CareDx Presents Landmark KOAR-1000 Data, Demonstrating Higher 1-Year Graft Survival and Reduction in Biopsies through ARTS Surveillance

Rhea-AI Summary

CareDx announced its participation in the American Transplant Congress (ATC) 2021, showcasing data from the Kidney Outcomes with AlloSure Registry (KOAR). This study, the largest of its kind, enrolled over 1,500 kidney transplant patients across 50 centers. Key findings reveal improved one-year graft survival rates and a reduction in biopsy procedures compared to traditional methods. The presentation aims to highlight AlloSure's effectiveness in monitoring transplant health and its role in enhancing patient care.

Positive

• One-year graft survival for AlloSure monitored patients was higher than national averages.
• AlloSure reduces the number of biopsies compared to creatinine-guided biopsies.
• The study included a large cohort of over 1,500 patients, enhancing data reliability.

Negative

• None.

KOAR is the largest prospective validation study on AlloSure surveillance with over 1,500 patients enrolled

SOUTH SAN FRANCISCO, Calif., June 07, 2021 (GLOBE NEWSWIRE) -- CareDx, Inc. (Nasdaq: CDNA), a leading precision medicine company focused on the discovery, development, and commercialization of clinically differentiated, high-value healthcare solutions for transplant patients and caregivers, today announced an analysis of one-year data from the first 1000 patients enrolled in the Kidney Outcomes with AlloSure Registry (KOAR) will be presented at the American Transplant Congress (ATC) 2021, which is taking place between June 4-9, 2021.

The KOAR Study, which includes more than 1,500 kidney transplant patients from over 50 transplant centers, is the largest prospective study of AlloSure dd-cfDNA.

Key findings from KOAR include:

• One-year graft survival among patients monitored with AlloSure was higher than those of patients reported in the national UNOS Registry Data
• AlloSure significantly reduces the number of biopsies performed when compared to biopsies guided by creatinine
• AlloSure discriminates rejection from no rejection in both routine surveillance and for-cause groups
  

CareDx will present the KOAR Study data during its virtual symposium, “Advancing Care in Kidney Transplantation—Groundbreaking Findings from the ADMIRAL and KOAR Studies,” on June 7 from 1:30-2:30 p.m. EDT.

“ATC is one of the premier events for clinicians and scientists in transplantation to come together and share the best the field has to offer,” said Stanley C. Jordan, MD, Cedars-Sinai Medical Center. “I’m thrilled to share our latest data on KOAR. It’s most rewarding to see scientific innovations making a meaningful impact on patient care.”

“KOAR is groundbreaking on multiple levels. To have 50 transplant centers on the same protocol for a true patient comparison is unparalleled. The data is now undisputed. Surveillance AlloSure is a valuable improvement to the standard of care for transplant patients,” said Sham Dholakia, MD, SVP Medical Affairs, CareDx.

About CareDx
CareDx, Inc., headquartered in South San Francisco, California, is a leading precision medicine solutions company focused on the discovery, development and commercialization of clinically differentiated, high-value healthcare solutions along the pre- and post-transplant patient journey and is the leading provider of genomics-based information for transplant patients. For more information, please visit: www.CareDx.com.

CONTACTS:
CareDx, Inc.
Sasha King
Chief Marketing Officer
415-287-2393
sking@caredx.com

Investor Relations
Greg Chodaczek
347-620-7010
investor@caredx.com

FAQ

What is the KOAR study presented at ATC 2021?

The KOAR study is the largest prospective study analyzing AlloSure surveillance, involving over 1,500 kidney transplant patients across 50 centers.

What were the key findings from the KOAR study?

The study found higher one-year graft survival rates for patients monitored with AlloSure and a significant reduction in the number of biopsies performed.

When was the KOAR study data presented?

The KOAR study data was presented during a virtual symposium on June 7, 2021, at the ATC.

How does AlloSure improve patient care?

AlloSure enhances patient care by providing effective monitoring that reduces the need for invasive biopsies and improves graft survival rates.

What is the significance of the KOAR study's size?

With over 1,500 participants, the KOAR study provides robust data that supports the effectiveness of AlloSure in kidney transplantation.