer and autoimmune therapies. The company specializes in a modality-agnostic approach, targeting key drivers of disease and harnessing the immune system to eradicate diseased cells.

With a highly experienced team of oncology professionals and drug developers, Cullinan boasts a diversified portfolio of clinical-stage assets sourced from both internal and external collaborations. This includes therapies aimed at inhibiting disease drivers or activating the immune system to address various oncology and autoimmune indications.

Recent Achievements:

  • CLN-617: A first-in-class cytokine therapy combining IL-2 and IL-12 for intratumoral injection, shown to activate a broad immune response.
  • CLN-619: A first-in-class monoclonal antibody for relapsed/refractory multiple myeloma, aimed at restoring immune recognition of tumor cells.
  • CLN-978: A novel CD19xCD3 bispecific T cell engager being developed for systemic lupus erythematosus.
  • Zipalertinib: An EGFR inhibitor for non-small cell lung cancer, with promising efficacy and a manageable safety profile.

Financially, Cullinan is well-positioned, having announced a $280 million private placement to support ongoing research and development activities. This funding, combined with current assets, is expected to sustain the company's operations into 2028.

For more detailed insights and updates, visit Cullinan’s website or follow them on LinkedIn and Twitter.

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On February 2, 2023, Cullinan Oncology (Nasdaq: CGEM) announced that President and CEO Nadim Ahmed will participate in two major conferences this February. He will engage in a fireside chat at Guggenheim’s 5th Annual Oncology Conference on February 8, 2023, at 1:00 p.m. EST, and at the SVB Securities Global Biopharma Conference on February 15, 2023, at 10:40 a.m. EST. Live webcasts of these sessions will be available on the Company's investor relations website. Investors can also arrange one-on-one meetings with management during these events.

Cullinan Oncology aims to innovate cancer therapies across various modalities and partners with academic and industry leaders to enhance cancer treatment.

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Cullinan Oncology, Inc. (Nasdaq: CGEM) announced the granting of stock options to three new employees, totaling 56,000 shares. The options, part of a Nasdaq inducement plan, have an exercise price of $11.58, matching the stock's closing price on February 1, 2023. Each option features a ten-year term with a vesting schedule: 25% vesting after the first year, followed by equal monthly installments over the next three years, contingent on continued employment. This move aims to attract talent and incentivize long-term commitment among staff as Cullinan focuses on innovative cancer therapies.

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Cullinan Oncology, Inc. (Nasdaq: CGEM) announced that the FDA has cleared its IND application for CLN-978, a bispecific antibody targeting CD19/CD3. This construct is designed for the treatment of relapsed/refractory B-cell non-Hodgkin lymphoma (B-NHL). The Phase 1 trial will assess the safety and efficacy of CLN-978, which features a novel design for improved potency and subcutaneous delivery. This marks Cullinan's fourth clinical-stage asset and underscores its dedication to enhancing cancer treatment standards. Furthermore, the IND submission for CLN-617 is anticipated in the first half of 2023.

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Cullinan Oncology, a biopharmaceutical focused on cancer therapies, announced the grant of stock options for 86,000 shares to three new employees outside its 2021 Incentive Plan. The options were awarded on December 1, 2022, at an exercise price of $12.26, matching the stock's closing price on that day. Each option will vest over four years, beginning with 25% on the first anniversary. These actions comply with Nasdaq Listing Rule 5635(c)(4), designed to facilitate talent acquisition in line with their growth strategy.

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Cullinan Oncology (CGEM) has initiated a pivotal study for zipalertinib in patients with EGFR exon 20 non-small cell lung cancer. The company has increased its ownership in MICA subsidiary from 54% to 92%. Initial clinical data updates for the CLN-049 and CLN-619 programs are expected in mid-2023. As of September 30, 2022, Cullinan has approximately $607 million in cash and investments. The third quarter net loss was $24.9 million, with R&D expenses decreasing to $19.7 million. Leadership changes include the appointment of Jacquelyn Sumer as Chief Legal Officer.

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Cullinan Oncology (NASDAQ: CGEM) announced the appointment of Dr. David P. Ryan to its Board of Directors, effective immediately. Dr. Ryan has over 20 years of experience in oncology, currently serving as Clinical Director at Massachusetts General Hospital Cancer Center. He replaces Dr. Ansbert Gadicke, a founding member, who has been instrumental in the company’s transition to a public entity since 2016. Dr. Ryan's expertise in clinical research and gastrointestinal malignancies is expected to support Cullinan's diverse oncology pipeline.

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Cullinan Oncology, Inc. (Nasdaq: CGEM) announced the granting of stock options for 147,000 shares to four new employees on November 1, 2022. The options, issued outside of its 2021 Stock Option and Incentive Plan, feature an exercise price of $13.26, matching the company's closing stock price on the grant date. Each option vests over four years, with the first installment vesting after one year. This grant follows Nasdaq Listing Rule 5635(c)(4), aimed at incentivizing new hires as Cullinan continues its focus on developing targeted oncology therapies.

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Cullinan Oncology (Nasdaq: CGEM) has announced its participation in several upcoming investor conferences. CFO Jeff Trigilio will present at the Credit Suisse 31st Annual Healthcare Conference on November 8, 2022, at 11:35 a.m. EST. CEO Nadim Ahmed will speak at the Stifel 2022 Healthcare Conference in New York on November 16, 2022, at 4:45 p.m. EST, and will also participate in a virtual fireside chat at the Evercore ISI 5th Annual HEALTHCONx conference on December 1, 2022, at 8:25 a.m. EST. Webcasts of these events will be available on the company's investor relations website.

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Cullinan Oncology, Inc. (Nasdaq: CGEM) has increased its ownership in Cullinan MICA, Inc. from 54% to 92% after acquiring shares from financial investors Avalon Ventures and Bregua Corporation for $30.7 million. This strategic move emphasizes the importance of CLN-619, an antibody designed to enhance tumor cell destruction by immune cells, in Cullinan's cancer treatment pipeline. The ongoing Phase I clinical trial of CLN-619 aims to report initial data in mid-2023, highlighting its potential as a first-in-class therapy for various cancers.

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Cullinan Oncology (Nasdaq: CGEM) announced on October 3, 2022, that its Board of Directors granted stock options for 242,000 shares of common stock to seven employees. This grant is part of an inducement offer for new hires, aligning with Nasdaq Listing Rule 5635(c)(4). The options have an exercise price of $12.83, matching the closing stock price on the grant date. Each option has a ten-year term, vesting over four years, with a quarter vesting after one year and the remainder in equal monthly installments over the following 36 months.

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FAQ

What is the current stock price of Cullinan Therapeutics (CGEM)?

The current stock price of Cullinan Therapeutics (CGEM) is $13.86 as of November 15, 2024.

What is the market cap of Cullinan Therapeutics (CGEM)?

The market cap of Cullinan Therapeutics (CGEM) is approximately 827.4M.

What does Cullinan Therapeutics, Inc. specialize in?

Cullinan Therapeutics, Inc. specializes in developing innovative cancer and autoimmune therapies, utilizing a modality-agnostic approach to target key drivers of disease and harness the immune system.

What is CLN-617?

CLN-617 is a first-in-class cytokine therapy combining IL-2 and IL-12 for intratumoral injection, designed to activate a broad immune response against cancer cells.

What is the purpose of the recent $280 million private placement?

The $280 million private placement is intended to support Cullinan’s ongoing research and development activities, expand its clinical programs, and fund general corporate purposes and working capital.

What is Zipalertinib?

Zipalertinib is an orally available EGFR inhibitor designed to target exon 20 insertion mutations in non-small cell lung cancer, demonstrating promising efficacy and a manageable safety profile.

What are the latest developments regarding CLN-619?

CLN-619 is a monoclonal antibody targeting relapsed/refractory multiple myeloma, with Phase 1 trials indicating its potential to restore immune recognition and attack tumor cells.

What types of diseases does Cullinan Therapeutics' portfolio address?

Cullinan’s portfolio addresses both oncology and autoimmune diseases through a range of modalities designed to inhibit disease drivers or activate the immune system.

What is the strategic focus of Cullinan Therapeutics?

Cullinan focuses on creating transformative therapeutics by identifying unique targets and selecting optimal modalities, leveraging deep expertise in oncology, immunology, and translational medicine.

What is CLN-978 and its target indication?

CLN-978 is a novel CD19xCD3 bispecific T cell engager aimed at treating systemic lupus erythematosus and potentially other autoimmune diseases.

How does Cullinan Therapeutics ensure the development of promising assets?

Cullinan applies rigorous go/no-go criteria at each development stage to fast-track only the most promising molecules from candidate selection to clinical and commercial stages.

Where can I find more information about Cullinan Therapeutics?

More information about Cullinan Therapeutics can be found on their website at www.cullinantherapeutics.com and by following them on LinkedIn and Twitter.

Cullinan Therapeutics, Inc.

Nasdaq:CGEM

CGEM Rankings

CGEM Stock Data

827.41M
58.23M
4.5%
114.91%
15.63%
Biotechnology
Biological Products, (no Disgnostic Substances)
Link
United States of America
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