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Cullinan Therapeutics, Inc. - CGEM STOCK NEWS

Welcome to our dedicated page for Cullinan Therapeutics news (Ticker: CGEM), a resource for investors and traders seeking the latest updates and insights on Cullinan Therapeutics stock.

Cullinan Therapeutics, Inc. (Nasdaq: CGEM) is a forward-thinking biopharmaceutical company dedicated to establishing new standards of care for patients through innovative cancer and autoimmune therapies. The company specializes in a modality-agnostic approach, targeting key drivers of disease and harnessing the immune system to eradicate diseased cells.

With a highly experienced team of oncology professionals and drug developers, Cullinan boasts a diversified portfolio of clinical-stage assets sourced from both internal and external collaborations. This includes therapies aimed at inhibiting disease drivers or activating the immune system to address various oncology and autoimmune indications.

Recent Achievements:

  • CLN-617: A first-in-class cytokine therapy combining IL-2 and IL-12 for intratumoral injection, shown to activate a broad immune response.
  • CLN-619: A first-in-class monoclonal antibody for relapsed/refractory multiple myeloma, aimed at restoring immune recognition of tumor cells.
  • CLN-978: A novel CD19xCD3 bispecific T cell engager being developed for systemic lupus erythematosus.
  • Zipalertinib: An EGFR inhibitor for non-small cell lung cancer, with promising efficacy and a manageable safety profile.

Financially, Cullinan is well-positioned, having announced a $280 million private placement to support ongoing research and development activities. This funding, combined with current assets, is expected to sustain the company's operations into 2028.

For more detailed insights and updates, visit Cullinan’s website or follow them on LinkedIn and Twitter.

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Cullinan Oncology (Nasdaq: CGEM) announced that Jon Wigginton, M.D. will step down as Chief Medical Officer to assume the role of Chairman of the Scientific Advisory Board and Senior Advisor to the CEO. CEO Owen Hughes acknowledged Wigginton's significant contributions to the company's transition to a clinical-stage biotech and the establishment of its clinical infrastructure. Wigginton expressed his enthusiasm to continue working closely with Cullinan's team to advance their innovative cancer therapies.

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Cullinan Oncology (Nasdaq: CGEM) has announced a clinical update on its investigational oral EGFR inhibitor, CLN-081, during a webinar on June 4, 2021. The update will review safety and efficacy results from an ongoing Phase 1/2a trial for Non-Small Cell Lung Cancer (NSCLC) patients with EGFR Exon 20 insertion mutations. Data from this trial will also be presented at the 2021 ASCO Annual Meeting. The webinar and poster will take place on the same day, with the poster accessible for on-demand viewing starting at 9:00 am ET.

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Cullinan Oncology, Inc. (Nasdaq: CGEM) reported its Q1 2021 financial results, highlighting cash reserves of $473 million as of March 31, 2021, significantly up from $210.2 million at year-end 2020. The company initiated a Phase 2a expansion of its Cullinan Pearl trial for NSCLC patients with EGFRex20ins mutations and plans to present updated data at the 2021 ASCO Annual Meeting. Q1 expenses included $12.4 million in R&D and $5.2 million in G&A. Net income was reported at $1.4 million, driven by $18.9 million revenue from its license agreement with Zai Lab.

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Cullinan Oncology (Nasdaq: CGEM) has announced that CFO Jeff Trigilio will present at the 20th Annual Needham Virtual Healthcare Conference on April 13, 2021, at 11:45 am EDT. The presentation will be accessible only to registered attendees through the Needham conference portal. Interested investors can schedule meetings with Trigilio by contacting their Needham representative. Cullinan Oncology is focused on developing a diversified pipeline of targeted and immuno-oncology therapeutic candidates to drive shareholder returns.

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Cullinan Oncology reported its financial results for the year ended December 31, 2020, highlighting significant advancements in its clinical pipeline and financial metrics. The company completed a Series C financing of $131.2 million and an IPO raising $287.4 million, enhancing its cash position to $210.2 million. Clinical progress includes the initiation of Phase 2a for CLN-081 in NSCLC with promising outcomes. R&D expenses totaled $43.2 million, contributing to a net loss of $59.5 million, influenced by non-cash charges. Strategic hires and partnerships underscore Cullinan's commitment to advancing immuno-oncology assets.

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Cullinan Oncology (Nasdaq: CGEM) has announced that its CEO, Owen Hughes, will present at the H.C. Wainwright Global Life Sciences Conference on March 9, 2021, at 7:00 AM EST. The presentation will be available on-demand for registered attendees starting at that time. Cullinan specializes in developing a diverse pipeline of targeted oncology and immuno-oncology therapies, focusing on candidates with novel technology and advanced development stages.

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Cullinan Management, Inc. (Nasdaq: CGEM) has announced significant updates regarding its oncology pipeline. The company plans to expand enrollment in the Phase 1/2a trial of CLN-081 for NSCLC patients with EGFR exon 20 insertions, allowing 36 patients total. Cullinan has withdrawn its IND for CLN-049 in AML due to FDA feedback, while an IND submission for CLN-619 is planned for Q2 2021. CEO Owen Hughes will present at the SVB Leerink Global Healthcare Conference on February 26, 2021.

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Cullinan Management (Nasdaq: CGEM) has successfully closed its initial public offering, selling 13,685,000 shares at $21.00 each, resulting in gross proceeds of $287.4 million. This offering included 1,785,000 shares exercised by underwriters. The shares started trading on the Nasdaq Global Select Market on January 8, 2021. Morgan Stanley, SVB Leerink, and Evercore served as joint book-running managers. The press release emphasizes Cullinan's focus on developing a robust pipeline of oncology and immuno-oncology therapies.

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Cullinan Management has announced the pricing of its upsized initial public offering (IPO) of 11,900,000 shares at $21.00 per share, aiming to raise approximately $249.9 million before expenses. The underwriters also have a 30-day option to purchase an additional 1,785,000 shares. Shares will begin trading on the Nasdaq Global Select Market under the symbol “CGEM” on January 8, 2021, with the offering expected to close on January 12, 2021. Morgan Stanley, SVB Leerink, and Evercore Group are joint book-running managers for the offering.

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Cullinan Management, a biopharmaceutical company, has announced the pricing of its upsized initial public offering of 11,900,000 shares at $21.00 each, aiming to raise approximately $249.9 million before expenses. The shares will begin trading on The Nasdaq under the symbol CGEM on January 8, 2021, with the offering expected to close on January 12, 2021. The company focuses on developing targeted oncology and immuno-oncology therapies with transformative potential for cancer patients.

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FAQ

What is the current stock price of Cullinan Therapeutics (CGEM)?

The current stock price of Cullinan Therapeutics (CGEM) is $11.6 as of December 20, 2024.

What is the market cap of Cullinan Therapeutics (CGEM)?

The market cap of Cullinan Therapeutics (CGEM) is approximately 684.2M.

What does Cullinan Therapeutics, Inc. specialize in?

Cullinan Therapeutics, Inc. specializes in developing innovative cancer and autoimmune therapies, utilizing a modality-agnostic approach to target key drivers of disease and harness the immune system.

What is CLN-617?

CLN-617 is a first-in-class cytokine therapy combining IL-2 and IL-12 for intratumoral injection, designed to activate a broad immune response against cancer cells.

What is the purpose of the recent $280 million private placement?

The $280 million private placement is intended to support Cullinan’s ongoing research and development activities, expand its clinical programs, and fund general corporate purposes and working capital.

What is Zipalertinib?

Zipalertinib is an orally available EGFR inhibitor designed to target exon 20 insertion mutations in non-small cell lung cancer, demonstrating promising efficacy and a manageable safety profile.

What are the latest developments regarding CLN-619?

CLN-619 is a monoclonal antibody targeting relapsed/refractory multiple myeloma, with Phase 1 trials indicating its potential to restore immune recognition and attack tumor cells.

What types of diseases does Cullinan Therapeutics' portfolio address?

Cullinan’s portfolio addresses both oncology and autoimmune diseases through a range of modalities designed to inhibit disease drivers or activate the immune system.

What is the strategic focus of Cullinan Therapeutics?

Cullinan focuses on creating transformative therapeutics by identifying unique targets and selecting optimal modalities, leveraging deep expertise in oncology, immunology, and translational medicine.

What is CLN-978 and its target indication?

CLN-978 is a novel CD19xCD3 bispecific T cell engager aimed at treating systemic lupus erythematosus and potentially other autoimmune diseases.

How does Cullinan Therapeutics ensure the development of promising assets?

Cullinan applies rigorous go/no-go criteria at each development stage to fast-track only the most promising molecules from candidate selection to clinical and commercial stages.

Where can I find more information about Cullinan Therapeutics?

More information about Cullinan Therapeutics can be found on their website at www.cullinantherapeutics.com and by following them on LinkedIn and Twitter.

Cullinan Therapeutics, Inc.

Nasdaq:CGEM

CGEM Rankings

CGEM Stock Data

684.17M
52.75M
4.5%
118.78%
14.96%
Biotechnology
Biological Products, (no Disgnostic Substances)
Link
United States of America
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